DK1589019T3 - Stereoselektiv fremgangsmåde til fremstilling af clopidogrel - Google Patents

Stereoselektiv fremgangsmåde til fremstilling af clopidogrel

Info

Publication number
DK1589019T3
DK1589019T3 DK04009280T DK04009280T DK1589019T3 DK 1589019 T3 DK1589019 T3 DK 1589019T3 DK 04009280 T DK04009280 T DK 04009280T DK 04009280 T DK04009280 T DK 04009280T DK 1589019 T3 DK1589019 T3 DK 1589019T3
Authority
DK
Denmark
Prior art keywords
diastereomers
halo
mixture
formulae
substituted
Prior art date
Application number
DK04009280T
Other languages
English (en)
Inventor
Jiri Stohandl
Jaroslav Frantisek
Winfried Ness
Original Assignee
Ratiopharm Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ratiopharm Gmbh filed Critical Ratiopharm Gmbh
Application granted granted Critical
Publication of DK1589019T3 publication Critical patent/DK1589019T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C213/10—Separation; Purification; Stabilisation; Use of additives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
    • C07D333/20—Radicals substituted by singly bound hetero atoms other than halogen by nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Catalysts (AREA)
  • Semiconductor Lasers (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Hydrogenated Pyridines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Saccharide Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
DK04009280T 2004-04-20 2004-04-20 Stereoselektiv fremgangsmåde til fremstilling af clopidogrel DK1589019T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP04009280A EP1589019B1 (de) 2004-04-20 2004-04-20 Stereoselektives Verfahren zur Herstellung von Clopidogrel

Publications (1)

Publication Number Publication Date
DK1589019T3 true DK1589019T3 (da) 2008-11-17

Family

ID=34924660

Family Applications (2)

Application Number Title Priority Date Filing Date
DK04009280T DK1589019T3 (da) 2004-04-20 2004-04-20 Stereoselektiv fremgangsmåde til fremstilling af clopidogrel
DK04803495T DK1737868T3 (da) 2004-04-20 2004-12-03 Stereoselektiv fremgangsmåde til fremstilling af clopidogrel

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK04803495T DK1737868T3 (da) 2004-04-20 2004-12-03 Stereoselektiv fremgangsmåde til fremstilling af clopidogrel

Country Status (20)

Country Link
US (2) US7507827B2 (da)
EP (2) EP1589019B1 (da)
JP (1) JP2007533671A (da)
CN (1) CN100522970C (da)
AT (2) ATE404566T1 (da)
AU (1) AU2004319901A1 (da)
BR (1) BRPI0418760A (da)
CA (1) CA2563662A1 (da)
CY (2) CY1107908T1 (da)
DE (2) DE502004007831D1 (da)
DK (2) DK1589019T3 (da)
ES (2) ES2309416T3 (da)
HR (1) HRP20080091T3 (da)
NO (1) NO20065313L (da)
PL (2) PL1589019T3 (da)
PT (2) PT1589019E (da)
RU (1) RU2369610C2 (da)
SI (2) SI1589019T1 (da)
UA (1) UA93030C2 (da)
WO (1) WO2005113559A1 (da)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2909377A1 (fr) * 2006-12-05 2008-06-06 Arkema France Procede de synthese d'esters (meth)acryliques catalyse par un titanate de polyol

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1196334B (it) * 1984-11-22 1988-11-16 Alfa Chem Ital Processo per la risoluzione ottica di miscugli racemi di acidi alfanaftil-propionici
DE4428531A1 (de) * 1994-08-12 1996-02-15 Boehringer Ingelheim Kg Neue enantiomerenreine Pyridylcycloalkylethylamine und deren Salze sowie Verfahren zu ihrer Herstellung
HU225503B1 (en) * 1997-05-13 2007-01-29 Sanofi Aventis Novel 2-(2-halophenyl)-2-(2-(2-thienyl)-ethylamino)-acetamides and process for producing them
FR2769313B1 (fr) * 1997-10-06 2000-04-21 Sanofi Sa Derives d'esters hydroxyacetiques, leur procede de preparation et leur utilisation comme intermediaires de synthese
US20030045727A1 (en) * 2000-02-08 2003-03-06 Seiji Nakano Process for preparing optically active secondary alcohols having nitrogenous or oxygenic functional groups
GB0125708D0 (en) * 2001-10-26 2001-12-19 Generics Uk Ltd Novel compounds and processes

Also Published As

Publication number Publication date
ATE387454T1 (de) 2008-03-15
CA2563662A1 (en) 2005-12-01
SI1589019T1 (sl) 2008-12-31
UA93030C2 (ru) 2011-01-10
US7799952B2 (en) 2010-09-21
WO2005113559A1 (de) 2005-12-01
PL1589019T3 (pl) 2008-12-31
PT1737868E (pt) 2008-03-13
SI1737868T1 (sl) 2008-06-30
HRP20080091T3 (en) 2008-03-31
CY1108391T1 (el) 2014-02-12
EP1737868B1 (de) 2008-02-27
NO20065313L (no) 2006-11-20
RU2006137112A (ru) 2008-05-27
DK1737868T3 (da) 2008-06-02
PL1737868T3 (pl) 2008-06-30
RU2369610C2 (ru) 2009-10-10
PT1589019E (pt) 2008-10-08
DE502004006368D1 (de) 2008-04-10
CN100522970C (zh) 2009-08-05
US20090149677A1 (en) 2009-06-11
CY1107908T1 (el) 2013-09-04
AU2004319901A1 (en) 2005-12-01
ATE404566T1 (de) 2008-08-15
CN1972950A (zh) 2007-05-30
EP1737868A1 (de) 2007-01-03
ES2300854T3 (es) 2008-06-16
BRPI0418760A (pt) 2007-10-09
DE502004007831D1 (de) 2008-09-25
EP1589019B1 (de) 2008-08-13
US20070219166A1 (en) 2007-09-20
US7507827B2 (en) 2009-03-24
JP2007533671A (ja) 2007-11-22
ES2309416T3 (es) 2008-12-16
EP1589019A1 (de) 2005-10-26

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