DK1539734T3 - Quinolylpropylpiperidinderivater og deres anvendelse som antimikrobielle midler - Google Patents

Quinolylpropylpiperidinderivater og deres anvendelse som antimikrobielle midler

Info

Publication number
DK1539734T3
DK1539734T3 DK03769606T DK03769606T DK1539734T3 DK 1539734 T3 DK1539734 T3 DK 1539734T3 DK 03769606 T DK03769606 T DK 03769606T DK 03769606 T DK03769606 T DK 03769606T DK 1539734 T3 DK1539734 T3 DK 1539734T3
Authority
DK
Denmark
Prior art keywords
alkyl
cooh
alkoxy
substituted
cyc
Prior art date
Application number
DK03769606T
Other languages
Danish (da)
English (en)
Inventor
Eric Bacque
Antony Bigot
Ahmad Youssef El
Jean-Luc Malleron
Serge Mignani
Baptiste Ronan
Michel Tabart
Fabrice Viviani
Original Assignee
Novexel
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novexel filed Critical Novexel
Application granted granted Critical
Publication of DK1539734T3 publication Critical patent/DK1539734T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
DK03769606T 2002-09-11 2003-09-10 Quinolylpropylpiperidinderivater og deres anvendelse som antimikrobielle midler DK1539734T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0211213A FR2844268B1 (fr) 2002-09-11 2002-09-11 Derives de la quinolyl propyl piperidine, leurs procedes et intermediaires de preparation et les compositions qui les contiennent

Publications (1)

Publication Number Publication Date
DK1539734T3 true DK1539734T3 (da) 2006-06-06

Family

ID=31725984

Family Applications (1)

Application Number Title Priority Date Filing Date
DK03769606T DK1539734T3 (da) 2002-09-11 2003-09-10 Quinolylpropylpiperidinderivater og deres anvendelse som antimikrobielle midler

Country Status (22)

