IL105646A0 - Sulfonylbenzyl-substituted benzo-and pyridopyridones,their preparation and pharmaceutical compositions containing them - Google Patents
Sulfonylbenzyl-substituted benzo-and pyridopyridones,their preparation and pharmaceutical compositions containing themInfo
- Publication number
- IL105646A0 IL105646A0 IL105646A IL10564693A IL105646A0 IL 105646 A0 IL105646 A0 IL 105646A0 IL 105646 A IL105646 A IL 105646A IL 10564693 A IL10564693 A IL 10564693A IL 105646 A0 IL105646 A0 IL 105646A0
- Authority
- IL
- Israel
- Prior art keywords
- pyridopyridones
- substituted benzo
- sulfonylbenzyl
- preparation
- pharmaceutical compositions
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
- C07D217/24—Oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Pyridine Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE4215587A DE4215587A1 (de) | 1992-05-12 | 1992-05-12 | Sulfonylbenzyl-substituierte Benzo- und Pyridopyridone |
Publications (1)
Publication Number | Publication Date |
---|---|
IL105646A0 true IL105646A0 (en) | 1993-09-22 |
Family
ID=6458654
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL105646A IL105646A0 (en) | 1992-05-12 | 1993-05-10 | Sulfonylbenzyl-substituted benzo-and pyridopyridones,their preparation and pharmaceutical compositions containing them |
Country Status (21)
Country | Link |
---|---|
US (1) | US5354749A (xx) |
EP (1) | EP0569795B1 (xx) |
JP (1) | JPH0649031A (xx) |
KR (1) | KR930023362A (xx) |
CN (1) | CN1080923A (xx) |
AT (1) | ATE121086T1 (xx) |
AU (1) | AU3710693A (xx) |
CA (1) | CA2095801A1 (xx) |
CZ (1) | CZ72393A3 (xx) |
DE (2) | DE4215587A1 (xx) |
DK (1) | DK0569795T3 (xx) |
ES (1) | ES2072784T3 (xx) |
FI (1) | FI932105A (xx) |
GR (1) | GR3015836T3 (xx) |
HU (1) | HU9301366D0 (xx) |
IL (1) | IL105646A0 (xx) |
MX (1) | MX9302461A (xx) |
NO (1) | NO931534L (xx) |
PL (1) | PL298890A1 (xx) |
SK (1) | SK46693A3 (xx) |
ZA (1) | ZA933273B (xx) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE4301900A1 (de) * | 1993-01-25 | 1994-07-28 | Bayer Ag | 2-Oxochinolin-1-yl-methylphenylessigsäurederivate |
TW263498B (xx) * | 1993-11-10 | 1995-11-21 | Takeda Pharm Industry Co Ltd | |
CA2584507C (en) * | 2004-10-20 | 2016-04-26 | Resverlogix Corp. | Flavanoids and isoflavanoids for the prevention and treatment of cardiovascular diseases |
US8410109B2 (en) | 2005-07-29 | 2013-04-02 | Resverlogix Corp. | Pharmaceutical compositions for the prevention and treatment of complex diseases and their delivery by insertable medical devices |
WO2008092231A1 (en) | 2007-02-01 | 2008-08-07 | Resverlogix Corp. | Compounds for the prevention and treatment of cardiovascular diseases |
AU2009262252B2 (en) | 2008-06-26 | 2013-05-02 | Resverlogix Corp. | Methods of preparing quinazolinone derivatives |
WO2010072607A1 (en) | 2008-12-23 | 2010-07-01 | F. Hoffmann-La Roche Ag | Dihydropyridone amides as p2x7 modulators |
CA2745866A1 (en) | 2008-12-23 | 2010-07-01 | F.Hoffmann-La Roche Ag | Dihydropyridone ureas as p2x7 modulators |
