DE69516503D1 - Piperidinderivate mit paf antagonistischer wirkung - Google Patents

Piperidinderivate mit paf antagonistischer wirkung

Info

Publication number
DE69516503D1
DE69516503D1 DE69516503T DE69516503T DE69516503D1 DE 69516503 D1 DE69516503 D1 DE 69516503D1 DE 69516503 T DE69516503 T DE 69516503T DE 69516503 T DE69516503 T DE 69516503T DE 69516503 D1 DE69516503 D1 DE 69516503D1
Authority
DE
Germany
Prior art keywords
pct
antagonistic effect
paf
paf antagonistic
piperide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69516503T
Other languages
English (en)
Other versions
DE69516503T2 (de
Inventor
Elena Carceller
J Jimenez
Nuria Recasens
Jordi Salas
Carmen Almansa
Javier Bartroli
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Palau Pharma SA
Original Assignee
J Uriach y Cia SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by J Uriach y Cia SA filed Critical J Uriach y Cia SA
Application granted granted Critical
Publication of DE69516503D1 publication Critical patent/DE69516503D1/de
Publication of DE69516503T2 publication Critical patent/DE69516503T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
DE69516503T 1994-11-07 1995-09-05 Piperidinderivate mit paf antagonistischer wirkung Expired - Lifetime DE69516503T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ES09402291A ES2087038B1 (es) 1994-11-07 1994-11-07 Nuevas piperidinas con actividad antagonista del paf.
PCT/EP1995/003487 WO1996014317A1 (en) 1994-11-07 1995-09-05 Novel piperidine derivatives with paf antagonist activity

Publications (2)

Publication Number Publication Date
DE69516503D1 true DE69516503D1 (de) 2000-05-31
DE69516503T2 DE69516503T2 (de) 2001-03-15

Family

ID=8287905

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69516503T Expired - Lifetime DE69516503T2 (de) 1994-11-07 1995-09-05 Piperidinderivate mit paf antagonistischer wirkung

Country Status (13)

Country Link
US (1) US5705504A (de)
EP (1) EP0738269B1 (de)
JP (1) JP4018137B2 (de)
KR (1) KR100514201B1 (de)
AT (1) ATE192152T1 (de)
AU (1) AU3563695A (de)
DE (1) DE69516503T2 (de)
DK (1) DK0738269T5 (de)
ES (2) ES2087038B1 (de)
GR (1) GR3033528T3 (de)
NO (1) NO306345B1 (de)
PT (1) PT738269E (de)
WO (1) WO1996014317A1 (de)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69611598T2 (de) * 1995-09-08 2001-06-07 Uriach & Cia Sa J Azoderivate von 5-aminosalicylsäure zur behandlung von enzündlichen darmerkrankungen
ES2165803B1 (es) * 2000-04-10 2003-09-16 Uriach & Cia Sa J Nueva sal de un derivado azo del acido 5-aminosalicilico
GB0013060D0 (en) 2000-05-31 2000-07-19 Astrazeneca Ab Chemical compounds
US6638950B2 (en) 2000-06-21 2003-10-28 Bristol-Myers Squibb Pharma Company Piperidine amides as modulators of chemokine receptor activity
CA2774959C (en) * 2000-08-04 2016-05-31 Dmi Biosciences, Inc. Method of using diketopiperazines and composition containing them
GB0021670D0 (en) 2000-09-04 2000-10-18 Astrazeneca Ab Chemical compounds
GB0117899D0 (en) 2001-07-23 2001-09-12 Astrazeneca Ab Chemical compounds
JP2007500747A (ja) 2003-05-15 2007-01-18 ディーエムアイ バイオサイエンシズ インコーポレイテッド Ｔ細胞媒介性疾患の処置
FR2860514A1 (fr) * 2003-10-03 2005-04-08 Sanofi Synthelabo Derives d'arylalkylcarbamates, leur preparation et leur application en therapeutique
WO2007101270A1 (en) * 2006-03-02 2007-09-07 Incyte Corporation MODULATORS OF 11-β HYDROXYL STEROID DEHYDROGENASE TYPE 1, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS OF USING THE SAME
CA2658913C (en) * 2006-07-24 2015-07-21 Ucb Pharma S.A. Substituted aniline derivatives
KR100737397B1 (ko) 2007-01-31 2007-07-09 한국교세라정공(주) 밀링 커터
JP5856843B2 (ja) 2008-05-27 2016-02-10 アンピオ ファーマシューティカルズ，インコーポレイテッド ジケトピペラジンを用いた医薬組成物
FR2962649A1 (fr) 2010-07-19 2012-01-20 Conservatoire Nat Arts Et Metiers Traitement d'une pathologie liee a un effet excessif du tnf par un compose de benzene sulfonamide
GB201101517D0 (en) * 2011-01-28 2011-03-16 Proximagen Ltd Receptor antagonists
SG10201608087WA (en) 2011-10-10 2016-11-29 Ampio Pharmaceuticals Inc Implantable medical devices with increased immune tolerance, and methods for making and implanting
EP2766029B1 (de) 2011-10-10 2020-03-25 Ampio Pharmaceuticals, Inc. Behandlung degenerativer gelenkerkrankungen
MX355446B (es) 2011-10-28 2018-04-18 Ampio Pharmaceuticals Inc Tratamiento de rinitis.
CA2906864A1 (en) 2013-03-15 2014-09-18 Ampio Pharmaceuticals, Inc. Compositions for the mobilization, homing, expansion and differentiation of stem cells and methods of using the same
KR20170045274A (ko) 2014-08-18 2017-04-26 앰피오 파마슈티컬스 인코퍼레이티드 관절 징후의 치료
US11389512B2 (en) 2015-06-22 2022-07-19 Ampio Pharmaceuticals, Inc. Use of low molecular weight fractions of human serum albumin in treating diseases

