DK1427734T3 - Glycin-substituerede thieno[2,3-d]pydimidiner med kombineret LH- og FSH-agonistisk aktivitet - Google Patents

Glycin-substituerede thieno[2,3-d]pydimidiner med kombineret LH- og FSH-agonistisk aktivitet

Info

Publication number
DK1427734T3
DK1427734T3 DK02797646T DK02797646T DK1427734T3 DK 1427734 T3 DK1427734 T3 DK 1427734T3 DK 02797646 T DK02797646 T DK 02797646T DK 02797646 T DK02797646 T DK 02797646T DK 1427734 T3 DK1427734 T3 DK 1427734T3
Authority
DK
Denmark
Prior art keywords
pydimidines
glycine
combined
agonistic activity
substituted thieno
Prior art date
Application number
DK02797646T
Other languages
English (en)
Inventor
Robert Gerard Jules Ma Hanssen
Cornelis Marius Timmers
Jan Kelder
Original Assignee
Akzo Nobel Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo Nobel Nv filed Critical Akzo Nobel Nv
Application granted granted Critical
Publication of DK1427734T3 publication Critical patent/DK1427734T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
    • A61P5/08—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH for decreasing, blocking or antagonising the activity of the anterior pituitary hormones

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Reproductive Health (AREA)
  • Diabetes (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK02797646T 2001-09-04 2002-08-29 Glycin-substituerede thieno[2,3-d]pydimidiner med kombineret LH- og FSH-agonistisk aktivitet DK1427734T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP01203328 2001-09-04

Publications (1)

Publication Number Publication Date
DK1427734T3 true DK1427734T3 (da) 2006-03-06

Family

ID=8180877

Family Applications (1)

Application Number Title Priority Date Filing Date
DK02797646T DK1427734T3 (da) 2001-09-04 2002-08-29 Glycin-substituerede thieno[2,3-d]pydimidiner med kombineret LH- og FSH-agonistisk aktivitet

Country Status (27)

Country Link
US (1) US7375109B2 (da)
EP (1) EP1427734B1 (da)
JP (1) JP4263094B2 (da)
KR (1) KR100891630B1 (da)
CN (1) CN1261437C (da)
AR (1) AR036408A1 (da)
AT (1) ATE309251T1 (da)
AU (1) AU2002333750B2 (da)
BR (1) BR0212173A (da)
CA (1) CA2457212C (da)
CY (1) CY1106052T1 (da)
DE (1) DE60207280T2 (da)
DK (1) DK1427734T3 (da)
EC (1) ECSP044990A (da)
ES (1) ES2252540T3 (da)
HR (1) HRP20040194A2 (da)
HU (1) HUP0401443A3 (da)
IL (2) IL160194A0 (da)
IS (1) IS2419B (da)
MX (1) MXPA04002046A (da)
NO (1) NO328792B1 (da)
NZ (1) NZ531375A (da)
PE (1) PE20030467A1 (da)
PL (1) PL368388A1 (da)
RU (1) RU2294331C2 (da)
WO (1) WO2003020727A1 (da)
ZA (1) ZA200401459B (da)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6890923B2 (en) * 2002-12-16 2005-05-10 Astrazeneca Ab Compounds
KR100666484B1 (ko) * 2005-02-04 2007-01-09 삼성전자주식회사 반도체 메모리 장치의 입출력 회로 및 입출력 방법
US8741259B2 (en) * 2008-10-20 2014-06-03 Marvin C. Gershengorn Low molecular weight thyroid stimulating hormone receptor (TSHR) agonists
CN101762915B (zh) * 2008-12-24 2013-04-17 北京京东方光电科技有限公司 Tft-lcd阵列基板及其驱动方法
CN102791705B (zh) 2010-04-08 2016-08-03 美国政府(由卫生和人类服务部的部长所代表) 用于tsh受体的反向激动剂和中性拮抗剂
SI2900675T1 (sl) 2012-09-28 2019-06-28 Takeda Pharmaceutical Company Limited Postopek za pridobivanje tienopirimidin derivata

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2054784T3 (es) 1987-08-08 1994-08-16 Akzo Nv Un metodo para la fabricacion de un implante.
TW564247B (en) * 1999-04-08 2003-12-01 Akzo Nobel Nv Bicyclic heteraromatic compound

Also Published As

Publication number Publication date
US7375109B2 (en) 2008-05-20
DE60207280T2 (de) 2006-05-18
RU2294331C2 (ru) 2007-02-27
CN1261437C (zh) 2006-06-28
BR0212173A (pt) 2004-07-20
NO328792B1 (no) 2010-05-18
ECSP044990A (es) 2004-04-28
DE60207280D1 (de) 2005-12-15
AR036408A1 (es) 2004-09-08
JP2005504784A (ja) 2005-02-17
CA2457212A1 (en) 2003-03-13
CY1106052T1 (el) 2011-04-06
US20040180907A1 (en) 2004-09-16
IS2419B (is) 2008-10-15
IS7152A (is) 2004-02-13
PL368388A1 (en) 2005-03-21
HRP20040194A2 (en) 2004-08-31
IL160194A0 (en) 2004-07-25
NO20040922L (no) 2004-03-03
WO2003020727A1 (en) 2003-03-13
HUP0401443A2 (hu) 2004-11-29
IL160194A (en) 2009-06-15
AU2002333750B2 (en) 2008-02-21
KR20040029135A (ko) 2004-04-03
KR100891630B1 (ko) 2009-04-03
ES2252540T3 (es) 2006-05-16
CA2457212C (en) 2011-02-15
NZ531375A (en) 2005-06-24
PE20030467A1 (es) 2003-05-26
CN1551883A (zh) 2004-12-01
RU2004110036A (ru) 2005-10-10
HUP0401443A3 (en) 2008-05-28
MXPA04002046A (es) 2004-07-16
EP1427734A1 (en) 2004-06-16
EP1427734B1 (en) 2005-11-09
ATE309251T1 (de) 2005-11-15
JP4263094B2 (ja) 2009-05-13
ZA200401459B (en) 2004-11-22

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