DK440686A - Antipsykotisk virksomme gamma-carboliner - Google Patents

Antipsykotisk virksomme gamma-carboliner Download PDF

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Publication number
DK440686A
DK440686A DK440686A DK440686A DK440686A DK 440686 A DK440686 A DK 440686A DK 440686 A DK440686 A DK 440686A DK 440686 A DK440686 A DK 440686A DK 440686 A DK440686 A DK 440686A
Authority
DK
Denmark
Prior art keywords
cycotic
effective gamma
carbolines
gamma carbolines
effective
Prior art date
Application number
DK440686A
Other languages
Danish (da)
English (en)
Other versions
DK440686D0 (da
Inventor
Magid Abdel-Megid Abou-Gharbia
Original Assignee
American Home Prod
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Home Prod filed Critical American Home Prod
Publication of DK440686D0 publication Critical patent/DK440686D0/da
Publication of DK440686A publication Critical patent/DK440686A/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Psychiatry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK440686A 1985-09-16 1986-09-15 Antipsykotisk virksomme gamma-carboliner DK440686A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/776,180 US4636563A (en) 1985-09-16 1985-09-16 Antipsychotic γ-carbolines

Publications (2)

Publication Number Publication Date
DK440686D0 DK440686D0 (da) 1986-09-15
DK440686A true DK440686A (da) 1987-03-17

Family

ID=25106686

Family Applications (1)

Application Number Title Priority Date Filing Date
DK440686A DK440686A (da) 1985-09-16 1986-09-15 Antipsykotisk virksomme gamma-carboliner

Country Status (28)

Country Link
US (1) US4636563A (pt)
EP (1) EP0223344B1 (pt)
JP (1) JPS6267083A (pt)
KR (1) KR900002245B1 (pt)
CN (1) CN1013864B (pt)
AR (1) AR242208A1 (pt)
AT (1) ATE55770T1 (pt)
AU (1) AU590605B2 (pt)
CA (1) CA1275099A (pt)
CY (1) CY1595A (pt)
DE (1) DE3673607D1 (pt)
DK (1) DK440686A (pt)
EG (1) EG18015A (pt)
ES (1) ES2002656A6 (pt)
FI (1) FI83318C (pt)
GB (1) GB2180536B (pt)
GR (1) GR862343B (pt)
HK (1) HK53491A (pt)
HU (1) HU195217B (pt)
IL (1) IL79956A0 (pt)
MX (1) MX3681A (pt)
NO (1) NO163619C (pt)
NZ (1) NZ217580A (pt)
PH (1) PH22515A (pt)
PT (1) PT83344B (pt)
SU (1) SU1442074A3 (pt)
YU (1) YU45023B (pt)
ZA (1) ZA866258B (pt)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5328905A (en) * 1987-07-20 1994-07-12 Duphar International Research B.V. 8,9-anellated-1,2,3,4-tetrahydro-β-carboline derivatives
US5360800A (en) * 1987-09-03 1994-11-01 Glaxo Group Limited Tetrahydro-1H-pyrido[4,3-b]indol-1-one derivatives
US4798896A (en) * 1988-01-19 1989-01-17 American Home Products Corporation Antipsychotic gamma-carboline N-oxides
HU207078B (en) * 1988-08-02 1993-03-01 Glaxo Group Ltd Process for producing lactam derivatives and pharmaceutical compositions comprising such compounds
US5008272A (en) * 1988-08-15 1991-04-16 Glaxo Group Limited Lactam derivatives
US5021569A (en) * 1990-06-12 1991-06-04 American Home Products Corporation 4-azatricyclo[4.3.1.1(3,8)]undecylarylpiperazines with anxiolytic activity
US5631017A (en) * 1993-03-26 1997-05-20 Beth Israel Deaconess Medical Center, Inc. Topical application of buspirone for treatment of pathological conditions associated with immune responses
US5484788A (en) * 1993-03-26 1996-01-16 Beth Israel Hospital Association Buspirone as a systemic immunosuppressant
CN1109880A (zh) * 1994-02-03 1995-10-11 合成实验室公司 3-(2-氨基乙基)-4-[3-(三氟甲基)苯甲酰基]-3，4-二氢-2h-1，4-苯并噁嗪衍生物、制备及其应用
FR2715659B1 (fr) * 1994-02-03 1996-03-22 Synthelabo Dérivés de 3-(2-aminoéthyl)-4-[3-(trifluorométhyl)benzoyl]-3,4-dihydro-2H-1,4-benzoxazine, leur préparation et leur application en thérapeutique.
JP3274579B2 (ja) * 1995-01-12 2002-04-15 住友製薬株式会社 脳血管障害に伴う精神症候治療剤
US5637314A (en) * 1995-06-07 1997-06-10 Beth Israel Deaconess Medical Center, Inc. Topical and systemic application of buspirone or derivatives thereof for treating atopic dermatitis
RU2106864C1 (ru) * 1995-10-23 1998-03-20 Николай Серафимович Зефиров Средство для лечения болезни альцгеймера
RU2283108C2 (ru) * 2003-12-08 2006-09-10 Сергей Олегович Бачурин ГЕРОПРОТЕКТОР НА ОСНОВЕ ГИДРИРОВАННЫХ ПИРИДО(4,3-b) ИНДОЛОВ (ВАРИАНТЫ), ФАРМАКОЛОГИЧЕСКОЕ СРЕДСТВО НА ЕГО ОСНОВЕ И СПОСОБ ЕГО ПРИМЕНЕНИЯ
US20070179174A1 (en) * 2003-12-08 2007-08-02 Bachurin Sergei O Methods and compositions for slowing aging
EA200800430A1 (ru) * 2005-07-28 2008-06-30 Бристол-Маерс Сквибб Компани Замещённые тетрагидро-1н-пиридо[4,3,b] индолы как агонисты и антагонисты серотониновых рецепторов
WO2007041697A2 (en) * 2005-10-04 2007-04-12 Medivation, Inc. Hydrogenated pyrido-indole compounds for the treatment of huntington ' s disease
RU2338537C2 (ru) * 2006-01-25 2008-11-20 Сергей Олегович Бачурин СРЕДСТВО ДЛЯ ЛЕЧЕНИЯ ШИЗОФРЕНИИ НА ОСНОВЕ ГИДРИРОВАННЫХ ПИРИДО(4,3-b)ИНДОЛОВ (ВАРИАНТЫ), ФАРМАКОЛОГИЧЕСКОЕ СРЕДСТВО НА ЕГО ОСНОВЕ И СПОСОБ ЕГО ПРИМЕНЕНИЯ

