GB0521083D0 - Organic compounds - Google Patents

Organic compounds

Info

Publication number
GB0521083D0
GB0521083D0 GBGB0521083.6A GB0521083A GB0521083D0 GB 0521083 D0 GB0521083 D0 GB 0521083D0 GB 0521083 A GB0521083 A GB 0521083A GB 0521083 D0 GB0521083 D0 GB 0521083D0
Authority
GB
United Kingdom
Prior art keywords
organic compounds
compounds
organic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
GBGB0521083.6A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Novartis AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=35451886&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=GB0521083(D0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis AG filed Critical Novartis AG
Priority to GBGB0521083.6A priority Critical patent/GB0521083D0/en
Publication of GB0521083D0 publication Critical patent/GB0521083D0/en
Priority to ARP060104497A priority patent/AR058089A1/en
Priority to JO2006369A priority patent/JO2926B1/en
Priority to US12/088,457 priority patent/US7772405B2/en
Priority to DK06828821.6T priority patent/DK1948643T3/en
Priority to PL06828821T priority patent/PL1948643T3/en
Priority to PE2011001455A priority patent/PE20120581A1/en
Priority to CA2625034A priority patent/CA2625034C/en
Priority to RU2008119276/04A priority patent/RU2432354C2/en
Priority to BRPI0617492-2A priority patent/BRPI0617492A2/en
Priority to CN201210566662.6A priority patent/CN103121995B/en
Priority to ES06828821T priority patent/ES2427098T3/en
Priority to PE2006001252A priority patent/PE20070792A1/en
Priority to NZ567042A priority patent/NZ567042A/en
Priority to PCT/EP2006/009970 priority patent/WO2007045420A2/en
Priority to TW095138055A priority patent/TWI395733B/en
Priority to AU2006303489A priority patent/AU2006303489B2/en
Priority to JP2008535948A priority patent/JP5356031B2/en
Priority to CA2829487A priority patent/CA2829487A1/en
Priority to CN2006800035979A priority patent/CN101111493B/en
Priority to PT68288216T priority patent/PT1948643E/en
Priority to EP06828821.6A priority patent/EP1948643B1/en
Priority to SI200631641T priority patent/SI1948643T1/en
Priority to KR1020087009098A priority patent/KR101294432B1/en
Priority to IL190330A priority patent/IL190330A/en
Priority to ZA200802632A priority patent/ZA200802632B/en
Priority to EC2008008368A priority patent/ECSP088368A/en
Priority to MYPI20081108A priority patent/MY145466A/en
Priority to TNP2008000170A priority patent/TNSN08170A1/en
Priority to NO20082263A priority patent/NO342854B1/en
Priority to HK08113800.5A priority patent/HK1120509A1/en
Priority to US12/823,699 priority patent/US8198465B2/en
Priority to JP2012213001A priority patent/JP5792139B2/en
Priority to HRP20130793TT priority patent/HRP20130793T1/en
Priority to CY20131100754T priority patent/CY1114308T1/en
Priority to JP2014105430A priority patent/JP2014196312A/en
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/26—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D307/30—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/32—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06—Esters of carbamic acids
    • C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C271/22—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/26—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D307/30—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/32—Oxygen atoms
    • C07D307/33—Oxygen atoms in position 2, the oxygen atom being in its keto or unsubstituted enol form
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Furan Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Hydrogenated Pyridines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Peptides Or Proteins (AREA)
  • Indole Compounds (AREA)
GBGB0521083.6A 2005-10-17 2005-10-17 Organic compounds Ceased GB0521083D0 (en)

Priority Applications (36)

