ES2129349A1 - Procedimiento para preparar granisetron. - Google Patents
Procedimiento para preparar granisetron.Info
- Publication number
- ES2129349A1 ES2129349A1 ES09700270A ES9700270A ES2129349A1 ES 2129349 A1 ES2129349 A1 ES 2129349A1 ES 09700270 A ES09700270 A ES 09700270A ES 9700270 A ES9700270 A ES 9700270A ES 2129349 A1 ES2129349 A1 ES 2129349A1
- Authority
- ES
- Spain
- Prior art keywords
- granisetron
- preparation
- salt
- same
- isocyanate group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Procedimiento para preparar granisetrón haciendo reacciona ácido 1-metilindazol-3-carboxílico o una sal del mismo con un compuesto de la Estructura (3) o una sal del mismo, en la que X representa un grupo de isocianato -NCO, o un grupo que es capaz de generar un grupo de isocianato al calentar, y opcionalmente formar una sal farmacéuticamente aceptable.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB9602862.6A GB9602862D0 (en) | 1996-02-13 | 1996-02-13 | Novel process |
Publications (2)
Publication Number | Publication Date |
---|---|
ES2129349A1 true ES2129349A1 (es) | 1999-06-01 |
ES2129349B1 ES2129349B1 (es) | 2000-01-01 |
Family
ID=10788574
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES9700270A Expired - Fee Related ES2129349B1 (es) | 1996-02-13 | 1997-02-11 | Procedimiento para preparar granisetron. |
Country Status (2)
Country | Link |
---|---|
ES (1) | ES2129349B1 (es) |
GB (1) | GB9602862D0 (es) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2003080606A1 (en) * | 2002-03-26 | 2003-10-02 | Laboratorios Vita, S.A. | Process for preparing a pharmaceutically active compound (granisetron) |
WO2008151677A1 (en) | 2007-06-13 | 2008-12-18 | Inke, S.A. | Polymorphic form of granisetron base, methods for obtaining it and formulation containing it |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0200444A2 (en) * | 1985-04-27 | 1986-11-05 | Beecham Group Plc | Azabicyclononyl-indazole-carboxamide having 5-HT antagonist activity |
EP0214772A1 (en) * | 1985-08-16 | 1987-03-18 | Beecham Group Plc | Novel compounds |
EP0223385A2 (en) * | 1985-10-21 | 1987-05-27 | Beecham Group Plc | 8-Azabicyclo[3,2,1]octane and 9-azabicyclo[3,3,1]nonane derivatives |
WO1995023799A1 (en) * | 1994-03-03 | 1995-09-08 | Smithkline Beecham Plc | Process for the preparation of an indazole-3-carboxamide derivative |
-
1996
- 1996-02-13 GB GBGB9602862.6A patent/GB9602862D0/en active Pending
-
1997
- 1997-02-11 ES ES9700270A patent/ES2129349B1/es not_active Expired - Fee Related
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0200444A2 (en) * | 1985-04-27 | 1986-11-05 | Beecham Group Plc | Azabicyclononyl-indazole-carboxamide having 5-HT antagonist activity |
EP0214772A1 (en) * | 1985-08-16 | 1987-03-18 | Beecham Group Plc | Novel compounds |
EP0223385A2 (en) * | 1985-10-21 | 1987-05-27 | Beecham Group Plc | 8-Azabicyclo[3,2,1]octane and 9-azabicyclo[3,3,1]nonane derivatives |
WO1995023799A1 (en) * | 1994-03-03 | 1995-09-08 | Smithkline Beecham Plc | Process for the preparation of an indazole-3-carboxamide derivative |
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2003080606A1 (en) * | 2002-03-26 | 2003-10-02 | Laboratorios Vita, S.A. | Process for preparing a pharmaceutically active compound (granisetron) |
ES2197001A1 (es) * | 2002-03-26 | 2003-12-16 | Vita Lab | Procedimiento de obtencion de un compuesto farmacuticamente activo. |
US7071209B2 (en) | 2002-03-26 | 2006-07-04 | Laboratorios Vita, S.A. | Process for preparing a pharmaceutically active compound (granisetron) |
WO2008151677A1 (en) | 2007-06-13 | 2008-12-18 | Inke, S.A. | Polymorphic form of granisetron base, methods for obtaining it and formulation containing it |
US8304426B2 (en) | 2007-06-13 | 2012-11-06 | Inke, S.A. | Polymorphic form of Granisetron base, methods for obtaining it and formulation containing it |
Also Published As
Publication number | Publication date |
---|---|
GB9602862D0 (en) | 1996-04-10 |
ES2129349B1 (es) | 2000-01-01 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
EC2A | Search report published |
Date of ref document: 19990601 Kind code of ref document: A1 Effective date: 19990601 |
|
FD2A | Announcement of lapse in spain |
Effective date: 20170526 |