EA201270186A1 - Фармацевтические композиции, содержащие модифицированные фуканы, для использования при лечении фиброзных спаек и других нарушений - Google Patents

Фармацевтические композиции, содержащие модифицированные фуканы, для использования при лечении фиброзных спаек и других нарушений

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Publication number
EA201270186A1
EA201270186A1 EA201270186A EA201270186A EA201270186A1 EA 201270186 A1 EA201270186 A1 EA 201270186A1 EA 201270186 A EA201270186 A EA 201270186A EA 201270186 A EA201270186 A EA 201270186A EA 201270186 A1 EA201270186 A1 EA 201270186A1
Authority
EA
Eurasian Patent Office
Prior art keywords
fukans
violations
pharmaceutical compositions
compositions containing
containing modified
Prior art date
Application number
EA201270186A
Other languages
English (en)
Inventor
Кристофер Майкл Кевин Спрингейт
Original Assignee
ЭйАрСи МЕДИКАЛ ДИВАЙСИЗ, ИНК.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by ЭйАрСи МЕДИКАЛ ДИВАЙСИЗ, ИНК. filed Critical ЭйАрСи МЕДИКАЛ ДИВАЙСИЗ, ИНК.
Publication of EA201270186A1 publication Critical patent/EA201270186A1/ru

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/737Sulfated polysaccharides, e.g. chondroitin sulfate, dermatan sulfate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/06Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/10Anti-acne agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • A61P39/02Antidotes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/005Preparations for sensitive skin
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08BPOLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0006Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00Preparations for use in therapy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Dermatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Birds (AREA)
  • Polymers & Plastics (AREA)
  • Materials Engineering (AREA)
  • Biochemistry (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Toxicology (AREA)
  • Diabetes (AREA)
  • Rheumatology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Oncology (AREA)
  • Surgery (AREA)
  • Communicable Diseases (AREA)
  • Hematology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)

Abstract

Композиция, содержащая агенты фукана и применение указанных композиций для лечения, профилактики, ингибирования и т.д. фиброзных спаек, перитонита, ишемии, реперфузионного поражения, эндотоксикоза, келоидов и рубцевания в виде келоидного шва, дерматита и розацеа. Предпочтительные агенты фукана отличаются распределением их молекулярной массы.
EA201270186A 2009-07-27 2010-07-27 Фармацевтические композиции, содержащие модифицированные фуканы, для использования при лечении фиброзных спаек и других нарушений EA201270186A1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US22892909P 2009-07-27 2009-07-27
PCT/CA2010/001175 WO2011011881A1 (en) 2009-07-27 2010-07-27 Pharmaceutical compositions comprising modified fucans for use in the treatment of fibrous adhesions and other disorders

Publications (1)

Publication Number Publication Date
EA201270186A1 true EA201270186A1 (ru) 2012-09-28

Family

ID=43497856

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201270186A EA201270186A1 (ru) 2009-07-27 2010-07-27 Фармацевтические композиции, содержащие модифицированные фуканы, для использования при лечении фиброзных спаек и других нарушений

Country Status (19)

Country Link
US (6) US8466125B2 (ru)
EP (2) EP3300737A1 (ru)
JP (5) JP2013500274A (ru)
KR (1) KR20120083297A (ru)
CN (2) CN106176798A (ru)
AR (1) AR078082A1 (ru)
AU (4) AU2010278640A1 (ru)
BR (1) BR112012008072A2 (ru)
CA (2) CA3046665C (ru)
CL (1) CL2012000215A1 (ru)
EA (1) EA201270186A1 (ru)
IN (1) IN2012DN01314A (ru)
JO (1) JO3676B1 (ru)
MX (1) MX2012001212A (ru)
MY (1) MY168759A (ru)
SG (3) SG10201808960VA (ru)
TW (2) TWI569801B (ru)
WO (1) WO2011011881A1 (ru)
ZA (1) ZA201200999B (ru)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11628183B2 (en) 2018-07-27 2023-04-18 ARC Medical Ine. Highly purified fucans for the treatment of fibrous adhesions

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1809303B1 (en) * 2004-09-23 2019-03-06 ARC Medical Devices, Inc. Pharmaceutical compositions and methods relating to inhibiting fibrous adhesions or inflammatory disease using low sulphate fucans
JO3676B1 (ar) * 2009-07-27 2020-08-27 Arc Medical Devices Inc مركبات صيدلانية تضم فوكانات معدلة وطرق تتعلق بها
WO2011109469A1 (en) * 2010-03-03 2011-09-09 Neocutis Sa Compositions and methods for treatment of skin diseases and disorders using antimicrobial peptide sequestering compounds
FR2984126B1 (fr) * 2011-12-20 2014-08-22 Oreal Polysaccharides sulfates agent antipelliculaire
CA2976142A1 (en) 2015-02-16 2016-08-25 Gilles Henri LASSERRE Composition for prevention or treatment of cutaneous disorder
CN105663154B (zh) * 2016-01-18 2020-06-30 首都医科大学 褐藻多糖硫酸酯在制备预防和/或治疗下肢外周动脉血管病的产品中的应用
US20180056087A1 (en) * 2016-08-26 2018-03-01 Adolfo Ribeiro Wearable Micro-LED Healing Bandage
CN106943619A (zh) * 2017-03-17 2017-07-14 清华大学 一种液体伤口敷料及其制备方法
CN115260328A (zh) * 2022-08-14 2022-11-01 湘潭大学 一种改性岩藻多糖化合物及其制备方法和应用