Country Link
US (1) US6841562B2 (de)
EP (1) EP1539734B1 (de)
JP (1) JP2006500403A (de)
KR (1) KR20050042196A (de)
CN (1) CN100415736C (de)
AT (1) ATE319705T1 (de)
AU (1) AU2003278297A1 (de)
BR (1) BR0314185A (de)
CA (1) CA2498628A1 (de)
DE (1) DE60303954T2 (de)
DK (1) DK1539734T3 (de)
EA (1) EA009769B1 (de)
ES (1) ES2256783T3 (de)
FR (1) FR2844268B1 (de)
MA (1) MA27433A1 (de)
MX (1) MXPA05002655A (de)
NO (1) NO20051754L (de)
OA (1) OA12922A (de)
PT (1) PT1539734E (de)
RS (1) RS20050212A (de)
TN (1) TNSN05069A1 (de)
WO (1) WO2004024713A1 (de)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0112834D0 (en) 2001-05-25 2001-07-18 Smithkline Beecham Plc Medicaments
JP4508650B2 (ja) * 2002-01-29 2010-07-21 グラクソ グループ リミテッド アミノピペリジン化合物、当該化合物の製法および当該化合物を含有する医薬組成物
AR038240A1 (es) * 2002-01-29 2005-01-05 Glaxo Group Ltd Compuesto de piperidina, uso del mismo para la fabricacion de un medicamento, composicion farmaceutica que lo comprende y procedimiento para su preparacion
AR040336A1 (es) 2002-06-26 2005-03-30 Glaxo Group Ltd Compuesto de piperidina, uso del mismo para la fabricacion de un medicamento, composicion farmaceutica que lo comprende y procedimiento para preparar dicho compuesto
TW200406413A (en) * 2002-06-26 2004-05-01 Glaxo Group Ltd Compounds
JP4704755B2 (ja) 2002-11-05 2011-06-22 グラクソスミスクライン・リミテッド・ライアビリティ・カンパニー 抗菌剤
ATE479683T1 (de) 2002-11-05 2010-09-15 Glaxo Group Ltd Antibakterielle mittel
AR042486A1 (es) * 2002-12-18 2005-06-22 Glaxo Group Ltd Compuesto de quinolina y naftiridina halosustituido en la posicion 3, procedimiento para preparar el compuesto, composicion farmaceutica que lo comprende y su uso para preparar dicha composicion .
GB2413863A (en) * 2004-05-08 2005-11-09 Ibm Method and system for distribution of information
EP1773831A1 (de) * 2004-07-08 2007-04-18 Glaxo Group Limited Antibakterielle mittel
ES2343127T3 (es) * 2004-10-05 2010-07-23 Actelion Pharmaceuticals Ltd. Nuevos antibioticos de piperidina.
EP1846416A4 (de) * 2005-01-25 2009-07-01 Glaxo Group Ltd Antibakterielle wirkstoffe
WO2006081264A1 (en) 2005-01-25 2006-08-03 Glaxo Group Limited Antibacterial agents
EP1846418A4 (de) * 2005-01-25 2009-12-23 Glaxo Group Ltd Antibakterielle wirkstoffe
US7709472B2 (en) * 2005-01-25 2010-05-04 Glaxo Group Limited Antibacterial agents
EP1846411A4 (de) * 2005-01-25 2010-08-04 Glaxo Group Ltd Antibakterielle wirkstoffe
MY150958A (en) * 2005-06-16 2014-03-31 Astrazeneca Ab Compounds for the treatment of multi-drug resistant bacterial infections
WO2007115947A1 (en) 2006-04-06 2007-10-18 Glaxo Group Limited Pyrrolo-quinoxalinone derivatives as antibacterials
EP1992628A1 (de) 2007-05-18 2008-11-19 Glaxo Group Limited Derivate und Analoge von N-Ethylquinolonen und N-Ethylazaquinolonen
US20100144717A1 (en) * 2006-12-15 2010-06-10 Janelle Comita-Prevoir 2-quinolinone and 2-quinoxalinone-derivatives and their use as antibacterial agents
AU2008240764C1 (en) * 2007-04-20 2011-10-20 Glaxo Group Limited Tricyclic nitrogen containing compounds as antibacterial agents
EP2080761A1 (de) 2008-01-18 2009-07-22 Glaxo Group Limited Verbindungen
FR2936798B1 (fr) * 2008-10-03 2012-09-28 Novexel Nouveaux composes heterocycliques azotes, leur preparation et leur utilisation comme medicaments antibacteriens.
FR2937034B1 (fr) * 2008-10-10 2012-11-23 Novexel Nouveaux composes heterocycliques azotes, leur preparation et leur utilisation comme medicaments antibacteriens
FR2936951B1 (fr) * 2008-10-10 2010-12-03 Novexel Nouvelles combinaisons de composes heterocycliques azotes antibacteriens avec d'autres composes antibacteriens et leur utilisation comme medicaments
US20110275661A1 (en) 2008-10-17 2011-11-10 Glaxo Group Limited Tricyclic nitrogen compounds used as antibacterials
US8318940B2 (en) 2009-01-15 2012-11-27 Glaxo Group Limited Naphthyridin-2 (1 H)-one compounds useful as antibacterials
MX2017002321A (es) 2014-08-22 2017-08-02 Glaxosmithkline Ip Dev Ltd Compuestos que contienen nitrogeno triciclico para tratar infeccion por neisseria gonorrhoeae.
UY36851A (es) 2015-08-16 2017-03-31 Glaxosmithkline Ip Dev Ltd Compuestos para uso en aplicaciones antibacterianas
KR102231872B1 (ko) * 2019-10-04 2021-03-26 성균관대학교산학협력단 포스포늄일리드를 이용한 디아진-n-옥사이드의 위치선택적 알킬화 방법

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL89028A0 (en) * 1988-01-29 1989-08-15 Lilly Co Eli Quinoline,quinazoline and cinnoline derivatives
US6117884A (en) * 1997-07-31 2000-09-12 Daeuble; John 4-substituted quinoline derivatives having fungicidal activity
EP1144404A1 (de) * 1999-01-20 2001-10-17 Smithkline Beecham Plc Piperidinylchinoline als proteintyrosinkinasehemmer
FR2798656B1 (fr) * 1999-09-17 2004-12-17 Aventis Pharma Sa Derives de la quinolyl propyl piperidine, leur preparation et les compositions qui les contiennent
FR2816618B1 (fr) * 2000-11-15 2002-12-27 Aventis Pharma Sa Derives heterocyclylalcoyl piperidine, leur preparation et les compositions qui les contiennent
US6603005B2 (en) * 2000-11-15 2003-08-05 Aventis Pharma S.A. Heterocyclylalkylpiperidine derivatives, their preparation and compositions containing them
FR2822154B1 (fr) * 2001-03-13 2005-10-21 Aventis Pharma Sa Derives de la quinolyl propyl piperidine, leur preparation et les compositions qui les contiennent

