ES2001440A6 - Procedimiento de prepararion de nuevos derivados de catecol - Google Patents

Procedimiento de prepararion de nuevos derivados de catecol

Info

Publication number
ES2001440A6
ES2001440A6 ES8602155A ES8602155A ES2001440A6 ES 2001440 A6 ES2001440 A6 ES 2001440A6 ES 8602155 A ES8602155 A ES 8602155A ES 8602155 A ES8602155 A ES 8602155A ES 2001440 A6 ES2001440 A6 ES 2001440A6
Authority
ES
Spain
Prior art keywords
same
image
preparation
catechol derivatives
compositions containing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES8602155A
Other languages
English (en)
Inventor
Michel Follet
Marc Bonato
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ipsen Pharma SAS
Original Assignee
Societe de Conseils de Recherches et dApplications Scientifiques SCRAS SAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Societe de Conseils de Recherches et dApplications Scientifiques SCRAS SAS filed Critical Societe de Conseils de Recherches et dApplications Scientifiques SCRAS SAS
Publication of ES2001440A6 publication Critical patent/ES2001440A6/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D335/00—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom
    • C07D335/04—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D335/06—Benzothiopyrans; Hydrogenated benzothiopyrans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/095—Sulfur, selenium, or tellurium compounds, e.g. thiols
    • A61K31/10—Sulfides; Sulfoxides; Sulfones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D337/00—Heterocyclic compounds containing rings of more than six members having one sulfur atom as the only ring hetero atom
    • C07D337/02—Seven-membered rings
    • C07D337/06—Seven-membered rings condensed with carbocyclic rings or ring systems
    • C07D337/08—Seven-membered rings condensed with carbocyclic rings or ring systems condensed with one six-membered ring

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Cardiology (AREA)
  • Immunology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Steroid Compounds (AREA)

Abstract

SE DESCRIBE UN PROCEDIMIENTO DE PREPARACION DE NUEVOS COMPUESTOS DE FORMULA GENERAL: EN LA QUE R REPRESENTA GRUPOS HIDROCARBONADOS ACICLICOS, ALICICLICOS Y AROMATICOS, QUE COMPRENDE HACER REACCIONAR S-(3,4-DIHIDROXIFENIL)-ISOTIOUREA DE FORMULA II CON UN TOSILATO DE FORMULA III DONDE R ES COMO ANTES. LOS COMPUESTOS OBTENIDOS SON UTILES COMO INHIBIDORES DE LA LIPOXIGENASA Y LA CICLOOXIGENASA.
ES8602155A 1985-09-26 1986-09-25 Procedimiento de prepararion de nuevos derivados de catecol Expired ES2001440A6 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB858523776A GB8523776D0 (en) 1985-09-26 1985-09-26 Catechol derivatives

Publications (1)

Publication Number Publication Date
ES2001440A6 true ES2001440A6 (es) 1988-05-16

Family

ID=10585770

Family Applications (2)

Application Number Title Priority Date Filing Date
ES8602173A Expired ES2001705A6 (es) 1985-09-26 1986-09-25 Procedimiento de preparacion de nuevos derivados de catecol biciclicos
ES8602155A Expired ES2001440A6 (es) 1985-09-26 1986-09-25 Procedimiento de prepararion de nuevos derivados de catecol

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES8602173A Expired ES2001705A6 (es) 1985-09-26 1986-09-25 Procedimiento de preparacion de nuevos derivados de catecol biciclicos

Country Status (28)