SG172336A1 (en) | 2008-12-23 | 2011-07-28 | Hoffmann La Roche | Dihydropyridone amides as p2x7 modulators |
SG172785A1 (en) | 2008-12-23 | 2011-08-29 | Hoffmann La Roche | Dihydropyridone amides as p2x7 modulators |
US8153808B2 (en) | 2008-12-23 | 2012-04-10 | Roche Palo Alto Llc | Dihydropyridone amides as P2X7 modulators |
ES2463097T3 (es) | 2009-01-08 | 2014-05-27 | Resverlogix Corp. | Compuestos para la prevención y el tratamiento de enfermedades cardiovasculares |
JP5795304B2 (ja) | 2009-03-18 | 2015-10-14 | レスバーロジックス コーポレイション | 新規抗炎症剤 |
KR102215167B1 (ko) | 2009-04-22 | 2021-02-16 | 리스버로직스 코퍼레이션 | 신규한 소염제 |
PT2773354T (pt) | 2011-11-01 | 2019-07-17 | Resverlogix Corp | Formulações orais de libertação imediata para quinazolinonas substituídas |
US9765039B2 (en) | 2012-11-21 | 2017-09-19 | Zenith Epigenetics Ltd. | Biaryl derivatives as bromodomain inhibitors |
WO2014080290A2 (en) | 2012-11-21 | 2014-05-30 | Rvx Therapeutics Inc. | Cyclic amines as bromodomain inhibitors |
WO2014096965A2 (en) | 2012-12-21 | 2014-06-26 | Rvx Therapeutics Inc. | Novel heterocyclic compounds as bromodomain inhibitors |
EP3268007B1 (en) | 2015-03-13 | 2022-11-09 | Resverlogix Corp. | Compositions and therapeutic methods for the treatment of complement-associated diseases |
CN110327347B (zh) * | 2019-08-16 | 2021-06-01 | 陕西科技大学 | G-749在制备抗真菌药物中的应用 |
Family Cites Families (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2314985A1 (de) * | 1973-03-26 | 1974-10-17 | Hoechst Ag | 1-(imidazol-1-yl)-isochinoline und verfahren zu ihrer herstellung |
JPS6145820A (ja) * | 1984-03-07 | 1986-03-05 | Nippon Piston Ring Co Ltd | 粉末成形体の定間隔整列方法及びその整列装置 |
DE3800785A1 (de) * | 1988-01-09 | 1989-07-20 | Hoechst Ag | Substituierte 7-(pyridazin-5-yl)-3,5-dihydroxyheptan(en)- saeuren, ihre entsprechenden (delta)-lactone bzw. derivate, verfahren zu ihrer herstellung, ihre verwendung als arzneimittel, pharmazeutische praeparate und zwischenprodukte |
GB8911854D0 (en) * | 1989-05-23 | 1989-07-12 | Ici Plc | Heterocyclic compounds |
IE64514B1 (en) * | 1989-05-23 | 1995-08-09 | Zeneca Ltd | Azaindenes |
CA2018443A1 (en) * | 1989-06-14 | 1990-12-14 | Joseph A. Finkelstein | Imidazolyl-alkenoic acids |
EP0955294B1 (en) * | 1989-06-14 | 2003-09-24 | Smithkline Beecham Corporation | Imidazolyl-alkenoic acid |
US5164407A (en) * | 1989-07-03 | 1992-11-17 | Merck & Co., Inc. | Substituted imidazo-fused 5-membered ring heterocycles and their use as angiotensin ii antagonsists |
WO1991001001A1 (en) * | 1989-07-06 | 1991-01-24 | The Secretary Of State For Defence In Her Britannic Majesty's Government Of The United Kingdom Of Great Britain And Northern Ireland | A detector for monitoring low molecular weight compounds |
PL286445A1 (en) * | 1989-08-11 | 1991-04-22 | Ici Plc | Method of obtaining novel quinoline derivatives |
CA2027937A1 (en) * | 1989-10-25 | 1991-04-26 | Richard M. Keenan | Substituted 5-¬ (tetrazolyl)alkenyl|imidazoles |
JP2860676B2 (ja) * | 1989-12-07 | 1999-02-24 | 川研ファインケミカル株式会社 | 1―イソキノリン類の製造方法 |
GB9010394D0 (en) * | 1990-05-09 | 1990-06-27 | Ici Plc | Heterocyclic compounds |
