DK488885A - 9-amino-1,2,3,4-tetrahydroacridin-1-ol og beslaegtede forbindelser, enfremgangsmaade til deres fremstilling og deres anvendelse som laegemidler - Google Patents

9-amino-1,2,3,4-tetrahydroacridin-1-ol og beslaegtede forbindelser, enfremgangsmaade til deres fremstilling og deres anvendelse som laegemidler Download PDF

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Publication number
DK488885A
DK488885A DK488885A DK488885A DK488885A DK 488885 A DK488885 A DK 488885A DK 488885 A DK488885 A DK 488885A DK 488885 A DK488885 A DK 488885A DK 488885 A DK488885 A DK 488885A
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DK
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Prior art keywords
tetrahydroacridin
medicines
procedures
amino
preparation
Prior art date
Application number
DK488885A
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English (en)
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DK167250B1 (da
DK488885D0 (da
Inventor
Gregory M Shutske
Frank A Pierrat
Original Assignee
Hoechst Roussel Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/664,731 external-priority patent/US4631286A/en
Priority claimed from US06/781,155 external-priority patent/US4695573A/en
Application filed by Hoechst Roussel Pharma filed Critical Hoechst Roussel Pharma
Publication of DK488885D0 publication Critical patent/DK488885D0/da
Publication of DK488885A publication Critical patent/DK488885A/da
Application granted granted Critical
Publication of DK167250B1 publication Critical patent/DK167250B1/da

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D219/00—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
    • C07D219/04—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
    • C07D219/08—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D219/00—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
    • C07D219/04—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
    • C07D219/08—Nitrogen atoms
    • C07D219/10—Nitrogen atoms attached in position 9
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D219/00—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
    • C07D219/04—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
    • C07D219/08—Nitrogen atoms
    • C07D219/10—Nitrogen atoms attached in position 9
    • C07D219/12—Amino-alkylamino radicals attached in position 9
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/04—Ortho- or peri-condensed ring systems
    • C07D221/06—Ring systems of three rings
    • C07D221/16—Ring systems of three rings containing carbocyclic rings other than six-membered

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
DK488885A 1984-10-25 1985-10-24 9-amino-acridinderivater, fremgangsmaade til deres fremstilling, farmaceutiske praeparater deraf og deres anvendelse til fremstilling af laegemidler DK167250B1 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US06/664,731 US4631286A (en) 1984-10-25 1984-10-25 9-amino-1,2,3,4-tetrahydroacridin-1-ol and related compounds
US66473184 1984-10-25
US06/781,155 US4695573A (en) 1984-10-25 1985-10-01 9-amino-1,2,3,4-tetrahydroacridin-1-ol and related compounds
US78115585 1985-10-01

Publications (3)

Publication Number Publication Date
DK488885D0 DK488885D0 (da) 1985-10-24
DK488885A true DK488885A (da) 1986-04-26
DK167250B1 DK167250B1 (da) 1993-09-27

Family

ID=27099040

Family Applications (2)

Application Number Title Priority Date Filing Date
DK488885A DK167250B1 (da) 1984-10-25 1985-10-24 9-amino-acridinderivater, fremgangsmaade til deres fremstilling, farmaceutiske praeparater deraf og deres anvendelse til fremstilling af laegemidler
DK141992A DK168704B1 (da) 1984-10-25 1992-11-26 N-(3-Oxocyclohexen-1-yl)-2-aminobenzonitrilderivater

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK141992A DK168704B1 (da) 1984-10-25 1992-11-26 N-(3-Oxocyclohexen-1-yl)-2-aminobenzonitrilderivater

Country Status (20)

Country Link
US (1) US4839364A (da)
EP (1) EP0179383B1 (da)
JP (1) JPH01125362A (da)
KR (1) KR900007624B1 (da)
AR (1) AR247394A1 (da)
AT (1) ATE63903T1 (da)
AU (2) AU589141B2 (da)
CA (1) CA1292744C (da)
DE (1) DE3582995D1 (da)
DK (2) DK167250B1 (da)
ES (3) ES8701165A1 (da)
FI (1) FI86421C (da)
GR (1) GR852555B (da)
HU (1) HU196183B (da)
IE (1) IE58696B1 (da)
IL (3) IL90300A (da)
NO (1) NO172847C (da)
NZ (2) NZ213932A (da)
PH (1) PH22614A (da)
PT (1) PT81362B (da)

