MX9703766A - Procedimiento para la preparacion de 5-hidroximetiltiazol. - Google Patents
Procedimiento para la preparacion de 5-hidroximetiltiazol.Info
- Publication number
- MX9703766A MX9703766A MX9703766A MX9703766A MX9703766A MX 9703766 A MX9703766 A MX 9703766A MX 9703766 A MX9703766 A MX 9703766A MX 9703766 A MX9703766 A MX 9703766A MX 9703766 A MX9703766 A MX 9703766A
- Authority
- MX
- Mexico
- Prior art keywords
- hydroxymethylthiazole
- preparation
- hydrolyzing
- optimally
- gives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D277/24—Radicals substituted by oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
Se describe un procedimiento para la preparacion de 5-hidroximetiltiazol que comprende hacer reaccionar un compuesto de la formula (A) con una sal deácido carboxílico (opcionalmente en presencia de una sal de amonio cuaternario) e hidrolizar el éster resultante. La descloracion subsecuente da 5-hidroximetiltiazol.
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US34369094A | 1994-11-22 | 1994-11-22 | |
US343690 | 1994-11-22 | ||
US343,690 | 1994-11-22 | ||
PCT/US1995/014930 WO1996016050A1 (en) | 1994-11-22 | 1995-11-15 | Process for preparation of 5-hydroxymethylthiazole |
Publications (2)
Publication Number | Publication Date |
---|---|
MXPA97003766A MXPA97003766A (es) | 1997-08-01 |
MX9703766A true MX9703766A (es) | 1997-08-30 |
Family
ID=23347195
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX9703766A MX9703766A (es) | 1994-11-22 | 1995-11-15 | Procedimiento para la preparacion de 5-hidroximetiltiazol. |
Country Status (11)
Country | Link |
---|---|
US (1) | US5712400A (es) |
EP (1) | EP0793659B1 (es) |
JP (1) | JPH10509177A (es) |
AT (1) | ATE199714T1 (es) |
DE (1) | DE69520368T2 (es) |
DK (1) | DK0793659T3 (es) |
ES (1) | ES2156955T3 (es) |
GR (1) | GR3035865T3 (es) |
MX (1) | MX9703766A (es) |
PT (1) | PT793659E (es) |
WO (1) | WO1996016050A1 (es) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL130766A0 (en) | 1997-01-22 | 2001-01-28 | Novartis Ag | Process for the preparation of thiazole derivatives |
AU6965398A (en) * | 1997-04-07 | 1998-10-30 | Reilly Industries, Inc. | Preparation of thiazoles using 1,3-dihalopropenes |
WO1998045277A1 (en) * | 1997-04-07 | 1998-10-15 | Reilly Industries, Inc. | Preparation of heterocycles using 1,3-dihalopropenes |
US5959118A (en) * | 1997-08-29 | 1999-09-28 | Abbott Laboratories | Process for the preparation of 5-hydroxymethylthiazoles |
US5773625A (en) * | 1997-10-02 | 1998-06-30 | Abbott Laboratories | Process for the preparation of disubstituted carbonates |
US6765019B1 (en) * | 1999-05-06 | 2004-07-20 | University Of Kentucky Research Foundation | Permeable, water soluble, non-irritating prodrugs of chemotherapeutic agents with oxaalkanoic acids |
CN101260100A (zh) * | 2008-04-21 | 2008-09-10 | 湖南有色凯铂生物药业有限公司 | 一种5-羟甲基噻唑的制备方法 |
CN101863853B (zh) * | 2009-12-28 | 2012-12-19 | 安徽贝克联合制药有限公司 | 一锅煮法制备5-羟甲基噻唑工艺 |
BR112020008124A2 (pt) | 2017-10-27 | 2020-10-06 | Syngenta Participations Ag | composições de controle de vetores, métodos e produtos utilizando as mesmas |
CN116375662B (zh) * | 2022-12-30 | 2024-07-23 | 新沂市砥研医药技术研究院有限公司 | 一种高效的5-羟甲基噻唑医药中间体的纯化工艺 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4247464A (en) * | 1979-10-01 | 1981-01-27 | General Electric Company | Liquid extraction method for recovering aromatic bisimides |
DE3631538A1 (de) * | 1986-09-17 | 1988-03-24 | Bayer Ag | Verfahren zur herstellung von 2-chlor-5-chlormethylthiazol |
JPS63165334A (ja) * | 1986-12-27 | 1988-07-08 | Hodogaya Chem Co Ltd | 2,6−ジクロロベンジルアルコ−ルの製造法 |
IE913840A1 (en) * | 1990-11-20 | 1992-05-20 | Abbott Lab | Retroviral protease inhibiting compounds |
DE69334250D1 (de) * | 1992-12-29 | 2009-01-29 | Abbott Lab | Verfahren und Intermediate zur Herstellung von retroviralen Proteasehemmern |
-
1995
- 1995-11-15 PT PT95940008T patent/PT793659E/pt unknown
- 1995-11-15 MX MX9703766A patent/MX9703766A/es unknown
- 1995-11-15 DE DE69520368T patent/DE69520368T2/de not_active Expired - Fee Related
- 1995-11-15 AT AT95940008T patent/ATE199714T1/de not_active IP Right Cessation
- 1995-11-15 WO PCT/US1995/014930 patent/WO1996016050A1/en active IP Right Grant
- 1995-11-15 DK DK95940008T patent/DK0793659T3/da active
- 1995-11-15 EP EP95940008A patent/EP0793659B1/en not_active Expired - Lifetime
- 1995-11-15 ES ES95940008T patent/ES2156955T3/es not_active Expired - Lifetime
- 1995-11-15 JP JP8516978A patent/JPH10509177A/ja not_active Ceased
-
1996
- 1996-05-22 US US08/651,439 patent/US5712400A/en not_active Expired - Fee Related
-
2001
- 2001-05-15 GR GR20010400716T patent/GR3035865T3/el not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
US5712400A (en) | 1998-01-27 |
EP0793659B1 (en) | 2001-03-14 |
DK0793659T3 (da) | 2001-06-11 |
ATE199714T1 (de) | 2001-03-15 |
ES2156955T3 (es) | 2001-08-01 |
JPH10509177A (ja) | 1998-09-08 |
DE69520368T2 (de) | 2001-06-28 |
GR3035865T3 (en) | 2001-08-31 |
PT793659E (pt) | 2001-07-31 |
WO1996016050A1 (en) | 1996-05-30 |
DE69520368D1 (de) | 2001-04-19 |
EP0793659A1 (en) | 1997-09-10 |
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