IE912956A1 (en) * | 1990-09-10 | 1992-03-11 | Abbott Lab | Angiotensin ii receptor antagonists |
GB9025123D0 (en) * | 1990-11-19 | 1991-01-02 | Ici Plc | Nitrogen compounds |
US5162325A (en) * | 1991-05-07 | 1992-11-10 | Merck & Co., Inc. | Angiotensin ii antagonists incorporating a substituted benzyl element |
US5162340A (en) * | 1991-05-10 | 1992-11-10 | Merck & Co., Inc. | Substituted 1-(2h)-isoquinolinones bearing acidic functional groups as angiotensin ii antagonists |
US5256667A (en) * | 1991-09-25 | 1993-10-26 | Merck & Co., Inc. | Quinazolinones and pyridopyrimidinones |
DE4206045A1 (de) * | 1992-02-27 | 1993-09-02 | Bayer Ag | Sulfonylbenzyl substituierte pyridone |
-
1992
- 1992-05-12 DE DE4215587A patent/DE4215587A1/de not_active Withdrawn
-
1993
- 1993-04-22 AU AU37106/93A patent/AU3710693A/en not_active Abandoned
- 1993-04-23 CZ CZ93723A patent/CZ72393A3/cs unknown
- 1993-04-27 NO NO93931534A patent/NO931534L/no unknown
- 1993-04-27 MX MX9302461A patent/MX9302461A/es unknown
- 1993-04-29 ES ES93106988T patent/ES2072784T3/es not_active Expired - Lifetime
- 1993-04-29 EP EP93106988A patent/EP0569795B1/de not_active Expired - Lifetime
- 1993-04-29 DK DK93106988.4T patent/DK0569795T3/da active
- 1993-04-29 DE DE59300135T patent/DE59300135D1/de not_active Expired - Fee Related
- 1993-04-29 AT AT93106988T patent/ATE121086T1/de active
- 1993-05-05 US US08/058,548 patent/US5354749A/en not_active Expired - Fee Related
- 1993-05-06 JP JP5127805A patent/JPH0649031A/ja active Pending
- 1993-05-07 CA CA002095801A patent/CA2095801A1/en not_active Abandoned
- 1993-05-10 IL IL105646A patent/IL105646A0/xx unknown
- 1993-05-10 FI FI932105A patent/FI932105A/fi not_active Application Discontinuation
- 1993-05-10 PL PL29889093A patent/PL298890A1/xx unknown
- 1993-05-11 ZA ZA933273A patent/ZA933273B/xx unknown
- 1993-05-11 HU HU9301366A patent/HU9301366D0/hu unknown
- 1993-05-11 KR KR1019930008039A patent/KR930023362A/ko not_active Application Discontinuation
- 1993-05-12 SK SK466-93A patent/SK46693A3/sk unknown
- 1993-05-12 CN CN93105760A patent/CN1080923A/zh active Pending
-
1995
- 1995-04-17 GR GR950400966T patent/GR3015836T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
HU9301366D0 (en) | 1993-09-28 |
KR930023362A (ko) | 1993-12-18 |
GR3015836T3 (en) | 1995-07-31 |
DE59300135D1 (de) | 1995-05-18 |
EP0569795B1 (de) | 1995-04-12 |
NO931534L (no) | 1993-11-15 |
ES2072784T3 (es) | 1995-07-16 |
CN1080923A (zh) | 1994-01-19 |
US5354749A (en) | 1994-10-11 |
DK0569795T3 (da) | 1995-08-28 |
DE4215587A1 (de) | 1993-11-18 |
FI932105A (fi) | 1993-11-13 |
MX9302461A (es) | 1994-06-30 |
FI932105A0 (fi) | 1993-05-10 |
NO931534D0 (no) | 1993-04-27 |
SK46693A3 (en) | 1994-02-02 |
ZA933273B (en) | 1993-11-29 |
AU3710693A (en) | 1993-11-18 |
CZ72393A3 (en) | 1993-12-15 |
EP0569795A1 (de) | 1993-11-18 |
CA2095801A1 (en) | 1993-11-13 |
JPH0649031A (ja) | 1994-02-22 |
PL298890A1 (en) | 1994-01-10 |
ATE121086T1 (de) | 1995-04-15 |
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