DK2262803T3 - Polysubstituerede derivater af 2-aryl-6-phenyl-imidazo(1,2-A)pyridiner, fremstilling og terapeutisk anvendelse heraf - Google Patents

Polysubstituerede derivater af 2-aryl-6-phenyl-imidazo(1,2-A)pyridiner, fremstilling og terapeutisk anvendelse heraf

Info

Publication number: DK2262803T3
Authority: DK; Denmark
Prior art keywords: pyridines; imidazo; aryl; phenyl; preparation
Prior art date: 2008-03-21

Application number

DK09754041.3T

Other languages

English (en)

Inventor

Peretti Danielle De

Yannick Evanno

Original Assignee

Sanofi Sa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2008-03-21

Filing date

2009-03-20

Publication date

2013-02-04

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39764893&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK2262803(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2009-03-20 Application filed by Sanofi Sa filed Critical Sanofi Sa

2013-02-04 Application granted granted Critical

2013-02-04 Publication of DK2262803T3 publication Critical patent/DK2262803T3/da

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders

DK09754041.3T 2008-03-21 2009-03-20 Polysubstituerede derivater af 2-aryl-6-phenyl-imidazo(1,2-A)pyridiner, fremstilling og terapeutisk anvendelse heraf DK2262803T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
FR0801580A FR2928921B1 (fr)	2008-03-21	2008-03-21	Derives polysubstitues de 2-aryl-6-phenyl-imidazo°1,2-a!pyridines, leur preparation et leur application en therapeutique
PCT/FR2009/000297 WO2009144391A1 (fr)	2008-03-21	2009-03-20	DÉRIVÉS POLYSUBSTITUES DE 2-ARYL-6-PHENYL-IMIDAZO[1,2- α]PYRIDINES, LEUR PRÉPARATION ET LEUR APPLICATION EN THÉRAPEUTIQUE

Publications (1)

Publication Number	Publication Date
DK2262803T3 true DK2262803T3 (da)	2013-02-04

Family

ID=39764893

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK09754041.3T DK2262803T3 (da)	2008-03-21	2009-03-20	Polysubstituerede derivater af 2-aryl-6-phenyl-imidazo(1,2-A)pyridiner, fremstilling og terapeutisk anvendelse heraf

Country Status (30)

