EA200700255A1 - Новый карбамилированный еро и способ его получения - Google Patents
Новый карбамилированный еро и способ его полученияInfo
- Publication number
- EA200700255A1 EA200700255A1 EA200700255A EA200700255A EA200700255A1 EA 200700255 A1 EA200700255 A1 EA 200700255A1 EA 200700255 A EA200700255 A EA 200700255A EA 200700255 A EA200700255 A EA 200700255A EA 200700255 A1 EA200700255 A1 EA 200700255A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- carbamilated
- epo
- obtaining
- new
- carbamylated erythropoietin
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/505—Erythropoietin [EPO]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1816—Erythropoietin [EPO]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Toxicology (AREA)
- Hospice & Palliative Care (AREA)
- Urology & Nephrology (AREA)
- Biochemistry (AREA)
- Psychology (AREA)
- Psychiatry (AREA)
- Molecular Biology (AREA)
- Vascular Medicine (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
В настоящем изобретении описан способ получения нового карбамилированного эритропоэтина и содержащих новый карбамилированный эритропоэтин композиций, и содержащих его фармацевтических композиций, и их применение.
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US58637004P | 2004-07-07 | 2004-07-07 | |
DKPA200401075 | 2004-07-07 | ||
US69387005P | 2005-06-23 | 2005-06-23 | |
PCT/DK2005/000477 WO2006002646A2 (en) | 2004-07-07 | 2005-07-07 | Novel carbamylated epo and method for its production |
Publications (2)
Publication Number | Publication Date |
---|---|
EA200700255A1 true EA200700255A1 (ru) | 2007-06-29 |
EA011586B1 EA011586B1 (ru) | 2009-04-28 |
Family
ID=34979159
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EA200700255A EA011586B1 (ru) | 2004-07-07 | 2005-07-07 | Новый карбамилированный еро и способ его получения |
Country Status (20)
Country | Link |
---|---|
EP (1) | EP1781697B1 (ru) |
JP (1) | JP5025470B2 (ru) |
AT (1) | ATE429444T1 (ru) |
AU (1) | AU2005259689B2 (ru) |
BR (1) | BRPI0513029A (ru) |
CA (1) | CA2572643A1 (ru) |
CY (1) | CY1109232T1 (ru) |
DE (1) | DE602005014117D1 (ru) |
DK (1) | DK1781697T3 (ru) |
EA (1) | EA011586B1 (ru) |
ES (1) | ES2325034T3 (ru) |
HK (1) | HK1109631A1 (ru) |
HR (1) | HRP20090343T1 (ru) |
IL (1) | IL180518A0 (ru) |
MX (1) | MXPA06014742A (ru) |
NO (1) | NO20070687L (ru) |
PL (1) | PL1781697T3 (ru) |
PT (1) | PT1781697E (ru) |
SI (1) | SI1781697T1 (ru) |
WO (1) | WO2006002646A2 (ru) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
RU2720103C1 (ru) * | 2019-10-16 | 2020-04-24 | Федеральное государственное автономное образовательное учреждение высшего образования "Белгородский государственный национальный исследовательский университет" (НИУ "БелГУ") | Способ коррекции нарушений микроциркуляции в плаценте карбамилированным дарбэпоэтином при ADMA-подобной модели преэклампсии |
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US7718363B2 (en) | 2003-04-25 | 2010-05-18 | The Kenneth S. Warren Institute, Inc. | Tissue protective cytokine receptor complex and assays for identifying tissue protective compounds |
EP1771190A4 (en) * | 2004-07-02 | 2009-07-22 | Kenneth S Warren Inst Inc | METHOD FOR THE PRODUCTION OF COMPLETELY CARBAMYLATED ERYTHROPOIETIN |
DE102006004008A1 (de) * | 2006-01-27 | 2007-08-02 | Hannelore Prof. Dr. Dr. Ehrenreich | Verfahren zur Behandlung und/oder Prophylaxe von Multipler Sklerose, sowie Verwendung von Erythropoietin zur Herstellung eines Arzneimittels zur intermittierenden Behandlung und/oder intermittierenden Prophylaxe von Multipler Sklerose |
US7811560B2 (en) * | 2006-01-30 | 2010-10-12 | Auxilium Us Holdings, Llc | Compositions and methods for treating collagen-mediated diseases |
ES2327170T3 (es) * | 2007-02-22 | 2009-10-26 | Polymun Scientific Immunbiologische Forschung Gmbh | Proteina de fusion de eritropoyetina. |
AR065613A1 (es) * | 2007-03-09 | 2009-06-17 | Chugai Pharmaceutical Co Ltd | Agentes de proteccion para organos transplantados |
ES2750254T3 (es) | 2007-09-27 | 2020-03-25 | Amgen Inc | Formulaciones farmacéuticas |
WO2009064838A1 (en) | 2007-11-15 | 2009-05-22 | Amgen, Inc. | Aqueous formulation of erythropoiesis stimulating protein stablised by antioxidants for parenteral administration |
EP2803675A3 (en) | 2008-01-25 | 2014-12-24 | Amgen, Inc | Ferroportin antibodies and methods of use |
