PT699755E - Metodo para obtencao de imunoglobulinas modificadas com imunogenicidade reduzida de dominios variaveis de anticorpos de murideo composicoes que as contem - Google Patents

Metodo para obtencao de imunoglobulinas modificadas com imunogenicidade reduzida de dominios variaveis de anticorpos de murideo composicoes que as contem

Info

Publication number
PT699755E
PT699755E PT95201752T PT95201752T PT699755E PT 699755 E PT699755 E PT 699755E PT 95201752 T PT95201752 T PT 95201752T PT 95201752 T PT95201752 T PT 95201752T PT 699755 E PT699755 E PT 699755E
Authority
PT
Portugal
Prior art keywords
mammalian species
variable domains
antibodies
murideo
contain
Prior art date
Application number
PT95201752T
Other languages
English (en)
Inventor
Rolando Perez Rodriquez
Josefa Lombardero Valladares
Cristina Maria Mateo De Ac Rio
Original Assignee
Centro Inmunologia Molecular
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Centro Inmunologia Molecular filed Critical Centro Inmunologia Molecular
Publication of PT699755E publication Critical patent/PT699755E/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3007—Carcino-embryonic Antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2863—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/46—Hybrid immunoglobulins
    • C07K16/461—Igs containing Ig-regions, -domains or -residues form different species
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oncology (AREA)
  • Cell Biology (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Saccharide Compounds (AREA)
PT95201752T 1994-06-30 1995-06-27 Metodo para obtencao de imunoglobulinas modificadas com imunogenicidade reduzida de dominios variaveis de anticorpos de murideo composicoes que as contem PT699755E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CU1994080A CU22615A1 (es) 1994-06-30 1994-06-30 Procedimiento de obtención de anticuerpos monoclonales murinos menos inmunogénicos. anticuerpos monoclonales obtenidos

Publications (1)

Publication Number Publication Date
PT699755E true PT699755E (pt) 2004-09-30

Family

ID=5459314

Family Applications (1)

Application Number Title Priority Date Filing Date
PT95201752T PT699755E (pt) 1994-06-30 1995-06-27 Metodo para obtencao de imunoglobulinas modificadas com imunogenicidade reduzida de dominios variaveis de anticorpos de murideo composicoes que as contem

Country Status (11)

Country Link
US (1) US5712120A (pt)
EP (1) EP0699755B1 (pt)
JP (1) JP3238049B2 (pt)
CN (1) CN1279168C (pt)
AT (1) ATE265531T1 (pt)
CA (1) CA2153135C (pt)
CU (1) CU22615A1 (pt)
DE (1) DE69532940T2 (pt)
DK (1) DK0699755T3 (pt)
ES (1) ES2220918T3 (pt)
PT (1) PT699755E (pt)

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US5712120A (en) 1998-01-27
EP0699755B1 (en) 2004-04-28
JP3238049B2 (ja) 2001-12-10
DE69532940D1 (de) 2004-06-03
CN1133886A (zh) 1996-10-23
CA2153135C (en) 2005-06-07
DE69532940T2 (de) 2005-05-25
ATE265531T1 (de) 2004-05-15
ES2220918T3 (es) 2004-12-16
CU22615A1 (es) 2000-02-10
EP0699755A3 (en) 1996-06-12
JPH08280387A (ja) 1996-10-29
CN1279168C (zh) 2006-10-11
DK0699755T3 (da) 2004-08-30
CA2153135A1 (en) 1995-12-31
EP0699755A2 (en) 1996-03-06

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