US6407132B1
(en)
*
|
1997-07-25 |
2002-06-18 |
James Black Foundation Limited |
Substituted imidazole derivatives and their use as histamine H3 receptor ligands
|
GB9718913D0
(en)
*
|
1997-09-05 |
1997-11-12 |
Glaxo Group Ltd |
Substituted oxindole derivatives
|
DE19816624A1
(de)
*
|
1998-04-15 |
1999-10-21 |
Boehringer Ingelheim Pharma |
Neue substituierte Indolinone, ihre Herstellung und ihre Verwendung als Arzneimittel
|
US6319918B1
(en)
|
1998-06-04 |
2001-11-20 |
Boehringer Ingelheim Pharma Kg |
Substituted indolinones with kinase inhibitory activity
|
DE19824922A1
(de)
*
|
1998-06-04 |
1999-12-09 |
Boehringer Ingelheim Pharma |
Neue substituierte Indolinone, ihre Herstellung und ihre Verwendung als Arzneimittel
|
WO2000035920A2
(en)
*
|
1998-12-17 |
2000-06-22 |
F. Hoffmann-La Roche Ag |
4,5-azolo-oxindoles
|
EP1149093A1
(en)
|
1998-12-17 |
2001-10-31 |
F. Hoffmann-La Roche Ag |
4-aryloxindoles as inhibitors of jnk protein kinases
|
ATE387448T1
(de)
*
|
1998-12-17 |
2008-03-15 |
Hoffmann La Roche |
4,5-pyrazinoxindole als proteinkinasehemmer
|
BR9916327A
(pt)
|
1998-12-17 |
2001-09-18 |
Hoffmann La Roche |
Oxindóis de 4-alquenila (e alquinila) como inibidores de cinases dependentes de ciclina, em particular, cdk2
|
US6153634A
(en)
*
|
1998-12-17 |
2000-11-28 |
Hoffmann-La Roche Inc. |
4,5-azolo-oxindoles
|
BR0007532A
(pt)
|
1999-01-13 |
2001-11-20 |
Univ New York State Res Found |
Métodos para identificar inibidores de proteìnaquinase, para testar compostos para umacapacidade de inibir a atividade de proteìnaquinase e para inibir uma proteìna quinase, inibidorde proteìna tirosina quinase não peptìdica, e,método de tratar uma condição responsiva a uminibidor de proteìna quinase em um paciente
|
US6492398B1
(en)
*
|
1999-03-04 |
2002-12-10 |
Smithkline Beechman Corporation |
Thiazoloindolinone compounds
|
GB9904932D0
(en)
*
|
1999-03-04 |
1999-04-28 |
Glaxo Group Ltd |
Composition and method for preventing/reducing the severity of side effects of chemotherapy and/or radiation therapy
|
GB9904933D0
(en)
|
1999-03-04 |
1999-04-28 |
Glaxo Group Ltd |
Compounds
|
GB9904930D0
(en)
*
|
1999-03-04 |
1999-04-28 |
Glaxo Group Ltd |
Thiazoloindolinone compounds
|
US6624171B1
(en)
|
1999-03-04 |
2003-09-23 |
Smithkline Beecham Corporation |
Substituted aza-oxindole derivatives
|
US6339098B1
(en)
|
1999-05-04 |
2002-01-15 |
American Home Products Corporation |
2,1-benzisothiazoline 2,2-dioxides
|
US6358947B1
(en)
|
1999-05-04 |
2002-03-19 |
American Home Products Corporation |
Tetracyclic progesterone receptor modulator compounds and methods
|
US6417214B1
(en)
|
1999-05-04 |
2002-07-09 |
Wyeth |
3,3-substituted indoline derivatives
|
US6306851B1
(en)
|
1999-05-04 |
2001-10-23 |
American Home Products Corporation |
Cyclocarbamate and cyclic amide derivatives
|
US6399593B1
(en)
|
1999-05-04 |
2002-06-04 |
Wyeth |
Cyclic regimens using cyclic urea and cyclic amide derivatives
|
US6462032B1
(en)
|
1999-05-04 |
2002-10-08 |
Wyeth |
Cyclic regimens utilizing indoline derivatives
|
US6407101B1
(en)
|
1999-05-04 |
2002-06-18 |
American Home Products Corporation |
Cyanopyrroles
|
US6329416B1
(en)
|
1999-05-04 |
2001-12-11 |
American Home Products Corporation |
Combination regimens using 3,3-substituted indoline derivatives
|
US6509334B1
(en)
|
1999-05-04 |
2003-01-21 |
American Home Products Corporation |
Cyclocarbamate derivatives as progesterone receptor modulators
|
US6423699B1
(en)
|
1999-05-04 |
2002-07-23 |
American Home Products Corporation |
Combination therapies using benzimidazolones
|
US6391907B1
(en)
*
|
1999-05-04 |
2002-05-21 |
American Home Products Corporation |
Indoline derivatives
|
US6498154B1
(en)
|
1999-05-04 |
2002-12-24 |
Wyeth |
Cyclic regimens using quinazolinone and benzoxazine derivatives
|
US6380178B1
(en)
|
1999-05-04 |
2002-04-30 |
American Home Products Corporation |
Cyclic regimens using cyclocarbamate and cyclic amide derivatives
|
US6380235B1
(en)
|
1999-05-04 |
2002-04-30 |
American Home Products Corporation |
Benzimidazolones and analogues
|
US6444668B1
(en)
|
1999-05-04 |
2002-09-03 |
Wyeth |
Combination regimens using progesterone receptor modulators
|
US6355648B1
(en)
|
1999-05-04 |
2002-03-12 |
American Home Products Corporation |
Thio-oxindole derivatives
|
US6358948B1
(en)
|
1999-05-04 |
2002-03-19 |
American Home Products Corporation |
Quinazolinone and benzoxazine derivatives as progesterone receptor modulators
|
US6369056B1
(en)
|
1999-05-04 |
2002-04-09 |
American Home Products Corporation |
Cyclic urea and cyclic amide derivatives
|
US6319912B1
(en)
|
1999-05-04 |
2001-11-20 |
American Home Products Corporation |
Cyclic regimens using 2,1-benzisothiazoline 2,2-dioxides
|
GB9911053D0
(en)
|
1999-05-12 |
1999-07-14 |
Pharmacia & Upjohn Spa |
4,5,6,7-tetrahydroindazole derivatives process for their preparation and their use as antitumour agents
|
DE19924401A1
(de)
*
|
1999-05-27 |
2000-11-30 |
Boehringer Ingelheim Pharma |
Neue substituierte Indolinone, ihre Herstellung und ihre Verwendung als Arzneimittel
|
ES2257313T3
(es)
*
|
1999-08-27 |
2006-08-01 |
BOEHRINGER INGELHEIM PHARMA GMBH & CO.KG |
Indolinonas sustituidas en calidad de inhibidores de tirosina quinasa.
