EA200701650A1 - Гранулирование из расплава композиции, содержащей кальцийсодержащее соединение - Google Patents
Гранулирование из расплава композиции, содержащей кальцийсодержащее соединениеInfo
- Publication number
- EA200701650A1 EA200701650A1 EA200701650A EA200701650A EA200701650A1 EA 200701650 A1 EA200701650 A1 EA 200701650A1 EA 200701650 A EA200701650 A EA 200701650A EA 200701650 A EA200701650 A EA 200701650A EA 200701650 A1 EA200701650 A1 EA 200701650A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- calcium
- containing compound
- melt
- granulation
- composition containing
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
- A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
- A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Physical Education & Sports Medicine (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Gasification And Melting Of Waste (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
Abstract
Новый способ приготовления таблетки, содержащей кальцийсодержащее соединение, где способ предусматривает процесс гранулирования из расплава, во время которого сахарный спирт плавится и заливает кальцийсодержащее соединение так, что, по существу, достигается достаточная маскировка мелового вкуса и, по существу, устраняются неприятные ощущения во рту, вызываемые кальцийсодержащим соединением, и то же время объем таблетки получается низким. Способ по изобретению особенно подходит для производства таблеток с высоким содержанием кальцийсодержащего соединения.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DKPA200500167 | 2005-02-03 | ||
PCT/IB2006/000188 WO2006082499A1 (en) | 2005-02-03 | 2006-02-02 | Melt granulation of a composition containing a calcium-containing compound |
Publications (2)
Publication Number | Publication Date |
---|---|
EA200701650A1 true EA200701650A1 (ru) | 2007-12-28 |
EA010751B1 EA010751B1 (ru) | 2008-10-30 |
Family
ID=34974581
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EA200701650A EA010751B1 (ru) | 2005-02-03 | 2006-02-02 | Гранулирование из расплава композиции, содержащей кальцийсодержащее соединение |
Country Status (10)
Country | Link |
---|---|
US (1) | US8846088B2 (ru) |
EP (1) | EP1845949B1 (ru) |
JP (1) | JP5224820B2 (ru) |
AT (1) | ATE395908T1 (ru) |
CA (1) | CA2601755C (ru) |
DE (1) | DE602006001295D1 (ru) |
EA (1) | EA010751B1 (ru) |
ES (1) | ES2306431T3 (ru) |
NO (1) | NO20074481L (ru) |
WO (1) | WO2006082499A1 (ru) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE102008047910A1 (de) | 2008-09-19 | 2010-03-25 | Molkerei Meggle Wasserburg Gmbh & Co. Kg | Tablettierhilfsstoff auf Laktose- und Cellulosebasis |
JP5523467B2 (ja) * | 2008-11-17 | 2014-06-18 | タケダ ニコメド エイエス | 炭酸カルシウム錠剤の改善された溶解安定性 |
MX2012001893A (es) * | 2009-08-18 | 2012-03-16 | Cargill Inc | Tableteado de eritritol e isomaltosa. |
JO3752B1 (ar) | 2011-06-10 | 2021-01-31 | Schweitzer Mauduit Int Inc | مواد تبغ تحتوي على جسيمات دقيقة من كربونات الكالسيوم غير متساوية القياس |
CN102495068B (zh) * | 2011-12-01 | 2014-01-08 | 浙江工商大学 | 大米垩白米在线检测方法 |
