DK1002792T3 - 2-aminopropan-1,3-diolforbindelser, medicinsk anvendelse deraf og mellemprodukter til syntese af disse - Google Patents

2-aminopropan-1,3-diolforbindelser, medicinsk anvendelse deraf og mellemprodukter til syntese af disse

Info

Publication number: DK1002792T3
Authority: DK; Denmark
Prior art keywords: compound; aminopropane; intermediates; synthesis; drug
Prior art date: 1997-04-04

Application number

DK98911211T

Other languages

English (en)

Inventor

Kunitomo Adachi

Tokushi Hanano

Yukio Hoshino

Tetsuro Fujita

Yoshiyuki Aoki

Koji Teshima

Original Assignee

Mitsubishi Pharma Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-04-04

Filing date

1998-04-03

Publication date

2004-11-22

1998-04-03 Application filed by Mitsubishi Pharma Corp filed Critical Mitsubishi Pharma Corp

2004-11-22 Application granted granted Critical

2004-11-22 Publication of DK1002792T3 publication Critical patent/DK1002792T3/da

Links

KJJPLEZQSCZCKE-UHFFFAOYSA-N 2-aminopropane-1,3-diol Chemical class OCC(N)CO KJJPLEZQSCZCKE-UHFFFAOYSA-N 0.000 title 1
230000015572 biosynthetic process Effects 0.000 title 1
239000000543 intermediate Substances 0.000 title 1
238000003786 synthesis reaction Methods 0.000 title 1
150000001875 compounds Chemical class 0.000 abstract 4
239000003814 drug Substances 0.000 abstract 2
229940079593 drug Drugs 0.000 abstract 2
208000023275 Autoimmune disease Diseases 0.000 abstract 1
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
239000002253 acid Substances 0.000 abstract 1
125000002252 acyl group Chemical group 0.000 abstract 1
208000026935 allergic disease Diseases 0.000 abstract 1
238000010322 bone marrow transplantation Methods 0.000 abstract 1
239000003937 drug carrier Chemical class 0.000 abstract 1
229910052739 hydrogen Inorganic materials 0.000 abstract 1
239000001257 hydrogen Substances 0.000 abstract 1
230000001506 immunosuppresive effect Effects 0.000 abstract 1
210000000056 organ Anatomy 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1
230000002265 prevention Effects 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
230000001629 suppression Effects 0.000 abstract 1
230000001988 toxicity Effects 0.000 abstract 1
231100000419 toxicity Toxicity 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
- C07C255/01—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms
- C07C255/16—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms containing cyano groups and singly-bound oxygen atoms bound to the same carbon atom of an acyclic carbon skeleton
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C225/00—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones
- C07C225/02—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to acyclic carbon atoms of the carbon skeleton
- C07C225/14—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being unsaturated
- C07C225/16—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
- C07C215/02—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C215/22—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated
- C07C215/28—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings
- C07C215/34—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings containing hydroxy groups and carbon atoms of six-membered aromatic rings bound to the same carbon atom of the carbon skeleton and at least one hydroxy group bound to another carbon atom of the carbon skeleton
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C223/00—Compounds containing amino and —CHO groups bound to the same carbon skeleton
- C07C223/02—Compounds containing amino and —CHO groups bound to the same carbon skeleton having amino groups bound to acyclic carbon atoms of the carbon skeleton
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
- C07F7/1804—Compounds having Si-O-C linkages

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Immunology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Transplantation (AREA)
Pulmonology (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

DK98911211T 1997-04-04 1998-04-03 2-aminopropan-1,3-diolforbindelser, medicinsk anvendelse deraf og mellemprodukter til syntese af disse DK1002792T3 (da)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
JP8625597		1997-04-04
PCT/JP1998/001571 WO1998045249A1 (fr)	1997-04-04	1998-04-03	Composes 2-aminopropane-1,3-diol, leur utilisation pharmaceutique, et intermediaires servant a leur synthese
EP98911211A EP1002792B1 (en)	1997-04-04	1998-04-03	2-aminopropane-1,3-diol compounds, medicinal use thereof, and intermediates in synthesizing the same

Publications (1)