|
US6552008B1
(en)
*
|
1999-09-24 |
2003-04-22 |
Smithkline Beecham Corporation |
Thrombopoietin mimetics
|
US6762180B1
(en)
|
1999-10-13 |
2004-07-13 |
Boehringer Ingelheim Pharma Kg |
Substituted indolines which inhibit receptor tyrosine kinases
|
DE19949209A1
(de)
*
|
1999-10-13 |
2001-04-19 |
Boehringer Ingelheim Pharma |
In 5-Stellung substituierte Indolinone, ihre Herstellung und ihre Verwendung als Arzneimittel
|
UA75054C2
(uk)
*
|
1999-10-13 |
2006-03-15 |
Бьорінгер Інгельхайм Фарма Гмбх & Ко. Кг |
Заміщені в положенні 6 індолінони, їх одержання та їх застосування як лікарського засобу
|
US6313310B1
(en)
|
1999-12-15 |
2001-11-06 |
Hoffmann-La Roche Inc. |
4-and 5-alkynyloxindoles and 4-and 5-alkenyloxindoles
|
YU54202A
(sh)
|
2000-01-18 |
2006-01-16 |
Agouron Pharmaceuticals Inc. |
Jedinjenja indazola, farmaceutske smeše i postupci za stimulisanje i inhibiranje ćelijske proliferacije
|
HN2001000008A
(es)
|
2000-01-21 |
2003-12-11 |
Inc Agouron Pharmaceuticals |
Compuesto de amida y composiciones farmaceuticas para inhibir proteinquinasas, y su modo de empleo
|
EP1207864A2
(en)
*
|
2000-02-05 |
2002-05-29 |
Vertex Pharmaceuticals Incorporated |
Compositions useful as inhibitors of erk
|
US6620818B1
(en)
|
2000-03-01 |
2003-09-16 |
Smithkline Beecham Corporation |
Method for reducing the severity of side effects of chemotherapy and/or radiation therapy
|
EP1274706A1
(en)
|
2000-04-18 |
2003-01-15 |
Agouron Pharmaceuticals, Inc. |
Pyrazoles for inhibiting protein kinases
|
UA73119C2
(en)
|
2000-04-19 |
2005-06-15 |
American Home Products Corpoir |
Derivatives of cyclic thiocarbamates, pharmaceutical composition including noted derivatives of cyclic thiocarbamates and active ingredients of medicines as modulators of progesterone receptors
|
US6534531B2
(en)
*
|
2000-04-27 |
2003-03-18 |
Bristol-Myers Squibb Company |
Methods for preventing and treating alopecia induced by chemotherapy or radiotherapy
|
WO2001082967A1
(en)
*
|
2000-04-28 |
2001-11-08 |
Yamanouchi Pharmaceutical Co., Ltd. |
MEDICINAL COMPOSITIONS FOR SUPPRESSING β-AMYLOID PRODUCTION
|
CY2010012I2
(el)
|
2000-05-25 |
2020-05-29 |
Novartis Ag |
Μιμητικα θρομβοποιητινης
|
GB0016454D0
(en)
|
2000-07-04 |
2000-08-23 |
Hoffmann La Roche |
Thienopyrrolidinones
|
AU2001277285A1
(en)
|
2000-08-09 |
2002-02-18 |
Agouron Pharmaceuticals, Inc. |
Pyrazole-thiazole compounds, pharmaceutical compositions containing them, and methods of their use for inhibiting cyclin-dependent kinases
|
ATE295354T1
(de)
|
2000-08-18 |
2005-05-15 |
Agouron Pharma |
Heterozyklische-hydroximino-fluorene und ihre verwendung zur inhibierung von proteinkinasen
|
WO2002020513A1
(en)
*
|
2000-09-01 |
2002-03-14 |
Glaxo Group Limited |
Oxindole derivatives
|
WO2002020479A1
(en)
|
2000-09-01 |
2002-03-14 |
Glaxo Group Limited |
Substituted oxindole derivatives as tyrosine kinase inhibitors
|
ATE281455T1
(de)
|
2000-09-01 |
2004-11-15 |
Glaxo Group Ltd |
Oxindolderivate
|
EP1201765A3
(en)
*
|
2000-10-16 |
2003-08-27 |
Axxima Pharmaceuticals Aktiengesellschaft |
Cellular kinases involved in cytomegalovirus infection and their inhibition
|
US6638965B2
(en)
|
2000-11-01 |
2003-10-28 |
Boehringer Ingelheim Pharma Kg |
Substituted indolinones, preparation thereof and their use as pharmaceutical compositions
|
DE10054019A1
(de)
*
|
2000-11-01 |
2002-05-23 |
Boehringer Ingelheim Pharma |
Neue substituierte Indolinone, ihre Herstellung und ihre Verwendung als Arzneimittel
|
SE0101230L
(sv)
*
|
2001-04-06 |
2002-10-07 |
Innoventus Project Ab |
Ny användning av en tyrosinkinasinhibitor
|
DE10117204A1
(de)
|
2001-04-06 |
2002-10-10 |
Boehringer Ingelheim Pharma |
In 6-Stellung substituierte Indolinone, ihre Herstellung und ihre Verwendung als Arzneimittel
|
CA2448076A1
(en)
*
|
2001-05-24 |
2002-11-28 |
Masahiko Hayakawa |
3-quinoline-2-(1h)-ylideneindolin-2-one derivatives
|
JP2005500041A
(ja)
|
2001-06-29 |
2005-01-06 |
アブ サイエンス |
強力で選択的かつ非毒性のc−kit阻害剤
|
JP2004537542A
(ja)
|
2001-06-29 |
2004-12-16 |
アブ サイエンス |
炎症性腸疾患(ibd)を治療するための、チロシンキナーゼ阻害剤の使用
|
DE60212627T2
(de)
|