CA2937365C (en) | 2016-03-29 | 2018-09-18 | F. Hoffmann-La Roche Ag | Granulate formulation of 5-methyl-1-phenyl-2-(1h)-pyridone and method of making the same |
WO2017185040A1 (en) | 2016-04-22 | 2017-10-26 | University Of Mississippi | Twin-screw dry granulation for producing solid formulations |
CN111743917B (zh) * | 2020-07-10 | 2023-09-05 | 天津天狮生物发展有限公司 | 酶解骨粉和异麦芽酮糖醇混合颗粒的制备方法 |
WO2023088885A1 (en) * | 2021-11-16 | 2023-05-25 | Dsm Ip Assets B.V. | Granules obtainable by continuous melt granulation |
WO2023088886A1 (en) | 2021-11-16 | 2023-05-25 | Dsm Ip Assets B.V. | High potency granules obtainable by continuous melt granulation |
IT202100030935A1 (it) * | 2021-12-09 | 2023-06-09 | Fidia Farm Spa | Compresse comprendenti condroitin solfato, glucosamina cloridrato e vitamina c per il trattamento di danni cartilaginei, tendinei, ossei |
Family Cites Families (31)
Publication number | Priority date | Publication date | Assignee | Title |
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JPS58214333A (ja) * | 1982-06-04 | 1983-12-13 | Dai Ichi Seiyaku Co Ltd | 粒状物 |
US4446135A (en) | 1982-06-07 | 1984-05-01 | Sterling Drug Inc. | Chewable antacid tablets |
US4698264A (en) | 1982-08-02 | 1987-10-06 | Durkee Industrial Foods, Corp. | Particulate composition and process for making same |
CA1279574C (en) | 1985-04-17 | 1991-01-29 | Jeffrey L. Finnan | Process for lubricating water-soluble vitamin powders |
JPH01317374A (ja) * | 1988-06-17 | 1989-12-22 | Towa Kasei Kogyo Kk | 冷凍魚肉すり身添加用品質改良剤及びそれを用いた冷凍魚肉すり身の製造法 |
DE4006734C1 (ru) | 1990-03-03 | 1991-07-25 | Benckiser-Knapsack Gmbh, 6802 Ladenburg, De | |
US5204115A (en) | 1990-12-12 | 1993-04-20 | Suomen Xyrofin Oy | Directly compressible xylitol and method |
JP2995226B2 (ja) | 1992-03-03 | 1999-12-27 | 日本ワイスレダリー株式会社 | カルシウム含有チユアブル錠 |
US5405623A (en) | 1993-09-22 | 1995-04-11 | Wm. Wrigley Jr. Company | Chewing gum compositions and methods for manufacturing same |
DE4427137B4 (de) | 1993-10-07 | 2007-08-23 | Degussa Gmbh | Fällungskieselsäure |
FR2724844B1 (fr) * | 1994-09-23 | 1997-01-24 | Innothera Lab Sa | Association therapeutique vitamino-calcique, son procede d'obtention et son utilisation |
DE19617487A1 (de) | 1996-05-02 | 1997-11-06 | Merck Patent Gmbh | Geschmacksverbesserung von Arzneimittelwirkstoffen |
CN1154479C (zh) | 1996-06-14 | 2004-06-23 | 协和发酵工业株式会社 | 口腔内快速崩解片剂 |
CN1193026A (zh) | 1997-03-06 | 1998-09-16 | 赵小英 | 光和生物可环境降解母料 |
FR2762217B1 (fr) | 1997-04-16 | 2000-09-29 | Besins Iscovesco Lab | Preparation solide vitamino-calcique, son procede d'obtention et son utilisation |
ITFI970184A1 (it) | 1997-07-30 | 1999-01-30 | Menarini Farma Ind | Composizioni farmaceutiche contenenti vitamina d e calcio,loro preparazione ed uso terapeutico |
DE19822036A1 (de) * | 1998-05-15 | 1999-11-18 | Bayer Ag | Brausezubereitungen |
GB9825033D0 (en) * | 1998-11-13 | 1999-01-13 | Nycomed Pharma As | Process |
JP4109797B2 (ja) * | 1999-06-07 | 2008-07-02 | 株式会社ロッテ | チューインガム |