Publication Number	Publication Date
DK1002792T3 true DK1002792T3 (da)	2004-11-22

Family

ID=13881722

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
DK03003623T DK1319651T3 (da)	1997-04-04	1998-04-03	2-aminopropan-1,3-diolforbindelser, medicinsk anvendelse deraf og mellemprodukter til syntese af disse
DK98911211T DK1002792T3 (da)	1997-04-04	1998-04-03	2-aminopropan-1,3-diolforbindelser, medicinsk anvendelse deraf og mellemprodukter til syntese af disse

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
DK03003623T DK1319651T3 (da)	1997-04-04	1998-04-03	2-aminopropan-1,3-diolforbindelser, medicinsk anvendelse deraf og mellemprodukter til syntese af disse

Country Status (18)

Country	Link
US (2)	US6214873B1 (da)
EP (2)	EP1002792B1 (da)
JP (1)	JP4045364B2 (da)
KR (1)	KR100551931B1 (da)
CN (2)	CN1137086C (da)
AT (2)	ATE271028T1 (da)
AU (1)	AU735853B2 (da)
BR (1)	BR9808481A (da)
CA (1)	CA2286315C (da)
DE (2)	DE69830756T2 (da)
DK (2)	DK1319651T3 (da)
ES (2)	ES2226110T3 (da)
IL (3)	IL155066A (da)
NZ (1)	NZ500713A (da)
PT (2)	PT1319651E (da)
RU (1)	RU2198162C2 (da)
SI (2)	SI1319651T1 (da)
WO (1)	WO1998045249A1 (da)

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1998
- 1998-04-03 IL IL15506698A patent/IL155066A/en not_active IP Right Cessation
- 1998-04-03 SI SI9830785T patent/SI1319651T1/xx unknown
- 1998-04-03 BR BR9808481-0A patent/BR9808481A/pt active Search and Examination
- 1998-04-03 ES ES98911211T patent/ES2226110T3/es not_active Expired - Lifetime
- 1998-04-03 KR KR1019997009082A patent/KR100551931B1/ko not_active IP Right Cessation
- 1998-04-03 IL IL13220898A patent/IL132208A/xx not_active IP Right Cessation
- 1998-04-03 PT PT03003623T patent/PT1319651E/pt unknown
- 1998-04-03 NZ NZ500713A patent/NZ500713A/xx not_active IP Right Cessation
- 1998-04-03 DE DE69830756T patent/DE69830756T2/de not_active Expired - Lifetime
- 1998-04-03 PT PT98911211T patent/PT1002792E/pt unknown
- 1998-04-03 EP EP98911211A patent/EP1002792B1/en not_active Expired - Lifetime
- 1998-04-03 DE DE69825056T patent/DE69825056T2/de not_active Expired - Lifetime
- 1998-04-03 DK DK03003623T patent/DK1319651T3/da active
- 1998-04-03 WO PCT/JP1998/001571 patent/WO1998045249A1/ja active IP Right Grant
- 1998-04-03 CN CNB988058804A patent/CN1137086C/zh not_active Expired - Fee Related
- 1998-04-03 RU RU99123047/04A patent/RU2198162C2/ru not_active IP Right Cessation
- 1998-04-03 JP JP54259298A patent/JP4045364B2/ja not_active Expired - Fee Related
- 1998-04-03 CN CNB03136893XA patent/CN1290819C/zh not_active Expired - Fee Related
- 1998-04-03 AT AT98911211T patent/ATE271028T1/de active
- 1998-04-03 DK DK98911211T patent/DK1002792T3/da active
- 1998-04-03 CA CA002286315A patent/CA2286315C/en not_active Expired - Fee Related
- 1998-04-03 US US09/402,375 patent/US6214873B1/en not_active Ceased
- 1998-04-03 AT AT03003623T patent/ATE298740T1/de active
- 1998-04-03 AU AU65230/98A patent/AU735853B2/en not_active Ceased
- 1998-04-03 US US10/410,387 patent/USRE39072E1/en not_active Expired - Lifetime
- 1998-04-03 IL IL15506598A patent/IL155065A/en not_active IP Right Cessation
- 1998-04-03 EP EP03003623A patent/EP1319651B1/en not_active Expired - Lifetime
- 1998-04-03 ES ES03003623T patent/ES2240868T3/es not_active Expired - Lifetime
- 1998-04-03 SI SI9830698T patent/SI1002792T1/xx unknown

