DK159786D0 - Fremgangsmaade til fremstilling af en krystallinsk form af natriumsalatet af et oximderivat af 7-aminothiazolylacetamidocephalosporansyre - Google Patents

Fremgangsmaade til fremstilling af en krystallinsk form af natriumsalatet af et oximderivat af 7-aminothiazolylacetamidocephalosporansyre

Info

Publication number: DK159786D0
Authority: DK; Denmark
Prior art keywords: salad; sodium; preparing; oxime derivative; aminothiazolylacetamidocephalosporanic
Prior art date: 1977-08-17

Application number

DK159786A

Other languages

English (en)

Other versions

DK163514C (da

DK163514B (da

DK159786A (da

Inventor

Gaston Amiard

Dieter Bormann

Walter Duerchheimer

Jean Jolly

Original Assignee

Roussel Uclaf

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1977-08-17

Filing date

1986-04-09

Publication date

1986-04-09

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9194564&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK159786(D0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1986-04-09 Application filed by Roussel Uclaf filed Critical Roussel Uclaf

1986-04-09 Publication of DK159786D0 publication Critical patent/DK159786D0/da

1986-04-09 Publication of DK159786A publication Critical patent/DK159786A/da

1992-03-09 Publication of DK163514B publication Critical patent/DK163514B/da

1992-07-27 Application granted granted Critical

1992-07-27 Publication of DK163514C publication Critical patent/DK163514C/da

Links

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
- A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
- C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
- C07D501/26—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group
- C07D501/34—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group with the 7-amino radical acylated by carboxylic acids containing hetero rings

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Oncology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Communicable Diseases (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Cephalosporin Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

DK159786A 1977-08-17 1986-04-09 Fremgangsmaade til fremstilling af en krystallinsk form af natriumsaltet af et oximderivat af 7-aminothiazolylacetamidocephalosporansyre DK163514C (da)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
FR7725142		1977-08-17
FR7725142A FR2400519A1 (fr)	1977-08-17	1977-08-17	Forme cristalline du sel de sodium d'un derive oximine de l'acide 7-amino-thiazolyl acetamido cephalosporanique, son procede de preparation et son application comme medicament
DK361078A DK152213C (da)	1977-08-17	1978-08-16	Fremgangsmaade til fremstilling af en krystallinsk form af natriumsaltet af et oximderivat af 7-aminothiazolylacetamidocephalosporansyre
DK361078		1978-08-16

Publications (4)

Publication Number	Publication Date
DK159786D0 true DK159786D0 (da)	1986-04-09
DK159786A DK159786A (da)	1986-04-09
DK163514B DK163514B (da)	1992-03-09
DK163514C DK163514C (da)	1992-07-27

Family

ID=9194564

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
DK361078A DK152213C (da)	1977-08-17	1978-08-16	Fremgangsmaade til fremstilling af en krystallinsk form af natriumsaltet af et oximderivat af 7-aminothiazolylacetamidocephalosporansyre
DK159786A DK163514C (da)	1977-08-17	1986-04-09	Fremgangsmaade til fremstilling af en krystallinsk form af natriumsaltet af et oximderivat af 7-aminothiazolylacetamidocephalosporansyre

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
DK361078A DK152213C (da)	1977-08-17	1978-08-16	Fremgangsmaade til fremstilling af en krystallinsk form af natriumsaltet af et oximderivat af 7-aminothiazolylacetamidocephalosporansyre

Country Status (34)

