DK148019C - Analogifremgangsmaade til fremstilling af 2-pyridylaminobenzoesyrer eller farmaceutisk acceptable salte deraf - Google Patents

Analogifremgangsmaade til fremstilling af 2-pyridylaminobenzoesyrer eller farmaceutisk acceptable salte deraf

Info

Publication number
DK148019C
DK148019C DK351978A DK351978A DK148019C DK 148019 C DK148019 C DK 148019C DK 351978 A DK351978 A DK 351978A DK 351978 A DK351978 A DK 351978A DK 148019 C DK148019 C DK 148019C
Authority
DK
Denmark
Prior art keywords
pyridylaminobenoic
analogue
acids
preparation
acceptable salts
Prior art date
Application number
DK351978A
Other languages
English (en)
Other versions
DK148019B (da
DK351978A (da
Inventor
Kurt Schromm
Anton Mentrup
Ernst-Otto Renth
Fuegner Armin
Volker Jacobi
Original Assignee
Boehringer Sohn Ingelheim
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Sohn Ingelheim filed Critical Boehringer Sohn Ingelheim
Publication of DK351978A publication Critical patent/DK351978A/da
Publication of DK148019B publication Critical patent/DK148019B/da
Application granted granted Critical
Publication of DK148019C publication Critical patent/DK148019C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/08—Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/75—Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79—Acids; Esters
    • C07D213/80—Acids; Esters in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32—One oxygen, sulfur or nitrogen atom
    • C07D239/42—One nitrogen atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Medicinal Preparation (AREA)
DK351978A 1977-08-10 1978-08-09 Analogifremgangsmaade til fremstilling af 2-pyridylaminobenzoesyrer eller farmaceutisk acceptable salte deraf DK148019C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19772735919 DE2735919A1 (de) 1977-08-10 1977-08-10 Neue 2-pyridyl- und 2-pyrimidylaminobenzoesaeuren
DE2735919 1977-08-10

Publications (3)

Publication Number Publication Date
DK351978A DK351978A (da) 1979-02-11
DK148019B DK148019B (da) 1985-02-04
DK148019C true DK148019C (da) 1985-07-01

Family

ID=6016013

Family Applications (1)

Application Number Title Priority Date Filing Date
DK351978A DK148019C (da) 1977-08-10 1978-08-09 Analogifremgangsmaade til fremstilling af 2-pyridylaminobenzoesyrer eller farmaceutisk acceptable salte deraf

Country Status (32)

Country Link
US (1) US4241068A (da)
JP (1) JPS5430177A (da)
AT (1) AT370415B (da)
AU (1) AU520240B2 (da)
BE (1) BE869640A (da)
BG (1) BG30472A1 (da)
CA (1) CA1111037A (da)
CH (1) CH649289A5 (da)
CS (1) CS202506B2 (da)
DD (1) DD140351A5 (da)
DE (1) DE2735919A1 (da)
DK (1) DK148019C (da)
ES (5) ES472143A1 (da)
FI (1) FI71555C (da)
FR (1) FR2400017A1 (da)
GB (1) GB2002764B (da)
GR (1) GR65024B (da)
HU (1) HU179933B (da)
IE (1) IE47228B1 (da)
IT (1) IT1107960B (da)
LU (1) LU80094A1 (da)
MX (1) MX5672E (da)
NL (1) NL7808319A (da)
NO (1) NO152605C (da)
NZ (1) NZ188101A (da)
PH (1) PH19117A (da)
PL (2) PL115889B1 (da)
PT (1) PT68407A (da)
SE (1) SE444170B (da)
SU (2) SU735168A3 (da)
YU (1) YU40832B (da)
ZA (1) ZA784501B (da)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3100516A1 (de) * 1981-01-10 1982-08-12 C.H. Boehringer Sohn, 6507 Ingelheim Pyridylaminobenzoesaeuren, ihre herstellung und verwendung
FR2533567A1 (fr) * 1982-09-23 1984-03-30 Ki I Farmakologii 2-(orthocarboxyphenylamino)-6h-pyrimido (2,1-b)-quinazolone-6 et ses derives, leur procede de preparation et leur application therapeutique
US4610991A (en) * 1983-04-18 1986-09-09 Sterling Drug Inc. Antihypertensive pyridylaminobenzamide compounds
JPS60100559A (ja) * 1983-11-05 1985-06-04 Morishita Seiyaku Kk ２−アニリノ−１，６−ジヒドロ−６−オキソ−５−ピリミジンカルボン酸誘導体，その製法及び該化合物を含有する抗アレルギ−剤
US4584379A (en) * 1985-01-22 1986-04-22 Merrell Dow Pharmaceuticals Inc. Isoquinoline thromboxane synthetase inhibitors
EP0219308B1 (en) * 1985-10-16 1991-10-23 Merck Frosst Canada Inc. 2-substituted quinolines
GB9615950D0 (en) * 1996-07-30 1996-09-11 Univ Warwick Variable reluctance machines
US6022884A (en) * 1997-11-07 2000-02-08 Amgen Inc. Substituted pyridine compounds and methods of use

