ES2156955T3 - Procedimiento para la preparacion de 5-hidroximetiltiazol. - Google Patents
Procedimiento para la preparacion de 5-hidroximetiltiazol.Info
- Publication number
- ES2156955T3 ES2156955T3 ES95940008T ES95940008T ES2156955T3 ES 2156955 T3 ES2156955 T3 ES 2156955T3 ES 95940008 T ES95940008 T ES 95940008T ES 95940008 T ES95940008 T ES 95940008T ES 2156955 T3 ES2156955 T3 ES 2156955T3
- Authority
- ES
- Spain
- Prior art keywords
- preparation
- hydroximethyltiolol
- procedure
- hydroxymethylthiazole
- hydrolyzing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D277/24—Radicals substituted by oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
SE PRESENTA UN PROCEDIMIENTO DE PREPARACION DE 5HIDROXIMETILTIAZOL, QUE COMPRENDE HACER REACCIONAR UN COMPUESTO DE FORMULA (A), CON UNA SAL DE UN ACIDO CARBOXILICO (OPTIMAMENTE EN PRESENCIA DE UNA SAL DE AMONIO CUATERNARIO), E HIDROLIZAR EL ESTER RESULTANTE. LA DECLORACION SUBSIGUIENTE, PRODUCE 5HIDROXIMETILTIAZOL.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US34369094A | 1994-11-22 | 1994-11-22 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2156955T3 true ES2156955T3 (es) | 2001-08-01 |
Family
ID=23347195
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES95940008T Expired - Lifetime ES2156955T3 (es) | 1994-11-22 | 1995-11-15 | Procedimiento para la preparacion de 5-hidroximetiltiazol. |
Country Status (11)
Country | Link |
---|---|
US (1) | US5712400A (es) |
EP (1) | EP0793659B1 (es) |
JP (1) | JPH10509177A (es) |
AT (1) | ATE199714T1 (es) |
DE (1) | DE69520368T2 (es) |
DK (1) | DK0793659T3 (es) |
ES (1) | ES2156955T3 (es) |
GR (1) | GR3035865T3 (es) |
MX (1) | MX9703766A (es) |
PT (1) | PT793659E (es) |
WO (1) | WO1996016050A1 (es) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6265585B1 (en) | 1997-01-22 | 2001-07-24 | Syngenta Crop Protection, Inc. | Process for the preparation of thiazole derivatives |
US5932736A (en) * | 1997-04-07 | 1999-08-03 | Reilly Industries, Inc. | Preparation of heterocycles using 1,3-dihalopropenes |
WO1998045279A1 (en) * | 1997-04-07 | 1998-10-15 | Reilly Industries, Inc. | Preparation of thiazoles using 1,3-dihalopropenes |
US5959118A (en) * | 1997-08-29 | 1999-09-28 | Abbott Laboratories | Process for the preparation of 5-hydroxymethylthiazoles |
US5773625A (en) * | 1997-10-02 | 1998-06-30 | Abbott Laboratories | Process for the preparation of disubstituted carbonates |
US6765019B1 (en) | 1999-05-06 | 2004-07-20 | University Of Kentucky Research Foundation | Permeable, water soluble, non-irritating prodrugs of chemotherapeutic agents with oxaalkanoic acids |
CN101260100A (zh) * | 2008-04-21 | 2008-09-10 | 湖南有色凯铂生物药业有限公司 | 一种5-羟甲基噻唑的制备方法 |
CN101863853B (zh) * | 2009-12-28 | 2012-12-19 | 安徽贝克联合制药有限公司 | 一锅煮法制备5-羟甲基噻唑工艺 |
BR112020008124A2 (pt) | 2017-10-27 | 2020-10-06 | Syngenta Participations Ag | composições de controle de vetores, métodos e produtos utilizando as mesmas |
CN116375662A (zh) * | 2022-12-30 | 2023-07-04 | 新沂市砥研医药技术研究院有限公司 | 一种高效的5-羟甲基噻唑医药中间体的纯化工艺 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4247464A (en) * | 1979-10-01 | 1981-01-27 | General Electric Company | Liquid extraction method for recovering aromatic bisimides |
DE3631538A1 (de) * | 1986-09-17 | 1988-03-24 | Bayer Ag | Verfahren zur herstellung von 2-chlor-5-chlormethylthiazol |
JPS63165334A (ja) * | 1986-12-27 | 1988-07-08 | Hodogaya Chem Co Ltd | 2,6−ジクロロベンジルアルコ−ルの製造法 |
IE20010533A1 (en) * | 1990-11-20 | 2003-03-05 | Abbott Lab | Intermediates for preparing retroviral protease inhibiting compounds |
ATE417836T1 (de) * | 1992-12-29 | 2009-01-15 | Abbott Lab | Verfahren und intermediate zur herstellung von retroviralen proteasehemmern |
-
1995
- 1995-11-15 EP EP95940008A patent/EP0793659B1/en not_active Expired - Lifetime
- 1995-11-15 DE DE69520368T patent/DE69520368T2/de not_active Expired - Fee Related