2001-06-29 |
2007-06-14 |
Ab Science |
Verwendung von Tyrosinkinase-Inhibitoren zur Behandlung von entzündlichen Krankheiten
|
EP1450775B1
(en)
*
|
2001-09-20 |
2008-03-12 |
AB Science |
C-kit inhibitors for treating bacterial infections
|
CA2461182A1
(en)
*
|
2001-09-20 |
2003-05-01 |
Ab Science |
Use of tyrosine kinase inhibitors for promoting hair growth
|
WO2003027102A1
(en)
*
|
2001-09-27 |
2003-04-03 |
Allergan, Inc. |
3-(arylamino)methylene-1, 3-dihydro-2h-indol-2-ones as kinase inhibitors
|
WO2003027109A1
(en)
*
|
2001-09-27 |
2003-04-03 |
Allergan, Inc. |
3-(heteroarylamino)methylene-1, 3-dihydro-2h-indol-2-ones as kinase inhibitors
|
WO2003033491A1
(fr)
*
|
2001-10-16 |
2003-04-24 |
Nippon Kayaku Kabushiki Kaisha |
Composition medicinale de prevention ou de soulagement d'effets secondaires chez les patients souffrant de cancer et composition anticancereuse medicinale
|
US7005445B2
(en)
|
2001-10-22 |
2006-02-28 |
The Research Foundation Of State University Of New York |
Protein kinase and phosphatase inhibitors and methods for designing them
|
WO2003035621A1
(en)
*
|
2001-10-22 |
2003-05-01 |
The Research Foundation Of State University Of New York |
Protein kinase and phosphatase inhibitors, methods for designing them, and methods of using them
|
US20030187026A1
(en)
|
2001-12-13 |
2003-10-02 |
Qun Li |
Kinase inhibitors
|
US6797825B2
(en)
|
2001-12-13 |
2004-09-28 |
Abbott Laboratories |
Protein kinase inhibitors
|
JPWO2003051883A1
(ja)
*
|
2001-12-18 |
2005-04-28 |
協和醗酵工業株式会社 |
インドール誘導体
|
EP1465869B1
(en)
|
2001-12-21 |
2013-05-15 |
Exelixis Patent Company LLC |
Modulators of lxr
|
US7482366B2
(en)
*
|
2001-12-21 |
2009-01-27 |
X-Ceptor Therapeutics, Inc. |
Modulators of LXR
|
TWI329105B
(en)
|
2002-02-01 |
2010-08-21 |
Rigel Pharmaceuticals Inc |
2,4-pyrimidinediamine compounds and their uses
|
FR2836914B1
(fr)
|
2002-03-11 |
2008-03-14 |
Aventis Pharma Sa |
Indazoles substitues, compositions les contenant, procede de fabrication et utilisation
|
JP2005523928A
(ja)
*
|
2002-04-30 |
2005-08-11 |
アルコン,インコーポレイテッド |
眼内圧の低下および緑内障性網膜症/眼神経障害の処置の両方のための独特の手段としての、結合組織増殖因子(ctgf)の活性および/または発現を調節するか、阻害するか、または調整する薬剤
|
TWI280128B
(en)
|
2002-05-22 |
2007-05-01 |
Smithkline Beecham Corp |
3'-[(2Z)-[1-(3,4- dimethylphenyl)-1,5-dihydro-3-methyl-5-oxo-4H-pyrazol-4-ylidene]hydrazino]-2'-hydroxy-[1,1'-biphenyl]-3-carboxylic acid bis-(monoethanolamine)
|
US7169936B2
(en)
|
2002-07-23 |
2007-01-30 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Indolinone derivatives substituted in the 6-position, their preparation and their use as medicaments
|
US7514468B2
(en)
|
2002-07-23 |
2009-04-07 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Indolinone derivatives substituted in the 6 position, the preparation thereof and their use as pharmaceutical compositions
|
DE10233500A1
(de)
*
|
2002-07-24 |
2004-02-19 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
3-Z-[1-(4-(N-((4-Methyl-piperazin-1-yl)-methylcarbonyl)-N-methyl-amino)-anilino)-1-phenyl-methylen]-6-methoxycarbonyl-2-indolinon-Monoethansulfonat und dessen Verwendung als Arzneimittel
|
US20040082615A1
(en)
*
|
2002-08-07 |
2004-04-29 |
Michael Konkel |
3-Imino-2-indolones for the treatement of depression and/or anxiety
|
AU2003259689A1
(en)
*
|
2002-08-07 |
2004-02-25 |
Synaptic Pharmaceutical Corporation |
3-imino-2-indolones for the treatment of depression and/or anxiety
|
GB0225873D0
(en)
*
|
2002-11-06 |
2002-12-11 |
Cyclacel Ltd |
Combination
|
AU2003284572A1
(en)
*
|
2002-11-22 |
2004-06-18 |
Yamanouchi Pharmaceutical Co., Ltd. |
2-oxoindoline derivatives
|
DE60311879T2
(de)
|
2002-12-23 |
2007-12-20 |
Astex Therapeutics Ltd., Cambridge |
Synthese und screening von liganden mit hilfe von röntgenkristallographie
|
CN102358738A
(zh)
|
2003-07-30 |
2012-02-22 |
里格尔药品股份有限公司 |
2,4-嘧啶二胺化合物及其预防和治疗自体免疫疾病的用途
|
TW200526638A
(en)
|
2003-10-22 |
2005-08-16 |
Smithkline Beecham Corp |
2-(3,4-dimethylphenyl)-4-{[2-hydroxy-3'-(1H-tetrazol-5-yl)biphenyl-3-yl]-hydrazono}-5-methyl-2,4-dihydropyrazol-3-one choline
|
GB0328180D0
(en)
*
|
2003-12-04 |
