PT1589019E - Processo estereosselectivo para a preparação de clopidogrel - Google Patents

Processo estereosselectivo para a preparação de clopidogrel Download PDF

Info

Publication number
PT1589019E
PT1589019E PT04009280T PT04009280T PT1589019E PT 1589019 E PT1589019 E PT 1589019E PT 04009280 T PT04009280 T PT 04009280T PT 04009280 T PT04009280 T PT 04009280T PT 1589019 E PT1589019 E PT 1589019E
Authority
PT
Portugal
Prior art keywords
diastereomers
halo
mixture
formulae
substituted
Prior art date
Application number
PT04009280T
Other languages
English (en)
Inventor
Jaroslav Frantisek
Jiri Stohandl
Winfried Ness
Original Assignee
Ratiopharm Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ratiopharm Gmbh filed Critical Ratiopharm Gmbh
Publication of PT1589019E publication Critical patent/PT1589019E/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C213/10—Separation; Purification; Stabilisation; Use of additives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
    • C07D333/20—Radicals substituted by singly bound hetero atoms other than halogen by nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Catalysts (AREA)
  • Semiconductor Lasers (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Hydrogenated Pyridines (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
PT04009280T 2004-04-20 2004-04-20 Processo estereosselectivo para a preparação de clopidogrel PT1589019E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP04009280A EP1589019B1 (de) 2004-04-20 2004-04-20 Stereoselektives Verfahren zur Herstellung von Clopidogrel

Publications (1)

Publication Number Publication Date
PT1589019E true PT1589019E (pt) 2008-10-08

Family

ID=34924660

Family Applications (2)

Application Number Title Priority Date Filing Date
PT04009280T PT1589019E (pt) 2004-04-20 2004-04-20 Processo estereosselectivo para a preparação de clopidogrel
PT04803495T PT1737868E (pt) 2004-04-20 2004-12-03 Processo estereoselectivo para a preparação de clopidogrel

Family Applications After (1)

Application Number Title Priority Date Filing Date
PT04803495T PT1737868E (pt) 2004-04-20 2004-12-03 Processo estereoselectivo para a preparação de clopidogrel

Country Status (20)

Country Link
US (2) US7507827B2 (pt)
EP (2) EP1589019B1 (pt)
JP (1) JP2007533671A (pt)
CN (1) CN100522970C (pt)
AT (2) ATE404566T1 (pt)
AU (1) AU2004319901A1 (pt)
BR (1) BRPI0418760A (pt)
CA (1) CA2563662A1 (pt)
CY (2) CY1107908T1 (pt)
DE (2) DE502004007831D1 (pt)
DK (2) DK1589019T3 (pt)
ES (2) ES2309416T3 (pt)
HR (1) HRP20080091T3 (pt)
NO (1) NO20065313L (pt)
PL (2) PL1589019T3 (pt)
PT (2) PT1589019E (pt)
RU (1) RU2369610C2 (pt)
SI (2) SI1589019T1 (pt)
UA (1) UA93030C2 (pt)
WO (1) WO2005113559A1 (pt)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2909377A1 (fr) 2006-12-05 2008-06-06 Arkema France Procede de synthese d'esters (meth)acryliques catalyse par un titanate de polyol

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1196334B (it) * 1984-11-22 1988-11-16 Alfa Chem Ital Processo per la risoluzione ottica di miscugli racemi di acidi alfanaftil-propionici
DE4428531A1 (de) * 1994-08-12 1996-02-15 Boehringer Ingelheim Kg Neue enantiomerenreine Pyridylcycloalkylethylamine und deren Salze sowie Verfahren zu ihrer Herstellung
HU225503B1 (en) * 1997-05-13 2007-01-29 Sanofi Aventis Novel 2-(2-halophenyl)-2-(2-(2-thienyl)-ethylamino)-acetamides and process for producing them
FR2769313B1 (fr) * 1997-10-06 2000-04-21 Sanofi Sa Derives d'esters hydroxyacetiques, leur procede de preparation et leur utilisation comme intermediaires de synthese
WO2001058843A1 (fr) * 2000-02-08 2001-08-16 Asahi Kasei Kabushiki Kaisha Procede de preparation d'alcools secondaires optiquement actifs possedant des groupes fonctionnels azote ou oxygene
GB0125708D0 (en) * 2001-10-26 2001-12-19 Generics Uk Ltd Novel compounds and processes

Also Published As

Publication number Publication date
DK1589019T3 (da) 2008-11-17
RU2006137112A (ru) 2008-05-27
NO20065313L (no) 2006-11-20
US20070219166A1 (en) 2007-09-20
WO2005113559A1 (de) 2005-12-01
DE502004006368D1 (de) 2008-04-10
ATE404566T1 (de) 2008-08-15
RU2369610C2 (ru) 2009-10-10
AU2004319901A1 (en) 2005-12-01
CN1972950A (zh) 2007-05-30
DE502004007831D1 (de) 2008-09-25
CY1107908T1 (el) 2013-09-04
CY1108391T1 (el) 2014-02-12
CA2563662A1 (en) 2005-12-01
EP1737868B1 (de) 2008-02-27
ES2300854T3 (es) 2008-06-16
US7507827B2 (en) 2009-03-24
BRPI0418760A (pt) 2007-10-09
HRP20080091T3 (en) 2008-03-31
US20090149677A1 (en) 2009-06-11
ES2309416T3 (es) 2008-12-16
ATE387454T1 (de) 2008-03-15
SI1737868T1 (sl) 2008-06-30
PL1589019T3 (pl) 2008-12-31
SI1589019T1 (sl) 2008-12-31
EP1737868A1 (de) 2007-01-03
PT1737868E (pt) 2008-03-13
JP2007533671A (ja) 2007-11-22
EP1589019A1 (de) 2005-10-26
PL1737868T3 (pl) 2008-06-30
DK1737868T3 (da) 2008-06-02
CN100522970C (zh) 2009-08-05
EP1589019B1 (de) 2008-08-13
UA93030C2 (ru) 2011-01-10
US7799952B2 (en) 2010-09-21

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