DK0738269T5 - Piperidinderivater med PAF-antagonistaktivitet - Google Patents

Piperidinderivater med PAF-antagonistaktivitet

Info

Publication number
DK0738269T5
DK0738269T5 DK95932668T DK95932668T DK0738269T5 DK 0738269 T5 DK0738269 T5 DK 0738269T5 DK 95932668 T DK95932668 T DK 95932668T DK 95932668 T DK95932668 T DK 95932668T DK 0738269 T5 DK0738269 T5 DK 0738269T5
Authority
DK
Denmark
Prior art keywords
pct
antagonist activity
piperidine derivatives
paf antagonist
paf
Prior art date
Application number
DK95932668T
Other languages
English (en)
Other versions
DK0738269T3 (da
Inventor
Elena Carceller
Pere J Jimenez
Nuria Recasens
Jordi Salas
Carmen Almansa
Javier Bartroli
Original Assignee
Uriach & Cia Sa J
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Uriach & Cia Sa J filed Critical Uriach & Cia Sa J
Application granted granted Critical
Publication of DK0738269T3 publication Critical patent/DK0738269T3/da
Publication of DK0738269T5 publication Critical patent/DK0738269T5/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
DK95932668T 1994-11-07 1995-09-05 Piperidinderivater med PAF-antagonistaktivitet DK0738269T5 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ES09402291A ES2087038B1 (es) 1994-11-07 1994-11-07 Nuevas piperidinas con actividad antagonista del paf.
PCT/EP1995/003487 WO1996014317A1 (en) 1994-11-07 1995-09-05 Novel piperidine derivatives with paf antagonist activity

Publications (2)

Publication Number Publication Date
DK0738269T3 DK0738269T3 (da) 2000-08-28
DK0738269T5 true DK0738269T5 (da) 2000-12-18

Family

ID=8287905

Family Applications (1)

Application Number Title Priority Date Filing Date
DK95932668T DK0738269T5 (da) 1994-11-07 1995-09-05 Piperidinderivater med PAF-antagonistaktivitet

Country Status (13)

Country Link
US (1) US5705504A (da)
EP (1) EP0738269B1 (da)
JP (1) JP4018137B2 (da)
KR (1) KR100514201B1 (da)
AT (1) ATE192152T1 (da)
AU (1) AU3563695A (da)
DE (1) DE69516503T2 (da)
DK (1) DK0738269T5 (da)
ES (2) ES2087038B1 (da)
GR (1) GR3033528T3 (da)
NO (1) NO306345B1 (da)
PT (1) PT738269E (da)
WO (1) WO1996014317A1 (da)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997009329A1 (en) * 1995-09-08 1997-03-13 J. Uriach & Cia. S.A. Azo derivatives of 5-aminosalicylic acid for treatment of inflammatory bowel disease
ES2165803B1 (es) * 2000-04-10 2003-09-16 Uriach & Cia Sa J Nueva sal de un derivado azo del acido 5-aminosalicilico
GB0013060D0 (en) * 2000-05-31 2000-07-19 Astrazeneca Ab Chemical compounds
US6638950B2 (en) 2000-06-21 2003-10-28 Bristol-Myers Squibb Pharma Company Piperidine amides as modulators of chemokine receptor activity
CN100553636C (zh) 2000-08-04 2009-10-28 Dmi生物科学公司 二酮基哌嗪和包含它们的组合物的使用方法
GB0021670D0 (en) 2000-09-04 2000-10-18 Astrazeneca Ab Chemical compounds
GB0117899D0 (en) 2001-07-23 2001-09-12 Astrazeneca Ab Chemical compounds
CN103191409A (zh) 2003-05-15 2013-07-10 Dmi生物科学公司 T-细胞介导的疾病的治疗
FR2860514A1 (fr) * 2003-10-03 2005-04-08 Sanofi Synthelabo Derives d'arylalkylcarbamates, leur preparation et leur application en therapeutique
WO2007101270A1 (en) * 2006-03-02 2007-09-07 Incyte Corporation MODULATORS OF 11-β HYDROXYL STEROID DEHYDROGENASE TYPE 1, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS OF USING THE SAME
WO2008012524A1 (en) * 2006-07-24 2008-01-31 Ucb Pharma S.A. Substituted aniline derivatives
KR100737397B1 (ko) 2007-01-31 2007-07-09 한국교세라정공(주) 밀링 커터
US8217047B2 (en) 2008-05-27 2012-07-10 Dmi Acquisition Corp. Therapeutic methods and compounds
FR2962649A1 (fr) 2010-07-19 2012-01-20 Conservatoire Nat Arts Et Metiers Traitement d'une pathologie liee a un effet excessif du tnf par un compose de benzene sulfonamide
GB201101517D0 (en) * 2011-01-28 2011-03-16 Proximagen Ltd Receptor antagonists
JP2014530063A (ja) 2011-10-10 2014-11-17 アンピオ ファーマシューティカルズ，インコーポレイテッド 免疫寛容が高められた埋込み型医療用デバイス、ならびに製造方法および埋込み方法
PL2766029T3 (pl) 2011-10-10 2020-08-24 Ampio Pharmaceuticals, Inc. Leczenie choroby zwyrodnieniowej stawów
KR20140095479A (ko) 2011-10-28 2014-08-01 앰피오 파마슈티컬스 인코퍼레이티드 비염의 치료
US9808454B2 (en) 2013-03-15 2017-11-07 Ampio Pharmaceuticals, Inc. Compositions for the mobilization, homing, expansion and differentiation of stem cells and methods of using the same
AU2015305611B2 (en) 2014-08-18 2020-04-23 Ampio Pharmaceuticals, Inc. Treatment of joint conditions
US11389512B2 (en) 2015-06-22 2022-07-19 Ampio Pharmaceuticals, Inc. Use of low molecular weight fractions of human serum albumin in treating diseases

