BR0005442A - Composições de aminopirrolina, processo para a sua preparação e composições farmacêuticas contendo os mesmos - Google Patents
Composições de aminopirrolina, processo para a sua preparação e composições farmacêuticas contendo os mesmosInfo
- Publication number
- BR0005442A BR0005442A BR0005442-9A BR0005442A BR0005442A BR 0005442 A BR0005442 A BR 0005442A BR 0005442 A BR0005442 A BR 0005442A BR 0005442 A BR0005442 A BR 0005442A
- Authority
- BR
- Brazil
- Prior art keywords
- sym
- preparation
- same
- group
- hydrogen atom
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- NPLSMQWSKZXZPD-UHFFFAOYSA-N 2,3-dihydropyrrol-1-amine Chemical compound NN1CCC=C1 NPLSMQWSKZXZPD-UHFFFAOYSA-N 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000004450 alkenylene group Chemical group 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000004453 alkoxycarbonyl group Chemical group 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- 125000004419 alkynylene group Chemical group 0.000 abstract 1
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 125000005160 aryl oxy alkyl group Chemical group 0.000 abstract 1
- 125000005549 heteroarylene group Chemical group 0.000 abstract 1
- 125000002768 hydroxyalkyl group Chemical group 0.000 abstract 1
- 125000005649 substituted arylene group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
- C07D207/09—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/14—Nitrogen atoms not forming part of a nitro radical
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/40—Nitrogen atoms, not forming part of a nitro radical, e.g. isatin semicarbazone
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Heart & Thoracic Surgery (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Cardiology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Indole Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Patente de Invenção: <B>"COMPOSTOS DE AMINOPIRROLINA, PROCESSO PARA A SUA PREPARAçãO E COMPOSIçõES FARMACêUTICAS CONTENDO OS MESMOS"<D>. Composto da fórmula (I); onde: <sym> n é 1 ou 2, <sym> X representa um grupo alquileno, alquenileno ou alquinileno, ou um grupo arileno ou heteroarileno opcionalmente substituído, <sym> R~ 10~ representa um átomo de hidrogênio ou um grupo alquila e R~ 11~ e R~ 12~ juntos formam uma ligação, ou alternativamente R~ 12~ representa um átomo de hidrogênio ou um grupo alquila e R~ 10~ e R~ 11~ juntos formam uma ligação, <sym> R~ 2~, R~ 3~ e R~ 4~ cada um independentemente dos outros representam um átomo de hidrogênio, um grupo alquila, hidroxialquila, alcóxi, alcoxicarbonila, arila, arilalquila ou ariloxialquila, ou dois de R~ 2~, R~ 3~ e R~ 4~ formam um radical cicloalquila.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9914434A FR2801051B1 (fr) | 1999-11-17 | 1999-11-17 | Nouveaux composes aminopyrroline, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR0005442A true BR0005442A (pt) | 2001-07-03 |
Family
ID=9552203
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR0005442-9A BR0005442A (pt) | 1999-11-17 | 2000-11-17 | Composições de aminopirrolina, processo para a sua preparação e composições farmacêuticas contendo os mesmos |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US6300366B1 (pt) |
| EP (1) | EP1101756B1 (pt) |
| JP (1) | JP3274456B2 (pt) |
| KR (1) | KR100453981B1 (pt) |
| CN (1) | CN1158257C (pt) |
| AT (1) | ATE234815T1 (pt) |
| AU (1) | AU771745B2 (pt) |
| BR (1) | BR0005442A (pt) |
| CA (1) | CA2325781C (pt) |
| DE (1) | DE60001706T2 (pt) |
| DK (1) | DK1101756T3 (pt) |
| EA (1) | EA004042B1 (pt) |
| ES (1) | ES2194691T3 (pt) |
| FR (1) | FR2801051B1 (pt) |