2004-01-07 |
Cyclacel Ltd |
Combination
|
DE102004012069A1
(de)
*
|
2004-03-12 |
2005-09-29 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Neue aryl-haltige 5-Acylindolinone, deren Herstellung und deren Verwendung als Arzneimittel
|
WO2005118551A2
(en)
*
|
2004-05-28 |
2005-12-15 |
Ligand Pharmaceuticals Inc. |
Thrombopoietin activity modulating compounds and methods
|
WO2006047344A1
(en)
*
|
2004-10-25 |
2006-05-04 |
Ligand Pharmaceuticals, Inc. |
Thrombopoietin activity modulating compounds and methods
|
GT200500321A
(es)
*
|
2004-11-09 |
2006-09-04 |
|
Compuestos y composiciones como inhibidores de proteina kinase.
|
EP1819330A1
(en)
|
2004-12-01 |
2007-08-22 |
Devgen N.V. |
5-carboxamido substitued thiazole derivatives that interact with ion channels, in particular with ion channels from the kv family
|
DK1941798T3
(da)
*
|
2004-12-17 |
2012-08-27 |
Devgen Nv |
Nematicide præparater
|
PE20060777A1
(es)
*
|
2004-12-24 |
2006-10-06 |
Boehringer Ingelheim Int |
Derivados de indolinona para el tratamiento o la prevencion de enfermedades fibroticas
|
US7662824B2
(en)
|
2005-03-18 |
2010-02-16 |
Janssen Pharmaceutica Nv |
Acylhydrazones as kinase modulators
|
WO2006119660A1
(en)
*
|
2005-05-11 |
2006-11-16 |
Givaudan Sa |
Encapsulation method
|
WO2006133426A2
(en)
|
2005-06-08 |
2006-12-14 |
Rigel Pharmaceuticals, Inc. |
Compositions and methods for inhibition of the jak pathway
|
US20070203161A1
(en)
|
2006-02-24 |
2007-08-30 |
Rigel Pharmaceuticals, Inc. |
Compositions and methods for inhibition of the jak pathway
|
WO2007008895A1
(en)
*
|
2005-07-13 |
2007-01-18 |
Allergan, Inc. |
Kinase inhibitors
|
EP1902024B1
(en)
*
|
2005-07-13 |
2013-04-17 |
Allergan, Inc. |
Kinase inhibitors
|
US7749530B2
(en)
|
2005-07-13 |
2010-07-06 |
Allergan, Inc. |
Kinase inhibitors
|
GB0523041D0
(en)
*
|
2005-11-11 |
2005-12-21 |
Cyclacel Ltd |
Combination
|
CA2642229C
(en)
|
2006-02-24 |
2015-05-12 |
Rigel Pharmaceuticals, Inc. |
Compositions and methods for inhibition of the jak pathway
|
US8987474B2
(en)
*
|
2006-04-07 |
2015-03-24 |
University Of South Florida |
Inhibition of Shp2/PTPN11 protein tyrosine phosphatase by NSC-87877, NSC-117199 and their analogs
|
US7838542B2
(en)
|
2006-06-29 |
2010-11-23 |
Kinex Pharmaceuticals, Llc |
Bicyclic compositions and methods for modulating a kinase cascade
|
US8217177B2
(en)
*
|
2006-07-14 |
2012-07-10 |
Amgen Inc. |
Fused heterocyclic derivatives and methods of use
|
US8036664B2
(en)
*
|
2006-09-22 |
2011-10-11 |
Kineto Wireless, Inc. |
Method and apparatus for determining rove-out
|
EP2076128A4
(en)
*
|
2006-10-06 |
2011-01-05 |
|
PROTEIN CHINESE INHIBITOR AND ITS USE METHOD
|
GB0625283D0
(en)
*
|
2006-12-19 |
2007-01-24 |
Cyclacel Ltd |
Combination
|
ES2522169T3
(es)
*
|
2007-02-13 |
2014-11-13 |
Ab Science |
Forma polimorfa de derivado de 2-amino (nitroaril) tiazol
|
US20100143440A1
(en)
*
|
2007-04-30 |
2010-06-10 |
The Uab Research Foundation |
Ul97 inhibitors for treatment of proliferative disorders
|
ECSP077628A
(es)
|
2007-05-03 |
2008-12-30 |
Smithkline Beechman Corp |
Nueva composición farmacéutica
|
US7863315B2
(en)
*
|
2008-01-15 |
2011-01-04 |
Shenzhen Chipscreen Biosciences, Ltd. |
2-indolinone derivatives as selective histone deacetylase inhibitors
|
NZ587589A
(en)
|
2008-02-15 |
2012-10-26 |
Rigel Pharmaceuticals Inc |
Pyrimidine-2-amine compounds and their use as inhibitors of jak kinases
|
WO2009111644A2
(en)
*
|
2008-03-05 |
2009-09-11 |
The Regents Of The University Of Michigan |
Compositions and methods for diagnosing and treating pancreatic cancer
|
NZ589315A
(en)
|
2008-04-16 |
2012-11-30 |
Portola Pharm Inc |
2,6-diamino-pyrimidin-5-yl-carboxamides as Spleen tryosine kinase (syk) or Janus kinase (JAK) inhibitors
|
US8138339B2
(en)
|
2008-04-16 |
2012-03-20 |
Portola Pharmaceuticals, Inc. |
Inhibitors of protein kinases
|
EP2116236A1
(en)
|
2008-04-21 |
2009-11-11 |
Université de Mons-Hainaut |
Bisbenzamidine derivatives for use as antioxidant
|
EP2271631B1
(en)
|
2008-04-22 |
2018-07-04 |
Portola Pharmaceuticals, Inc. |
Inhibitors of protein kinases