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WO2010056981A2 (en) | 2008-11-13 | 2010-05-20 | Massachusetts General Hospital | Methods and compositions for regulating iron homeostasis by modulation bmp-6 |
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TW201129374A (en) | 2009-10-26 | 2011-09-01 | Lundbeck & Co As H | Use of carbamylated erythropoietin for the treatment of Friedreich's ataxia |
TW201129375A (en) | 2009-11-18 | 2011-09-01 | Lundbeck & Co As H | Treatment of acute ischemic stroke or intracranial bleeding with tPa and carbamylated erythropoietin |
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Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
RU2215748C2 (ru) * | 1999-04-09 | 2003-11-10 | Сентро Де Инмунология Молекулар | Способ получения рекомбинантного эритропоэтина человека и полученный эритропоэтин, фармацевтическая композиция |
PA8536201A1 (es) * | 2000-12-29 | 2002-08-29 | Kenneth S Warren Inst Inc | Protección y mejoramiento de células, tejidos y órganos que responden a la eritropoyetina |
US20030072737A1 (en) * | 2000-12-29 | 2003-04-17 | Michael Brines | Tissue protective cytokines for the protection, restoration, and enhancement of responsive cells, tissues and organs |
EP1633305A2 (en) * | 2003-05-19 | 2006-03-15 | The Kenneth S. Warren Institute, Inc. | Tissue protective cytokines for the protection, restoration, and enhancement of responsive cells, tissues and organs with an extended therapeutic window |
-
2005
- 2005-07-07 EA EA200700255A patent/EA011586B1/ru not_active IP Right Cessation
- 2005-07-07 DK DK05755533T patent/DK1781697T3/da active
- 2005-07-07 AT AT05755533T patent/ATE429444T1/de active
- 2005-07-07 PL PL05755533T patent/PL1781697T3/pl unknown
- 2005-07-07 AU AU2005259689A patent/AU2005259689B2/en not_active Ceased
- 2005-07-07 WO PCT/DK2005/000477 patent/WO2006002646A2/en active Application Filing
- 2005-07-07 EP EP05755533A patent/EP1781697B1/en active Active
- 2005-07-07 CA CA002572643A patent/CA2572643A1/en not_active Abandoned
- 2005-07-07 DE DE602005014117T patent/DE602005014117D1/de active Active
- 2005-07-07 BR BRPI0513029-8A patent/BRPI0513029A/pt not_active IP Right Cessation
- 2005-07-07 MX MXPA06014742A patent/MXPA06014742A/es active IP Right Grant
- 2005-07-07 SI SI200530707T patent/SI1781697T1/sl unknown
- 2005-07-07 JP JP2007519619A patent/JP5025470B2/ja not_active Expired - Fee Related
- 2005-07-07 ES ES05755533T patent/ES2325034T3/es active Active
- 2005-07-07 PT PT05755533T patent/PT1781697E/pt unknown
-
2007
- 2007-01-02 IL IL180518A patent/IL180518A0/en unknown
- 2007-02-06 NO NO20070687A patent/NO20070687L/no not_active Application Discontinuation
-
2008
- 2008-01-10 HK HK08100325.8A patent/HK1109631A1/xx not_active IP Right Cessation
-
2009
- 2009-06-15 HR HR20090343T patent/HRP20090343T1/xx unknown
- 2009-07-14 CY CY20091100734T patent/CY1109232T1/el unknown
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
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RU2720103C1 (ru) * | 2019-10-16 | 2020-04-24 | Федеральное государственное автономное образовательное учреждение высшего образования "Белгородский государственный национальный исследовательский университет" (НИУ "БелГУ") | Способ коррекции нарушений микроциркуляции в плаценте карбамилированным дарбэпоэтином при ADMA-подобной модели преэклампсии |
Also Published As
Publication number | Publication date |
---|---|
EA011586B1 (ru) | 2009-04-28 |
AU2005259689A1 (en) | 2006-01-12 |
JP5025470B2 (ja) | 2012-09-12 |
PT1781697E (pt) | 2009-06-25 |
MXPA06014742A (es) | 2007-02-16 |
CY1109232T1 (el) | 2014-07-02 |
DK1781697T3 (da) | 2009-07-06 |
WO2006002646A2 (en) | 2006-01-12 |
CA2572643A1 (en) | 2006-01-12 |
PL1781697T3 (pl) | 2009-10-30 |
HK1109631A1 (en) | 2008-06-13 |
JP2008505133A (ja) | 2008-02-21 |
IL180518A0 (en) | 2007-06-03 |
NO20070687L (no) | 2007-03-27 |
BRPI0513029A (pt) | 2008-04-22 |
WO2006002646A3 (en) | 2006-04-13 |
ATE429444T1 (de) | 2009-05-15 |
AU2005259689B2 (en) | 2011-10-06 |
EP1781697B1 (en) | 2009-04-22 |
HRP20090343T1 (en) | 2009-07-31 |
EP1781697A2 (en) | 2007-05-09 |
SI1781697T1 (sl) | 2009-08-31 |
ES2325034T3 (es) | 2009-08-24 |
DE602005014117D1 (de) | 2009-06-04 |
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