Application Number Priority Date Filing Date Title
GBGB0521083.6A GB0521083D0 (en) 2005-10-17 2005-10-17 Organic compounds
ARP060104497A AR058089A1 (en) 2005-10-17 2006-10-13 LACTAMA LACTAMA COMPOUNDS
JO2006369A JO2926B1 (en) 2005-10-17 2006-10-15 Organic Compounds
SI200631641T SI1948643T1 (en) 2005-10-17 2006-10-16 3-alkyl-5- (4-alkyl-5-oxo-tetrahydrofuran-2-yl) pyrrolidin-2-one derivatives as intermediates in the synthesis of renin inhibitors
KR1020087009098A KR101294432B1 (en) 2005-10-17 2006-10-16 3-alkyl-5-(4-alkyl-5-oxo-tetrahydrofuran-2-yl)pyrrolidin-2-one derivatives as intermediates in the synthesis of renin inhibitors
JP2008535948A JP5356031B2 (en) 2005-10-17 2006-10-16 3-Alkyl-5- (4-alkyl-5-oxo-tetrahydrofuran-2-yl) pyrrolidin-2-one derivatives as synthetic intermediates for renin inhibitors
PT68288216T PT1948643E (en) 2005-10-17 2006-10-16 3-alkyl-5- (4-alkyl-5-oxo-tetrahydrofuran-2-yl) pyrrolidin-2-one derivatives as intermediates in the synthesis of renin inhibitors
PL06828821T PL1948643T3 (en) 2005-10-17 2006-10-16 3-alkyl-5- (4-alkyl-5-oxo-tetrahydrofuran-2-yl) pyrrolidin-2-one derivatives as intermediates in the synthesis of renin inhibitors
PE2011001455A PE20120581A1 (en) 2005-10-17 2006-10-16 LACTAMA LACTONE DERIVATIVES AS INTERMEDIARIES IN THE SYNTHESIS OF RENIN INHIBITORS
CA2625034A CA2625034C (en) 2005-10-17 2006-10-16 3-alkyl-5-(4-alkyl-5-oxo-tetrahydrofutran-2-yl)pyrrolidin-2-one derivatives as intermediates in the synthesis of renin inhibitors
RU2008119276/04A RU2432354C2 (en) 2005-10-17 2006-10-16 Derivatives of 3-alkyl-5-(4-alkyl-5-oxotetrahydrofuran-2-yl)pyrrolidin-2-one as intermediate compounds in synthesis of renin inhibitors
BRPI0617492-2A BRPI0617492A2 (en) 2005-10-17 2006-10-16 3-alkyl-5- (4-alkyl-5-oxo-tetrahydro-furan-2-yl) pyrrolidin-2-one derivatives and method for their preparation
CN201210566662.6A CN103121995B (en) 2005-10-17 2006-10-16 3-alkyl-5-(4-alkyl-5-oXo-tetrahydro furan-2-base) pyrrolidin-2-one derivatives as the intermediate of synthesis renin inhibitor
ES06828821T ES2427098T3 (en) 2005-10-17 2006-10-16 3-alkyl-5- (4-alkyl-5-oxo-tetrahydrofuran-2-yl) -pyrrolidin-2-one derivatives as intermediates in the synthesis of renin inhibitors
PE2006001252A PE20070792A1 (en) 2005-10-17 2006-10-16 LACTAMA LACTONE DERIVATIVES AS INTERMEDIARIES IN THE SYNTHESIS OF RENIN INHIBITORS
NZ567042A NZ567042A (en) 2005-10-17 2006-10-16 Processes and intermediates for the prepration of aliskiren
PCT/EP2006/009970 WO2007045420A2 (en) 2005-10-17 2006-10-16 3-alkyl-5- (4-alkyl-5-oxo-tetrahydrofutran-2-yl) pyrrolidin-2-one derivatives as intermediates in the synthesis of renin inhibitors
TW095138055A TWI395733B (en) 2005-10-17 2006-10-16 Organic compounds
AU2006303489A AU2006303489B2 (en) 2005-10-17 2006-10-16 3-alkyl-5- (4-alkyl-5-oxo-tetrahydrofutran-2-yl) pyrrolidin-2-one derivatives as intermediates in the synthesis of renin inhibitors
US12/088,457 US7772405B2 (en) 2005-10-17 2006-10-16 3-alkyl-5- (4-alkyl-5-oxo-tetrahydrofutran-2-yl) pyrrolidin-2-one derivatives as intermediates in the synthesis of renin inhibitors
CA2829487A CA2829487A1 (en) 2005-10-17 2006-10-16 Organic compounds
CN2006800035979A CN101111493B (en) 2005-10-17 2006-10-16 3-alkyl-5- (4-alkyl-5-oxo-tetrahydrofutran-2-yl) pyrrolidin-2-one derivatives as intermediates in the synthesis of renin inhibitors
DK06828821.6T DK1948643T3 (en) 2005-10-17 2006-10-16 3-Alkyl-5- (4-alkyl-5-oxo-tetrahydrofuran-2-yl) pyrrolidin-2-one derivatives as intermediates in the synthesis of renin inhibitors
EP06828821.6A EP1948643B1 (en) 2005-10-17 2006-10-16 3-alkyl-5- (4-alkyl-5-oxo-tetrahydrofuran-2-yl) pyrrolidin-2-one derivatives as intermediates in the synthesis of renin inhibitors
IL190330A IL190330A (en) 2005-10-17 2008-03-20 3-alkyl-5-(4-alkyl-5-oxo-tetrahydrofuran-2-yl)pyrrolidin-2-one derivatives as intermediates in the synthesis of renin inhibitors
ZA200802632A ZA200802632B (en) 2005-10-17 2008-03-25 3-alkyl-5- (4-alkyl-5-oxo-tetrahydrofutran-2-yl) pyrrolidin-2-one derivatives as intermediates in the synthesis of renin inhibitors
MYPI20081108A MY145466A (en) 2005-10-17 2008-04-15 3-alkyl-5- (4-alkyl-5-oxo-tetrahydrofutran-2-yl) pyrrolidin-2-one derivatives as intermediates in the synthesis of renin inhibitors
EC2008008368A ECSP088368A (en) 2005-10-17 2008-04-15 DERIVATIVES OF 3-RENT-5- (4-RENT-5-OXO-TETRAHIDROFURAN-2-IL) -PIRROLIDIN-2-ONA AS INTERMEDIARIES IN THE SYNTHESIS OF RHININE INHIBITORS
TNP2008000170A TNSN08170A1 (en) 2005-10-17 2008-04-16 3-alkyl-5- (4-alkyl-5-oxo-tetrahydrofutran-2-yl) pyrrolidin-2-one derivatives as intermediates in the synthesis of renin inhibitors
NO20082263A NO342854B1 (en) 2005-10-17 2008-05-16 Intermediates in the synthesis of renin inhibitors, and process for their preparation.
HK08113800.5A HK1120509A1 (en) 2005-10-17 2008-12-19 3-alkyl-5- (4-alkyl-5-oxo-tetrahydrofuran-2-yl) pyrrolidin-2-one derivatives as intermediates in the synthesis of renin inhibitors
US12/823,699 US8198465B2 (en) 2005-10-17 2010-06-25 3-alkyl-5- (4-alkyl-5-oxo-tetrahydrofutran-2-yl) pyrrolidin-2-one derivatives as intermediates in the synthesis of renin inhibitors
JP2012213001A JP5792139B2 (en) 2005-10-17 2012-09-26 3-Alkyl-5- (4-alkyl-5-oxo-tetrahydrofuran-2-yl) pyrrolidin-2-one derivatives as synthetic intermediates for renin inhibitors
HRP20130793TT HRP20130793T1 (en) 2005-10-17 2013-08-22 3-alkyl-5- (4-alkyl-5-oxo-tetrahydrofuran-2-yl) pyrrolidin-2-one derivatives as intermediates in the synthesis of renin inhibitors
CY20131100754T CY1114308T1 (en) 2005-10-17 2013-09-02 Derivatives of 3-alkyl-5- (4-alkyl-5-oxo-tetrahydrofuran-2-yl) pyrrolidine-2-one as intermediate compounds at their current levels.
JP2014105430A JP2014196312A (en) 2005-10-17 2014-05-21 Derivative of 3-alkyl-5-(4-alkyl-5-oxo-tetrahydrofuran-2-yl)pyrrolidin-2-one as synthetic intermediate for renin inhibitor