|
WO2009135000A2
(en)
*
|
2008-04-30 |
2009-11-05 |
H. Lee Moffitt Cancer Center And Research Institute, Inc. |
Inhibition of shp2/ptpn11 protein tyrosine phosphatase by nsc-117199 and analogs
|
WO2009139834A1
(en)
*
|
2008-05-13 |
2009-11-19 |
Poniard Pharmaceuticals, Inc. |
Bioactive compounds for treatment of cancer and neurodegenerative diseases
|
EP2307002B1
(en)
|
2008-06-09 |
2013-01-02 |
Cyclacel Limited |
Combinations of sapacitabine or cndac with dna methyltransferase inhibitors such as decitabine and procaine
|
JP2012504646A
(ja)
*
|
2008-10-01 |
2012-02-23 |
ザ ユニバーシティ オブ ノース カロライナ アット チャペル ヒル |
選択的サイクリン依存性キナーゼ4/6阻害剤を用いた化学療法化合物に対する造血系の防護
|
JP2012504645A
(ja)
*
|
2008-10-01 |
2012-02-23 |
ザ ユニバーシティ オブ ノース カロライナ アット チャペル ヒル |
健康な細胞に対する電離放射線の影響を低下させる又は防止するための医薬組成物
|
WO2010121212A2
(en)
|
2009-04-17 |
2010-10-21 |
H. Lee Moffit Cancer Center And Research Institute, Inc. |
Indoline scaffold shp-2 inhibitors and method of treating cancer
|
JP2012526850A
(ja)
*
|
2009-05-13 |
2012-11-01 |
ザ ユニバーシティ オブ ノース カロライナ アット チャペル ヒル |
サイクリン依存性キナーゼ阻害剤及びその用法
|
ES2605593T3
(es)
|
2009-05-29 |
2017-03-15 |
Novartis Ag |
Métodos de administración de compuestos agonistas de trombopoyetina
|
BR112012002001A2
(pt)
*
|
2009-07-28 |
2016-05-10 |
Rigel Pharmaceuticals Inc |
método para tratar uma doença e/ou distúrbio do olho, formulação farmacêutica, e, kit
|
WO2011041584A2
(en)
|
2009-09-30 |
2011-04-07 |
President And Fellows Of Harvard College |
Methods for modulation of autophagy through the modulation of autophagy-enhancing gene products
|
US8652534B2
(en)
|
2009-10-14 |
2014-02-18 |
Berry Pharmaceuticals, LLC |
Compositions and methods for treatment of mammalian skin
|
BR112012010186B8
(pt)
*
|
2009-10-29 |
2021-05-25 |
Palau Pharma Sa |
derivados de heteroarila contendo n como inibidores de quinase jak3 e composição farmacêutica compreendendo os mesmos
|
US20120328568A1
(en)
|
2010-02-12 |
2012-12-27 |
Emory University |
Compositions and uses of lectins
|
MX2012010174A
(es)
|
2010-03-02 |
2012-11-30 |
Amakem Nv |
Inhibidores novedosos de rock.
|
CA2803697A1
(en)
|
2010-06-25 |
2011-12-29 |
Facultes Universitaires Notre Dame De La Paix |
Beta carboline derivatives useful in the treatment of proliferative disorders
|
US8785648B1
(en)
|
2010-08-10 |
2014-07-22 |
The Regents Of The University Of California |
PKC-epsilon inhibitors
|
CA2808655C
(en)
|
2010-08-18 |
2019-11-26 |
Emory University |
Compounds and compositions for ossification and methods related thereto
|
WO2012022780A1
(en)
|
2010-08-19 |
2012-02-23 |
Université Libre de Bruxelles |
18-beta-glycyrrhetinic acid derivatives with anti-tumor activity
|
SI2632467T1
(sl)
|
2010-10-25 |
2016-10-28 |
G1 Therapeutics, Inc. |
Inhibitorji CDK
|
US8691830B2
(en)
|
2010-10-25 |
2014-04-08 |
G1 Therapeutics, Inc. |
CDK inhibitors
|
US9868728B2
(en)
|
2010-10-29 |
2018-01-16 |
Emory University |
Quinazoline derivatives, compositions, and uses related thereto
|
EP2635557A2
(en)
|
2010-11-01 |
2013-09-11 |
Portola Pharmaceuticals, Inc. |
Nicotinamides as jak kinase modulators
|
GB201019043D0
(en)
|
2010-11-10 |
2010-12-22 |
Protea Biopharma N V |
Use of 2',5'-oligoadenylate derivative compounds
|
WO2012068381A2
(en)
|
2010-11-17 |
2012-05-24 |
The University Of North Carolina At Chapel Hill |
Protection of renal tissues from schema through inhibition of the proliferative kisses cdk4 and cdk6
|
EP2646430B1
(en)
|
2010-12-03 |
2016-09-21 |
Emory University |
Chemokine cxcr4 receptor modulators and uses related thereto
|
US8691777B2
(en)
|
2011-01-27 |
2014-04-08 |
Emory University |
Combination therapy
|
CA2827392A1
(en)
|
2011-02-24 |
2012-08-30 |
Emory University |
Noggin blocking compositions for ossification and methods related thereto
|
EP2678052B1
(en)
|
2011-02-24 |
2018-09-26 |
Emory University |
Jab1 blocking compositions for ossification and methods related thereto
|
US9365523B2
(en)
|
2011-03-31 |
2016-06-14 |
Emory University |
Imidazolyl amide compounds and uses related thereto
|
PL2696878T3
(pl)
|
2011-04-14 |
2020-01-31 |