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US5605938A (en) * 1991-05-31 1997-02-25 Gliatech, Inc. Methods and compositions for inhibition of cell invasion and fibrosis using dextran sulfate
IT1288713B1 (it) * 1996-12-18 1998-09-23 Crinos Industria Farmaco Fucani a basso peso molecolare aventi attivita' anticoagulante antitrombinica e antitrombotica
FR2772618B1 (fr) * 1997-12-18 2000-02-18 Ifremer Utilisation de fucane comme regulateur de la reconstruction des tissus conjonctifs
ATE367166T1 (de) * 1999-08-20 2007-08-15 Takara Bio Inc Heilmittel
US6812220B2 (en) * 2001-08-29 2004-11-02 University Of British Columbia Pharmaceutical compositions and methods relating to fucans
NO320671B1 (no) * 2001-11-30 2006-01-16 Fmc Biopolymer As Fremgangsmate for a stimulere vektokning i fisk.
CN1829501A (zh) 2003-05-30 2006-09-06 Arc药品有限公司 涉及使用多种药物抑制纤维粘连的药用组合物和方法
BRPI0418384A (pt) * 2003-05-30 2007-06-26 Arc Pharmaceuticals Inc composições farmacêuticas e métodos referentes à inibição de adesões fibrosas utilizando diversos agentes
EP1809303B1 (en) * 2004-09-23 2019-03-06 ARC Medical Devices, Inc. Pharmaceutical compositions and methods relating to inhibiting fibrous adhesions or inflammatory disease using low sulphate fucans
WO2007028256A2 (en) * 2005-09-09 2007-03-15 Les Biotechnologies Oceanova Inc. Polysaccharides compositions comprising fucans and galactans and their use to reduce extravasation and inflammation
CN1935154A (zh) * 2006-09-04 2007-03-28 北京世纪博康医药科技有限公司 褐藻多糖硫酸酯在制备治疗心脑血管疾病的药物中的用途
KR101486931B1 (ko) * 2007-02-23 2015-01-27 박스터 인터내쇼날 인코포레이티드 해조류 추출물로부터 푸코이단을 정제하는 방법
GB0707096D0 (en) * 2007-04-12 2007-05-23 Ntnu Technology Transfer As Method
JO3676B1 (ar) * 2009-07-27 2020-08-27 Arc Medical Devices Inc مركبات صيدلانية تضم فوكانات معدلة وطرق تتعلق بها

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11628183B2 (en) 2018-07-27 2023-04-18 ARC Medical Ine. Highly purified fucans for the treatment of fibrous adhesions
US11642368B2 (en) 2018-07-27 2023-05-09 ARC Medical Inc. Highly purified and/or modified fucan compositions for the treatment of fibrous adhesions
US11938145B2 (en) 2018-07-27 2024-03-26 ARC Medical Inc. Low endotoxin fucan compositions, systems, and methods

Also Published As

Publication number Publication date
TWI491396B (zh) 2015-07-11
AU2018203461A1 (en) 2018-06-07
JP2016128491A (ja) 2016-07-14
EP2459200A4 (en) 2013-02-27
CA2769147A1 (en) 2011-02-03
KR20120083297A (ko) 2012-07-25
MX2012001212A (es) 2012-07-17
TW201105342A (en) 2011-02-16
US20140128340A1 (en) 2014-05-08
SG10201808960VA (en) 2018-11-29
AU2016219615A1 (en) 2016-09-15
AU2010278640A1 (en) 2012-03-15
CN102665733A (zh) 2012-09-12
ZA201200999B (en) 2013-05-29
CN106176798A (zh) 2016-12-07
US8466125B2 (en) 2013-06-18
WO2011011881A1 (en) 2011-02-03
MY168759A (en) 2018-12-04
TWI569801B (zh) 2017-02-11
JP2013500274A (ja) 2013-01-07
CA3046665C (en) 2021-03-23
IN2012DN01314A (ru) 2015-06-05
EP3300737A1 (en) 2018-04-04
TW201532607A (zh) 2015-09-01
JO3676B1 (ar) 2020-08-27
CN102665733B (zh) 2016-08-10
AR078082A1 (es) 2011-10-12
AU2019268096A1 (en) 2019-12-12
BR112012008072A2 (pt) 2016-03-01
JP2021020907A (ja) 2021-02-18
US20180051097A1 (en) 2018-02-22
US20140274942A1 (en) 2014-09-18
EP2459200A1 (en) 2012-06-06
US20180230240A1 (en) 2018-08-16
CA3046665A1 (en) 2011-02-03
JP2017206542A (ja) 2017-11-24
US20110021457A1 (en) 2011-01-27
SG10201401436VA (en) 2014-10-30
JP2019142896A (ja) 2019-08-29
SG177741A1 (en) 2012-02-28
CL2012000215A1 (es) 2012-07-13
US20200115472A1 (en) 2020-04-16

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