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0521083.6A GB0521083D0 (en) 2005-10-17 2005-10-17 Organic compounds

Publications (1)

Publication Number Publication Date
GB0521083D0 true GB0521083D0 (en) 2005-11-23

Family

ID=35451886

Family Applications (1)

Application Number Title Priority Date Filing Date
GBGB0521083.6A Ceased GB0521083D0 (en) 2005-10-17 2005-10-17 Organic compounds

Country Status (30)

Country Link
US (2) US7772405B2 (en)
EP (1) EP1948643B1 (en)
JP (3) JP5356031B2 (en)
KR (1) KR101294432B1 (en)
CN (2) CN101111493B (en)
AR (1) AR058089A1 (en)
AU (1) AU2006303489B2 (en)
BR (1) BRPI0617492A2 (en)
CA (2) CA2829487A1 (en)
CY (1) CY1114308T1 (en)
DK (1) DK1948643T3 (en)
EC (1) ECSP088368A (en)
ES (1) ES2427098T3 (en)
GB (1) GB0521083D0 (en)
HK (1) HK1120509A1 (en)
HR (1) HRP20130793T1 (en)
IL (1) IL190330A (en)
JO (1) JO2926B1 (en)
MY (1) MY145466A (en)
NO (1) NO342854B1 (en)
NZ (1) NZ567042A (en)
PE (2) PE20120581A1 (en)
PL (1) PL1948643T3 (en)
PT (1) PT1948643E (en)
RU (1) RU2432354C2 (en)
SI (1) SI1948643T1 (en)
TN (1) TNSN08170A1 (en)
TW (1) TWI395733B (en)
WO (1) WO2007045420A2 (en)
ZA (1) ZA200802632B (en)