Country	Link
US (1)	US4224371A (da)
EP (1)	EP0001024B1 (da)
JP (1)	JPS5441890A (da)
AT (2)	AT366049B (da)
AU (1)	AU520898B2 (da)
BG (2)	BG33888A3 (da)
CA (1)	CA1121343A (da)
CS (2)	CS207646B2 (da)
DD (1)	DD137588A5 (da)
DE (1)	DE2860358D1 (da)
DK (2)	DK152213C (da)
EG (1)	EG13520A (da)
ES (1)	ES472381A1 (da)
FI (1)	FI65433C (da)
FR (1)	FR2400519A1 (da)
GE (2)	GEP19960475B (da)
GR (1)	GR73661B (da)
HR (1)	HRP931395B1 (da)
HU (1)	HU181497B (da)
IE (1)	IE47230B1 (da)
IL (1)	IL55186A (da)
IT (1)	IT1107961B (da)
MD (2)	MD225C2 (da)
MX (2)	MX155976A (da)
NO (1)	NO156168C (da)
NZ (1)	NZ188163A (da)
OA (1)	OA06016A (da)
PL (1)	PL126619B1 (da)
PT (1)	PT68431A (da)
RO (1)	RO79999A (da)
SI (1)	SI7811917A8 (da)
SU (2)	SU799666A3 (da)
YU (1)	YU42166B (da)
ZA (1)	ZA784187B (da)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS60120886A (ja) *	1983-12-02	1985-06-28	Takeda Chem Ind Ltd	セフェムカルボン酸のナトリウム塩の結晶
DE3485860T2 (de) *	1983-12-29	1993-01-14	Mochida Pharm Co Ltd	Cephalosporinverbindungen, verfahren zu ihrer herstellung und pharmazeutishe praeparate.
JPS60142987A (ja) *	1983-12-29	1985-07-29	Mochida Pharmaceut Co Ltd	セフアロスポリン誘導体
US4840945A (en) *	1985-04-01	1989-06-20	Mochida Pharmaceutical Co., Ltd.	Cephalosporin derivatives
ATE138664T1 (de) *	1985-08-12	1996-06-15	Upjohn Co	Umwandlung des cephalosporin-hydrohalid-salzes zu einem alkalimetallsalz
US4880798A (en) *	1986-11-25	1989-11-14	Mochida Pharmaceutical Co., Ltd.	Cephalosporin derivatives
JPS63132893A (ja) *	1986-11-25	1988-06-04	Mochida Pharmaceut Co Ltd	新規セフアロスポリン誘導体、その製法およびそれらを有効成分とする抗菌剤
RU2021274C1 (ru)	1991-05-17	1994-10-15	Польска Акадэмия Наук Институт Хэмии Органичнэй	Способ получения аминотиазолильных производных цефалоспорина
US5318781A (en) *	1993-04-06	1994-06-07	Hoffmann-La Roche Inc.	Absorption enhancement of antibiotics
US5574154A (en) *	1994-09-29	1996-11-12	Alnejma Bulk Pharmaceutical Co. A.B.P.C.	Process for the preparation of cephalosporanic compounds
GB9423459D0 (en) *	1994-11-21	1995-01-11	Biochemie Gmbh	Silylation process
AT402928B (de) *	1994-12-23	1997-09-25	Biochemie Gmbh	Neues verfahren zur herstellung von cefotaxim
AU690482B2 (en) *	1996-03-18	1998-04-23	Ranbaxy Laboratories Limited	Process for producing cephalosporin antibiotics
GB9717629D0 (en) *	1997-08-21	1997-10-22	Johnson Matthey Plc	Removal of residual organic solvents
WO2001092254A1 (fr) *	2000-05-30	2001-12-06	Fujisawa Pharmaceutical Co., Ltd.	Procede permettant de remplacer des solvants contenus dans des cristaux de type clathrates
WO2004063203A1 (en) *	2003-01-10	2004-07-29	Orchid Chemicals & Pharmaceuticals Ltd	Process for the preparation of cefotaxime sodium
CN100361995C (zh) *	2004-10-27	2008-01-16	山东瑞阳制药有限公司	注射级无菌头孢噻肟钠的一步法制备工艺

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3970651A (en) *	1974-01-07	1976-07-20	Bristol-Myers Company	Crystalline cephalosporin derivative
US3985747A (en) *	1974-05-24	1976-10-12	Bristol-Myers Company	Crystalline sesquihydrate of 7-[D-α-amino-α-(p-hydroxyphenyl)acetamido]-3-(1,2,3-triazol-5-ylthiomethyl)-3-cephem-4-carboxylic acid
DK154939C (da) *	1974-12-19	1989-06-12	Takeda Chemical Industries Ltd	Analogifremgangsmaade til fremstilling af thiazolylacetamido-cephemforbindelser eller farmaceutisk acceptable salte eller estere deraf
US4006138A (en) *	1975-04-11	1977-02-01	Eli Lilly And Company	Crystalline form of sodium O-formylcefamandole
DE2760123C2 (de) *	1976-01-23	1986-04-30	Roussel-Uclaf, Paris	7-Aminothiazolyl-syn-oxyiminoacetamidocephalosporansäuren, ihre Herstellung und sie enthaltende pharmazeutische Zusammensetzungen
SE440655B (sv) *	1976-01-23	1985-08-12	Roussel Uclaf	Sett att framstella nya oximderivat av 7-amino-tiazolyl-acetamido-cefalosporansyra

