DK0826695T3 - Tilintetgørelse af kontaminerende tumorceller i stamcelletransplantater med bispecifikke antistoffer - Google Patents

Tilintetgørelse af kontaminerende tumorceller i stamcelletransplantater med bispecifikke antistoffer

Info

Publication number
DK0826695T3
DK0826695T3 DK97115188T DK97115188T DK0826695T3 DK 0826695 T3 DK0826695 T3 DK 0826695T3 DK 97115188 T DK97115188 T DK 97115188T DK 97115188 T DK97115188 T DK 97115188T DK 0826695 T3 DK0826695 T3 DK 0826695T3
Authority
DK
Denmark
Prior art keywords
stem cell
destruction
tumor cells
bispecific antibodies
cell grafts
Prior art date
Application number
DK97115188T
Other languages
English (en)
Inventor
Horst Dr Lindhofer
Helge Dr Menzel
Hans-Jochem Prof Dr Kolb
Stefan Prof Dr Thierfelder
Original Assignee
Gsf Forschungszentrum Umwelt
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19649223A external-priority patent/DE19649223C2/de
Application filed by Gsf Forschungszentrum Umwelt filed Critical Gsf Forschungszentrum Umwelt
Application granted granted Critical
Publication of DK0826695T3 publication Critical patent/DK0826695T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2809—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against the T-cell receptor (TcR)-CD3 complex
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/46—Hybrid immunoglobulins
    • C07K16/468—Immunoglobulins having two or more different antigen binding sites, e.g. multifunctional antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
DK97115188T 1996-09-03 1997-09-02 Tilintetgørelse af kontaminerende tumorceller i stamcelletransplantater med bispecifikke antistoffer DK0826695T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19635743 1996-09-03
DE19649223A DE19649223C2 (de) 1996-09-03 1996-11-27 Zerstörung von kontaminierenden Tumorzellen in Stammzelltransplantaten mit bispezifischen Antikörpern

Publications (1)

Publication Number Publication Date
DK0826695T3 true DK0826695T3 (da) 2002-04-15

Family

ID=26028996

Family Applications (1)

Application Number Title Priority Date Filing Date
DK97115188T DK0826695T3 (da) 1996-09-03 1997-09-02 Tilintetgørelse af kontaminerende tumorceller i stamcelletransplantater med bispecifikke antistoffer

Country Status (6)

Country Link
US (2) US5985276A (da)
EP (1) EP0826695B1 (da)
JP (1) JP3257970B2 (da)
AT (1) ATE210682T1 (da)
DK (1) DK0826695T3 (da)
ES (1) ES2169299T3 (da)

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Also Published As

Publication number Publication date
JPH10179151A (ja) 1998-07-07
ATE210682T1 (de) 2001-12-15
EP0826695B1 (de) 2001-12-12
JP3257970B2 (ja) 2002-02-18
EP0826695A1 (de) 1998-03-04
ES2169299T3 (es) 2002-07-01
US5985276A (en) 1999-11-16
US6210668B1 (en) 2001-04-03

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