Also Published As

Publication number	Publication date
NZ500713A (en)	2000-07-28
IL155065A0 (en)	2003-10-31
EP1002792A4 (en)	2002-03-20
CN1290819C (zh)	2006-12-20
SI1002792T1 (en)	2004-12-31
CA2286315C (en)	2007-03-06
KR100551931B1 (ko)	2006-02-16
DE69825056T2 (de)	2005-08-25
AU6523098A (en)	1998-10-30
WO1998045249A1 (fr)	1998-10-15
IL132208A0 (en)	2001-03-19
CA2286315A1 (en)	1998-10-15
CN1137086C (zh)	2004-02-04
ES2240868T3 (es)	2005-10-16
JP4045364B2 (ja)	2008-02-13
BR9808481A (pt)	2000-05-23
DE69825056D1 (de)	2004-08-19
RU2198162C2 (ru)	2003-02-10
CN1259117A (zh)	2000-07-05
USRE39072E1 (en)	2006-04-18
SI1319651T1 (en)	2005-10-31
DE69830756D1 (de)	2005-08-04
ATE298740T1 (de)	2005-07-15
PT1002792E (pt)	2004-12-31
EP1319651B1 (en)	2005-06-29
IL155065A (en)	2004-01-04
EP1002792B1 (en)	2004-07-14
PT1319651E (pt)	2005-09-30
DK1319651T3 (da)	2005-08-01
KR20010006004A (ko)	2001-01-15
IL155066A (en)	2004-06-20
EP1002792A1 (en)	2000-05-24
IL132208A (en)	2003-07-31
ES2226110T3 (es)	2005-03-16
EP1319651A3 (en)	2004-01-02
IL155066A0 (en)	2003-10-31
EP1319651A2 (en)	2003-06-18
US6214873B1 (en)	2001-04-10
ATE271028T1 (de)	2004-07-15
DE69830756T2 (de)	2006-05-04
CN1480450A (zh)	2004-03-10
AU735853B2 (en)	2001-07-19

Publication	Publication Date	Title
DK1002792T3 (da)	2004-11-22	2-aminopropan-1,3-diolforbindelser, medicinsk anvendelse deraf og mellemprodukter til syntese af disse
ID27285A (id)	2001-03-22	Turunan benzamida untuk pengobatan penyakit yang diperantarai oleh sitokina
BR0008173A (pt)	2002-10-22	Composto de amida e seu uso como campo técnico de medicina da invenção
ATE353641T1 (de)	2007-03-15	Benzamide als kaliumkanal-inhibitoren
PT1063228E (pt)	2005-05-31	Derivados de cicloalcenos processo para a sua preparacao e utilizacao
BR9407711A (pt)	1997-02-12	Composto de ciclopeptídeo processo para preparaçao de um composto de ciclopeptídeo e parasiticida
DK0644199T3 (da)	2000-09-18	Cykliske antimikrobielle peptider og fremstilling deraf
HUT62296A (en)	1993-04-28	Herbicidal composition comprising hydantoin derivative as active ingredient and process for producing the active ingredient
DE60023008D1 (de)	2006-02-16	Mittel zur verhinderung der chronischen abstossreaktion infolge einer organtransplantation
DE68926981D1 (de)	1996-09-26	Cephemverbindungen und Verfahren zu ihrer Herstellung
DK0947513T3 (da)	2004-08-30	Tricykliske aminderivater
AU9233101A (en)	2002-04-15	5-amidino-2-hydroxybenzenesulfonamide derivatives, pharmaceutical compositions containing the same and intermediates for their preparation
DE69001004D1 (de)	1993-04-08	Zusammensetzung gegen leberkrankheiten.
ATE79752T1 (de)	1992-09-15	Verwendung von chromanderivaten zur herstellung eines medikamentes zur behandlung von depressiven zustaenden.
TH38253A (th)	2000-04-28	อนุพันธ์ 6,6-เฮเทอโร-ไบไซคลิคที่ถูกเข้าแทนที่