Country	Link
US (1)	US8148370B2 (da)
EP (1)	EP2262803B1 (da)
JP (1)	JP5508383B2 (da)
KR (1)	KR20100129774A (da)
CN (1)	CN102036988B (da)
AR (1)	AR070992A1 (da)
AU (1)	AU2009253231B2 (da)
BR (1)	BRPI0908999A8 (da)
CA (1)	CA2718953C (da)
CL (1)	CL2009000695A1 (da)
CO (1)	CO6300865A2 (da)
CY (1)	CY1113549T1 (da)
DK (1)	DK2262803T3 (da)
EA (1)	EA018266B1 (da)
ES (1)	ES2397931T3 (da)
FR (1)	FR2928921B1 (da)
HR (1)	HRP20130029T1 (da)
IL (1)	IL208248A0 (da)
MA (1)	MA32246B1 (da)
ME (2)	ME01098B (da)
MX (1)	MX2010010259A (da)
NZ (1)	NZ588081A (da)
PE (1)	PE20091818A1 (da)
PL (1)	PL2262803T3 (da)
PT (1)	PT2262803E (da)
RS (1)	RS52652B (da)
SI (1)	SI2262803T1 (da)
TW (1)	TW201000477A (da)
UY (1)	UY31727A (da)
WO (1)	WO2009144391A1 (da)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2928922B1 (fr) *	2008-03-21	2010-04-23	Sanofi Aventis	Derives de 2-aryl-6-phenyl-imidazo°1,2-a!pyridines polysubstitues, leur preparation et leur application en therapeutique
FR2928923B1 (fr) *	2008-03-21	2010-04-23	Sanofi Aventis	Derives polysubstitues de 2-heteroaryl-6-phenyl-imidazo °1,2-a!pyridines, leur preparation et leur application en therapeutiques
FR2928924B1 (fr) *	2008-03-21	2010-04-23	Sanofi Aventis	Derives polysubstitues de 6-heteroaryle-imidazo°1,2-a! pyridines, leur preparation et leur application en therapeutique
FR2953520B1 (fr)	2009-12-04	2011-11-25	Sanofi Aventis	Derives de diphenyl-pyrazolopyridines, leur preparation et leur application en therapeutique
EP3365340B1 (en)	2015-10-19	2022-08-10	Incyte Corporation	Heterocyclic compounds as immunomodulators
MD3377488T2 (ro)	2015-11-19	2023-02-28	Incyte Corp	Compuși heterociclici ca imunomodulatori
SG11201805300QA (en)	2015-12-22	2018-07-30	Incyte Corp	Heterocyclic compounds as immunomodulators
ES2906460T3 (es)	2016-05-06	2022-04-18	Incyte Corp	Compuestos heterocíclicos como inmunomoduladores
US20170342060A1 (en)	2016-05-26	2017-11-30	Incyte Corporation	Heterocyclic compounds as immunomodulators
CA3028685A1 (en)	2016-06-20	2017-12-28	Incyte Corporation	Heterocyclic compounds as immunomodulators
US20180016260A1 (en)	2016-07-14	2018-01-18	Incyte Corporation	Heterocyclic compounds as immunomodulators
ES2941716T3 (es)	2016-08-29	2023-05-25	Incyte Corp	Compuestos heterocíclicos como inmunomoduladores
US20180179179A1 (en)	2016-12-22	2018-06-28	Incyte Corporation	Heterocyclic compounds as immunomodulators
HRP20221216T1 (hr)	2016-12-22	2022-12-23	Incyte Corporation	Derivati tetrahidro imidazo[4,5-c]piridina kao induktori internalizacije pd-l1
US20180179201A1 (en)	2016-12-22	2018-06-28	Incyte Corporation	Heterocyclic compounds as immunomodulators
ES2934230T3 (es)	2016-12-22	2023-02-20	Incyte Corp	Derivados de benzooxazol como inmunomoduladores
FI3774791T3 (fi)	2018-03-30	2023-03-21	Incyte Corp	Heterosyklisiä yhdisteitä immunomodulaattoreina
CN112752756A (zh)	2018-05-11	2021-05-04	因赛特公司	作为PD-L1免疫调节剂的四氢-咪唑并[4,5-c]吡啶衍生物
TW202115059A (zh)	2019-08-09	2021-04-16	美商英塞特公司	Ｐｄ—１／ｐｄ—ｌ１抑制劑之鹽
AU2020357514A1 (en)	2019-09-30	2022-04-07	Incyte Corporation	Pyrido[3,2-d]pyrimidine compounds as immunomodulators
WO2021096849A1 (en)	2019-11-11	2021-05-20	Incyte Corporation	Salts and crystalline forms of a pd-1/pd-l1 inhibitor
IL302590A (en)	2020-11-06	2023-07-01	Incyte Corp	Process for preparing PD-1/PD-L1 inhibitor and salts and crystalline forms thereof
US11780836B2 (en)	2020-11-06	2023-10-10	Incyte Corporation	Process of preparing a PD-1/PD-L1 inhibitor
US11760756B2 (en)	2020-11-06	2023-09-19	Incyte Corporation	Crystalline form of a PD-1/PD-L1 inhibitor

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2903106B1 (fr) *	2006-07-03	2010-07-30	Sanofi Aventis	Utilisations de 2-benzoyl-imidazopyridines en therapeutique
FR2903107B1 (fr) *	2006-07-03	2008-08-22	Sanofi Aventis Sa	Derives d'imidazopyridine-2-carboxamides, leur preparation et leur application en therapeutique
FR2903105A1 (fr) *	2006-07-03	2008-01-04	Sanofi Aventis Sa	Derives de 2-benzoyl-imidazopyridines, leur preparation et leur application en therapeutique
FR2906250B1 (fr) *	2006-09-22	2008-10-31	Sanofi Aventis Sa	Derives de 2-aryl-6phenyl-imidazo(1,2-a) pyridines, leur preparation et leur application en therapeutique
FR2928922B1 (fr) *	2008-03-21	2010-04-23	Sanofi Aventis	Derives de 2-aryl-6-phenyl-imidazo°1,2-a!pyridines polysubstitues, leur preparation et leur application en therapeutique
FR2928923B1 (fr) *	2008-03-21	2010-04-23	Sanofi Aventis	Derives polysubstitues de 2-heteroaryl-6-phenyl-imidazo °1,2-a!pyridines, leur preparation et leur application en therapeutiques

