DK1485365T3 - Sulfonyl-derivater som nye inhibitorer af histandeacetylase - Google Patents

Sulfonyl-derivater som nye inhibitorer af histandeacetylase

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Publication number
DK1485365T3
DK1485365T3 DK03711982T DK03711982T DK1485365T3 DK 1485365 T3 DK1485365 T3 DK 1485365T3 DK 03711982 T DK03711982 T DK 03711982T DK 03711982 T DK03711982 T DK 03711982T DK 1485365 T3 DK1485365 T3 DK 1485365T3
Authority
DK
Denmark
Prior art keywords
histane
deacetylase
novel inhibitors
sulfonyl derivatives
sulfonyl
Prior art date
Application number
DK03711982T
Other languages
English (en)
Inventor
Alexey Borisovich John Dyatkin
Janine Arts
Leo Jacobus Jozef Backx
Winter Hans Louis Jos De
Brandt Sven Franciscus Ann Van
Marc Gustaaf Celine Verdonck
Isabelle Noelle Constance Pilatte
Emelen Kristof Van
Lieven Meerpoel
Virginie Sophie Poncelet
Heusden Jimmy Arnold Vivia Van
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Application granted granted Critical
Publication of DK1485365T3 publication Critical patent/DK1485365T3/da

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    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
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    • A61K31/402—1-aryl substituted, e.g. piretanide
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