DK2514750T3 - Bromphenylsubstituerede thiazolyldihydropyrimidiner - Google Patents

Bromphenylsubstituerede thiazolyldihydropyrimidiner

Info

Publication number
DK2514750T3
DK2514750T3 DK12176861.8T DK12176861T DK2514750T3 DK 2514750 T3 DK2514750 T3 DK 2514750T3 DK 12176861 T DK12176861 T DK 12176861T DK 2514750 T3 DK2514750 T3 DK 2514750T3
Authority
DK
Denmark
Prior art keywords
thiazolyldihydropyrimidines
bromphenyl
substituted
substituted thiazolyldihydropyrimidines
Prior art date
Application number
DK12176861.8T
Other languages
English (en)
Other versions
DK2514750T5 (da
Inventor
Siegfried Goldmann
Jing Li
Yisong Liu
Original Assignee
Sunshine Lake Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40155886&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK2514750(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Sunshine Lake Pharma Co Ltd filed Critical Sunshine Lake Pharma Co Ltd
Application granted granted Critical
Publication of DK2514750T3 publication Critical patent/DK2514750T3/da
Publication of DK2514750T5 publication Critical patent/DK2514750T5/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
DK12176861.8T 2007-06-18 2008-06-18 Bromphenylsubstituerede thiazolyldihydropyrimidiner DK2514750T5 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN200710119019 2007-06-18
EP08757463A EP2159224B1 (en) 2007-06-18 2008-06-18 Bromo-phenyl substituted thiazolyl dihydropyrimidines

Publications (2)

Publication Number Publication Date
DK2514750T3 true DK2514750T3 (da) 2013-12-02
DK2514750T5 DK2514750T5 (da) 2014-02-17

Family

ID=40155886

Family Applications (2)

Application Number Title Priority Date Filing Date
DK12176861.8T DK2514750T5 (da) 2007-06-18 2008-06-18 Bromphenylsubstituerede thiazolyldihydropyrimidiner
DK08757463.8T DK2159224T3 (da) 2007-06-18 2008-06-18 Bromphenylsubstituerede thiazolyldihydropyrimidiner

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK08757463.8T DK2159224T3 (da) 2007-06-18 2008-06-18 Bromphenylsubstituerede thiazolyldihydropyrimidiner

Country Status (15)

Country Link
US (4) USRE45004E1 (da)
EP (2) EP2159224B1 (da)
JP (2) JP5361879B2 (da)
KR (1) KR101173892B1 (da)
CN (2) CN101328171A (da)
AU (1) AU2008265397C1 (da)
BR (1) BRPI0813237B8 (da)
CA (1) CA2691056C (da)
DK (2) DK2514750T5 (da)
ES (2) ES2442907T3 (da)
HK (1) HK1174035A1 (da)
PL (2) PL2514750T3 (da)
PT (2) PT2159224E (da)
RU (1) RU2443703C2 (da)
WO (1) WO2008154817A1 (da)