1977
- 1977-08-17 FR FR7725142A patent/FR2400519A1/fr active Granted
1978
- 1978-07-20 IL IL55186A patent/IL55186A/xx active IP Right Grant
- 1978-07-22 OA OA56566A patent/OA06016A/xx unknown
- 1978-07-24 ZA ZA00784187A patent/ZA784187B/xx unknown
- 1978-08-02 DD DD78207090A patent/DD137588A5/xx unknown
- 1978-08-03 AT AT0563578A patent/AT366049B/de not_active IP Right Cessation
- 1978-08-03 DE DE7878400072T patent/DE2860358D1/de not_active Expired
- 1978-08-03 EP EP78400072A patent/EP0001024B1/fr not_active Expired
- 1978-08-04 ES ES472381A patent/ES472381A1/es not_active Expired
- 1978-08-08 IT IT50648/78A patent/IT1107961B/it active Protection Beyond IP Right Term
- 1978-08-08 CS CS785183A patent/CS207646B2/cs unknown
- 1978-08-09 SU SU782645701A patent/SU799666A3/ru active
- 1978-08-10 YU YU1917/78A patent/YU42166B/xx unknown
- 1978-08-10 US US05/932,437 patent/US4224371A/en not_active Expired - Lifetime
- 1978-08-10 SI SI7811917A patent/SI7811917A8/sl unknown
- 1978-08-11 GR GR56985A patent/GR73661B/el unknown
- 1978-08-11 MX MX7926A patent/MX155976A/es unknown
- 1978-08-11 MX MX787309U patent/MX5448E/es unknown
- 1978-08-15 BG BG7942035A patent/BG33888A3/xx unknown
- 1978-08-15 BG BG7840671A patent/BG33887A3/xx unknown
- 1978-08-16 EG EG510/78A patent/EG13520A/xx active
- 1978-08-16 NO NO782782A patent/NO156168C/no unknown
- 1978-08-16 RO RO78101982A patent/RO79999A/ro unknown
- 1978-08-16 HU HU78RO993A patent/HU181497B/hu unknown
- 1978-08-16 FI FI782494A patent/FI65433C/fi not_active IP Right Cessation
- 1978-08-16 DK DK361078A patent/DK152213C/da not_active IP Right Cessation
- 1978-08-16 PT PT68431A patent/PT68431A/pt unknown
- 1978-08-16 NZ NZ188163A patent/NZ188163A/xx unknown
- 1978-08-16 PL PL1978209080A patent/PL126619B1/pl unknown
- 1978-08-16 AU AU38965/78A patent/AU520898B2/en not_active Expired
- 1978-08-16 CA CA000309454A patent/CA1121343A/fr not_active Expired
- 1978-08-17 IE IE1669/78A patent/IE47230B1/en not_active IP Right Cessation
- 1978-08-17 JP JP9958078A patent/JPS5441890A/ja active Granted
1979
- 1979-06-27 CS CS794439A patent/CS207647B2/cs unknown
1980
- 1980-01-31 AT AT0052280A patent/AT366050B/de not_active IP Right Cessation
- 1980-03-12 SU SU802891755A patent/SU852175A3/ru active
1986
- 1986-04-09 DK DK159786A patent/DK163514C/da not_active IP Right Cessation
1993
- 1993-07-31 GE GEAP19931371A patent/GEP19960475B/en unknown
- 1993-07-31 GE GEAP19931355A patent/GEP19960476B/en unknown
- 1993-11-11 HR HRP-1917/78A patent/HRP931395B1/xx not_active IP Right Cessation
1994
- 1994-09-08 MD MD94-0267A patent/MD225C2/ro unknown
- 1994-09-08 MD MD94-0275A patent/MD247C2/ro unknown

Also Published As

Publication number	Publication date
JPS6145626B2 (da)	1986-10-08
BG33888A3 (en)	1983-05-16
NO156168C (no)	1987-08-19
FR2400519A1 (fr)	1979-03-16
MX5448E (es)	1983-08-09
DE2860358D1 (en)	1981-03-12
FI65433C (fi)	1984-05-10
ES472381A1 (es)	1979-03-16
EP0001024A1 (fr)	1979-03-07
DD137588A5 (de)	1979-09-12
GEP19960475B (en)	1996-07-22
DK163514C (da)	1992-07-27
JPS5441890A (en)	1979-04-03
OA06016A (fr)	1981-06-30
NO156168B (no)	1987-04-27
IL55186A0 (en)	1978-09-29
YU42166B (en)	1988-06-30
AT366049B (de)	1982-03-10
IE47230B1 (en)	1984-01-25
IL55186A (en)	1981-07-31
NZ188163A (en)	1981-10-19
ATA563578A (de)	1981-07-15
SI7811917A8 (en)	1997-12-31
ATA52280A (de)	1981-07-15
BG33887A3 (en)	1983-05-16
PT68431A (fr)	1978-09-01
MD247B1 (ro)	1995-07-31
SU852175A3 (ru)	1981-07-30
AU3896578A (en)	1980-02-21
YU191778A (en)	1983-02-28
GEP19960476B (en)	1996-07-22
DK361078A (da)	1979-02-18
MD225C2 (ro)	1995-12-31
AT366050B (de)	1982-03-10
DK163514B (da)	1992-03-09
EP0001024B1 (fr)	1981-01-21
IT1107961B (it)	1985-12-02
EG13520A (en)	1982-03-31
ZA784187B (en)	1979-09-26
FI782494A (fi)	1979-02-18
DK152213C (da)	1988-07-11
IE781669L (en)	1979-02-17
GR73661B (da)	1984-03-28
DK159786A (da)	1986-04-09
CS207646B2 (en)	1981-08-31
CS207647B2 (en)	1981-08-31
RO79999A (ro)	1982-10-11
CA1121343A (fr)	1982-04-06
HRP931395B1 (en)	1996-04-30
FI65433B (fi)	1984-01-31
MD225B1 (ro)	1995-06-30
MX155976A (es)	1988-06-06
US4224371A (en)	1980-09-23
AU520898B2 (en)	1982-03-04
PL209080A1 (pl)	1979-06-04
PL126619B1 (en)	1983-08-31
SU799666A3 (ru)	1981-01-23
FR2400519B1 (da)	1980-05-16
IT7850648A0 (it)	1978-08-08
HU181497B (en)	1983-07-28
DK152213B (da)	1988-02-08
MD247C2 (ro)	1995-12-31
NO782782L (no)	1979-02-20

