ES2038218T3 - Un procedimiento para preparar nuevos derivados de 2-alquilsulfinil-4(3h)-quinazolinona. - Google Patents
Un procedimiento para preparar nuevos derivados de 2-alquilsulfinil-4(3h)-quinazolinona.Info
- Publication number
- ES2038218T3 ES2038218T3 ES198888101149T ES88101149T ES2038218T3 ES 2038218 T3 ES2038218 T3 ES 2038218T3 ES 198888101149 T ES198888101149 T ES 198888101149T ES 88101149 T ES88101149 T ES 88101149T ES 2038218 T3 ES2038218 T3 ES 2038218T3
- Authority
- ES
- Spain
- Prior art keywords
- alkylsulfinyl
- group
- quinazolinone
- procedure
- new derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/95—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in positions 2 and 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
LA INVENCION SE REFIERE A DERIVADOS DE 2-ALQUILSULFINIL-4(3H) QIONAZOLINONA DE FORMULA (I) EN LA QUE R1 ES UN GRUPO ALQUILO DE 1 A 6 C, ARILO. ARILO SUSTITUIDO O ARALQUILO; R2 ES UN GRUPO FENILO, FENILO SUSTITUIDO O UN GRUPO HETEROCICLICO DE 5 O 6 MIEMBROS QUE CONTIENE UNO O MAS ATOMOS DE N, O O S COMO HETEROATOMOS Y QUE PUEDE ESTAR SUSTITUIDO O CONDENSADO CON UN ANILLO BENCENICO, N ES 1 O 2, Y X ES HIDROGENO, UN GRUPO ALQUILO DE 1 A 6 C O UN ATOMO DE HALOGENO. TAMBIEN SE REFIERE LA INVENCION A LAS SALES DE ADICION DE ACIDO FARMACEUTICAMENTE ACEPTABLES. LOS COMPUESTOS DE LA INVENCION SON UTILES COMO AGENTES ANTIULCERAS.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2012487 | 1987-01-30 | ||
JP62205072A JPH0749423B2 (ja) | 1987-01-30 | 1987-08-20 | 2−アルキルスルフイニル−4(3h)−キナゾリノン誘導体、その製造方法およびそれを有効成分とする抗潰瘍薬 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2038218T3 true ES2038218T3 (es) | 1993-07-16 |
Family
ID=26357021
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES198888101149T Expired - Lifetime ES2038218T3 (es) | 1987-01-30 | 1988-01-27 | Un procedimiento para preparar nuevos derivados de 2-alquilsulfinil-4(3h)-quinazolinona. |
Country Status (6)
Country | Link |
---|---|
US (1) | US4833144A (es) |
EP (1) | EP0276826B1 (es) |
JP (1) | JPH0749423B2 (es) |
KR (1) | KR960012367B1 (es) |
DE (1) | DE3867075D1 (es) |
ES (1) | ES2038218T3 (es) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2008113881A1 (es) * | 2007-03-22 | 2008-09-25 | Consejo Superior De Investigaciones Científicas | Compuesto inhibidor dual de las enzimas pde7 y/o pde4, composiciones farmaceúticas y sus aplicaciones |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH07107056B2 (ja) * | 1987-01-30 | 1995-11-15 | 日清製粉株式会社 | 4(3h)−キナゾリノン誘導体、その製造方法およびそれを有効成分とする抗潰瘍剤 |
US5283247A (en) * | 1991-02-06 | 1994-02-01 | Research Corporation Technologies, Inc. | Anticonvulsant substituted quinazolones |
EP0698013B1 (en) * | 1993-05-12 | 2001-10-04 | E.I. Du Pont De Nemours And Company | Fungicidal fused bicyclic pyrimidinones |
US6255311B1 (en) * | 1998-01-14 | 2001-07-03 | E. I. Du Pont De Nemours And Company | Fungicidal fused bicyclic pyrimidinones |
CN101225083A (zh) | 2007-01-16 | 2008-07-23 | 北京摩力克科技有限公司 | 四氢喹唑啉酮类化合物及其用于制备治疗和预防病毒性疾病的药物的用途 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE225131C (es) * | ||||
DD225131A1 (de) * | 1984-01-30 | 1985-07-24 | Akad Wissenschaften Ddr | Verfahren zur herstellung 2-substituierter 3,4-dihydrochinazolin-4-one |
US4576941A (en) * | 1984-02-29 | 1986-03-18 | Usv Pharmaceutical Corp. | Compounds for treating hypertension |
US4605657A (en) * | 1985-04-30 | 1986-08-12 | Chevron Research Company | 4-quinazalone fungicides |
-
1987
- 1987-08-20 JP JP62205072A patent/JPH0749423B2/ja not_active Expired - Fee Related
-
1988
- 1988-01-26 US US07/148,602 patent/US4833144A/en not_active Expired - Lifetime
- 1988-01-27 EP EP88101149A patent/EP0276826B1/en not_active Expired - Lifetime
- 1988-01-27 DE DE8888101149T patent/DE3867075D1/de not_active Expired - Fee Related
- 1988-01-27 ES ES198888101149T patent/ES2038218T3/es not_active Expired - Lifetime
- 1988-01-29 KR KR1019880000741A patent/KR960012367B1/ko not_active IP Right Cessation
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2008113881A1 (es) * | 2007-03-22 | 2008-09-25 | Consejo Superior De Investigaciones Científicas | Compuesto inhibidor dual de las enzimas pde7 y/o pde4, composiciones farmaceúticas y sus aplicaciones |
ES2308916A1 (es) * | 2007-03-22 | 2008-12-01 | Consejo Superior De Investigaciones Cientificas | Compuesto inhibidor dual de las enzimas pde7 y/o pde4, composiciones farmaceuticas y sus aplicaciones. |
Also Published As
Publication number | Publication date |
---|---|
JPH0749423B2 (ja) | 1995-05-31 |
EP0276826B1 (en) | 1991-12-27 |
JPS63301873A (ja) | 1988-12-08 |
KR960012367B1 (ko) | 1996-09-20 |
EP0276826A1 (en) | 1988-08-03 |
KR880008995A (ko) | 1988-09-13 |
US4833144A (en) | 1989-05-23 |
DE3867075D1 (de) | 1992-02-06 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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