DK0524587T3 - Terapeutiske sammensætninger til intranasal indgivelse indeholdende Ketorolac R - Google Patents

Terapeutiske sammensætninger til intranasal indgivelse indeholdende Ketorolac R

Info

Publication number
DK0524587T3
DK0524587T3 DK92112394.9T DK92112394T DK0524587T3 DK 0524587 T3 DK0524587 T3 DK 0524587T3 DK 92112394 T DK92112394 T DK 92112394T DK 0524587 T3 DK0524587 T3 DK 0524587T3
Authority
DK
Denmark
Prior art keywords
therapeutic compositions
intranasal administration
administration containing
ketorolac
containing ketorolac
Prior art date
Application number
DK92112394.9T
Other languages
Danish (da)
English (en)
Inventor
Giancarlo Santus
Giuseppe Bottoni
Ettore Bilato
Original Assignee
Recordati Chem Pharm
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=11360400&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0524587(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Recordati Chem Pharm filed Critical Recordati Chem Pharm
Application granted granted Critical
Publication of DK0524587T3 publication Critical patent/DK0524587T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0043Nose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Otolaryngology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK92112394.9T 1991-07-22 1992-07-20 Terapeutiske sammensætninger til intranasal indgivelse indeholdende Ketorolac R DK0524587T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITMI912024A IT1250691B (it) 1991-07-22 1991-07-22 Composizioni terapeutiche per somministrazione intranasale comprendenti ketorolac.

Publications (1)

Publication Number Publication Date
DK0524587T3 true DK0524587T3 (da) 1996-04-09

Family

ID=11360400

Family Applications (1)

Application Number Title Priority Date Filing Date
DK92112394.9T DK0524587T3 (da) 1991-07-22 1992-07-20 Terapeutiske sammensætninger til intranasal indgivelse indeholdende Ketorolac R

Country Status (9)

Country Link
US (3) US6333044B1 (es)
EP (1) EP0524587B1 (es)
JP (1) JP3586735B2 (es)
AT (1) ATE130758T1 (es)
DE (1) DE69206345T2 (es)
DK (1) DK0524587T3 (es)
ES (1) ES2082288T3 (es)
GR (1) GR3019012T3 (es)
IT (1) IT1250691B (es)