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Publication number Priority date Publication date Assignee Title
GB0521083D0 (en) * 2005-10-17 2005-11-23 Novartis Ag Organic compounds
DE102005052195A1 (en) * 2005-10-28 2007-05-03 Reuter Chemischer Apparatebau Kg Process for the preparation of chiral octenoic acid derivatives
CA2681203A1 (en) 2007-04-03 2008-10-09 Novartis Ag New methods
RU2010101236A (en) * 2007-06-19 2011-07-27 Новартис АГ (CH) ORGANIC COMPOUNDS
DE102007049039A1 (en) * 2007-10-11 2009-04-16 Reuter Chemischer Apparatebau Kg Process for the preparation of 8-hydrazino-8-aryl-octanoyl derivatives and their use
EP2189442B1 (en) * 2008-11-20 2014-10-01 Krka Tovarna Zdravil, D.D., Novo Mesto Process and intermediates for the preparation of aliskiren
WO2011019789A1 (en) * 2009-08-11 2011-02-17 Novartis Ag The ring opening of lactones and lactams
US8203005B2 (en) * 2009-10-29 2012-06-19 Carbo Design Llc Manufacturing process for enantiomerically pure 8-aryloctanoic acids as Aliskiren
US20110137047A1 (en) * 2009-12-07 2011-06-09 CarboDesign LLC Process for enantiomerically pure 8-Aryloctanoic acids as Aliskiren
CN101774986B (en) * 2010-01-06 2012-03-28 浙江天宇药业股份有限公司 Method for preparing aliskiren and intermediate thereof
CN102241650B (en) * 2010-05-14 2014-05-07 浙江九洲药业股份有限公司 Intermediate compound for preparing aliskiren and related preparation method
CN102485722B (en) * 2010-12-06 2014-05-07 博瑞生物医药技术(苏州)有限公司 Aliskiren, its intermediates and medicinal salt, as well as preparation method thereof
CN102775393B (en) * 2011-05-09 2014-08-27 上海现代制药股份有限公司 Preparation method for intermediate of medicine
US8703976B2 (en) 2011-10-02 2014-04-22 Milan Soukup Manufacturing process for 8-aryloctanoic acids such as Aliskiren
CN102746182B (en) * 2012-07-27 2014-09-03 浙江普洛医药科技有限公司 Preparation method of Aliskiren
CN103059012B (en) * 2013-01-30 2016-06-22 浙江海翔药业股份有限公司 1,8-dicarbapentaborane-4,5-epoxide and preparation method thereof
CN106220528B (en) * 2014-02-28 2018-05-08 华润双鹤药业股份有限公司 4- positions epimer, the preparation method and the usage of aliskiren
CN105294612A (en) * 2014-06-05 2016-02-03 山东威智医药工业有限公司 Aliskiren intermediate, and preparation method therefor and application thereof
US10087190B1 (en) * 2017-04-24 2018-10-02 Purdue Research Foundation Lactones
CN114315749B (en) * 2021-12-13 2024-04-26 湖南华腾医药有限公司 Method for synthesizing aliskiren intermediate by continuous flow microreactor

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MY119161A (en) 1994-04-18 2005-04-30 Novartis Ag Delta-amino-gamma-hydroxy-omega-aryl-alkanoic acid amides with enzyme especially renin inhibiting activities
US5659065A (en) 1994-04-18 1997-08-19 Novartis Corporation Alpha-aminoalkanoic acids and reduction products
DK1200384T3 (en) * 1999-07-29 2004-08-02 Speedel Pharma Ag 2-Alkyl-5-halo-pent-4-encarboxylic acids and their preparation
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GB0212410D0 (en) * 2002-05-29 2002-07-10 Novartis Ag Organic compounds
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Also Published As

Publication number Publication date
TNSN08170A1 (en) 2009-10-30
NO342854B1 (en) 2018-08-20
MY145466A (en) 2012-02-15
CN101111493A (en) 2008-01-23
CY1114308T1 (en) 2016-08-31
WO2007045420A3 (en) 2007-06-07
JP2013032369A (en) 2013-02-14
ECSP088368A (en) 2008-05-30
KR101294432B1 (en) 2013-08-07
JP5356031B2 (en) 2013-12-04
IL190330A (en) 2013-12-31
CA2625034C (en) 2014-08-19
RU2008119276A (en) 2009-11-27
TW200800965A (en) 2008-01-01
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