EA201301320A1 - 4-арил-n-фенил-1,3,5-триазин-2-амины, которые содержат сульфоксиминную группу - Google Patents

4-арил-n-фенил-1,3,5-триазин-2-амины, которые содержат сульфоксиминную группу

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Publication number
EA201301320A1
EA201301320A1 EA201301320A EA201301320A EA201301320A1 EA 201301320 A1 EA201301320 A1 EA 201301320A1 EA 201301320 A EA201301320 A EA 201301320A EA 201301320 A EA201301320 A EA 201301320A EA 201301320 A1 EA201301320 A1 EA 201301320A1
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EA
Eurasian Patent Office
Prior art keywords
amines
aryl
phenyl
contain
group
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EA201301320A
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English (en)
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EA023418B1 (ru
Inventor
Ульрих Люккинг
Рольф Больманн
Арне Шольц
Герхард Зимайстер
Марк Жан Гнот
Ульф Бёмер
Дирк Коземунд
Филип Линау
Герд Рютер
Карстен Шультц-Фадемрехт
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Байер Интеллектчуал Проперти Гмбх
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=46085997&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EA201301320(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from EP11167317A external-priority patent/EP2527332A1/en
Application filed by Байер Интеллектчуал Проперти Гмбх filed Critical Байер Интеллектчуал Проперти Гмбх
Publication of EA201301320A1 publication Critical patent/EA201301320A1/ru
Publication of EA023418B1 publication Critical patent/EA023418B1/ru

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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/53—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
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    • C07D251/16—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hydrogen or carbon atoms directly attached to at least one ring carbon atom to only one ring carbon atom
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    • C07D251/26—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with only hetero atoms directly attached to ring carbon atoms
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Abstract

Настоящее изобретение относится к 4-арил-N-фенил-1,3,5-триазин-2-аминам, которые содержат сульфоксиминную группу общей формулы (I) или (Ia), как описано и определено в данном описании, и способам их получения, их применению для лечения и/или профилактики гиперпролиферативных нарушений, вирусно индуцированных инфекционных заболеваний и/или сердечно-сосудистых заболеваний. Изобретение также относится к соединениям промежуточных веществ, пригодных для получения указанных соединений общей формулы (I) или (Ia).
EA201301320A 2011-05-24 2012-05-21 4-арил-n-фенил-1,3,5-триазин-2-амины, которые содержат сульфоксиминную группу EA023418B1 (ru)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EP11167317A EP2527332A1 (en) 2011-05-24 2011-05-24 4-Aryl-N-phenyl-1,3,5-triazin-2-amines containing a sulfoximine group as CDK9 inhibitors
EP11180759 2011-09-09
EP12158030 2012-03-05
PCT/EP2012/059399 WO2012160034A1 (en) 2011-05-24 2012-05-21 4-aryl-n-phenyl-1,3,5-triazin-2-amines containing a sulfoximine group

Publications (2)

Publication Number Publication Date
EA201301320A1 true EA201301320A1 (ru) 2014-05-30
EA023418B1 EA023418B1 (ru) 2016-06-30

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EA201301320A EA023418B1 (ru) 2011-05-24 2012-05-21 4-арил-n-фенил-1,3,5-триазин-2-амины, которые содержат сульфоксиминную группу

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US (2) US9669034B2 (ru)
EP (1) EP2714654B1 (ru)
JP (1) JP5955948B2 (ru)
KR (1) KR101958501B1 (ru)
CN (1) CN103702979B (ru)
AP (1) AP3884A (ru)
AR (1) AR086552A1 (ru)
AU (1) AU2012260983B2 (ru)
BR (1) BR112013029976A2 (ru)
CA (1) CA2837027C (ru)
CL (1) CL2013003360A1 (ru)
CO (1) CO6811860A2 (ru)
CR (1) CR20130620A (ru)
CU (1) CU24175B1 (ru)
CY (1) CY1116791T1 (ru)
DK (1) DK2714654T3 (ru)
DO (1) DOP2013000277A (ru)
EA (1) EA023418B1 (ru)
EC (1) ECSP13013040A (ru)
ES (1) ES2549529T3 (ru)
GT (1) GT201300293A (ru)
HR (1) HRP20151060T1 (ru)
HU (1) HUE027853T2 (ru)
IL (1) IL229314A (ru)
JO (1) JO3204B1 (ru)
MA (1) MA35132B1 (ru)
ME (1) ME02227B (ru)
MX (1) MX340803B (ru)
MY (1) MY165748A (ru)
PE (1) PE20141075A1 (ru)
PL (1) PL2714654T3 (ru)
PT (1) PT2714654E (ru)
RS (1) RS54264B1 (ru)
SG (2) SG194856A1 (ru)
SI (1) SI2714654T1 (ru)
TN (1) TN2013000485A1 (ru)
TW (2) TW201636330A (ru)
UA (1) UA112870C2 (ru)
UY (1) UY34095A (ru)
WO (1) WO2012160034A1 (ru)
ZA (1) ZA201309672B (ru)

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RU2745269C2 (ru) * 2015-05-08 2021-03-22 Ф. Хоффманн-Ля Рош Аг Новые соединения и производные сульфонимидоилпуринона для лечения и профилактики вирусной инфекции

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