EE200200529A - Tsüklilised ß-aminohappe derivaadid kui maatriksmetalloproteaaside ja TNF-a inhibiitorid - Google Patents
Tsüklilised ß-aminohappe derivaadid kui maatriksmetalloproteaaside ja TNF-a inhibiitoridInfo
- Publication number
- EE200200529A EE200200529A EEP200200529A EEP200200529A EE200200529A EE 200200529 A EE200200529 A EE 200200529A EE P200200529 A EEP200200529 A EE P200200529A EE P200200529 A EEP200200529 A EE P200200529A EE 200200529 A EE200200529 A EE 200200529A
- Authority
- EE
- Estonia
- Prior art keywords
- tnf
- inhibitors
- cyclic
- amino acid
- acid derivatives
- Prior art date
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- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
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- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
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- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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- C07C259/04—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids
- C07C259/08—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids having carbon atoms of hydroxamic groups bound to carbon atoms of rings other than six-membered aromatic rings
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- C07D—HETEROCYCLIC COMPOUNDS
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- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
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- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
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- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
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- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
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- C—CHEMISTRY; METALLURGY
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- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
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- C—CHEMISTRY; METALLURGY
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- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
- C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US19018200P | 2000-03-17 | 2000-03-17 | |
US23337300P | 2000-09-18 | 2000-09-18 | |
US25553900P | 2000-12-14 | 2000-12-14 | |
PCT/US2001/008334 WO2001070673A2 (en) | 2000-03-17 | 2001-03-15 | CYCLIC β-AMINO ACID DERIVATIVES AS INHIBITORS OF MATRIX METALLOPROTEASES AND TNF-$g(a) |
Publications (1)
Publication Number | Publication Date |
---|---|
EE200200529A true EE200200529A (et) | 2004-02-16 |
Family
ID=27392700
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EEP200200529A EE200200529A (et) | 2000-03-17 | 2001-03-15 | Tsüklilised ß-aminohappe derivaadid kui maatriksmetalloproteaaside ja TNF-a inhibiitorid |
Country Status (20)
Country | Link |
---|---|
US (2) | US6743807B2 (et) |
EP (1) | EP1263755A2 (et) |
JP (1) | JP2003528072A (et) |
KR (1) | KR20030009391A (et) |
CN (1) | CN1481377A (et) |
AR (1) | AR035710A1 (et) |
AU (1) | AU2001250849A1 (et) |
BR (1) | BR0109467A (et) |
CA (1) | CA2401870A1 (et) |
CZ (1) | CZ20023033A3 (et) |
EE (1) | EE200200529A (et) |
HK (1) | HK1049165A1 (et) |
HU (1) | HUP0300850A2 (et) |
IL (1) | IL151552A0 (et) |
MX (1) | MXPA02009020A (et) |
NO (1) | NO20024402D0 (et) |
NZ (1) | NZ521248A (et) |
PL (1) | PL360678A1 (et) |
SK (1) | SK13072002A3 (et) |
WO (1) | WO2001070673A2 (et) |
Families Citing this family (60)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK1235830T3 (da) | 1999-12-10 | 2004-03-29 | Pfizer Prod Inc | Pyrrolo[2,3-d]pyrimidin-forbindelser som proteinkinaseinhibitorer |