Also Published As

Publication number Publication date
KR20050042196A (ko) 2005-05-04
EA009769B1 (ru) 2008-04-28
ES2256783T3 (es) 2006-07-16
DE60303954D1 (de) 2006-05-04
CN100415736C (zh) 2008-09-03
RS20050212A (en) 2007-09-21
US6841562B2 (en) 2005-01-11
BR0314185A (pt) 2005-08-09
ATE319705T1 (de) 2006-03-15
PT1539734E (pt) 2006-05-31
CA2498628A1 (fr) 2004-03-25
FR2844268B1 (fr) 2004-10-22
EP1539734B1 (de) 2006-03-08
EP1539734A1 (de) 2005-06-15
MA27433A1 (fr) 2005-07-01
OA12922A (fr) 2006-10-13
DE60303954T2 (de) 2006-12-07
NO20051754D0 (no) 2005-04-08
FR2844268A1 (fr) 2004-03-12
EA200500474A1 (ru) 2005-08-25
CN1681801A (zh) 2005-10-12
TNSN05069A1 (fr) 2007-05-14
JP2006500403A (ja) 2006-01-05
MXPA05002655A (es) 2005-09-08
WO2004024713A1 (fr) 2004-03-25
US20040082610A1 (en) 2004-04-29
AU2003278297A1 (en) 2004-04-30
NO20051754L (no) 2005-04-08

Similar Documents

Publication Publication Date Title
DK1539734T3 (da) Quinolylpropylpiperidinderivater og deres anvendelse som antimikrobielle midler
ECSP055644A (es) Derivados de la quinolil-propil-piperidina y su utilización
NO20101069L (no) Anvendelse av visse NMDA-affinitetsantagonister som antidepressiva
AR049739A1 (es) Derivados de aril-piridina
EA200400305A1 (ru) 2,4,5-тризамещенные производные тиазолила и их противовоспалительная активность
NO20070555L (no) Kinazolinonderivater som parp-inhibitorer
PE20060243A1 (es) Derivados de 4-amino insustituido-5-(4-urea-fenil)-pirrolotriazina
TW200510431A (en) Quinazoline derivatives
NO20092770L (no) Nye aminopyrimidinderivater som PLK1-inhibitorer
HK1073659A1 (en) Arylsulphonamide derivatives and use thereof as b1 bradykinin receptor antagonists
DK1490342T3 (da) Disubstituerede pyrazolylcarboxanilider
NO20070526L (no) Kinazolindionderivater som parp-inhibitorer
NO331165B1 (no) Derivater av dioksan-2-alkylkarbamater, fremgangsmate for fremstilling derav og anvendelse av de samme for fremstilling av medikamenter
NO20065902L (no) 3-{4-(pyridin-3-yl)fenyl}-5-(1H-,1,2,3-triazol-1-ylmetyl)-1,3-oksazolidin-2-oner som antibakterielle midler
NO20060314L (no) Nicotinamid-derivater anvendbare som PDE4-inhibitorer
NO20065873L (no) 3-(4-(2-dihydroisoksazol-3-ylpyridin-5-yl)fenyl)-5-triazol-1-ylmetyloksoazolidin-2-on derivater som MAO inhibitorer i behandlingen av bakterielle infeksjoner
NO20061832L (no) Karboksamidderivat av amidtype
ATE277042T1 (de) Antimikrobielle 4-oxochinolizine mit 2- pyridongerüsten als teilstruktur
DK0835659T3 (da) Anvendelse af ikke-peptidiske antagonister for bradykinin til fremstilling af lægemidler til behandling og forebyggelse af Alzheimer's sygdom
DE60107056D1 (de) Benzoxazolderivate als tnf und pde iv inhibitoren
BRPI0409374A (pt) composto, composição farmacêutica, uso de pelo menos um composto, e, método para o tratamento de um distúrbio médico
MY145908A (en) Amide derivatives bearing a cyclopropylaminocarbonyl substituent useful as cytokine inhibitors
NO20076037L (no) Nye tiazolidinoner uten basisk nitrogen, deres fremstilling og anvendelse som farmasoytiske midler
NO983439L (no) 1-(pyrazol-3-yl-etyl)-4-(indol-3-yl)-piperidin anvendt som medisin som virker på sentralnervesystemet
TW200503733A (en) T-shaped channel blockers