Cyclacel Limited |
Schemat dawkowania dla sapacytabiny i decytabiny w kombinacji do leczenia ostrej białaczki szpikowej
|
US20140045936A1
(en)
|
2011-04-21 |
2014-02-13 |
Wake Forest University Health Sciences |
Cyclopropyl derivatives and methods of use
|
GB201107223D0
(en)
|
2011-04-29 |
2011-06-15 |
Amakem Nv |
Novel rock inhibitors
|
WO2012152807A1
(en)
|
2011-05-09 |
2012-11-15 |
Universiteit Antwerpen |
Activity-based probes for the urokinase plasminogen activator
|
GB201108225D0
(en)
|
2011-05-17 |
2011-06-29 |
Amakem Nv |
Novel KBC inhibitors
|
EP2721011B1
(en)
|
2011-06-20 |
2017-09-06 |
Emory University |
Prostaglandin receptor ep2 antagonists, derivatives, compositions, and uses related thereto
|
GB201113689D0
(en)
|
2011-08-09 |
2011-09-21 |
Amakem Nv |
Novel PDE4 inhibitors
|
CA2848726C
(en)
|
2011-08-19 |
2019-09-10 |
Emory University |
Bax agonist, compositions, and methods related thereto
|
GB201114854D0
(en)
|
2011-08-29 |
2011-10-12 |
Amakem Nv |
Novel rock inhibitors
|
US9079858B2
(en)
|
2011-08-31 |
2015-07-14 |
Amakem Nv |
Rock kinase inhibitors
|
CA2849999A1
(en)
|
2011-09-30 |
2013-04-04 |
Oncodesign S.A. |
Macrocyclic flt3 kinase inhibitors
|
HUE029728T2
(en)
|
2011-09-30 |
2017-03-28 |
Ipsen Pharma Sas |
Macrocyclic LRRK2 kinase inhibitors
|
GB201119358D0
(en)
|
2011-11-10 |
2011-12-21 |
Lewi Paulus J |
Disubstituted triazine dimers for treatment and/or prevention of infectious diseases
|
DE102011119127A1
(de)
*
|
2011-11-22 |
2013-05-23 |
Merck Patent Gmbh |
3-Cyanaryl-1H-pyrrolo[2.3-b]pyridin-Derivate
|
IN2014CN04065A
(et)
|
2011-11-23 |
2015-09-04 |
Portola Pharm Inc |
|
PL2810198T3
(pl)
|
2012-01-30 |
2024-01-22 |
Universiteit Gent |
Związki przeciwinwazyjne
|
GB201204756D0
(en)
|
2012-03-19 |
2012-05-02 |
Lewi Paulus J |
Triazines with suitable spacers for treatment and/or prevention of HIV infections
|
EP3216792B1
(en)
|
2012-03-29 |
2020-05-27 |
G1 Therapeutics, Inc. |
Lactam kinase inhibitors
|
US20150110723A1
(en)
|
2012-05-31 |
2015-04-23 |
Emory University |
Quinazoline derivatives, compositions, and uses related thereto
|
EP2877461B1
(en)
|
2012-07-27 |
2018-05-09 |
Emory University |
Heterocyclic flavone derivatives, compositions, and methods related thereto
|
WO2014058921A2
(en)
|
2012-10-08 |
2014-04-17 |
Portola Pharmaceuticals, Inc. |
Substituted pyrimidinyl kinase inhibitors
|
WO2014059034A2
(en)
|
2012-10-09 |
2014-04-17 |
President And Fellows Of Harvard College |
Nad biosynthesis and precursors for the treatment and prevention of cancer and proliferation
|
CN107868071B
(zh)
|
2012-11-05 |
2021-07-20 |
爱默蕾大学 |
7,8-二羟黄酮和7,8-取代的黄酮衍生物、组合物及其相关方法
|
WO2014072419A1
(en)
|
2012-11-08 |
2014-05-15 |
Universiteit Antwerpen |
Novel anti-hiv compounds
|
CN105026387B
(zh)
|
2013-01-29 |
2018-06-08 |
Redx制药公开有限公司 |
作为软rock抑制剂的吡啶衍生物
|
US9572815B2
(en)
|
2013-03-15 |
2017-02-21 |
St. Jude Children's Research Hospital |
Methods and compositions of p27KIP1 transcriptional modulators
|
CN105407889B
(zh)
|
2013-03-15 |
2018-06-01 |
G1治疗公司 |
针对Rb阳性异常细胞增殖的HSPC节制性治疗
|
CA2906262A1
(en)
|
2013-03-15 |
2014-09-18 |
Oncodesign S.A. |
Macrocyclic salt-inducible kinase inhibitors
|
JP6435315B2
(ja)
|
2013-03-15 |
2018-12-05 |
ジー1、セラピューティクス、インコーポレイテッドG1 Therapeutics, Inc. |
高活性抗新生物薬及び抗増殖剤
|
KR101548803B1
(ko)
*
|
2013-09-09 |
2015-09-01 |
경북대학교병원 |
3(6(4(트리플루오로메톡시)페닐아미노)피리미딘4일)벤자미드 또는 이의 약학적으로 허용 가능한 염을 유효성분으로 함유하는 당뇨병의 예방 또는 치료용 약학적 조성물
|
TW201542581A
(zh)
|
2013-09-11 |
2015-11-16 |
Univ Emory |
核苷酸與核苷治療組成物及其相關用途
|
US10188738B2
(en)
|
2013-10-16 |
2019-01-29 |
Université Libre de Bruxelles |
Formulations useful in the treatment of proliferative diseases affecting the respiratory tract
|
CN103588758A
(zh)
*
|
2013-11-04 |
2014-02-19 |
南京大学 |
一类含1,4-苯并二噁烷骨架的硝基咪唑衍生物的合成、制备及其在抗癌药物中的应用
|
DK3068888T3
(en)
|
2013-11-12 |
2018-05-07 |
Univ Brussel Vrije |
RNA TRANSCRIPTION VECTOR AND APPLICATIONS THEREOF
|
WO2015081282A1
(en)
*
|
2013-11-27 |
2015-06-04 |
Redwood Bioscience, Inc. |
Hydrazinyl-pyrrolo compounds and methods for producing a conjugate
|
KR101602203B1
(ko)
*
|
2014-03-11 |