CA2439539A1 (en) * | 2001-03-15 | 2002-09-26 | Matthew E. Voss | Spiro-cyclic beta-amino acid derivatives as inhibitors of matrix metalloproteinases and tnf-alpha converting enzyme (tage) |
GB0112836D0 (en) | 2001-05-25 | 2001-07-18 | Smithkline Beecham Plc | Medicaments |
GB0112834D0 (en) | 2001-05-25 | 2001-07-18 | Smithkline Beecham Plc | Medicaments |
US7186855B2 (en) | 2001-06-11 | 2007-03-06 | Xenoport, Inc. | Prodrugs of GABA analogs, compositions and uses thereof |
US8048917B2 (en) | 2005-04-06 | 2011-11-01 | Xenoport, Inc. | Prodrugs of GABA analogs, compositions and uses thereof |
US6818787B2 (en) | 2001-06-11 | 2004-11-16 | Xenoport, Inc. | Prodrugs of GABA analogs, compositions and uses thereof |
EP1427408A4 (en) | 2001-09-17 | 2005-10-26 | Bristol Myers Squibb Co | CYCLIC HYDROXAMINE ACIDS AS INHIBITORS OF MATRIX METALLOPROTEINASES AND / OR TNF-a-CONVERTASE (TACE TNF-a-CONVERTING ENZYM) |
AR040336A1 (es) | 2002-06-26 | 2005-03-30 | Glaxo Group Ltd | Compuesto de piperidina, uso del mismo para la fabricacion de un medicamento, composicion farmaceutica que lo comprende y procedimiento para preparar dicho compuesto |
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-
2001
- 2001-03-15 AU AU2001250849A patent/AU2001250849A1/en not_active Abandoned
- 2001-03-15 KR KR1020027012253A patent/KR20030009391A/ko not_active Application Discontinuation
- 2001-03-15 PL PL36067801A patent/PL360678A1/xx not_active Application Discontinuation
- 2001-03-15 EP EP01924170A patent/EP1263755A2/en not_active Withdrawn
- 2001-03-15 WO PCT/US2001/008334 patent/WO2001070673A2/en not_active Application Discontinuation
- 2001-03-15 HU HU0300850A patent/HUP0300850A2/hu unknown
- 2001-03-15 CZ CZ20023033A patent/CZ20023033A3/cs unknown
- 2001-03-15 CA CA002401870A patent/CA2401870A1/en not_active Abandoned
- 2001-03-15 MX MXPA02009020A patent/MXPA02009020A/es unknown
- 2001-03-15 BR BR0109467-0A patent/BR0109467A/pt not_active Application Discontinuation
- 2001-03-15 SK SK1307-2002A patent/SK13072002A3/sk unknown
- 2001-03-15 CN CNA018094090A patent/CN1481377A/zh active Pending
- 2001-03-15 NZ NZ521248A patent/NZ521248A/en unknown
- 2001-03-15 IL IL15155201A patent/IL151552A0/xx unknown
- 2001-03-15 EE EEP200200529A patent/EE200200529A/et unknown
- 2001-03-15 JP JP2001568885A patent/JP2003528072A/ja active Pending
- 2001-03-16 US US09/811,233 patent/US6743807B2/en not_active Expired - Lifetime
- 2001-03-16 AR ARP010101254A patent/AR035710A1/es unknown
-
2002
- 2002-09-13 NO NO20024402A patent/NO20024402D0/no unknown
-
2003
- 2003-02-21 HK HK03101351.8A patent/HK1049165A1/zh unknown
-
2004
- 2004-02-13 US US10/779,539 patent/US6984648B2/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
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HK1049165A1 (zh) | 2003-05-02 |
JP2003528072A (ja) | 2003-09-24 |
MXPA02009020A (es) | 2003-02-12 |
SK13072002A3 (sk) | 2003-08-05 |
AU2001250849A1 (en) | 2001-10-03 |
WO2001070673A3 (en) | 2002-03-14 |
US6984648B2 (en) | 2006-01-10 |
BR0109467A (pt) | 2003-06-03 |
EP1263755A2 (en) | 2002-12-11 |
CZ20023033A3 (cs) | 2003-01-15 |
KR20030009391A (ko) | 2003-01-29 |
NO20024402D0 (no) | 2002-09-13 |
IL151552A0 (en) | 2003-04-10 |
US20040162426A1 (en) | 2004-08-19 |
CN1481377A (zh) | 2004-03-10 |
US6743807B2 (en) | 2004-06-01 |
WO2001070673A2 (en) | 2001-09-27 |
US20020016336A1 (en) | 2002-02-07 |
AR035710A1 (es) | 2004-07-07 |
HUP0300850A2 (hu) | 2003-07-28 |
PL360678A1 (en) | 2004-09-20 |
NZ521248A (en) | 2004-04-30 |
CA2401870A1 (en) | 2001-09-27 |
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