2008
- 2008-03-21 FR FR0801580A patent/FR2928921B1/fr not_active Expired - Fee Related
2009
- 2009-03-19 AR ARP090100985A patent/AR070992A1/es not_active Application Discontinuation
- 2009-03-19 PE PE2009000415A patent/PE20091818A1/es not_active Application Discontinuation
- 2009-03-20 TW TW098109237A patent/TW201000477A/zh unknown
- 2009-03-20 ES ES09754041T patent/ES2397931T3/es active Active
- 2009-03-20 BR BRPI0908999A patent/BRPI0908999A8/pt not_active IP Right Cessation
- 2009-03-20 MX MX2010010259A patent/MX2010010259A/es active IP Right Grant
- 2009-03-20 UY UY0001031727A patent/UY31727A/es not_active Application Discontinuation
- 2009-03-20 NZ NZ588081A patent/NZ588081A/en not_active IP Right Cessation
- 2009-03-20 EP EP09754041A patent/EP2262803B1/fr active Active
- 2009-03-20 PL PL09754041T patent/PL2262803T3/pl unknown
- 2009-03-20 CN CN2009801185642A patent/CN102036988B/zh not_active Expired - Fee Related
- 2009-03-20 ME MEP-2010-151A patent/ME01098B/me unknown
- 2009-03-20 JP JP2011500258A patent/JP5508383B2/ja not_active Expired - Fee Related
- 2009-03-20 PT PT97540413T patent/PT2262803E/pt unknown
- 2009-03-20 KR KR1020107023410A patent/KR20100129774A/ko not_active Application Discontinuation
- 2009-03-20 CL CL2009000695A patent/CL2009000695A1/es unknown
- 2009-03-20 DK DK09754041.3T patent/DK2262803T3/da active
- 2009-03-20 AU AU2009253231A patent/AU2009253231B2/en not_active Ceased
- 2009-03-20 SI SI200930480T patent/SI2262803T1/sl unknown
- 2009-03-20 ME MEP-2013-4A patent/ME01469B/me unknown
- 2009-03-20 RS RS20130008A patent/RS52652B/en unknown
- 2009-03-20 CA CA2718953A patent/CA2718953C/fr not_active Expired - Fee Related
- 2009-03-20 EA EA201071110A patent/EA018266B1/ru not_active IP Right Cessation
- 2009-03-20 WO PCT/FR2009/000297 patent/WO2009144391A1/fr active Application Filing
2010
- 2010-09-14 US US12/881,805 patent/US8148370B2/en not_active Expired - Fee Related
- 2010-09-19 IL IL208248A patent/IL208248A0/en unknown
- 2010-09-21 CO CO10116606A patent/CO6300865A2/es not_active Application Discontinuation
- 2010-10-19 MA MA33272A patent/MA32246B1/fr unknown
2013
- 2013-01-15 HR HRP20130029AT patent/HRP20130029T1/hr unknown
- 2013-01-17 CY CY20131100052T patent/CY1113549T1/el unknown

Also Published As

Publication number	Publication date
EP2262803A1 (fr)	2010-12-22
FR2928921B1 (fr)	2010-04-23
PL2262803T3 (pl)	2013-03-29
PE20091818A1 (es)	2009-12-12
HRP20130029T1 (hr)	2013-02-28
EP2262803B1 (fr)	2012-10-17
SI2262803T1 (sl)	2013-02-28
AU2009253231B2 (en)	2013-07-11
RS52652B (en)	2013-06-28
EA201071110A1 (ru)	2011-04-29
KR20100129774A (ko)	2010-12-09
US20110065699A1 (en)	2011-03-17
NZ588081A (en)	2012-07-27
WO2009144391A1 (fr)	2009-12-03
CN102036988B (zh)	2013-08-07
BRPI0908999A8 (pt)	2016-07-12
MA32246B1 (fr)	2011-04-01
TW201000477A (en)	2010-01-01
CL2009000695A1 (es)	2010-08-13
EA018266B1 (ru)	2013-06-28
UY31727A (es)	2009-11-10
AU2009253231A1 (en)	2009-12-03
ES2397931T3 (es)	2013-03-12
ME01469B (me)	2014-04-20
PT2262803E (pt)	2013-01-28
US8148370B2 (en)	2012-04-03
ME01098B (me)	2012-12-20
AR070992A1 (es)	2010-05-19
CY1113549T1 (el)	2016-06-22
MX2010010259A (es)	2011-06-01
IL208248A0 (en)	2010-12-30
CA2718953C (fr)	2016-08-16
CA2718953A1 (fr)	2009-12-03
BRPI0908999A2 (pt)	2015-08-04
JP5508383B2 (ja)	2014-05-28
CO6300865A2 (es)	2011-07-21
FR2928921A1 (fr)	2009-09-25
JP2011515380A (ja)	2011-05-19
CN102036988A (zh)	2011-04-27