2016-03-11 |
경북대학교병원 |
N(2하이드록시에틸)3(6(4(트리플루오로메톡시)페닐아미노)피리미딘-4-일)벤자미드 또는 이의 약학적으로 허용 가능한 염을 유효성분으로 함유하는 당뇨병의 예방 또는 치료용 약학적 조성물
|
WO2015150337A1
(en)
|
2014-04-01 |
2015-10-08 |
Amakem Nv |
Lim kinase inhibitors
|
US20170165240A1
(en)
|
2014-04-01 |
2017-06-15 |
Université Libre de Bruxelles |
New strategies for treating melanoma
|
WO2015161283A1
(en)
|
2014-04-17 |
2015-10-22 |
G1 Therapeutics, Inc. |
Tricyclic lactams for use in hspc-sparing treatments for rb-positive abnormal cellular proliferation
|
CN106458821B
(zh)
|
2014-05-05 |
2019-12-31 |
爱默蕾大学 |
Bh4拮抗剂及其相关方法
|
WO2015175855A1
(en)
|
2014-05-16 |
2015-11-19 |
Emory University |
Chemokine cxcr4 and ccr5 receptor modulators and used related thereto
|
EP3180003B1
(en)
|
2014-07-01 |
2022-01-12 |
The Regents of the University of California |
Pkc-epsilon inhibitors
|
US10023602B2
(en)
|
2014-07-08 |
2018-07-17 |
Universiteit Gent |
Hamamelitannin analogues and uses thereof
|
WO2016040858A1
(en)
|
2014-09-12 |
2016-03-17 |
G1 Therapeutics, Inc. |
Combinations and dosing regimes to treat rb-positive tumors
|
WO2016040848A1
(en)
|
2014-09-12 |
2016-03-17 |
G1 Therapeutics, Inc. |
Treatment of rb-negative tumors using topoisomerase inhibitors in combination with cyclin dependent kinase 4/6 inhibitors
|
ES2717510T3
(es)
|
2014-09-17 |
2019-06-21 |
Oncodesign Sa |
Inhibidores macrocíclicos de cinasa LRRK2
|
BR112017004035B1
(pt)
|
2014-09-17 |
2023-11-14 |
Oncodesign Precision Medicine (OPM) |
Inibidores macrocíclicos de rip2 quinase e composições farmacêuticas
|
WO2016083490A1
(en)
|
2014-11-27 |
2016-06-02 |
Remynd Nv |
Compounds for the treatment of amyloid-associated diseases
|
JP6735751B2
(ja)
|
2014-12-15 |
2020-08-05 |
エモリー ユニバーシティー |
B型肝炎ウイルスの治療のためのホスホルアミデート
|
DK3236972T3
(en)
|
2014-12-26 |
2021-10-04 |
Univ Emory |
Antivirale N4-hydroxycytidin-derivativer
|
WO2016146651A1
(en)
|
2015-03-16 |
2016-09-22 |
Oncodesign Sa |
Macrocyclic activin-like receptor kinase inhibitors
|
CN108025187A
(zh)
|
2015-04-28 |
2018-05-11 |
新南创新私人有限公司 |
靶向nad+以治疗化学疗法和放射疗法引发的认知损害、神经病变和不活动
|
US10555918B2
(en)
|
2015-05-29 |
2020-02-11 |
Emory University |
2-amino-N′-benzylideneacetohydrazides and derivatives for the management of CFTR protein mediated diseases
|
US20180161340A1
(en)
*
|
2015-06-18 |
2018-06-14 |
St. Jude Children's Research Hospital |
Methods and compositions for the prevention and treatment of hearing loss
|
US10716869B2
(en)
|
2016-02-29 |
2020-07-21 |
Oncodesign Sa |
Radiolabeled macrocyclic EGFR inhibitor
|
WO2017157882A1
(en)
|
2016-03-14 |
2017-09-21 |
Université Catholique de Louvain |
Serine biosynthetic pathway inhibitors
|
WO2017161253A1
(en)
*
|
2016-03-18 |
2017-09-21 |
Tufts Medical Center |
Compositions and methods for treating and preventing metabolic disorders
|
WO2017189978A1
(en)
|
2016-04-28 |
2017-11-02 |
Emory University |
Alkyne containing nucleotide and nucleoside therapeutic compositions and uses related thereto
|
US11166967B2
(en)
|
2016-05-19 |
2021-11-09 |
Universiteit Antwerpen |
Bis(acetamidophenyl) guanidinophenylethylphosphonates for use in the prevention and/or treatment of PAR-related diseases
|
BE1023757B1
(nl)
|
2016-06-30 |
2017-07-12 |
Yun NV |
Bewaring van micro-organismen
|
WO2018065387A1
(en)
|
2016-10-04 |
2018-04-12 |
Universiteit Gent |
Novel hamamelitannin analogues and uses thereof
|
EP3532488A4
(en)
|
2016-10-14 |
2020-04-29 |
Emory University |
NANOPARTICLES WITH MOLECULES FOR BINDING OR BLOCKING PD-L1 AND USED IN THE TREATMENT OF CANCER
|
CN110049866B
(zh)
|
2016-10-26 |
2022-04-05 |
爱默蕾大学 |
多金属氧酸盐络合物在制备用于治疗癌症的药物组合物中的用途以及该药物组合物
|
EP3544952A1
(en)
|
2016-11-24 |
2019-10-02 |
Universiteit Antwerpen |
Halogenated benzotropolones as atg4b inhibitors
|
US10898544B2
(en)
|
2016-12-13 |
2021-01-26 |
Emory University |
Polypeptides for managing viral infections
|
CN110177554B
(zh)
|
2017-01-06 |
2023-06-02 |
G1治疗公司 |
用于治疗癌症的组合疗法
|
EP3573608A1
(en)
|
2017-01-30 |
2019-12-04 |
Université de Liège |
Perk and ire-1a inhibitors against neurodevelopmental disorders
|
WO2018156595A1
(en)
|
2017-02-21 |
2018-08-30 |
