EA200700876A1 - Агенты, специфически связывающие ангиопоэтин-2 - Google Patents
Агенты, специфически связывающие ангиопоэтин-2Info
- Publication number
- EA200700876A1 EA200700876A1 EA200700876A EA200700876A EA200700876A1 EA 200700876 A1 EA200700876 A1 EA 200700876A1 EA 200700876 A EA200700876 A EA 200700876A EA 200700876 A EA200700876 A EA 200700876A EA 200700876 A1 EA200700876 A1 EA 200700876A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- angiopoetin
- specifically binding
- agents specifically
- antibodies
- fragments
- Prior art date
Links
Landscapes
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Раскрыты специфические связывающие агенты, такие как полностью человеческие антитела, которые связывают ангиопоэтин-2. Раскрыты также фрагменты тяжёлых цепей, фрагменты лёгких цепей и участки, определяющие комплементарность (CDR), в составе антител, а также способы получения и применения этих антител.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US62016104P | 2004-10-19 | 2004-10-19 | |
US10/982,440 US7658924B2 (en) | 2001-10-11 | 2004-11-04 | Angiopoietin-2 specific binding agents |
PCT/US2005/037911 WO2006045049A1 (en) | 2004-10-19 | 2005-10-19 | Angiopoietin-2 specific binding agents |
Publications (2)
Publication Number | Publication Date |
---|---|
EA200700876A1 true EA200700876A1 (ru) | 2007-10-26 |
EA011866B1 EA011866B1 (ru) | 2009-06-30 |
Family
ID=39608222
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EA200700876A EA011866B1 (ru) | 2004-10-19 | 2005-10-19 | Агенты, специфически связывающие ангиопоэтин-2 |
Country Status (10)
Country | Link |
---|---|
JP (2) | JP2008520188A (ru) |
CN (1) | CN101495513B (ru) |
BR (1) | BRPI0518209A (ru) |
EA (1) | EA011866B1 (ru) |
IL (1) | IL182279A0 (ru) |
MA (1) | MA29015B1 (ru) |
MX (1) | MX2007004247A (ru) |
RU (2) | RU2404992C2 (ru) |
SG (1) | SG156668A1 (ru) |
ZA (1) | ZA200704020B (ru) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2014100834A1 (en) * | 2012-12-21 | 2014-06-26 | The Regents Of The University Of California | Methods and compositions for treatment of cyanide and hydrogen sulfide toxicity |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2008520188A (ja) * | 2004-10-19 | 2008-06-19 | アムジエン・インコーポレーテツド | アンジオポエチン−2特異的結合物質 |
JO3182B1 (ar) * | 2009-07-29 | 2018-03-08 | Regeneron Pharma | مضادات حيوية بشرية عالية الالفة مع تولد الاوعية البشرية - 2 |
EA022546B1 (ru) * | 2011-09-28 | 2016-01-29 | Федеральное Государственное Бюджетное Учреждение Науки Институт Биоорганической Химии Им. Академиков М.М. Шемякина И Ю.А. Овчинникова Российской Академии Наук | Способ торможения роста карциномы эрлиха у лабораторного животного |
JP2014532053A (ja) * | 2011-09-30 | 2014-12-04 | デイナ ファーバー キャンサー インスティチュート,インコーポレイテッド | 治療用ペプチド |
WO2013112438A1 (en) * | 2012-01-23 | 2013-08-01 | Regeneron Pharmaceuticals, Inc. | Stabilized formulations containing anti-ang2 antibodies |
MX368099B (es) * | 2013-05-14 | 2019-09-19 | Eisai R&D Man Co Ltd | Biomarcadores para predecir y evaluar el grado de respuesta de sujetos con cancer de endometrio a compuestos de tipo lenvatinib. |
AR100270A1 (es) * | 2014-05-19 | 2016-09-21 | Lilly Co Eli | Anticuerpos ang2 |
KR102329681B1 (ko) | 2014-08-28 | 2021-11-23 | 에자이 알앤드디 매니지먼트 가부시키가이샤 | 고순도의 퀴놀린 유도체 및 이를 제조하는 방법 |
BR112017017428A2 (pt) | 2015-02-25 | 2018-04-03 | Eisai R&D Management Co., Ltd. | ?método para supressão do amargor de derivado de quinolina? |