Families Citing this family (54)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5883115A (en) * 1992-11-09 1999-03-16 Pharmetrix Division Technical Chemicals & Products, Inc. Transdermal delivery of the eutomer of a chiral drug
ES2095183B1 (es) * 1994-06-29 1997-12-16 S A L V A T Lab Sa Composiciones acusosas gelificantes para la administracion intranasal de farmacos.
US6596777B1 (en) 1997-05-29 2003-07-22 Mcneil-Ppc, Inc. Moisture containing compositions that are spreadable onto and adherable to biomembranes
AU714797B2 (en) * 1996-06-14 2000-01-13 Mcneil-Ppc, Inc. Moisture containing compositions that are spreadable onto and adherable to biomembranes, methods of making and use thereof
CA2312839C (en) * 1997-12-02 2008-01-15 Lisbeth Illum Compositions for nasal administration
FR2781156B1 (fr) * 1998-07-20 2001-06-29 Lafon Labor Composition pharmaceutique destinee notamment a la prevention et au traitement des radiomucites et des chimiomucites
AUPP494798A0 (en) * 1998-07-29 1998-08-20 Pacific Biolink Pty Limited Protective protein formulation
ES2173679T3 (es) * 1999-01-27 2002-10-16 Idea Ag Inmunizacion/transporte transnasal con vehiculos altamente adaptables.
SI1031346T1 (en) 1999-01-27 2002-08-31 Idea Ag Noninvasive vaccination through the skin
US20050232868A1 (en) * 1999-10-19 2005-10-20 The Procter & Gamble Company Methods of entrapping, inactivating, and removing viral infections by the administration of respiratory tract compositions
AR026073A1 (es) * 1999-10-20 2002-12-26 Nycomed Gmbh Composicion farmaceutica acuosa que contiene ciclesonida
US7977376B2 (en) 2001-06-27 2011-07-12 Novartis Ag Olopatadine formulations for topical nasal administration
TWI231759B (en) * 2001-06-27 2005-05-01 Alcon Inc Olopatadine formulations for topical administration
GB0210264D0 (en) * 2002-05-03 2002-06-12 Arakis Ltd The treatment of pain and migraine headache
US20090035260A1 (en) * 2002-07-29 2009-02-05 Therapicon Srl Enhanced nasal composition of active peptide
ITMI20021684A1 (it) * 2002-07-29 2004-01-29 Therapicon Srl Composizione farmaceutica di peptide nasale
US7166641B2 (en) * 2002-10-02 2007-01-23 Yung Shin Pharmaceutical Industrial Co., Ltd. Pharmaceutically acceptable salts containing local anesthetic and anti-inflammatory activities and methods for preparing the same
ES2312844T3 (es) * 2002-12-12 2009-03-01 Nycomed Gmbh Medicamento de combinacion de r, r-formoterol y ciclesonida.
WO2004113332A1 (ja) * 2003-06-19 2004-12-29 Ono Pharmaceutical Co., Ltd. 経鼻製剤
WO2005014046A2 (en) 2003-08-07 2005-02-17 Allergan, Inc. Compositions for delivery of therapeutics into the eyes and methods for making and using the same
DK1670482T4 (da) * 2003-09-16 2022-08-22 Covis Pharma B V Anvendelse af ciclesonid til behandlingen af respiratoriske sygdomme
US20050175679A1 (en) * 2004-02-10 2005-08-11 Michael Moshman Controlled release formulations
ITMI20040235A1 (it) * 2004-02-13 2004-05-13 Therapicon Srl Preparazione farmaceutica per il cavo orale
EP1740188A1 (en) * 2004-04-20 2007-01-10 Altana Pharma AG Use of ciclesonide for the treatment of respiratory diseases in a smoking patient
JP4966204B2 (ja) * 2004-12-23 2012-07-04 ロックスロ ファーマ, インコーポレイテッド ケトロラクの鼻腔内投与のための治療用組成物
US8546423B2 (en) 2005-05-18 2013-10-01 Mpex Pharmaceuticals, Inc. Aerosolized fluoroquinolones and uses thereof
