DK1485348T3 - Carbonylamino-derivater som nye inhibitorer af histandeacetylase - Google Patents
Carbonylamino-derivater som nye inhibitorer af histandeacetylaseInfo
- Publication number
- DK1485348T3 DK1485348T3 DK03708215T DK03708215T DK1485348T3 DK 1485348 T3 DK1485348 T3 DK 1485348T3 DK 03708215 T DK03708215 T DK 03708215T DK 03708215 T DK03708215 T DK 03708215T DK 1485348 T3 DK1485348 T3 DK 1485348T3
- Authority
- DK
- Denmark
- Prior art keywords
- histane
- deacetylase
- novel inhibitors
- carbonylamino derivatives
- carbonylamino
- Prior art date
Links
- 125000006297 carbonyl amino group Chemical group [H]N([*:2])C([*:1])=O 0.000 title 1
- 239000003112 inhibitor Substances 0.000 title 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
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- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
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- A61K31/402—1-aryl substituted, e.g. piretanide
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MXPA04002397A (es) | 2001-09-14 | 2004-12-02 | Methylgene Inc | Inhibidores de histona deacetilasa. |
US7868204B2 (en) | 2001-09-14 | 2011-01-11 | Methylgene Inc. | Inhibitors of histone deacetylase |
US6897220B2 (en) | 2001-09-14 | 2005-05-24 | Methylgene, Inc. | Inhibitors of histone deacetylase |
BR0307606A (pt) | 2002-03-13 | 2004-12-21 | Janssen Pharmaceutica Nv | Derivados de piperazinila, piperidinila e morfolinila como inibidores de histona desacetilase |
EA007272B1 (ru) * | 2002-03-13 | 2006-08-25 | Янссен Фармацевтика Н. В. | Новые ингибиторы гистондеацетилазы |
MXPA04007776A (es) | 2002-03-13 | 2004-10-15 | Janssen Pharmaceutica Nv | Derivados de sulfonilamino como nuevos inhibidores de histona deacetilasa. |
ATE398105T1 (de) * | 2002-03-13 | 2008-07-15 | Janssen Pharmaceutica Nv | Carbonylamino- derivativate als neue inhibitoren von histone deacetylase |
TWI319387B (en) | 2002-04-05 | 2010-01-11 | Astrazeneca Ab | Benzamide derivatives |
US8163764B2 (en) * | 2002-04-26 | 2012-04-24 | Asan Laboratories Company (Cayman) Limited | Skincare methods |
AU2003303042A1 (en) * | 2002-12-17 | 2004-07-09 | Pfizer Inc. | 2-pyridyl and 2-pyrimidyl cycloalkylene amide compounds as nr2b receptor antagonists |
KR101153335B1 (ko) | 2003-09-24 | 2012-07-05 | 메틸진 인코포레이티드 | 히스톤 데아세틸라제의 억제제 |
US7253204B2 (en) | 2004-03-26 | 2007-08-07 | Methylgene Inc. | Inhibitors of histone deacetylase |
CN1964962A (zh) | 2004-06-14 | 2007-05-16 | 霍夫曼-拉罗奇有限公司 | 噻吩异羟肟酸衍生物以及它们作为hdac抑制剂的应用 |
WO2005121134A1 (en) | 2004-06-14 | 2005-12-22 | F. Hoffmann-La Roche Ag | Thiophene derivatives, their manufacture and use as pharmaceutical agents |
CA2566512A1 (en) | 2004-06-14 | 2005-12-22 | F. Hoffmann-La Roche Ag | Hydroxamates, their manufacture and use as pharmaceutical agents |
SI1781639T1 (sl) * | 2004-07-28 | 2012-06-29 | Janssen Pharmaceutica Nv | Substituirani indolil alkil amino derivati kot novi inhibitorji histon deacetilaze |
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- 2003-03-11 ES ES03708215T patent/ES2306858T3/es not_active Expired - Lifetime
- 2003-03-11 US US10/507,788 patent/US7446109B2/en active Active
- 2003-03-11 PL PL370982A patent/PL205531B1/pl unknown
- 2003-03-11 DK DK03708215T patent/DK1485348T3/da active
- 2003-03-11 CN CNB038058847A patent/CN100503599C/zh not_active Expired - Lifetime
- 2003-03-11 EA EA200401200A patent/EA007908B1/ru not_active IP Right Cessation
- 2003-03-11 EP EP03708215A patent/EP1485348B1/en not_active Expired - Lifetime
- 2003-03-11 CA CA2476067A patent/CA2476067C/en not_active Expired - Lifetime
- 2003-03-11 DE DE60321548T patent/DE60321548D1/de not_active Expired - Lifetime
- 2003-03-12 AR ARP030100852A patent/AR039564A1/es not_active Application Discontinuation
- 2003-03-12 TW TW092105281A patent/TW200404794A/zh unknown
-
2004
- 2004-09-03 HR HR20040805A patent/HRP20040805A2/hr not_active Application Discontinuation
- 2004-09-30 NO NO20044146A patent/NO20044146L/no not_active Application Discontinuation
-
2008
- 2008-09-19 US US12/233,977 patent/US8071615B2/en not_active Expired - Fee Related
-
2011
- 2011-10-24 US US13/280,207 patent/US8394831B2/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
KR20040090981A (ko) | 2004-10-27 |
PL370982A1 (en) | 2005-06-13 |
NO20044146L (no) | 2004-09-30 |
US7446109B2 (en) | 2008-11-04 |
CA2476067C (en) | 2011-09-20 |
US8394831B2 (en) | 2013-03-12 |
BR0307607A (pt) | 2004-12-21 |
ATE398105T1 (de) | 2008-07-15 |
EA200401200A1 (ru) | 2005-02-24 |
OA12789A (en) | 2006-07-10 |
ES2306858T3 (es) | 2008-11-16 |
PL205531B1 (pl) | 2010-04-30 |
AU2003212336B2 (en) | 2008-12-18 |
US8071615B2 (en) | 2011-12-06 |
US20050148613A1 (en) | 2005-07-07 |
TW200404794A (en) | 2004-04-01 |
US20090042920A1 (en) | 2009-02-12 |
CN1642907A (zh) | 2005-07-20 |
AR039564A1 (es) | 2005-02-23 |
JP4648628B2 (ja) | 2011-03-09 |
AU2003212336A1 (en) | 2003-09-22 |
JP2005519950A (ja) | 2005-07-07 |
CA2476067A1 (en) | 2003-09-18 |
MXPA04008796A (es) | 2004-11-26 |
EP1485348A1 (en) | 2004-12-15 |
NZ534831A (en) | 2007-01-26 |
HRP20040805A2 (en) | 2005-04-30 |
DE60321548D1 (de) | 2008-07-24 |
EA007908B1 (ru) | 2007-02-27 |
WO2003076395A1 (en) | 2003-09-18 |
EP1485348B1 (en) | 2008-06-11 |
CN100503599C (zh) | 2009-06-24 |
US20120041001A1 (en) | 2012-02-16 |
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