Publication	Publication Date	Title
DK2262803T3 (da)	2013-02-04	Polysubstituerede derivater af 2-aryl-6-phenyl-imidazo(1,2-A)pyridiner, fremstilling og terapeutisk anvendelse heraf
DK2069342T3 (da)	2010-08-23	Derivater af 2-aryl-6-phenyl-imidazol[1,2-A]pyridiner, fremstilling og terapeutisk anvendelse deraf
DK2049525T3 (da)	2010-05-03	N-laminoheteroaryl)-1H-indol-2-carboxamid-derivater, og fremstilling og terapeutisk anvendelse deraf
FR2928922B1 (fr)	2010-04-23	Derives de 2-aryl-6-phenyl-imidazo°1,2-a!pyridines polysubstitues, leur preparation et leur application en therapeutique
DK2133332T3 (da)	2013-09-30	(aza)indolderivat og anvendelse deraf til medicinske formål
FR2928924B1 (fr)	2010-04-23	Derives polysubstitues de 6-heteroaryle-imidazo°1,2-a! pyridines, leur preparation et leur application en therapeutique
ZA201006726B (en)	2011-11-30	Polysubstituted derivatives of 2-heteroaryl-6-phenyl-imidazo[1,2-a] pyridines,and preparation and therapeutic use thereof
DK3461503T3 (da)	2022-02-14	Fremgangsmåder til indgivelse af tetrahydrobiopterin, associerede sammensætninger og målingsfremgangsmåder
DK2170890T3 (da)	2012-02-27	Cytotoksiske midler, der omfatter nye tomaymycin-derivater, og terapeutisk anvendelse deraf
IL204663A0 (en)	2010-11-30	Nicotinamide derivatives, preparastion thereof and therapeutic use thereof
DK2158201T3 (da)	2011-08-01	Derivater af 7-alkynyl-1,8-naphthyridon, fremgangsmåde til fremstilling deraf og anvendelse deraf i terapi
DK2007769T3 (da)	2011-10-03	Dimerer af artemisininderivater, fremstilling deraf og terapeutisk anvendelse deraf
DK2448940T3 (da)	2014-08-25	Derivater af 6,7,8,9 tetrahydro-pyrimido{1,2-a}pyrimidin-4-on, fremstilling og farmaceutisk anvendelse heraf
DK2262778T3 (da)	2019-11-18	1-benzyl-3-hydroxymethylindazolderivativer og brug deraf i behandling af sygdomme baseret på ekspression af mcp-1, cxcr1 og p40
DK2158194T3 (da)	2011-09-12	Derivater af 7-alkynyl-1,8-naphtyridoner, fremgangsmåde til fremstilling deraf og terapeutisk anvendelse deraf
DK2382215T3 (da)	2014-10-27	Derivater af 2-pyridin-2-yl-pyrazol-3(2h)-on, fremstilling og terapeutisk anvendelse heraf
DK1773829T3 (da)	2009-04-20	Aminotropanderivater, fremstilling og terapeutiske anvendelser heraf
DK2188253T3 (da)	2012-07-02	Indol-2-onderivater, der er disubstitueret i 3-stillingen, fremstilling deraf og terapeutisk anvendelse deraf
ATE540023T1 (de)	2012-01-15	Neuartige 3-aminoalkyl-1,3-dihydro-2h-indol-2-on- derivate, ihre herstellung und therapeutische verwendung
DK2185561T3 (da)	2011-10-10	Derivater af 1,2,3,4-tetrahydropyrrolo(1,2-a)pyrazin-6-carboxamid og 2,3,4,5-tetrahydroprrolo(1,2-a)-diazepin-7-carboxamid, fremstilling deraf og terapeutisk anvendelse deraf
DK1940840T3 (da)	2010-11-22	6-heteroarylpyridoindolon-derivater, fremstilling deraf og terapeutisk anvendelse deraf
DK2310383T3 (da)	2012-03-26	2-oxo-alkyl-1-piperazin-2-onderivater, fremstilling deraf og terapeutisk anvendelse deraf
FR2925901B1 (fr)	2011-03-04	DERIVES DE N-HETEROCYCLIQUE-IMIDAZO°1,2-a!PYRIDINE-2- CARBOXAMIDES, LEUR PREPARATION ET LEUR APPLICATION EN THERAPEUTIQUE
DK2234966T3 (da)	2014-01-06	Azetidinderivater, fremstilling og terapeutisk anvendelse heraf
DK2106401T3 (da)	2012-07-02	Derivater af pyrrolopyridin-2-carboxamider, fremstilling deraf og terapeutisk anvendelse deraf