DK0534343T3 - Substituerede pyridinylamino-1H-indoler, 1H-indazoler, 2H-indazoler, benzo[b]thiophener og 1,2-benzoisothiazoler, fremgangs - Google Patents

Substituerede pyridinylamino-1H-indoler, 1H-indazoler, 2H-indazoler, benzo[b]thiophener og 1,2-benzoisothiazoler, fremgangs

Info

Publication number
DK0534343T3
DK0534343T3 DK92116110T DK92116110T DK0534343T3 DK 0534343 T3 DK0534343 T3 DK 0534343T3 DK 92116110 T DK92116110 T DK 92116110T DK 92116110 T DK92116110 T DK 92116110T DK 0534343 T3 DK0534343 T3 DK 0534343T3
Authority
DK
Denmark
Prior art keywords
indazoles
loweralkyl
hydrogen
compounds
useful
Prior art date
Application number
DK92116110T
Other languages
English (en)
Inventor
Richard Charles Effland
Joseph Thomas Klein
Lawrence Leo Martin
Original Assignee
Hoechst Marion Roussel Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Marion Roussel Inc filed Critical Hoechst Marion Roussel Inc
Application granted granted Critical
Publication of DK0534343T3 publication Critical patent/DK0534343T3/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, ***e
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Hospice & Palliative Care (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK92116110T 1991-09-23 1992-09-21 Substituerede pyridinylamino-1H-indoler, 1H-indazoler, 2H-indazoler, benzo[b]thiophener og 1,2-benzoisothiazoler, fremgangs DK0534343T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/764,031 US5185350A (en) 1991-09-23 1991-09-23 Substituted pyridinylamino-1h-indoles,1h-indazoles,2h-indazoles, benzo (b)thiophenes and 1,2-benzisothiazoles

Publications (1)

Publication Number Publication Date
DK0534343T3 true DK0534343T3 (da) 1998-07-27

Family

ID=25069502

Family Applications (1)

Application Number Title Priority Date Filing Date
DK92116110T DK0534343T3 (da) 1991-09-23 1992-09-21 Substituerede pyridinylamino-1H-indoler, 1H-indazoler, 2H-indazoler, benzo[b]thiophener og 1,2-benzoisothiazoler, fremgangs

Country Status (18)

Country Link
US (2) US5185350A (da)
EP (1) EP0534343B1 (da)
JP (1) JP2961023B2 (da)
KR (1) KR930006006A (da)
AT (1) ATE160346T1 (da)
AU (1) AU653263B2 (da)
CA (1) CA2078814C (da)
CZ (1) CZ290692A3 (da)
DE (1) DE69223205T2 (da)
DK (1) DK0534343T3 (da)
ES (1) ES2111025T3 (da)
FI (1) FI924230A (da)
GR (1) GR3025774T3 (da)
HU (1) HUT64055A (da)
IL (1) IL103232A0 (da)
MX (1) MX9205374A (da)
NO (1) NO923686L (da)
TW (1) TW207539B (da)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0550507A1 (en) * 1990-09-13 1993-07-14 Beecham Group p.l.c. Indole ureas as 5 ht receptor antagonist
US5356910A (en) 1993-07-19 1994-10-18 Hoechst-Roussel Pharmaceuticals Inc. Use of N-(pyridinyl)-1H-indol-1-amines for the treatment of obsessive-compulsive disorder
CA2176127A1 (en) * 1993-12-21 1995-06-29 William Henry Walker Lunn Methods for the treatment or prevention of conditions associated with amyloidogenic reptides
DE19626373A1 (de) * 1996-07-02 1998-01-08 Boehringer Ingelheim Kg Neuartige Verwendung von Wirkstoffen, welche die Funktion von nichtneuronalem Acetylcholin beeinflussen
TW200302722A (en) * 2002-02-13 2003-08-16 Astrazeneca Ab Therapeutic agents
US20050222123A1 (en) 2004-01-27 2005-10-06 North Shore-Long Island Jewish Research Institute Cholinesterase inhibitors for treating inflammation
JP4857128B2 (ja) 2004-02-20 2012-01-18 グラクソスミスクライン・リミテッド・ライアビリティ・カンパニー 新規な化合物
JP4787471B2 (ja) * 2004-05-21 2011-10-05 株式会社ポッカコーポレーション 脳機能亢進剤
AU2005250116B2 (en) 2004-06-01 2011-01-20 F. Hoffmann-La Roche Ag 3-amino-1-arylpropyl indoles as monoamine reuptake inhibitor
CA2632284A1 (en) 2005-11-30 2007-06-07 F. Hoffmann-La Roche Ag 3-amino-2-arylpropyl azaindoles and uses thereof
CN101316818B (zh) 2005-11-30 2011-08-31 弗·哈夫曼-拉罗切有限公司 3-氨基-1-芳基丙基吲哚类和氮杂取代的吲哚类
EP2351737A1 (en) * 2005-11-30 2011-08-03 F. Hoffmann-La Roche AG 3-Amino-1-arylpropyl indoles and aza-substituted indoles
KR102534969B1 (ko) * 2021-08-20 2023-05-26 김수영 포켓 인슐레이터 및 이를 포함하는 단열체

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3852335T2 (de) * 1987-04-24 1995-05-11 Hoechst Roussel Pharma N-(Pyridinyl)-1H-indol-1-amine, Verfahren zu deren Herstellung und ihre Verwendung als Arzneimittel.
US4970219A (en) * 1989-06-28 1990-11-13 Hoechst-Roussel Pharmaceuticals Inc. Heteroarylamino- and heteroaryloxypyridinamine compounds which have useful utility in treating skin disorders
US4983615A (en) * 1989-06-28 1991-01-08 Hoechst-Roussel Pharmaceuticals Inc. Heteroarylamino- and heteroaryloxypyridinamine compounds which are useful in treating skin disorders
US5006537A (en) * 1989-08-02 1991-04-09 Hoechst-Roussel Pharmaceuticals, Inc. 1,3-dihydro-1-(pyridinylamino)-2H-indol-2-ones
US5177088A (en) * 1991-04-17 1993-01-05 Hoechst-Roussel Pharmaceuticals Incorporated Substituted 3-(pyridinylamino)-indoles

Also Published As

Publication number Publication date
AU2529792A (en) 1993-03-25
EP0534343B1 (en) 1997-11-19
US5328918A (en) 1994-07-12
CA2078814C (en) 2003-09-09
MX9205374A (es) 1993-03-01
GR3025774T3 (en) 1998-03-31
AU653263B2 (en) 1994-09-22
CA2078814A1 (en) 1993-03-24
JPH061787A (ja) 1994-01-11
HU9203023D0 (en) 1993-11-29
ES2111025T3 (es) 1998-03-01
FI924230A (fi) 1993-03-24
CZ290692A3 (en) 1993-04-14
KR930006006A (ko) 1993-04-20
NO923686D0 (no) 1992-09-22
TW207539B (da) 1993-06-11
IL103232A0 (en) 1993-02-21
US5185350A (en) 1993-02-09
NO923686L (no) 1993-03-24
JP2961023B2 (ja) 1999-10-12
FI924230A0 (fi) 1992-09-21
EP0534343A1 (en) 1993-03-31
HUT64055A (en) 1993-11-29
ATE160346T1 (de) 1997-12-15
DE69223205D1 (de) 1998-01-02
DE69223205T2 (de) 1998-05-14

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