- 1995-11-15 WO PCT/US1995/014930 patent/WO1996016050A1/en active IP Right Grant
- 1995-11-15 JP JP8516978A patent/JPH10509177A/ja not_active Ceased
- 1995-11-15 PT PT95940008T patent/PT793659E/pt unknown
- 1995-11-15 ES ES95940008T patent/ES2156955T3/es not_active Expired - Lifetime
- 1995-11-15 AT AT95940008T patent/ATE199714T1/de not_active IP Right Cessation
- 1995-11-15 DK DK95940008T patent/DK0793659T3/da active
- 1995-11-15 MX MX9703766A patent/MX9703766A/es unknown
-
1996
- 1996-05-22 US US08/651,439 patent/US5712400A/en not_active Expired - Fee Related
-
2001
- 2001-05-15 GR GR20010400716T patent/GR3035865T3/el not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
GR3035865T3 (en) | 2001-08-31 |
PT793659E (pt) | 2001-07-31 |
MX9703766A (es) | 1997-08-30 |
US5712400A (en) | 1998-01-27 |
EP0793659B1 (en) | 2001-03-14 |
JPH10509177A (ja) | 1998-09-08 |
ATE199714T1 (de) | 2001-03-15 |
DE69520368T2 (de) | 2001-06-28 |
EP0793659A1 (en) | 1997-09-10 |
WO1996016050A1 (en) | 1996-05-30 |
DK0793659T3 (da) | 2001-06-11 |
DE69520368D1 (de) | 2001-04-19 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
MX9604882A (es) | Procedimiento para la preparacion de dihaloazolopirimidinas. | |
CA2065476A1 (en) | Optically active secondary amine compound, process for producing optically active secondary amine compound and process for producing optically active carboxylic acid by using saidcompound | |
EP0742209A3 (en) | Process for the preparation of an optically active quinoline demevalonolacton and process for the preparation of a salt of an optically active quinoline demevalolon | |
ES2156955T3 (es) | Procedimiento para la preparacion de 5-hidroximetiltiazol. | |
AU8268591A (en) | Codeine salt of a substituted carboxylic acid, processes for the preparation thereof, its use and pharmaceutical compositions | |
BR9913670B1 (pt) | processo para a preparação de um sal de um composto de ácido carboxìlico alifático. | |
AU8913091A (en) | Process for producing amino carboxylic acid salt | |
ES2039272T3 (es) | Sales opticamente activas a base de un tiazolidin-4-carboxilato sustituido y 3-cloro-2-hidroxipropiltrimetilamonio, su preparacion y empleo. | |
BR9400016A (pt) | Processo para preparação de compostos, e compostos | |
AU4048701A (en) | Process for preparing alkylene diamine triacetic acid | |
AU562643B2 (en) | N-arylpiperazine derivatives | |
ES2020145A6 (es) | Procedimiento de obtencion de esteres del acido 2-(2,6-diclorofenil)amino) fenilacetoxiacetico. | |
ES2104208T3 (es) | Procedimiento para la preparacion de derivados de acido 3beta-aminocolanico. | |
BR9405186A (pt) | Processo para a preparação de 2,4,5-tribromopirrol-3-carbonitrila | |
PT798297E (pt) | "processo para a producao de 2-alcoxi-6-(trifluorometil)-pirimidin-4-ol" | |
PT99378A (pt) | Processo para a preparacao de intermediarios uteis para a preparacao de acido 4,5-difluoroantranilico | |
PL311582A1 (en) | Method of obtaining n,g-monoalkyl-l-arginin and affinite compounds | |
EP0208281A3 (en) | Quinoline 8-carboxylic-acid azolides, process for their preparation and their use as herbicides | |
ES2129349A1 (es) | Procedimiento para preparar granisetron. | |
ZA965092B (en) | Process for the preparation of alpha-methyl-thiopheneacetic acid derivatives | |
CA2201604A1 (en) | Process for preparing n,n'-difluorodiazoniabicycloalkane salt, intermediate therefor, product and use of product | |
IT1270834B (it) | Disolfuro chinolico | |
IT1270642B (it) | Derivato di acido antranilico ad attivita' immunostimolante | |
GR970100090A (el) | Διαδικασια παραγωγης 1,2-διμεθυλ-3-υδροξυπυριδ-4-ονης | |
HUP9600941A3 (en) | Process for the preparation of 1-cyclopropyl-6-fluoro-1,4-dihydro-7-[1s,4s]-5-methyl-2,5-diazabicyclo-[2.2.1]hept-2-yl-4-oxo-3-quinolinecarboxylic acid and its salts |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
Ref document number: 793659 Country of ref document: ES |