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1670010A1 (de) * 1966-12-07 1970-07-30 Abbott Lab Aroylalkylderivate von 1,2,3,4-Tetrahydro-5H-pyride-[4,3b]-indolen und Verfahren zur Herstellung derselben
US3502688A (en) * 1968-09-10 1970-03-24 Hoffmann La Roche 5-(4-pyridylethyl)-pyridoindole derivatives
US3522262A (en) * 1968-09-10 1970-07-28 Hoffmann La Roche 5-(pyridylalkyl)-pyridoindole derivatives
DE1952800C3 (de) * 1969-10-20 1974-04-18 Nautschno-Issledowatelskij Institut Farmakologii I Chimioterapii, Moskau 3,6-Dimethyl-l,2,3,4,4a,9a-hexahydro-gamma-carbolin-dihydrochlorid
US4001263A (en) * 1974-04-01 1977-01-04 Pfizer Inc. 5-Aryl-1,2,3,4-tetrahydro-γ-carbolines
DE2621729A1 (de) * 1976-05-15 1977-12-08 Boehringer Sohn Ingelheim Neue 2-(4-phenyl-4-cyanobutyl)-1,2, 3,4-tetrahydro-5(h)-pyrido- eckige klammer auf 4,3-b eckige klammer zu -indole und verfahren zu ihrer herstellung
US4224329A (en) * 1979-01-23 1980-09-23 Pfizer Inc. 2-Substituted-trans-5-aryl-2,3,4,4a,5,9b-hexahydro-1H-pyrido[4,3-b]indoles
US4337250A (en) * 1979-07-30 1982-06-29 Pfizer Inc. Hexahydro-trans- and tetrahydropyridoindole neuroleptic agents
US4672117A (en) * 1985-09-16 1987-06-09 American Home Products Corporation Antipsychotic gamma-carbolines
IL87658A (en) * 1987-09-03 1994-06-24 Glaxo Group Ltd Tetrahydro-H-) -12-imidazolylmethyl (pyrido-) and azapino- (] B) -4,3 ([indole-1-ointments, their preparation and pharmaceutical preparations containing them

Also Published As

Publication number Publication date
NO863671L (no) 1987-03-17
NO163619C (no) 1990-06-27
PT83344A (pt) 1986-10-01
HU195217B (en) 1988-04-28
JPS6267083A (ja) 1987-03-26
GB2180536A (en) 1987-04-01
NO163619B (no) 1990-03-19
NZ217580A (en) 1988-07-28
ZA866258B (en) 1988-04-27
AR242208A1 (es) 1994-08-31
EP0223344A1 (en) 1987-05-27
CA1275099A (en) 1990-10-09
KR900002245B1 (ko) 1990-04-07
PT83344B (pt) 1988-07-29
DE3673607D1 (en) 1990-09-27
FI83318B (fi) 1991-03-15
CN1013864B (zh) 1991-09-11
FI83318C (fi) 1991-06-25
ATE55770T1 (de) 1990-09-15
HUT42478A (en) 1987-07-28
PH22515A (en) 1988-09-12
CY1595A (en) 1992-04-03
AU6181386A (en) 1987-03-19
ES2002656A6 (es) 1988-09-16
YU45023B (en) 1991-06-30
NO863671D0 (no) 1986-09-15
US4636563A (en) 1987-01-13
EP0223344B1 (en) 1990-08-22
GR862343B (en) 1987-01-12
KR870003103A (ko) 1987-04-15
MX3681A (es) 1993-10-01
HK53491A (en) 1991-07-19
GB8621226D0 (en) 1986-10-08
DK440686D0 (da) 1986-09-15
GB2180536B (en) 1989-04-05
CN86106194A (zh) 1987-03-18
EG18015A (en) 1991-08-30
AU590605B2 (en) 1989-11-09
SU1442074A3 (ru) 1988-11-30
FI863692A (fi) 1987-03-17
IL79956A0 (en) 1986-12-31
FI863692A0 (fi) 1986-09-12
YU157686A (en) 1988-04-30

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Legal Events

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AHB Application shelved due to non-payment