| HK (1) | HK1036454A1 (pt) |
| HU (1) | HUP0004543A3 (pt) |
| MX (1) | MXPA00011239A (pt) |
| NO (1) | NO317987B1 (pt) |
| NZ (1) | NZ508228A (pt) |
| PL (1) | PL343920A1 (pt) |
| PT (1) | PT1101756E (pt) |
| SI (1) | SI1101756T1 (pt) |
| ZA (1) | ZA200006731B (pt) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2487541A1 (en) | 2002-06-19 | 2003-12-31 | Solvay Pharmaceuticals Gmbh | Medicament for the treatment of diseases requiring inhibition or a reduction in the activity of ph value-regulating bicarbonate transporter proteins |
| GB0521083D0 (en) * | 2005-10-17 | 2005-11-23 | Novartis Ag | Organic compounds |
| AU2014305843B2 (en) | 2013-08-09 | 2019-08-29 | Ardelyx, Inc. | Compounds and methods for inhibiting phosphate transport |
| GB201318886D0 (en) * | 2013-10-25 | 2013-12-11 | Givaudan Sa | Improvements i or relating to organic compounds |
| CN114716359B (zh) * | 2022-04-28 | 2023-01-17 | 广东医科大学 | 一种氢化吲哚亚胺非对映异构体的制备方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2029297A1 (de) * | 1970-06-13 | 1971-12-30 | Farbenfabriken Bayer Ag, 5090 Leverkusen | Neue Aminophenyl-cycloamidine, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel |
| US3887569A (en) * | 1970-10-30 | 1975-06-03 | Mcneilab Inc | 2-Imino-piperidines |
| NL7412695A (nl) * | 1974-09-26 | 1976-03-30 | Stamicarbon | De bereiding van een 2-amino-pyrrolinederivaat. |
| US4579951A (en) * | 1984-03-19 | 1986-04-01 | G. D. Searle & Co. | Substituted (azacycloalk-2-yl)iminophenols and esters thereof |
| DE4425070A1 (de) * | 1994-07-15 | 1996-01-18 | Degussa | Verfahren zur Herstellung optisch aktiver l-substituierter 2-(Aminomethyl)pyrrolidine |
-
1999
- 1999-11-17 FR FR9914434A patent/FR2801051B1/fr not_active Expired - Fee Related
-
2000
- 2000-11-09 AT AT00403106T patent/ATE234815T1/de not_active IP Right Cessation
- 2000-11-09 EP EP00403106A patent/EP1101756B1/fr not_active Expired - Lifetime
- 2000-11-09 SI SI200030067T patent/SI1101756T1/xx unknown
- 2000-11-09 DE DE60001706T patent/DE60001706T2/de not_active Expired - Fee Related
- 2000-11-09 PT PT00403106T patent/PT1101756E/pt unknown
- 2000-11-09 DK DK00403106T patent/DK1101756T3/da active
- 2000-11-09 ES ES00403106T patent/ES2194691T3/es not_active Expired - Lifetime
- 2000-11-14 JP JP2000346838A patent/JP3274456B2/ja not_active Expired - Fee Related
- 2000-11-15 MX MXPA00011239A patent/MXPA00011239A/es active IP Right Grant
- 2000-11-16 US US09/714,090 patent/US6300366B1/en not_active Expired - Fee Related
- 2000-11-16 EA EA200001077A patent/EA004042B1/ru not_active IP Right Cessation
- 2000-11-16 PL PL00343920A patent/PL343920A1/xx not_active Application Discontinuation
- 2000-11-16 NZ NZ508228A patent/NZ508228A/xx unknown
- 2000-11-16 NO NO20005797A patent/NO317987B1/no unknown
- 2000-11-16 HU HU0004543A patent/HUP0004543A3/hu unknown
- 2000-11-17 BR BR0005442-9A patent/BR0005442A/pt not_active IP Right Cessation
- 2000-11-17 KR KR10-2000-0068434A patent/KR100453981B1/ko not_active IP Right Cessation
- 2000-11-17 ZA ZA200006731A patent/ZA200006731B/xx unknown
- 2000-11-17 AU AU71680/00A patent/AU771745B2/en not_active Ceased
- 2000-11-17 CN CNB001285394A patent/CN1158257C/zh not_active Expired - Fee Related
- 2000-11-17 CA CA002325781A patent/CA2325781C/fr not_active Expired - Fee Related
-
2001
- 2001-10-24 HK HK01107419A patent/HK1036454A1/xx not_active IP Right Cessation
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PC | Transfer |
Free format text: LES LABORATOIRES SERVIER (FR) |
|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 7A E 8A ANUIDADES. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 NA RPI2003 DE 26/05/2009. |