DK149269C - Analogifremgangsmaade til fremstilling af beta-mono- eller -difluormethyl-beta-alanin-derivater eller farmaceutisk acceptable salte eller optiske isomere deraf - Google Patents
Analogifremgangsmaade til fremstilling af beta-mono- eller -difluormethyl-beta-alanin-derivater eller farmaceutisk acceptable salte eller optiske isomere derafInfo
- Publication number
- DK149269C DK149269C DK320680A DK320680A DK149269C DK 149269 C DK149269 C DK 149269C DK 320680 A DK320680 A DK 320680A DK 320680 A DK320680 A DK 320680A DK 149269 C DK149269 C DK 149269C
- Authority
- DK
- Denmark
- Prior art keywords
- beta
- difluormethyl
- analogue
- mono
- preparation
- Prior art date
Links
- 230000003287 optical effect Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C229/20—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated the carbon skeleton being further substituted by halogen atoms or by nitro or nitroso groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C227/04—Formation of amino groups in compounds containing carboxyl groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB7926030 | 1979-07-26 | ||
| GB7926030 | 1979-07-26 | ||
| GB8002553 | 1980-01-25 | ||
| GB8002553 | 1980-01-25 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| DK320680A DK320680A (da) | 1981-01-27 |
| DK149269B DK149269B (da) | 1986-04-14 |
| DK149269C true DK149269C (da) | 1986-08-25 |
Family
ID=26272327
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK320680A DK149269C (da) | 1979-07-26 | 1980-07-24 | Analogifremgangsmaade til fremstilling af beta-mono- eller -difluormethyl-beta-alanin-derivater eller farmaceutisk acceptable salte eller optiske isomere deraf |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US4375477A (da) |
| EP (1) | EP0024965B1 (da) |
| AU (1) | AU536371B2 (da) |
| CA (1) | CA1161450A (da) |
| DE (1) | DE3062893D1 (da) |
| DK (1) | DK149269C (da) |
| ES (1) | ES493555A0 (da) |
| NO (1) | NO151319C (da) |
| NZ (1) | NZ194348A (da) |
| PH (1) | PH16349A (da) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL60591A (en) * | 1979-07-26 | 1985-02-28 | Merrell Toraude & Co | Alkenyl fluoromethyl ketimine magnesium halides and process for their preparation |
| GB2083030B (en) * | 1980-08-23 | 1984-03-07 | Merrell Toraude & Co | Fluorinated pentene diamine derivatives |
| GB2082578B (en) * | 1980-08-23 | 1984-05-23 | Merrell Toraude & Co | Fluorinated amino-butyric acid and diaminobutane derivatives |
| US4518528A (en) * | 1983-05-19 | 1985-05-21 | Rasnick David W | α Amino fluoro ketones |
| EP0353732A3 (de) * | 1988-08-05 | 1991-11-06 | Ciba-Geigy Ag | Neue Fluorolefine, Verfahren zu deren Herstellung und deren Verwendung |
| IL126999A (en) | 1996-07-24 | 2002-03-10 | Warner Lambert Co | Pharmaceutical preparations containing isobutylgaba and its history for use in the treatment of pain |
| US6306909B1 (en) * | 1997-03-12 | 2001-10-23 | Queen's University At Kingston | Anti-epileptogenic agents |
| US6541520B1 (en) * | 1998-08-05 | 2003-04-01 | Brookhaven Science Associates | Treatment of addiction and addiction-related behavior |
| MXPA03008164A (es) * | 2001-03-13 | 2003-12-12 | Univ Kingston | Agentes anti-epileptogenos. |
| US20030032579A1 (en) * | 2001-04-20 | 2003-02-13 | Pfizer Inc. | Therapeutic use of selective PDE10 inhibitors |
| JP2004536071A (ja) * | 2001-05-25 | 2004-12-02 | クイーンズ ユニバーシティ アット キングストン | 複素環ベータアミノ酸およびそれらの抗癲癇誘発剤としての使用 |
| US20040014143A1 (en) * | 2002-05-29 | 2004-01-22 | Haskins William E. | Method and apparatus for detecting and monitoring peptides, and peptides identified therewith |
| EP2948139B1 (en) | 2013-01-28 | 2019-06-12 | Lopez, Hector, L. | Methods of improving tolerability, pharmacodynamics, and efficacy of b-alanine and use therefor |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2662915A (en) * | 1952-06-30 | 1953-12-15 | Du Pont | Alpha-amino acids containing alpha, fluorinated-alkyl or cycloalkyl groups |
| JPS5225458Y2 (da) * | 1971-05-17 | 1977-06-10 | ||
| US3972921A (en) * | 1974-11-08 | 1976-08-03 | Merck & Co., Inc. | Synthesis of racemic 2-deutero-3-fluoro-alanine and its salts |
| SE7511733L (sv) * | 1974-11-08 | 1976-05-10 | Merck & Co Inc | Syntes av recemisk 3-fluoro-alanin och salter derav, samt mellanprodukt i denna syntes |
| IE47542B1 (en) * | 1977-06-01 | 1984-04-18 | Merck & Co Inc | Di-and tri-fluoromethyl amino acids and amines,compositions and processes for preparing said compounds |
| IE46910B1 (en) * | 1977-06-01 | 1983-11-02 | Merck & Co Inc | Fluorinated alkylamines and process for preparing same |
| US4326071A (en) | 1977-09-28 | 1982-04-20 | Merrell Toraude Et Compagnie | Halomethyl derivatives of gamma-aminobutyric acid and related compounds |
| US4264590A (en) * | 1979-05-23 | 1981-04-28 | Abbott Laboratories | Antibacterial peptide |
-
1980
- 1980-06-15 NZ NZ194348A patent/NZ194348A/xx unknown
- 1980-07-15 CA CA000356187A patent/CA1161450A/en not_active Expired
- 1980-07-17 AU AU60476/80A patent/AU536371B2/en not_active Ceased
- 1980-07-21 US US06/170,396 patent/US4375477A/en not_active Expired - Lifetime
- 1980-07-21 ES ES493555A patent/ES493555A0/es active Granted
- 1980-07-23 NO NO802218A patent/NO151319C/no unknown
- 1980-07-24 PH PH24344A patent/PH16349A/en unknown
- 1980-07-24 DK DK320680A patent/DK149269C/da not_active IP Right Cessation
- 1980-07-25 DE DE8080401107T patent/DE3062893D1/de not_active Expired
- 1980-07-25 EP EP80401107A patent/EP0024965B1/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| NZ194348A (en) | 1982-09-14 |
| DE3062893D1 (en) | 1983-06-01 |
| EP0024965B1 (en) | 1983-04-27 |
| DK320680A (da) | 1981-01-27 |
| ES8105969A1 (es) | 1981-07-01 |
| DK149269B (da) | 1986-04-14 |
| NO802218L (no) | 1981-01-27 |
| US4375477A (en) | 1983-03-01 |
| CA1161450A (en) | 1984-01-31 |
| EP0024965A1 (en) | 1981-03-11 |
| PH16349A (en) | 1983-09-05 |
| AU6047680A (en) | 1981-02-05 |
| AU536371B2 (en) | 1984-05-03 |
| ES493555A0 (es) | 1981-07-01 |
| NO151319C (no) | 1985-03-20 |
| NO151319B (no) | 1984-12-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PBP | Patent lapsed |