DK157550C - Analogifremgangsmaade til fremstilling af 8-aminoalkyl-xantinderivater. - Google Patents

Analogifremgangsmaade til fremstilling af 8-aminoalkyl-xantinderivater.

Info

Publication number
DK157550C
DK157550C DK342883A DK342883A DK157550C DK 157550 C DK157550 C DK 157550C DK 342883 A DK342883 A DK 342883A DK 342883 A DK342883 A DK 342883A DK 157550 C DK157550 C DK 157550C
Authority
DK
Denmark
Prior art keywords
image
alkyl
hydrogen
aminoalkyl
preparation
Prior art date
Application number
DK342883A
Other languages
Danish (da)
English (en)
Other versions
DK342883D0 (da
DK342883A (da
DK157550B (da
Inventor
Gilbert Regnier
Claude Guillonneau
Jacques Duhault
Michelle Boulanger
Original Assignee
Adir
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Adir filed Critical Adir
Publication of DK342883D0 publication Critical patent/DK342883D0/da
Publication of DK342883A publication Critical patent/DK342883A/da
Publication of DK157550B publication Critical patent/DK157550B/da
Application granted granted Critical
Publication of DK157550C publication Critical patent/DK157550C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/52—Two oxygen atoms
    • C07D239/54—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
    • C07D239/545—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals with other hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
    • C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
    • C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
    • C07D473/08—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3 with methyl radicals in positions 1 and 3, e.g. theophylline
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
    • C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
    • C07D473/10—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3 with methyl radicals in positions 3 and 7, e.g. theobromine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
    • C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
    • C07D473/12—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3 with methyl radicals in positions 1, 3, and 7, e.g. caffeine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK342883A 1982-07-28 1983-07-27 Analogifremgangsmaade til fremstilling af 8-aminoalkyl-xantinderivater. DK157550C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8213155 1982-07-28
FR8213155A FR2531085A1 (fr) 1982-07-28 1982-07-28 Nouveaux derives de la xanthine, leur procede de preparation et les compositions pharmaceutiques les renfermant

Publications (4)

Publication Number Publication Date
DK342883D0 DK342883D0 (da) 1983-07-27
DK342883A DK342883A (da) 1984-01-29
DK157550B DK157550B (da) 1990-01-22
DK157550C true DK157550C (da) 1990-06-11

Family

ID=9276395

Family Applications (1)

Application Number Title Priority Date Filing Date
DK342883A DK157550C (da) 1982-07-28 1983-07-27 Analogifremgangsmaade til fremstilling af 8-aminoalkyl-xantinderivater.

Country Status (24)

Country Link
US (1) US4548820A (ko)
EP (1) EP0103497B1 (ko)
JP (1) JPS5942383A (ko)
KR (1) KR870001268B1 (ko)
AT (1) ATE17728T1 (ko)
AU (1) AU560809B2 (ko)
CA (1) CA1207766A (ko)
DD (1) DD216934A5 (ko)
DE (1) DE3362022D1 (ko)
DK (1) DK157550C (ko)
ES (1) ES8500275A1 (ko)
FR (1) FR2531085A1 (ko)
GR (1) GR78891B (ko)
HU (1) HU188353B (ko)
IE (1) IE55773B1 (ko)
IL (1) IL69362A (ko)
MA (1) MA19860A1 (ko)
NO (1) NO159091C (ko)
NZ (1) NZ205035A (ko)
OA (1) OA07508A (ko)
PH (1) PH19275A (ko)
PT (1) PT77110B (ko)
SU (2) SU1240361A3 (ko)
ZA (1) ZA835496B (ko)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH648559A5 (de) * 1981-07-20 1985-03-29 Siegfried Ag Theophyllinderivate und verfahren zu deren herstellung.
FR2558162B1 (fr) * 1984-01-17 1986-04-25 Adir Nouveaux derives de la xanthine, leurs procedes de preparation et les compositions pharmaceutiques les renfermant
HU197746B (en) * 1985-09-05 1989-05-29 Sandoz Ag Process for producing xantin derivatives and pharmaceutical compositions containing them
US4810706A (en) * 1985-12-20 1989-03-07 Recherche Syntex Piperazine derivatives of theophylline and theobromine
GB8716313D0 (en) * 1987-07-10 1987-08-19 Janssen Pharmaceutica Nv 2-(heterocyclylalkyl)imidazopyridines
US5298508A (en) * 1988-07-19 1994-03-29 The United States Of America As Represented By The Department Of Health And Human Services Irreversible inhibitors of adenosine receptors
US5290782A (en) * 1989-09-01 1994-03-01 Kyowa Hakko Kogyo Co., Ltd. Xanthine derivatives
FR2659656B1 (fr) * 1990-03-15 1994-09-09 Sanofi Sa Derives de pyrimidinedione-2,4 et medicaments les contenant.
DE4019892A1 (de) * 1990-06-22 1992-01-02 Boehringer Ingelheim Kg Neue xanthinderivate
US5484920A (en) * 1992-04-08 1996-01-16 Kyowa Hakko Kogyo Co., Ltd. Therapeutic agent for Parkinson's disease
JP2613355B2 (ja) * 1992-09-28 1997-05-28 協和醗酵工業株式会社 パーキンソン氏病治療剤
WO1994025462A1 (en) * 1993-05-03 1994-11-10 The United States Of America, Represented By The 8-substituted 1,3,7-trialkyl-xanthine derivatives as a2-selective adenosine receptor antagonists
US5661153A (en) * 1994-07-19 1997-08-26 Japan Energy Corporation 1-arylpyrimidine derivatives and pharmaceutical use thereof
DE19702785A1 (de) * 1997-01-27 1998-07-30 Bayer Ag Neue cyclische Harnstoffderivate
EA006685B1 (ru) 1999-08-21 2006-02-24 Алтана Фарма Аг Синергетическая композиция
KR20050115331A (ko) 2003-04-01 2005-12-07 어플라이드 리서치 시스템스 에이알에스 홀딩 엔.브이. 불임증 포스포디에스터라제의 억제제
CA2522971A1 (en) 2003-04-25 2004-11-11 Novacardia, Inc. Method of improved diuresis in individuals with impaired renal function
KR20070008689A (ko) * 2004-04-16 2007-01-17 노바카르디아, 인코포레이션 아데노신 ａ１ 수용체 길항제 및 알도스테론 억제제를포함하는 병용 요법
EP1805180A1 (en) * 2004-10-22 2007-07-11 SmithKline Beecham Corporation Xanthine derivatives with hm74a receptor activity
WO2007137417A1 (en) * 2006-05-26 2007-12-06 Neuromed Pharmaceuticals Ltd. Heterocyclic compounds as calcium channel blockers
JP2008025761A (ja) * 2006-07-24 2008-02-07 Kanaflex Corporation 排水管更生用樹脂管
PT2159226T (pt) * 2007-03-29 2016-12-16 Joint-Stock Company Obninsk Chemical Pharmaceutical Company Agente anti-histamínico e antialérgico e um método para a produção do mesmo
RU2333212C3 (ru) * 2007-03-29 2019-08-26 Общество С Ограниченной Ответственностью "Фармвинг" ПРОИЗВОДНЫЕ 1-И 7-[ω-(БЕНЗГИДРИЛ-4-ПИПЕРАЗИНИЛ-1)АЛКИЛ]-3-АЛКИЛКСАНТИНОВ, ОБЛАДАЮЩИЕ ПРОТИВОГИСТАМИННОЙ И АНТИАЛЛЕРГИЧЕСКОЙ АКТИВНОСТЬЮ