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CN103664897B (zh) * 2012-09-01 2018-04-03 广东东阳光药业有限公司 二氢嘧啶类化合物及其在药物中的应用
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CN103664899B (zh) * 2012-09-11 2017-06-16 广东东阳光药业有限公司 杂芳基取代的二氢嘧啶类化合物及其在药物中的应用
TWI561520B (en) 2012-09-27 2016-12-11 Sunshine Lake Pharma Co Ltd Crystalline forms of dihydropyrimidine derivatives
CN105188703A (zh) * 2013-03-20 2015-12-23 美国印第安纳大学研究和技术公司 荧光-hap：用于细胞中的hbv核的诊断性染色剂
AU2014352404B2 (en) 2013-11-19 2018-07-19 Sunshine Lake Pharma Co., Ltd. Dihydropyrimidine compounds and their application in pharmaceuticals
CN104672223B (zh) 2013-11-27 2018-03-13 广东东阳光药业有限公司 二氢嘧啶衍生物的制备方法及其中间体
RU2682672C2 (ru) * 2014-03-28 2019-03-20 Саншайн Лейк Фарма Ко., Лтд. Соединения дигидропиримидина и их применение в фармацевтических препаратах
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JP6668468B2 (ja) 2015-11-03 2020-03-18 エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ Ｈｂｖキャプシドアセンブリ阻害剤とインターフェロンの併用療法
JP2019526562A (ja) 2016-08-24 2019-09-19 エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ Ｈｂｖキャプシドアセンブリ阻害剤とヌクレオシ（チ）ド類似体の併用療法
PT3587420T (pt) 2017-02-23 2021-06-04 Fujian Cosunter Pharmaceutical Co Ltd Composto tricíclico e suas aplicações
CN110475775B (zh) * 2017-03-31 2023-05-09 富士胶片株式会社 4-吡啶酮化合物或其盐、包含4-吡啶酮化合物的药物组合物及剂
JP2020525490A (ja) 2017-06-27 2020-08-27 ヤンセン ファーマシューティカ エヌ．ベー． ヘテロアリールジヒドロピリミジン誘導体及びｂ型肝炎感染を治療する方法
CN107501257B (zh) * 2017-08-17 2020-05-29 山东大学 二氢嘧啶-三氮唑类衍生物及其制备方法与应用
JP7333342B2 (ja) 2018-05-25 2023-08-24 チア タイ ティエンチン ファーマシューティカル グループ カンパニー リミテッド ２，３－ジヒドロ－１ｈ－ピロリジン－７－ホルムアミド誘導体およびその使用
US11053235B2 (en) 2018-08-09 2021-07-06 Janssen Sciences Ireland Unlimited Company Substituted 1,4-dihydropyrimidines for the treatment of HBV infection or HBV-induced diseases
JP7118354B2 (ja) 2018-08-23 2022-08-16 福建▲広▼生中霖生物科技有限公司 三環式化合物の結晶形及びその使用
WO2020255016A1 (en) 2019-06-18 2020-12-24 Janssen Sciences Ireland Unlimited Company Combination of hepatitis b virus (hbv) vaccines and dihydropyrimidine derivatives as capsid assembly modulators
AU2020385518A1 (en) 2019-11-22 2022-06-09 Chia Tai Tianqing Pharmaceutical Group Co., Ltd. Crystal form of nucleoprotein inhibitor and use thereof
CN116888118A (zh) 2021-02-05 2023-10-13 和博医药有限公司 苯基二氢嘧啶类化合物及其应用
WO2022268154A1 (zh) * 2021-06-24 2022-12-29 上海齐鲁制药研究中心有限公司 新型抗乙肝化合物

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Also Published As

Publication number Publication date
DK2514750T5 (da) 2014-02-17
USRE44987E1 (en) 2014-07-01
PT2514750E (pt) 2014-01-23
JP2010530374A (ja) 2010-09-09
JP5970421B2 (ja) 2016-08-17
ES2391597T3 (es) 2012-11-28
RU2443703C2 (ru) 2012-02-27
AU2008265397A1 (en) 2008-12-24
EP2159224B1 (en) 2012-08-01
PL2159224T3 (pl) 2012-12-31
BRPI0813237B8 (pt) 2021-05-25
KR101173892B1 (ko) 2012-08-16
BRPI0813237A2 (pt) 2014-12-23
EP2159224A1 (en) 2010-03-03
JP2013231036A (ja) 2013-11-14
KR20100038104A (ko) 2010-04-12
EP2159224A4 (en) 2011-08-03
CA2691056A1 (en) 2008-12-24
BRPI0813237B1 (pt) 2020-01-07
PL2514750T3 (pl) 2014-05-30
USRE45004E1 (en) 2014-07-08
US20120282221A1 (en) 2012-11-08
US20100240655A1 (en) 2010-09-23
AU2008265397B2 (en) 2011-07-21
AU2008265397C1 (en) 2013-08-29
WO2008154817A1 (fr) 2008-12-24
AU2008265397B9 (en) 2011-08-04
CA2691056C (en) 2014-03-11
CN102066369B (zh) 2013-05-29
EP2514750B1 (en) 2013-11-20
CN102066369A (zh) 2011-05-18
DK2159224T3 (da) 2012-08-20
CN101328171A (zh) 2008-12-24
HK1174035A1 (en) 2013-05-31
US8343969B2 (en) 2013-01-01
PT2159224E (pt) 2012-10-24
JP5361879B2 (ja) 2013-12-04
ES2442907T3 (es) 2014-02-14
EP2514750A1 (en) 2012-10-24
US8236797B2 (en) 2012-08-07
RU2010101212A (ru) 2011-07-27

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