Legal Events

Date	Code	Title	Description
1998-09-28	PUP	Patent expired
2000-05-29	PUP	Patent expired

Publication	Publication Date	Title
DK63479A (da)	1979-08-16	Fremgangsmaade til fremstilling af derivater af dehydrocycliske iminosyrer
DK159786D0 (da)	1986-04-09	Fremgangsmaade til fremstilling af en krystallinsk form af natriumsalatet af et oximderivat af 7-aminothiazolylacetamidocephalosporansyre
DK129578A (da)	1978-09-26	Fremgangsmaade til fremstilling af oximderivater af 3-acetoxymethyl-7-aminothiazolylacetamidocephalosporansyre
DK196077A (da)	1978-09-16	Fremgangsmaade til fremstilling af di-n-propyleddikesyre
DK502078A (da)	1979-05-15	Frefmgangsmaade til fremstilling af cephalosporansyrederivater
DK262578A (da)	1978-12-21	Fremgangsmaade til fremstilling af dihydropyridinderivater
DK153978A (da)	1978-10-08	Fremgangsmaade til fremstilling af oxalsyreestere
DK129678A (da)	1978-09-26	Fremgangsmaade til fremstilling af oximderivater af 7-aminothiazolylacetamidocephalosporansyre
DK99980A (da)	1980-09-09	Fremgangsmaade til fremstilling af mercaptoacyldihydropyrazolcarboxylsyrederivater
DK7278A (da)	1978-07-08	Fremgangsmaade til fremstilling af substituerede oximer
DK276378A (da)	1978-12-22	Fremgangsmaade til fremstilling af nye derivater af amidinopenicillansyre
DK524878A (da)	1979-05-26	Fremgangsmaade til fremstilling af et hidtil ukendt pyridinderivat
DK215576A (da)	1976-11-17	Fremgangsmade til fremstilling af et flavonderivat
DK102978A (da)	1978-09-15	Fremgangsmaade til fremstilling af et fast steroidpraeparat
DK68978A (da)	1978-08-19	Fremgangsmaade til fremstilling af oximderivater af 3-thiadiazolythiomethyl-7-aminothiazolylacetamidocephalosporansyre
DK85178A (da)	1978-08-25	Fremgangsmaade til fremstilling af 9-(i-hydroxyethoxymethyl)-guanin-derivater
DK154554C (da)	1989-04-17	Fremgangsmaade til fremstilling af alfa-methyl-carbazol-2-eddikesyrederivater
DK553378A (da)	1979-06-09	Fremgangsmaade til fremstilling af 1-hydrocarbylpyrrol-2-eddikesyrederivater
DK145063C (da)	1983-01-17	Fremgangsmaade til fremstilling af et antibioticum kaldet forbindelse 46192
DK159784C (da)	1991-04-22	Fremgangsmaade til fremstilling af 3-brommethyl-3-cephem-sulfoxidderivater
DK144703C (da)	1982-10-11	Analogifremgangsmaade til fremstilling af ikke-glycosidiske theophyllin-sukker-derivater
DK158038C (da)	1990-08-13	Fremgangsmaade til fremstilling af di-n-propylacetonitril
DK457680A (da)	1981-05-01	Fremgangsmaade til fremstilling af et urinstofderivat
DK89280A (da)	1980-09-03	Fremgangsmaade til fremstilling af et carbazolderivat
DK148886C (da)	1986-05-12	Fremgangsmaade til fremstilling af diacetone-2-ketogulonsyre