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH409974A (de) * 1959-03-25 1966-03-31 Merckle Kg Chem Pharm L Verfahren zur Herstellung neuer therapeutisch wirksamer Coffeino-(8)-alkylendiamine
GB1133989A (en) * 1964-12-08 1968-11-20 Chugai Pharmaceutical Co Ltd Theophylline derivatives, their salts and process for preparing the same
FR7828M (ko) * 1967-11-13 1970-05-25
JPS55118488A (en) * 1979-03-05 1980-09-11 Eisai Co Ltd Theobromine derivative and its preparation
JPS5618983A (en) * 1979-07-25 1981-02-23 Eisai Co Ltd Theophylline derivative and its preapration
US4426383A (en) * 1980-09-04 1984-01-17 Eisai Co., Ltd. Theophylline and theobromine derivatives
DE3046927A1 (de) * 1980-12-11 1982-07-15 Josef Dipl.-Chem.Dr.rer.nat. 1000 Berlin Klosa 8-dialkylaminoalkylaether-coffein-platin-komplexe , verfahren zu ihrer herstellung und sie enthaltende arzneimittel
ES506046A0 (es) * 1981-10-06 1983-02-01 Invest Tecnica Aplicada Procedimiento de obtencion de nuevas xantinas con actividad farmacologica

Also Published As

Publication number Publication date
ES524532A0 (es) 1984-10-01
SU1240361A3 (ru) 1986-06-23
CA1207766A (fr) 1986-07-15
GR78891B (ko) 1984-10-02
DK342883D0 (da) 1983-07-27
KR870001268B1 (ko) 1987-06-30
DK342883A (da) 1984-01-29
JPS5942383A (ja) 1984-03-08
NO832742L (no) 1984-01-30
US4548820A (en) 1985-10-22
JPH0359903B2 (ko) 1991-09-12
ZA835496B (en) 1984-03-28
IE55773B1 (en) 1991-01-16
IE831762L (en) 1984-01-28
NO159091C (no) 1988-11-30
AU560809B2 (en) 1987-04-16
PT77110A (fr) 1983-08-01
PH19275A (en) 1986-02-21
DD216934A5 (de) 1985-01-02
EP0103497A1 (fr) 1984-03-21
ATE17728T1 (de) 1986-02-15
KR840005445A (ko) 1984-11-12
NO159091B (no) 1988-08-22
HU188353B (en) 1986-04-28
DE3362022D1 (en) 1986-03-13
NZ205035A (en) 1986-04-11
OA07508A (fr) 1985-03-31
IL69362A (en) 1986-07-31
DK157550B (da) 1990-01-22
IL69362A0 (en) 1983-11-30
AU1736183A (en) 1984-02-02
FR2531085B1 (ko) 1984-11-23
ES8500275A1 (es) 1984-10-01
EP0103497B1 (fr) 1986-01-29
SU1245261A3 (ru) 1986-07-15
FR2531085A1 (fr) 1984-02-03
PT77110B (fr) 1986-01-27
MA19860A1 (fr) 1984-04-01

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