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0029707B1 (de) * 1979-11-21 1984-02-01 Kyowa Hakko Kogyo Co., Ltd Piperidinderivate, Verfahren zu ihrer Herstellung und sie enthaltende pharmazeutische Zusammensetzungen
IL85700A0 (en) * 1987-03-24 1988-08-31 Takeda Chemical Industries Ltd 1,4-disubstituted piperazine compounds,their production and use
EP0441226A1 (de) * 1990-01-29 1991-08-14 J. URIACH & CIA. S.A. (Cyanomethyl)-Pyridine verwendbar als PAF Antagonisten
GB9102997D0 (en) * 1991-02-13 1991-03-27 Pfizer Ltd Therapeutic agents
ES2036926B1 (es) * 1991-08-08 1994-01-16 Uriach & Cia Sa J "procedimiento para la obtencion de derivados de la (2-alquil-3-piridil)metilpiperazina".
US5268376A (en) * 1991-09-04 1993-12-07 Minnesota Mining And Manufacturing Company 1-substituted 1H-imidazo[4,5-c]quinolin-4-amines
US5283242A (en) * 1991-10-24 1994-02-01 American Home Products Corporation Substituted benzimidazoles and quinazolines as antihypertensives

Also Published As

Publication number Publication date
PT738269E (pt) 2000-08-31
ES2147616T3 (es) 2000-09-16
MX9602559A (es) 1997-07-31
DE69516503T2 (de) 2001-03-15
ATE192152T1 (de) 2000-05-15
AU3563695A (en) 1996-05-31
NO962855L (no) 1996-07-05
NO962855D0 (no) 1996-07-05
GR3033528T3 (en) 2000-09-29
DK0738269T3 (da) 2000-08-28
JPH09507862A (ja) 1997-08-12
EP0738269A1 (de) 1996-10-23
DK0738269T5 (da) 2000-12-18
NO306345B1 (no) 1999-10-25
WO1996014317A1 (en) 1996-05-17
ES2087038A1 (es) 1996-07-01
EP0738269B1 (de) 2000-04-26
JP4018137B2 (ja) 2007-12-05
US5705504A (en) 1998-01-06
ES2087038B1 (es) 1997-03-16
KR100514201B1 (ko) 2005-12-29

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Legal Events

Date Code Title Description
8332 No legal effect for de
8370 Indication related to discontinuation of the patent is to be deleted
8364 No opposition during term of opposition
8328 Change in the person/name/address of the agent

Representative=s name: PFENNING MEINIG & PARTNER GBR, 80339 MUENCHEN

8327 Change in the person/name/address of the patent owner

Owner name: PALAU PHARMA,S.A., PALAU-SOLITA I PLEGAMANS, B, ES

8328 Change in the person/name/address of the agent

Representative=s name: MAIWALD PATENTANWALTSGESELLSCHAFT MBH, 80335 MUENC