US7838532B2 (en) * 2005-05-18 2010-11-23 Mpex Pharmaceuticals, Inc. Aerosolized fluoroquinolones and uses thereof
US20070111964A1 (en) * 2005-08-17 2007-05-17 Fleming And Company, Pharmaceuticals Vitamin B12 nasal spray and method of use
WO2009040595A1 (en) * 2007-09-28 2009-04-02 Wockhardt Research Centre Multi-dose pharmaceutical composition of analgesic for nasal administration
WO2009100383A2 (en) 2008-02-07 2009-08-13 University Of Washington Circumferential aerosol device
US7842714B2 (en) 2008-03-03 2010-11-30 Allergan, Inc. Ketorolac tromethamine compositions for treating ocular pain
US9192571B2 (en) 2008-03-03 2015-11-24 Allergan, Inc. Ketorolac tromethamine compositions for treating or preventing ocular pain
KR20110017433A (ko) * 2008-06-13 2011-02-21 록스로 파마 인코퍼레이티드 비강내 투여용 케토로락의 약학적 제형물
NZ631469A (en) 2008-10-07 2016-06-24 Raptor Pharmaceuticals Inc Aerosol fluoroquinolone formulations for improved pharmacokinetics
CN102325532B (zh) 2008-10-07 2015-06-17 Mpex医药有限公司 用于减轻肺部炎症的左氧氟沙星吸入剂
US8551454B2 (en) * 2009-03-13 2013-10-08 Luitpold Pharmaceuticals, Inc. Device for intranasal administration
US8277781B2 (en) 2009-03-13 2012-10-02 Luitpold Pharmaceuticals, Inc. Device for intranasal administration
LT2473170T (lt) 2009-09-04 2019-10-10 Horizon Orphan Llc Aerozolizuoto levofloksacino panaudojimas cistinės fibrozės gydymui
EP2605816B1 (en) * 2010-08-20 2019-01-23 University Of Washington Circumferential aerosol device for delivering drugs to olfactory epithelium and brain
CA3111516C (en) 2011-03-03 2023-05-23 Impel Neuropharma, Inc. Nasal drug delivery device
WO2012127497A1 (en) 2011-03-04 2012-09-27 Cadila Healthcare Limited Stable pharmaceutical compositions of ketorolac or salts thereof
WO2012154859A1 (en) 2011-05-09 2012-11-15 Impel Neuropharma Inc. Nozzles for nasal drug delivery
US10537692B2 (en) 2013-04-28 2020-01-21 Impel Neuropharma, Inc. Medical unit dose container
US20170027963A1 (en) * 2014-04-10 2017-02-02 Patrick Crowley Delivery of non-steroidal agents to the brain via the nasal tract to treat neurological disorders
KR20180052662A (ko) 2015-09-10 2018-05-18 임펠 뉴로파마 인코포레이티드 인-라인 코 전달 장치
EP3345592A1 (en) * 2017-01-09 2018-07-11 Michael Laird Hurrey Enhanced stability ketorolac formulations and methods and devices for use with same
US11053037B2 (en) * 2017-10-06 2021-07-06 Hikma Pharmaceuticals Usa Inc. System and method for purging oxygen from medical vials
EP3713628A4 (en) 2017-11-21 2021-08-18 Impel Neuropharma Inc. INTRA-NASAL DEVICE WITH DIVER TUBE
CA3081680A1 (en) 2017-11-21 2019-05-31 Impel Neuropharma, Inc. Intranasal device with inlet interface
EP3735223A4 (en) 2018-01-05 2021-10-13 Impel Neuropharma Inc. INTRANASAL ADMINISTRATION OF OLANZAPINE BY A PRECISION OLFACTORY DEVICE
CN111936140A (zh) 2018-01-05 2020-11-13 英倍尔药业股份有限公司 通过精密鼻装置的双氢麦角胺的鼻内递送
EP3823607A4 (en) 2018-07-19 2022-04-06 Impel NeuroPharma Inc. ADMINISTRATION OF LEVODOPA AND DOPA DECARBOXYLASE INHIBITOR INTO THE RESPIRATORY TRACT FOR THE TREATMENT OF PARKINSON'S DISEASE
US11759585B2 (en) 2019-01-03 2023-09-19 Impel Pharmaceuticals Inc. Nasal drug delivery device with detachable nozzle
WO2020236658A1 (en) 2019-05-17 2020-11-26 Impel Neuropharma, Inc. Single-use nasal delivery device

