DK1101756T3 - Aminopyrrolinderivater, fremgangsmåder til fremstilling heraf og farmaceutiske sammensætninger indeholdende disse - Google Patents

Aminopyrrolinderivater, fremgangsmåder til fremstilling heraf og farmaceutiske sammensætninger indeholdende disse

Info

Publication number
DK1101756T3
DK1101756T3 DK00403106T DK00403106T DK1101756T3 DK 1101756 T3 DK1101756 T3 DK 1101756T3 DK 00403106 T DK00403106 T DK 00403106T DK 00403106 T DK00403106 T DK 00403106T DK 1101756 T3 DK1101756 T3 DK 1101756T3
Authority
DK
Denmark
Prior art keywords
alkyl
derivatives
aryl
aminopyrroline
processes
Prior art date
Application number
DK00403106T
Other languages
English (en)
Inventor
Pascal Bousquet
Jean-Daniel Ehrhardt
Veronique Bruban
Josiane Feldman
Stephan Schann
Elizabeth Scalbert
Bruno Pfeiffer
Pierre Renard
Original Assignee
Servier Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Servier Lab filed Critical Servier Lab
Application granted granted Critical
Publication of DK1101756T3 publication Critical patent/DK1101756T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
    • C07D207/09—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/14—Nitrogen atoms not forming part of a nitro radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/40—Nitrogen atoms, not forming part of a nitro radical, e.g. isatin semicarbazone
DK00403106T 1999-11-17 2000-11-09 Aminopyrrolinderivater, fremgangsmåder til fremstilling heraf og farmaceutiske sammensætninger indeholdende disse DK1101756T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9914434A FR2801051B1 (fr) 1999-11-17 1999-11-17 Nouveaux composes aminopyrroline, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Publications (1)

Publication Number Publication Date
DK1101756T3 true DK1101756T3 (da) 2003-07-14

Family

ID=9552203

Family Applications (1)

Application Number Title Priority Date Filing Date
DK00403106T DK1101756T3 (da) 1999-11-17 2000-11-09 Aminopyrrolinderivater, fremgangsmåder til fremstilling heraf og farmaceutiske sammensætninger indeholdende disse

Country Status (23)

Country Link
US (1) US6300366B1 (da)
EP (1) EP1101756B1 (da)
JP (1) JP3274456B2 (da)
KR (1) KR100453981B1 (da)
CN (1) CN1158257C (da)
AT (1) ATE234815T1 (da)
AU (1) AU771745B2 (da)
BR (1) BR0005442A (da)
CA (1) CA2325781C (da)
DE (1) DE60001706T2 (da)
DK (1) DK1101756T3 (da)
EA (1) EA004042B1 (da)
ES (1) ES2194691T3 (da)
FR (1) FR2801051B1 (da)
HK (1) HK1036454A1 (da)
HU (1) HUP0004543A3 (da)
MX (1) MXPA00011239A (da)
NO (1) NO317987B1 (da)
NZ (1) NZ508228A (da)
PL (1) PL343920A1 (da)
PT (1) PT1101756E (da)
SI (1) SI1101756T1 (da)
ZA (1) ZA200006731B (da)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL372695A1 (en) 2002-06-19 2005-07-25 Solvay Pharmaceuticals Gmbh Medicament for the treatment of diseases requiring inhibition or a reduction in the activity of ph value-regulating bicarbonate transporter proteins
GB0521083D0 (en) * 2005-10-17 2005-11-23 Novartis Ag Organic compounds
IL280864B2 (en) 2013-08-09 2024-03-01 Ardelyx Inc Compounds and methods for inhibiting phosphate transport
GB201318886D0 (en) * 2013-10-25 2013-12-11 Givaudan Sa Improvements i or relating to organic compounds
CN114716359B (zh) * 2022-04-28 2023-01-17 广东医科大学 一种氢化吲哚亚胺非对映异构体的制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2029297A1 (de) * 1970-06-13 1971-12-30 Farbenfabriken Bayer Ag, 5090 Leverkusen Neue Aminophenyl-cycloamidine, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
US3887569A (en) * 1970-10-30 1975-06-03 Mcneilab Inc 2-Imino-piperidines
NL7412695A (nl) * 1974-09-26 1976-03-30 Stamicarbon De bereiding van een 2-amino-pyrrolinederivaat.
US4579951A (en) * 1984-03-19 1986-04-01 G. D. Searle & Co. Substituted (azacycloalk-2-yl)iminophenols and esters thereof
DE4425070A1 (de) * 1994-07-15 1996-01-18 Degussa Verfahren zur Herstellung optisch aktiver l-substituierter 2-(Aminomethyl)pyrrolidine