Emory University |
Chemokine cxcr4 receptor modulators and uses related thereto
|
US10981896B2
(en)
|
2017-03-02 |
2021-04-20 |
Board Of Regents, The University Of Texas System |
Indolinone derivatives as inhibitors of maternal embryonic leucine zipper kinase
|
CN106977508A
(zh)
*
|
2017-05-05 |
2017-07-25 |
遵义医学院 |
具有靛红结构的吡唑衍生物用于防治肿瘤的药物及其制法
|
DK3621963T3
(da)
|
2017-05-11 |
2024-04-15 |
Remynd N V |
Forbindelser til behandling af epilepsi, neurodegenerative lidelser og andre CNS-lidelser
|
US11661581B2
(en)
*
|
2017-05-25 |
2023-05-30 |
University Of Massachusetts |
Use of CDK inhibitors to enhance growth and self-renewal of progenitor cells
|
CN110913861B
(zh)
|
2017-06-29 |
2024-01-09 |
G1治疗公司 |
G1t38的形态学形式及其制造方法
|
SG11202004403QA
(en)
|
2017-12-07 |
2020-06-29 |
Univ Emory |
N4-hydroxycytidine and derivatives and anti-viral uses related thereto
|
WO2019193091A1
(en)
|
2018-04-05 |
2019-10-10 |
Universiteit Hasselt |
Selective pde4d inhibitors against demyelinating diseases
|
EP3813882B1
(en)
|
2018-06-29 |
2023-08-09 |
Rejuvenate Biomed |
Pharmaceutical combination comprising a biguanid and an acetylcholinesterase inhibitor for use in age-related and/or degenerative diseases
|
US20210292335A1
(en)
|
2018-08-07 |
2021-09-23 |
Emory University |
Heterocyclic Flavone Derivatives, Compositions, and Methods Related Thereto
|
EP3840756A4
(en)
|
2018-08-24 |
2022-04-27 |
G1 Therapeutics, Inc. |
IMPROVED SYNTHESIS OF 1,4-DIAZASPIRO[5.5]UNDECAN-3-ONE
|
EP3843845A4
(en)
|
2018-08-29 |
2022-05-11 |
University Of Massachusetts |
INHIBITION OF PROTEIN KINASE FOR THE TREATMENT OF FRIEDREICH'S ATAXIA
|
EP3860976A1
(en)
*
|
2018-10-05 |
2021-08-11 |
Ichnos Sciences S.A. |
Indolinone compounds for use as map4k1 inhibitors
|
CN114206864A
(zh)
|
2019-05-14 |
2022-03-18 |
苏州四体康宸医药科技有限公司 |
喹唑啉-2.4-二酮衍生物作为parp抑制剂
|
JP2023514443A
(ja)
|
2020-02-24 |
2023-04-05 |
カトリーケ、ユニベルシテート、ルーベン |
ピロロピリジンおよびイミダゾピリジン抗ウイルス化合物
|
GB202003240D0
(en)
|
2020-03-05 |
2020-04-22 |
Ecosynth Nv |
Antiviral treatment
|
US10988479B1
(en)
|
2020-06-15 |
2021-04-27 |
G1 Therapeutics, Inc. |
Morphic forms of trilaciclib and methods of manufacture thereof
|
WO2022020114A2
(en)
|
2020-07-10 |
2022-01-27 |
Ting Therapeutics Llc |
Methods for the prevention and treatment of hearing loss
|
WO2022157381A1
(en)
|
2021-01-25 |
2022-07-28 |
Universiteit Hasselt |
Phloretin for use in the treatment of neurodegenerative and demyelinating diseases
|
WO2022191501A1
(ko)
*
|
2021-03-12 |
2022-09-15 |
주식회사 온코크로스 |
항암제 내성 암의 치료를 위한 조성물
|
US20230022525A1
(en)
|
2021-07-26 |
2023-01-26 |
Celcuity Inc. |
Methods for the treatment of cancer using 1-(4-{[4-(dimethylamino)piperidin-1-yl]carbonyl}phenyl)-3-[4-(4,6-dimorpholin-4-yl-1,3,5-triazin-2-yl)phenyl]urea
|
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|
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|
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|
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|
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|
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|
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|
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|
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|
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|
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|
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|
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|
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|
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|
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|
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|
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|
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|
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|
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|
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|
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|
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