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3066434D1 (en) * 1979-11-21 1984-03-08 Kyowa Hakko Kogyo Kk Novel piperidine derivatives, method for the preparation thereof and pharmaceutical compositions containing them
IL85700A0 (en) * 1987-03-24 1988-08-31 Takeda Chemical Industries Ltd 1,4-disubstituted piperazine compounds,their production and use
EP0441226A1 (en) * 1990-01-29 1991-08-14 J. URIACH & CIA. S.A. (cyanomethyl)pyridines useful as PAF antagonists
GB9102997D0 (en) * 1991-02-13 1991-03-27 Pfizer Ltd Therapeutic agents
ES2036926B1 (es) * 1991-08-08 1994-01-16 Uriach & Cia Sa J "procedimiento para la obtencion de derivados de la (2-alquil-3-piridil)metilpiperazina".
US5268376A (en) * 1991-09-04 1993-12-07 Minnesota Mining And Manufacturing Company 1-substituted 1H-imidazo[4,5-c]quinolin-4-amines
US5283242A (en) * 1991-10-24 1994-02-01 American Home Products Corporation Substituted benzimidazoles and quinazolines as antihypertensives

Also Published As

Publication number Publication date
US5705504A (en) 1998-01-06
ES2087038A1 (es) 1996-07-01
ES2147616T3 (es) 2000-09-16
MX9602559A (es) 1997-07-31
NO962855D0 (no) 1996-07-05
NO962855L (no) 1996-07-05
JP4018137B2 (ja) 2007-12-05
PT738269E (pt) 2000-08-31
NO306345B1 (no) 1999-10-25
JPH09507862A (ja) 1997-08-12
EP0738269A1 (en) 1996-10-23
ES2087038B1 (es) 1997-03-16
DK0738269T3 (da) 2000-08-28
GR3033528T3 (en) 2000-09-29
EP0738269B1 (en) 2000-04-26
AU3563695A (en) 1996-05-31
KR100514201B1 (ko) 2005-12-29
ATE192152T1 (de) 2000-05-15
WO1996014317A1 (en) 1996-05-17
DE69516503T2 (de) 2001-03-15
DE69516503D1 (de) 2000-05-31

Similar Documents

Publication Publication Date Title
DK0738269T3 (da) Piperidinderivater med PAF-antagonistaktivitet
TR199900255T2 (xx) Muskarinik antagonistleri
NO306346B1 (no) N-substituerte azabicykloalkanderivater, anvendelse derav og farmasöytisk preparat
AU4437896A (en) Piperidine derivatives having tachykinin antagonist activity
DE69512930T2 (de) Stilben-derivate verwendbar als cyclooxygenase-2 hemmer
ES2164657T3 (es) Derivados aza-biciclicos puenteados como antagonistas de la sustancia p.
DE69422303T2 (de) Neue 4-piperidinyl substituierte lactame als neukokinin 2 rezeptor antagonisten zur behandlung von asthma
ATE175114T1 (de) Pharmazeutische zusammensetzungen enthaltend einen opiat antagonist und calcium salze, ihre verwendung zur behandlung von endorphin- vermittelten krankheiten
ATE224884T1 (de) Muscarin-antagonisten
DK0783501T3 (da) Pyrimidonderivater med anti-fungal aktivitet
ATE183496T1 (de) Amidderivate und ihre therapeutische verwendung
NO306400B1 (no) N-substituerte azabicykloheptan-derivater, anvendelse derav og farmasöytisk preparat
GR3032950T3 (en) Substituted fused and bridged bicyclic compounds as therapeutic agents
EA200100361A1 (ru) Сложные эфиры (+)-альфа-(2,3-диметоксифенил)-1-[2-(4-фторфенил)этил]-4-пиперидинметанола и их использование в качестве пролекарств антагониста mdl 110907 5htрецепторов
CA2180660A1 (en) Novel piperidine derivatives with paf antagonist activity
EE03488B1 (et) Meetod anhüdroekgoniini estrite valmistamiseks