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1064259A (en) * 1963-12-19 1967-04-05 Union Pharma Scient Appl New derivatives of 2-anilino-nicotinic acid and process for their preparation
GB1162287A (en) * 1967-11-07 1969-08-20 Union Pharma Scient Appl New Salts of 2-Anilino-Nicotinic Acids
GB1264798A (da) * 1968-07-10 1972-02-23
ES416847A1 (es) * 1973-07-12 1976-03-01 Hermes Sa Lab Procedimiento para la obtencion de derivados del acido ni- cotinico.

Also Published As

Publication number Publication date
AT370415B (de) 1983-03-25
FI71555C (fi) 1987-01-19
ES480623A1 (es) 1980-01-01
ES475456A1 (es) 1979-05-01
FI782039A (fi) 1979-02-11
AU3877278A (en) 1980-02-14
NL7808319A (nl) 1979-02-13
NO782707L (no) 1979-02-13
DK148019B (da) 1985-02-04
NO152605B (no) 1985-07-15
IT1107960B (it) 1985-12-02
PT68407A (de) 1978-09-01
PL115778B1 (en) 1981-04-30
IE781618L (en) 1979-02-10
ES475457A1 (es) 1979-11-16
ZA784501B (en) 1980-04-30
ES472143A1 (es) 1979-03-16
FI71555B (fi) 1986-10-10
MX5672E (es) 1983-12-08
LU80094A1 (de) 1979-09-07
YU191678A (en) 1983-01-21
GR65024B (en) 1980-06-16
NO152605C (no) 1985-10-23
SE7808530L (sv) 1979-02-11
DE2735919A1 (de) 1979-02-22
AU520240B2 (en) 1982-01-21
YU40832B (en) 1986-06-30
FR2400017A1 (fr) 1979-03-09
BE869640A (fr) 1979-02-09
DD140351A5 (de) 1980-02-27
US4241068A (en) 1980-12-23
IT7850642A0 (it) 1978-08-08
SU886743A3 (ru) 1981-11-30
JPS5430177A (en) 1979-03-06
HU179933B (en) 1983-01-28
SU735168A3 (ru) 1980-05-15
ATA549278A (de) 1982-08-15
DK351978A (da) 1979-02-11
FR2400017B1 (da) 1983-03-11
ES480622A1 (es) 1980-01-01
JPS6231704B2 (da) 1987-07-09
CA1111037A (en) 1981-10-20
CH649289A5 (de) 1985-05-15
DE2735919C2 (da) 1988-10-27
PH19117A (en) 1986-01-06
GB2002764A (en) 1979-02-28
CS202506B2 (en) 1981-01-30
PL208942A1 (da) 1979-12-03
PL115889B1 (en) 1981-05-30
GB2002764B (en) 1982-08-04
SE444170B (sv) 1986-03-24
BG30472A1 (en) 1981-06-15
IE47228B1 (en) 1984-01-25
NZ188101A (en) 1981-01-23

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DK148019C (da) Analogifremgangsmaade til fremstilling af 2-pyridylaminobenzoesyrer eller farmaceutisk acceptable salte deraf

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PBP Patent lapsed