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US4916135A (en) * 1989-05-08 1990-04-10 Hoechst Roussel Pharmaceuticals Inc. N-heteroaryl-4-quinolinamines
US5053513A (en) * 1990-03-29 1991-10-01 Hoechst-Roussel Pharmaceuticals Incorporated Method of reducing a carbonyl containing acridine
US5210087A (en) * 1991-02-13 1993-05-11 Hoechst-Roussel Pharmaceuticals Inc. 9-aminotetrahydroacridines and related compounds
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US5434170A (en) * 1993-12-23 1995-07-18 Andrulis Pharmaceuticals Corp. Method for treating neurocognitive disorders
US20100210590A1 (en) * 1995-09-27 2010-08-19 Northwestern University Compositions and treatments for seizure-related disorders
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KR100381716B1 (ko) * 2000-10-09 2003-04-26 한국화학연구원 항암활성을 가지는 아크리딘 유도체
US20050222123A1 (en) 2004-01-27 2005-10-06 North Shore-Long Island Jewish Research Institute Cholinesterase inhibitors for treating inflammation
WO2006004201A1 (ja) * 2004-07-01 2006-01-12 Eisai R & D Management Co., Ltd. 神経再生促進剤
WO2006050359A2 (en) * 2004-11-02 2006-05-11 Northwestern University Pyridazine compounds and methods
WO2006059252A2 (en) * 2004-11-12 2006-06-08 Neurochem (International) Limited Methods and fluorinated compositions for treating amyloid-related diseases
US20080188510A1 (en) * 2005-05-23 2008-08-07 Eisai R & D Management Co., Ltd. Novel methods using zonisamide
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AU2015205995A1 (en) * 2014-01-15 2016-07-28 Centre National De La Recherche Scientifique (Cnrs) Water soluble 4-azapodophyllotoxin analogs
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Also Published As

Publication number Publication date
DK167250B1 (da) 1993-09-27
AU615768B2 (en) 1991-10-10
JPH0584306B2 (da) 1993-12-01
GR852555B (da) 1986-02-24
AU3823489A (en) 1989-10-26
FI854156A0 (fi) 1985-10-23
AU4903885A (en) 1986-05-01
NZ213932A (en) 1990-12-21
CA1292744C (en) 1991-12-03
FI86421B (fi) 1992-05-15
HUT41009A (en) 1987-03-30
PT81362B (pt) 1987-11-30
KR860003227A (ko) 1986-05-21
US4839364A (en) 1989-06-13
EP0179383B1 (en) 1991-05-29
NZ229248A (en) 1990-12-21
DK168704B1 (da) 1994-05-24
FI86421C (fi) 1992-08-25
IE852632L (en) 1986-04-25
DK141992A (da) 1992-11-26
ES8701165A1 (es) 1986-11-16
ES8802383A1 (es) 1988-05-16
NO172847C (no) 1993-09-15
DK488885D0 (da) 1985-10-24
NO904711L (no) 1986-04-28
IL76796A (en) 1990-03-19
ES8801213A1 (es) 1988-01-01
JPH01125362A (ja) 1989-05-17
KR900007624B1 (ko) 1990-10-17
PT81362A (en) 1985-11-01
IL90300A (en) 1990-11-29
IE58696B1 (en) 1993-11-03
HU196183B (en) 1988-10-28
DK141992D0 (da) 1992-11-26
AU589141B2 (en) 1989-10-05
ES554569A0 (es) 1988-01-01
ATE63903T1 (de) 1991-06-15
ES554568A0 (es) 1988-05-16
EP0179383A2 (en) 1986-04-30
NO904711D0 (no) 1990-10-30
IL76796A0 (en) 1986-02-28
PH22614A (en) 1988-10-17
IL90300A0 (en) 1989-12-15
NO172847B (no) 1993-06-07
AR247394A1 (es) 1994-12-29
DE3582995D1 (de) 1991-07-04
ES548137A0 (es) 1986-11-16
EP0179383A3 (en) 1987-01-28
FI854156L (fi) 1986-04-26

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