DE19927537A1 (de) | 1999-06-16 | 2000-12-21 | Merck Patent Gmbh | Sprühtrocknungsanlage und Verfahren zu ihrer Verwendung |
IL150030A0 (en) * | 1999-12-09 | 2002-12-01 | Boots Co Plc | Therapeutic agents |
GB0003782D0 (en) | 2000-02-17 | 2000-04-05 | Dumex Ltd As | Process |
ATE307875T1 (de) | 2000-02-18 | 2005-11-15 | Glatt Ingtech Gmbh | Verfahren zur herstellung von vollwaschmitteln und vollwaschmittelkomponenten |
AR028064A1 (es) | 2000-05-03 | 2003-04-23 | Omnia Fertilizer Ltd | Metodo para producir granulos de nitrato de calcio |
JP2001316249A (ja) | 2000-05-11 | 2001-11-13 | Lion Corp | 錠剤型医薬組成物 |
CN1494434A (zh) | 2001-03-06 | 2004-05-05 | Э�ͷ���ҵ��ʽ���� | 含糖醇喷雾干燥粉末的用途 |
US20040071772A1 (en) | 2001-03-06 | 2004-04-15 | Shoichi Narita | Preparations quickly disintegrating in oral cavity |
ES2268020T3 (es) * | 2001-05-10 | 2007-03-16 | Astellas Pharma Inc. | Comprimidos de disgregacion rapida de la cavidad oral y proceso para producir los mismos. |
ES2192136B1 (es) | 2002-01-04 | 2005-03-16 | Italfarmaco, S.A. | Composiciones farmaceuticas para el tratamiento o prevencion de la osteoporosis. |
EP1490031A1 (en) * | 2002-03-07 | 2004-12-29 | Vectura Limited | Fast melt multiparticulate formulations for oral delivery |
DE20216314U1 (de) | 2002-10-22 | 2003-12-04 | Dhw Deutsche Hydrierwerke Gmbh Rodleben | Sprühgetrockneter Xylitol und aus diesem hergestellte Komprimate |
-
2006
- 2006-02-02 DE DE602006001295T patent/DE602006001295D1/de active Active
- 2006-02-02 ES ES06710305T patent/ES2306431T3/es active Active
- 2006-02-02 WO PCT/IB2006/000188 patent/WO2006082499A1/en active Application Filing
- 2006-02-02 EP EP06710305A patent/EP1845949B1/en not_active Not-in-force
- 2006-02-02 AT AT06710305T patent/ATE395908T1/de not_active IP Right Cessation
- 2006-02-02 US US11/883,532 patent/US8846088B2/en not_active Expired - Fee Related
- 2006-02-02 JP JP2007553727A patent/JP5224820B2/ja not_active Expired - Fee Related
- 2006-02-02 EA EA200701650A patent/EA010751B1/ru not_active IP Right Cessation
- 2006-02-02 CA CA2601755A patent/CA2601755C/en not_active Expired - Fee Related
-
2007
- 2007-09-03 NO NO20074481A patent/NO20074481L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
US20090068268A1 (en) | 2009-03-12 |
WO2006082499A1 (en) | 2006-08-10 |
CA2601755C (en) | 2014-07-29 |
EA010751B1 (ru) | 2008-10-30 |
ATE395908T1 (de) | 2008-06-15 |
US8846088B2 (en) | 2014-09-30 |
JP2008528675A (ja) | 2008-07-31 |
EP1845949A1 (en) | 2007-10-24 |
EP1845949B1 (en) | 2008-05-21 |
JP5224820B2 (ja) | 2013-07-03 |
CA2601755A1 (en) | 2006-08-10 |
ES2306431T3 (es) | 2008-11-01 |
NO20074481L (no) | 2007-11-02 |
DE602006001295D1 (de) | 2008-07-03 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
MM4A | Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s) |
Designated state(s): AM AZ BY KZ KG MD TJ TM |
|
PD4A | Registration of transfer of a eurasian patent in accordance with the succession in title | ||
MM4A | Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s) |
Designated state(s): RU |