Country Link
US (2) US4699919A (es)
JP (2) JPS6284055A (es)
AR (2) AR242559A1 (es)
AT (2) AT396469B (es)
BE (2) BE905432A (es)
CA (2) CA1278299C (es)
CH (2) CH668421A5 (es)
DE (2) DE3632824A1 (es)
DK (2) DK168334B1 (es)
DZ (2) DZ991A1 (es)
ES (2) ES2001705A6 (es)
FI (2) FI87646C (es)
FR (4) FR2587699B1 (es)
GB (3) GB8523776D0 (es)
HK (2) HK91289A (es)
IE (2) IE59479B1 (es)
IT (2) IT1235760B (es)
LU (2) LU86591A1 (es)
MA (2) MA20780A1 (es)
MY (2) MY103521A (es)
NL (2) NL189334C (es)
NO (2) NO165238C (es)
OA (2) OA08417A (es)
PT (2) PT83436B (es)
SE (2) SE467053B (es)
SG (1) SG65889G (es)
TN (2) TNSN86134A1 (es)
ZA (2) ZA866906B (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4927629A (en) * 1987-12-17 1990-05-22 Huntington Medical Research Institutes Relaxation of smooth vascular muscle
WO1999024038A1 (en) 1997-11-07 1999-05-20 Johns Hopkins University Methods for treatment of disorders of cardiac contractility
CN102159203A (zh) * 2008-07-23 2011-08-17 麻省理工学院 组蛋白脱乙酰酶1(hdac1)的活化防范dna损伤和增加神经元存活
US9115053B2 (en) 2011-07-22 2015-08-25 Massachusetts Institute Of Technology Activators of class I histone deacetlyases (HDACS) and uses thereof

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2549118A (en) * 1949-10-05 1951-04-17 Us Rubber Co Vulcanized rubber and method of preserving same
CH301691A (de) * 1951-08-07 1954-09-15 Cilag Ag Verfahren zur Herstellung eines neuen aromatischen Thioäthers.
CH301687A (de) * 1951-08-07 1954-09-15 Cilag Ag Verfahren zur Herstellung eines neuen aromatischen Thioäthers.
CH301688A (de) * 1951-08-07 1954-09-15 Cilag Ag Verfahren zur Herstellung eines neuen aromatischen Thioäthers.
US3148997A (en) * 1963-01-04 1964-09-15 Dow Chemical Co Catechol compounds in improving clays and clay-containing materials
US3274257A (en) * 1963-06-17 1966-09-20 Dow Chemical Co Synthesis of (alkylthio) phenols
US3282979A (en) * 1963-06-17 1966-11-01 Dow Chemical Co Phenolic thioethers
GB1362782A (en) * 1970-08-26 1974-08-07 Fisons Ltd Tetrazole derivatives
US3751483A (en) * 1971-10-13 1973-08-07 Crown Zellerbach Corp Phenolic thioethers and process for preparing same
GB1428110A (en) * 1972-05-30 1976-03-17 Reckitt & Colmann Prod Ltd Pharmaceutical antihypertensive and vasodilator compositions
JPS506340A (es) * 1973-05-16 1975-01-23
DE2644591A1 (de) * 1976-10-02 1978-04-06 Bayer Ag Verfahren zur herstellung von arylsulfoniumsalzen
AU548253B2 (en) * 1981-05-11 1985-12-05 Pierre Fabre S.A. Benzoxepine derivatives and sulphur and nitrogen analogues thereof
US4661505A (en) * 1982-11-03 1987-04-28 Eli Lilly And Company Leukotriene antagonists
JPS60260532A (ja) * 1984-06-07 1985-12-23 Yamanouchi Pharmaceut Co Ltd 新規カテコ−ル誘導体
US4785004A (en) * 1985-12-23 1988-11-15 Ciba-Geigy Corporation Aromatic thioethers

