DK0569795T3 - Sulfonylbenzyl-substituerede benzo- og pyridopyridoner - Google Patents

Sulfonylbenzyl-substituerede benzo- og pyridopyridoner

Info

Publication number
DK0569795T3
DK0569795T3 DK93106988.4T DK93106988T DK0569795T3 DK 0569795 T3 DK0569795 T3 DK 0569795T3 DK 93106988 T DK93106988 T DK 93106988T DK 0569795 T3 DK0569795 T3 DK 0569795T3
Authority
DK
Denmark
Prior art keywords
pyridopyridones
substituted benzo
sulfonylbenzyl
sulphonylbenzyl
benzo
Prior art date
Application number
DK93106988.4T
Other languages
English (en)
Inventor
Ulrich E Dr Mueller
Peter Dr Fey
Andreas Dr Knorr
Martin Dr Beuck
Walter Dr Huebsch
Thomas Dr Kraemer
Stanislav Prof Dr Kazda
Stefan Dr Wohlfeil
Matthias Dr Mueller-Gliemann
Juergen Dr Dressel
Rudolf H Dr Hanko
Johannes-Peter Dr Stasch
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Application granted granted Critical
Publication of DK0569795T3 publication Critical patent/DK0569795T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
    • C07D217/24—Oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Pyridine Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK93106988.4T 1992-05-12 1993-04-29 Sulfonylbenzyl-substituerede benzo- og pyridopyridoner DK0569795T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4215587A DE4215587A1 (de) 1992-05-12 1992-05-12 Sulfonylbenzyl-substituierte Benzo- und Pyridopyridone

Publications (1)

Publication Number Publication Date
DK0569795T3 true DK0569795T3 (da) 1995-08-28

Family

ID=6458654

Family Applications (1)

Application Number Title Priority Date Filing Date
DK93106988.4T DK0569795T3 (da) 1992-05-12 1993-04-29 Sulfonylbenzyl-substituerede benzo- og pyridopyridoner

Country Status (21)

Country Link
US (1) US5354749A (da)
EP (1) EP0569795B1 (da)
JP (1) JPH0649031A (da)
KR (1) KR930023362A (da)
CN (1) CN1080923A (da)
AT (1) ATE121086T1 (da)
AU (1) AU3710693A (da)
CA (1) CA2095801A1 (da)
CZ (1) CZ72393A3 (da)
DE (2) DE4215587A1 (da)
DK (1) DK0569795T3 (da)
ES (1) ES2072784T3 (da)
FI (1) FI932105A (da)
GR (1) GR3015836T3 (da)
HU (1) HU9301366D0 (da)
IL (1) IL105646A0 (da)
MX (1) MX9302461A (da)
NO (1) NO931534L (da)
PL (1) PL298890A1 (da)
SK (1) SK46693A3 (da)
ZA (1) ZA933273B (da)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4301900A1 (de) * 1993-01-25 1994-07-28 Bayer Ag 2-Oxochinolin-1-yl-methylphenylessigsäurederivate
TW263498B (da) * 1993-11-10 1995-11-21 Takeda Pharm Industry Co Ltd
CA2584485C (en) * 2004-10-20 2013-12-31 Resverlogix Corp. Stilbenes and chalcones for the prevention and treatment of cardiovascular diseases
WO2007016525A2 (en) 2005-07-29 2007-02-08 Resverlogix Corp. Pharmaceutical compositions for the prevention and treatment of complex diseases and their delivery by insertable medical devices
DK2118074T3 (da) * 2007-02-01 2014-03-10 Resverlogix Corp Forbindelser til forebyggelse og behandling af hjertekarsygdomme
ES2532402T3 (es) 2008-06-26 2015-03-26 Resverlogix Corporation Métodos de preparación de derivados de quinazolinona
US8153808B2 (en) 2008-12-23 2012-04-10 Roche Palo Alto Llc Dihydropyridone amides as P2X7 modulators
WO2010072605A1 (en) 2008-12-23 2010-07-01 F. Hoffmann-La Roche Ag Dihydropyridone amides as p2x7 modulators
MX2011006843A (es) 2008-12-23 2011-08-04 Hoffmann La Roche Dihidropiridona-amidas como moduladores de p2x7.
EP2385939A1 (en) 2008-12-23 2011-11-16 F. Hoffmann-La Roche AG Dihydropyridone amides as p2x7 modulators
JP2012513435A (ja) 2008-12-23 2012-06-14 エフ．ホフマン−ラ ロシュ アーゲー Ｐ２ｘ７調節薬としてのジヒドロピリドンアミド
NZ594332A (en) 2009-01-08 2013-09-27 Resverlogix Corp Compounds for the prevention and treatment of cardiovascular disease
NZ755378A (en) 2009-03-18 2022-07-29 Resverlogix Corp Novel quinazolinones and related compounds for use as anti-inflammatory agents
US9757368B2 (en) 2009-04-22 2017-09-12 Resverlogix Corp. Anti-inflammatory agents
PT2773354T (pt) 2011-11-01 2019-07-17 Resverlogix Corp Formulações orais de libertação imediata para quinazolinonas substituídas
US9765039B2 (en) 2012-11-21 2017-09-19 Zenith Epigenetics Ltd. Biaryl derivatives as bromodomain inhibitors
US9073878B2 (en) 2012-11-21 2015-07-07 Zenith Epigenetics Corp. Cyclic amines as bromodomain inhibitors
CA2895905A1 (en) 2012-12-21 2014-06-26 Zenith Epigenetics Corp. Novel heterocyclic compounds as bromodomain inhibitors
CA2977308A1 (en) 2015-03-13 2016-09-22 Resverlogix Corp. Compositions and therapeutic methods for the treatment of complement-associated diseases
CN110327347B (zh) * 2019-08-16 2021-06-01 陕西科技大学 G-749在制备抗真菌药物中的应用