Also Published As

Publication number Publication date
US6300366B1 (en) 2001-10-09
KR20010051776A (ko) 2001-06-25
HUP0004543A3 (en) 2001-11-28
EP1101756A1 (fr) 2001-05-23
CA2325781C (fr) 2006-07-18
AU7168000A (en) 2001-05-24
PT1101756E (pt) 2003-06-30
MXPA00011239A (es) 2002-05-23
SI1101756T1 (en) 2003-06-30
EP1101756B1 (fr) 2003-03-19
ATE234815T1 (de) 2003-04-15
JP3274456B2 (ja) 2002-04-15
CN1298872A (zh) 2001-06-13
ZA200006731B (en) 2001-05-30
HU0004543D0 (da) 2001-02-28
HUP0004543A2 (hu) 2001-10-28
FR2801051A1 (fr) 2001-05-18
CN1158257C (zh) 2004-07-21
PL343920A1 (en) 2001-05-21
EA200001077A2 (ru) 2001-06-25
EA004042B1 (ru) 2003-12-25
ES2194691T3 (es) 2003-12-01
BR0005442A (pt) 2001-07-03
NZ508228A (en) 2001-03-30
NO20005797D0 (no) 2000-11-16
KR100453981B1 (ko) 2004-10-20
JP2001139545A (ja) 2001-05-22
EA200001077A3 (ru) 2001-08-27
CA2325781A1 (fr) 2001-05-17
DE60001706T2 (de) 2004-02-05
DE60001706D1 (de) 2003-04-24
HK1036454A1 (en) 2002-01-04
FR2801051B1 (fr) 2001-12-14
NO317987B1 (no) 2005-01-17
AU771745B2 (en) 2004-04-01
NO20005797L (no) 2001-05-18

Similar Documents

Publication Publication Date Title
TW200724136A (en) Pharmaceutical compositions comprising PPAR modulator
AR034268A1 (es) Compuestos derivados de piperidina, su uso en preparacion de medicamentos, composicion farmaceutica, metodo de tratamiento y proceso para su preparacion
KR950014097A (ko) 피페라진 유도체
HUP9802694A1 (hu) Benzamidszármazékok, eljárás előállításukra és ezeket tartalmazó gyógyszerkészítmények
HUP0400888A2 (hu) Helyettesített ciklohexán-1,4-diamin-származékok, eljárás az előállításukra és ezeket tartalmazó gyógyszerkészítmények
NO20053335L (no) 2-aminokarbonyl-kinolinforbindelser som blodplateadenosindifosfatreseptorer.
HUP0201475A2 (hu) Heteroarilamidin-, metilamidin- és guanidinszármazékok, előállításuk és alkalmazásuk, valamint e vegyületeket tartalmazó gyógyászati készítmények
ATE482933T1 (de) Sulfopyrrolderivate
DK1101756T3 (da) Aminopyrrolinderivater, fremgangsmåder til fremstilling heraf og farmaceutiske sammensætninger indeholdende disse
ATE300542T1 (de) 1-glyoxlylamidindolizine zur behandlung von krebs
DK492288A (da) Amidforbindelser, farmaceutisk praeparat indeholdende samme samt fremgangsmaade til fremstilling af forbindelserne
HUP0303361A2 (hu) Helyettesített 1-amino-bután-3-ol-származékok, eljárás az előállításukra és ezeket tartalmazó gyógyszerkészítmények
MXPA04005837A (es) Nuevos derivados de benzotiazina y benzotiadiazina, metodo para su preparacion y composiciones farmaceuticas que los contienen.
HUP0301008A2 (hu) Új imidazolszármazékok, eljárás az előállításukra, alkalmazásuk és ezeket tartalmazó gyógyszerkészítmények
TW200510309A (en) Chemical compounds
DK1042326T3 (da) Nye acronycinderivater, fremgangsmåde til fremstilling heraf og farmaceutiske sammensætninger, som indeholder disse
HUP9702149A2 (hu) Tachykinin receptor antagonista heterociklikus piperazinonszármazékok, intermedierjeik, előállításuk és alkalmazásuk, valamint a vegyületeket tartalmazó gyógyászati készítmények
BG106048A (en) 6-[[(aryl and heteroaryl)oxy]methyl]naphthalene-2-carboximidamide derivatives, preparation and therapeutic application thereof
HUP0204444A2 (en) Phenyl- and pyridyl-tetrahydro-pyridines, process for their preparation and pharmaceutical compositions containing them
DK0841337T3 (da) Substituerede 7,12-dioxabenzo[a]anthracenderivater, fremgangsmåde til fremstilling heraf og farmaceutiske sammensætninger, der indeholder disse derivater
DK0916671T3 (da) Metalloprotease-inhibitorer, fremgangsmåde til fremstilling heraf og farmaceutiske sammensætniger indeholdende sådanne inhibitorer
DK0982308T3 (da) Derivater af 8H-[2,3-b]pyrrolizin-8-on, fremgangsmåde til fremstilling heraf og farmaceutiske sammensætninger, som indeholder disse
MXPA04011363A (es) Nuevos derivados acil hidrazino del tiofeno, su procedimiento de preparacion, su aplicacion como medicamentos, composiciones farmaceuticas y nueva utilizacion.
NO955071L (no) abeo-Ergolin-derivater som 5HT1A-ligander