Also Published As

Publication number Publication date
US4699919A (en) 1987-10-13
SE8603792D0 (sv) 1986-09-10
DK165115C (da) 1993-03-01
OA08417A (fr) 1988-06-30
PT83437A (en) 1986-10-01
IE59479B1 (en) 1994-03-09
DE3632824C2 (es) 1992-04-30
PT83436A (en) 1986-10-01
NO863834D0 (no) 1986-09-25
MY103521A (en) 1993-07-31
DK457486D0 (da) 1986-09-25
FI863743A0 (fi) 1986-09-16
GB2181431A (en) 1987-04-23
DE3632841A1 (de) 1987-04-02
IT1235760B (it) 1992-09-28
ATA257386A (de) 1993-01-15
CH668421A5 (fr) 1988-12-30
FR2587703B1 (fr) 1988-11-04
SE8603792L (sv) 1987-03-27
NL8602382A (nl) 1987-04-16
NL189410C (nl) 1993-04-01
FR2587698B1 (fr) 1989-04-28
NL8602383A (nl) 1987-04-16
NO165238C (no) 1991-01-16
JPH0482129B2 (es) 1992-12-25
TNSN86135A1 (fr) 1990-01-01
GB2189782B (en) 1989-04-12
GB2189782A (en) 1987-11-04
IE59478B1 (en) 1994-03-09
GB2181431B (en) 1989-09-20
PT83436B (pt) 1988-07-29
NO165238B (no) 1990-10-08
FR2587703A1 (fr) 1987-03-27
LU86591A1 (fr) 1987-01-22
PT83437B (pt) 1988-07-29
CA1318686C (en) 1993-06-01
DE3632841C2 (es) 1992-06-11
MA20780A1 (fr) 1987-04-01
SE8603793L (sv) 1987-03-27
DK168334B1 (da) 1994-03-14
FI87646B (fi) 1992-10-30
DK165115B (da) 1992-10-12
IT1235761B (it) 1992-09-28
FI863742A (fi) 1987-03-27
MA20779A1 (fr) 1987-04-01
IT8621837A0 (it) 1986-09-26
JPH0417956B2 (es) 1992-03-26
NO863834L (no) 1987-03-27
DZ991A1 (fr) 2004-09-13
FR2587702A1 (fr) 1987-03-27
NO863835D0 (no) 1986-09-25
MY105863A (en) 1995-02-28
GB8623075D0 (en) 1986-10-29
FI87646C (fi) 1993-02-10
US5013756A (en) 1991-05-07
FI84480B (fi) 1991-08-30
SE464522B (sv) 1991-05-06
FI863743A (fi) 1987-03-27
IT8621836A0 (it) 1986-09-26
IE862533L (en) 1987-03-26
DK457386A (da) 1987-03-27
DK457486A (da) 1987-03-27
AR242559A1 (es) 1993-04-30
FR2587702B1 (fr) 1988-11-04
GB8523776D0 (en) 1985-10-30
NO863835L (no) 1987-03-27
BE905432A (fr) 1987-03-16
HK91289A (en) 1989-11-24
ES2001705A6 (es) 1988-06-01
CA1278299C (en) 1990-12-27
JPS6284080A (ja) 1987-04-17
IE862532L (en) 1987-03-26
FR2587699B1 (fr) 1988-11-10
AT396469B (de) 1993-09-27
FI863742A0 (fi) 1986-09-16
NO170415B (no) 1992-07-06
OA08416A (fr) 1988-06-30
FR2587698A1 (fr) 1987-03-27
FR2587699A1 (fr) 1987-03-27
GB8623074D0 (en) 1986-10-29
ZA866905B (en) 1987-04-29
NL189334C (nl) 1993-03-16
ATA257486A (de) 1996-06-15
BE905433A (fr) 1987-03-16
FI84480C (fi) 1991-12-10
DZ990A1 (fr) 2004-09-13
SG65889G (en) 1990-01-26
ZA866906B (en) 1987-04-29
DE3632824A1 (de) 1987-04-02
AR241702A1 (es) 1992-11-30
NO170415C (no) 1992-10-14
LU86590A1 (fr) 1987-01-22
HK46190A (en) 1990-06-22
TNSN86134A1 (fr) 1990-01-01
NL189410B (nl) 1992-11-02
CH668261A5 (fr) 1988-12-15
DK457386D0 (da) 1986-09-25
SE8603793D0 (sv) 1986-09-10
JPS6284055A (ja) 1987-04-17
SE467053B (sv) 1992-05-18
AT402070B (de) 1997-01-27

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Legal Events

Date Code Title Description
SA6 Expiration date (snapshot 920101)

Free format text: 2006-09-25

FD1A Patent lapsed

Effective date: 20001204