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2314985A1 (de) * 1973-03-26 1974-10-17 Hoechst Ag 1-(imidazol-1-yl)-isochinoline und verfahren zu ihrer herstellung
JPS6145820A (ja) * 1984-03-07 1986-03-05 Nippon Piston Ring Co Ltd 粉末成形体の定間隔整列方法及びその整列装置
DE3800785A1 (de) * 1988-01-09 1989-07-20 Hoechst Ag Substituierte 7-(pyridazin-5-yl)-3,5-dihydroxyheptan(en)- saeuren, ihre entsprechenden (delta)-lactone bzw. derivate, verfahren zu ihrer herstellung, ihre verwendung als arzneimittel, pharmazeutische praeparate und zwischenprodukte
IE64514B1 (en) * 1989-05-23 1995-08-09 Zeneca Ltd Azaindenes
GB8911854D0 (en) * 1989-05-23 1989-07-12 Ici Plc Heterocyclic compounds
CA2018443A1 (en) * 1989-06-14 1990-12-14 Joseph A. Finkelstein Imidazolyl-alkenoic acids
DE69034103T2 (de) * 1989-06-14 2004-07-15 Smithkline Beecham Corp. Imidazoalkensäure
US5164407A (en) * 1989-07-03 1992-11-17 Merck & Co., Inc. Substituted imidazo-fused 5-membered ring heterocycles and their use as angiotensin ii antagonsists
EP0485410A1 (en) * 1989-07-06 1992-05-20 The Secretary Of State For Defence In Her Britannic Majesty's Government Of The United Kingdom Of Great Britain And Northern A detector for monitoring low molecular weight compounds
EP0412848B1 (en) * 1989-08-11 1995-01-18 Zeneca Limited Quinoline derivatives, process for their preparation and their use as medicaments
CA2027937A1 (en) * 1989-10-25 1991-04-26 Richard M. Keenan Substituted 5-¬ (tetrazolyl)alkenyl|imidazoles
JP2860676B2 (ja) * 1989-12-07 1999-02-24 川研ファインケミカル株式会社 １―イソキノリン類の製造方法
GB9010394D0 (en) * 1990-05-09 1990-06-27 Ici Plc Heterocyclic compounds
IL99246A0 (en) * 1990-09-10 1992-07-15 Abbott Lab Angiotensin ii receptor antagonists and pharmaceutical compositions containing them
GB9025123D0 (en) * 1990-11-19 1991-01-02 Ici Plc Nitrogen compounds
US5162325A (en) * 1991-05-07 1992-11-10 Merck & Co., Inc. Angiotensin ii antagonists incorporating a substituted benzyl element
US5162340A (en) * 1991-05-10 1992-11-10 Merck & Co., Inc. Substituted 1-(2h)-isoquinolinones bearing acidic functional groups as angiotensin ii antagonists
US5256667A (en) * 1991-09-25 1993-10-26 Merck & Co., Inc. Quinazolinones and pyridopyrimidinones
DE4206045A1 (de) * 1992-02-27 1993-09-02 Bayer Ag Sulfonylbenzyl substituierte pyridone

Also Published As

Publication number Publication date
ES2072784T3 (es) 1995-07-16
US5354749A (en) 1994-10-11
AU3710693A (en) 1993-11-18
KR930023362A (ko) 1993-12-18
HU9301366D0 (en) 1993-09-28
DE59300135D1 (de) 1995-05-18
NO931534L (no) 1993-11-15
JPH0649031A (ja) 1994-02-22
CA2095801A1 (en) 1993-11-13
PL298890A1 (en) 1994-01-10
IL105646A0 (en) 1993-09-22
ZA933273B (en) 1993-11-29
MX9302461A (es) 1994-06-30
ATE121086T1 (de) 1995-04-15
CZ72393A3 (en) 1993-12-15
EP0569795A1 (de) 1993-11-18
GR3015836T3 (en) 1995-07-31
EP0569795B1 (de) 1995-04-12
FI932105A0 (fi) 1993-05-10
FI932105A (fi) 1993-11-13
DE4215587A1 (de) 1993-11-18
CN1080923A (zh) 1994-01-19
SK46693A3 (en) 1994-02-02
NO931534D0 (no) 1993-04-27

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