CA2978226A1 (en) | 2015-03-04 | 2016-09-09 | Merck Sharpe & Dohme Corp. | Combination of a pd-1 antagonist and a vegfr/fgfr/ret tyrosine kinase inhibitor for treating cancer |
BR112017027227B1 (pt) | 2015-06-16 | 2023-12-12 | Eisai R&D Management Co., Ltd | Agente anti-câncer |
CN106075448A (zh) * | 2016-07-25 | 2016-11-09 | 广州道瑞医药科技有限公司 | Angpt2抑制剂在制备用于治疗血管瘤的药物中的应用 |
CN106512006A (zh) * | 2016-07-25 | 2017-03-22 | 广州道瑞医药科技有限公司 | Angpt2分泌抑制剂在制备用于治疗血管瘤的药物中的应用 |
CN109096368B (zh) * | 2018-09-30 | 2021-07-20 | 华南理工大学 | 一种同时具有抗氧化和护肝活性的多肽及编码该多肽的基因与其制备方法和应用 |
KR102527315B1 (ko) * | 2019-02-25 | 2023-05-03 | 주식회사 파멥신 | 항-Ang2 항체 및 이의 용도 |
CN112126671B (zh) * | 2020-08-18 | 2021-08-31 | 中山大学附属第五医院 | 无乳链球菌Streptococus agalactiae治疗子宫内膜异位症的应用 |
CN116265487A (zh) * | 2021-12-16 | 2023-06-20 | 三优生物医药(上海)有限公司 | 抗ang2-vegf双特异性抗体及其用途 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2002540165A (ja) * | 1999-03-26 | 2002-11-26 | リジェネロン・ファーマシューティカルズ・インコーポレイテッド | Tie2レセプターアクチベーターによる血管透過性の調節 |
US7205275B2 (en) * | 2001-10-11 | 2007-04-17 | Amgen Inc. | Methods of treatment using specific binding agents of human angiopoietin-2 |
US7521053B2 (en) * | 2001-10-11 | 2009-04-21 | Amgen Inc. | Angiopoietin-2 specific binding agents |
CA2473970C (en) * | 2001-10-12 | 2013-05-28 | Monosolrx Llc | Uniform films for rapid dissolve dosage form incorporating taste-masking compositions |
JP2008520188A (ja) * | 2004-10-19 | 2008-06-19 | アムジエン・インコーポレーテツド | アンジオポエチン−2特異的結合物質 |
-
2005
- 2005-10-19 JP JP2007538066A patent/JP2008520188A/ja active Pending
- 2005-10-19 CN CN200580043569.5A patent/CN101495513B/zh not_active Expired - Fee Related
- 2005-10-19 EA EA200700876A patent/EA011866B1/ru not_active IP Right Cessation
- 2005-10-19 BR BRPI0518209-3A patent/BRPI0518209A/pt not_active IP Right Cessation
- 2005-10-19 SG SG200907008-7A patent/SG156668A1/en unknown
- 2005-10-19 RU RU2007118670/13A patent/RU2404992C2/ru not_active IP Right Cessation
- 2005-10-19 MX MX2007004247A patent/MX2007004247A/es active IP Right Grant
-
2007
- 2007-03-28 IL IL182279A patent/IL182279A0/en unknown
- 2007-05-11 MA MA29892A patent/MA29015B1/fr unknown
- 2007-05-18 ZA ZA200704020A patent/ZA200704020B/en unknown
-
2010
- 2010-08-05 RU RU2010132956/10A patent/RU2010132956A/ru not_active Application Discontinuation
-
2011
- 2011-03-30 JP JP2011075243A patent/JP2011207882A/ja not_active Withdrawn
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2014100834A1 (en) * | 2012-12-21 | 2014-06-26 | The Regents Of The University Of California | Methods and compositions for treatment of cyanide and hydrogen sulfide toxicity |
US9534007B2 (en) | 2012-12-21 | 2017-01-03 | The Regents Of The University Of California | Methods and compositions for treatment of cyanide and hydrogen sulfide toxicity |
Also Published As
Publication number | Publication date |
---|---|
RU2007118670A (ru) | 2008-12-27 |
CN101495513B (zh) | 2014-08-06 |
EA011866B1 (ru) | 2009-06-30 |
MA29015B1 (fr) | 2007-11-01 |
CN101495513A (zh) | 2009-07-29 |
JP2008520188A (ja) | 2008-06-19 |
SG156668A1 (en) | 2009-11-26 |
IL182279A0 (en) | 2007-07-24 |
ZA200704020B (en) | 2008-06-25 |
JP2011207882A (ja) | 2011-10-20 |
MX2007004247A (es) | 2007-06-12 |
BRPI0518209A (pt) | 2008-11-04 |
RU2404992C2 (ru) | 2010-11-27 |
RU2010132956A (ru) | 2012-02-10 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
MM4A | Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s) |
Designated state(s): AM AZ BY KZ KG MD TJ TM |
|
MM4A | Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s) |
Designated state(s): RU |