DK2576580T3 - LOWERING THE lactate AND INCREASE polypeptide production by downregulation of the expression of lactate dehydrogenase, and PYRUVATDEHYDROGENASEKINASE - Google Patents
LOWERING THE lactate AND INCREASE polypeptide production by downregulation of the expression of lactate dehydrogenase, and PYRUVATDEHYDROGENASEKINASE Download PDFInfo
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- DK2576580T3 DK2576580T3 DK11787435.4T DK11787435T DK2576580T3 DK 2576580 T3 DK2576580 T3 DK 2576580T3 DK 11787435 T DK11787435 T DK 11787435T DK 2576580 T3 DK2576580 T3 DK 2576580T3
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Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US34972710P | 2010-05-28 | 2010-05-28 | |
PCT/US2011/038191 WO2011150241A2 (en) | 2010-05-28 | 2011-05-26 | Decreasing lactate level and increasing polypeptide production by downregulating the expression of lactate dehydrogenase and pyruvate dehydrogenase kinase |
Publications (1)
Publication Number | Publication Date |
---|---|
DK2576580T3 true DK2576580T3 (en) | 2016-10-17 |
Family
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Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK11787435.4T DK2576580T3 (en) | 2010-05-28 | 2011-05-26 | LOWERING THE lactate AND INCREASE polypeptide production by downregulation of the expression of lactate dehydrogenase, and PYRUVATDEHYDROGENASEKINASE |
Country Status (15)
Country | Link |
---|---|
US (4) | US9487809B2 (pt) |
EP (1) | EP2576580B1 (pt) |
JP (3) | JP6050226B2 (pt) |
KR (3) | KR101869987B1 (pt) |
CN (1) | CN102985437B (pt) |
BR (1) | BR112012030197A2 (pt) |
CA (1) | CA2800728C (pt) |
DK (1) | DK2576580T3 (pt) |
ES (1) | ES2599412T3 (pt) |
HU (1) | HUE030820T2 (pt) |
MX (2) | MX343604B (pt) |
PL (1) | PL2576580T3 (pt) |
RU (1) | RU2614125C2 (pt) |
SI (1) | SI2576580T1 (pt) |
WO (1) | WO2011150241A2 (pt) |
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US9017687B1 (en) | 2013-10-18 | 2015-04-28 | Abbvie, Inc. | Low acidic species compositions and methods for producing and using the same using displacement chromatography |
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JP7019233B2 (ja) | 2013-07-11 | 2022-02-15 | モデルナティエックス インコーポレイテッド | CRISPR関連タンパク質をコードする合成ポリヌクレオチドおよび合成sgRNAを含む組成物ならびに使用方法 |
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US9085618B2 (en) | 2013-10-18 | 2015-07-21 | Abbvie, Inc. | Low acidic species compositions and methods for producing and using the same |
US9181337B2 (en) | 2013-10-18 | 2015-11-10 | Abbvie, Inc. | Modulated lysine variant species compositions and methods for producing and using the same |
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KR102265924B1 (ko) | 2014-10-31 | 2021-06-15 | 삼성바이오에피스 주식회사 | Pdk 불활성화에 의한 폴리펩타이드의 생산 |
WO2016125937A1 (ko) * | 2015-02-06 | 2016-08-11 | 경북대학교 산학협력단 | Pdk2를 이용한 여성 갱년기 질환 예방 또는 치료제의 스크리닝 방법 및 상기 방법으로 스크리닝 된 치료제를 유효성분으로 포함하는 여성 갱년기 질환의 예방 또는 치료용 약학적 조성물 |
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US11242510B2 (en) | 2016-05-02 | 2022-02-08 | The Regents Of The University Of California | Mammalian cells devoid of lactate dehydrogenase activity |
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