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4089569A (en) * 1976-02-19 1978-05-16 Sycor, Inc. Resilient mount for the driving shaft of an impact matrix printer and the like
US4089969A (en) 1976-07-14 1978-05-16 Syntex (U.S.A.) Inc. 5-Aroyl-1,2-dihydro-3H-pyrrolo[1,2-a]pyrrole-1-carboxylic acid derivatives and process for the production thereof
JPS539788A (en) * 1976-07-14 1978-01-28 Syntex Inc 55aloyll1*22dihydroo3hh pyroro *1*22a* pyroll11 carboxylic acid derivative
US4284648A (en) * 1979-08-03 1981-08-18 The University Of Kentucky Research Foundation Nasal administration of propranolol
CH657779A5 (de) * 1982-10-05 1986-09-30 Sandoz Ag Galenische zusammensetzungen enthaltend calcitonin.
US4478822A (en) 1983-05-16 1984-10-23 Merck & Co., Inc. Drug delivery system utilizing thermosetting gels
IT1169873B (it) * 1983-10-21 1987-06-03 Prodotti Formenti Srl Composizione farmaceutica ad attivita' sistemica anticolinesterasica, agonista-colinergica ed antimuscarinica
US5049386A (en) * 1985-01-07 1991-09-17 Syntex (U.S.A.) Inc. N-ω,(ω-1)-dialkyloxy)- and N-(ω,(ω-1)-dialkenyloxy)Alk-1-YL-N,N,N-tetrasubstituted ammonium lipids and uses therefor
US5122127A (en) * 1985-05-01 1992-06-16 University Of Utah Apparatus and methods for use in administering medicaments by direct medicament contact to mucosal tissues
DE3601923A1 (de) * 1986-01-23 1987-07-30 Behringwerke Ag Nasal applizierbares arzneimittel, verfahren zu seiner herstellung und seine verwendung
CA1291036C (en) * 1986-04-23 1991-10-22 Edwin I. Stoltz Nasal administration of drugs
US4919939A (en) * 1986-04-29 1990-04-24 Pharmetrix Corporation Periodontal disease treatment system
NZ222907A (en) * 1986-12-16 1990-08-28 Novo Industri As Preparation for intranasal administration containing a phospholipid absorption enhancing system
US4778810A (en) 1987-01-08 1988-10-18 Nastech Pharmaceutical Co., Inc. Nasal delivery of caffeine
US5414011A (en) * 1987-09-11 1995-05-09 Syntex (U.S.A.) Inc. Preservative system for ophthalmic formulations
US4943587A (en) * 1988-05-19 1990-07-24 Warner-Lambert Company Hydroxamate derivatives of selected nonsteroidal antiinflammatory acyl residues and their use for cyclooxygenase and 5-lipoxygenase inhibition
US4973596A (en) * 1988-05-20 1990-11-27 Barr Laboratories, Inc. Method of administering a narcotic analgesic and dosage forms therefor
US4885287A (en) * 1988-08-09 1989-12-05 University Of Kentucky Research Foundation Novel method of administering aspirin and dosage forms containing same
GB8900267D0 (en) 1989-01-06 1989-03-08 Riker Laboratories Inc Narcotic analgesic formulations and apparatus containing same
US4994439A (en) * 1989-01-19 1991-02-19 California Biotechnology Inc. Transmembrane formulations for drug administration
JPH07112984B2 (ja) * 1989-04-28 1995-12-06 久光製薬株式会社 泡状エアゾール製剤
US5091182A (en) * 1990-07-23 1992-02-25 Syntex (U.S.A.) Inc. Dispensing units for ketorolac topical gel formlations
US5143731A (en) * 1990-08-07 1992-09-01 Mediventures Incorporated Body cavity drug delivery with thermo-irreversible polyoxyalkylene and ionic polysaccharide gels
US5855907A (en) * 1997-03-24 1999-01-05 Peyman; Gholam A. Method of treatment of migraine
US6090368A (en) * 1998-03-03 2000-07-18 The Board Of Governors For Higher Education, State Of Rhode Island And Providence Plantations Pharmaceutical compositions for intranasal spray administration of ketorolac tromethamine

Also Published As

Publication number Publication date
ATE130758T1 (de) 1995-12-15
ITMI912024A0 (it) 1991-07-22
DE69206345T2 (de) 1996-04-25
ITMI912024A1 (it) 1993-01-23
US7476689B2 (en) 2009-01-13
DE69206345D1 (de) 1996-01-11
US6333044B1 (en) 2001-12-25
IT1250691B (it) 1995-04-21
EP0524587B1 (en) 1995-11-29
JP3586735B2 (ja) 2004-11-10
GR3019012T3 (en) 1996-05-31
US20040171666A1 (en) 2004-09-02
JPH05194215A (ja) 1993-08-03
US20020077346A1 (en) 2002-06-20
EP0524587A1 (en) 1993-01-27
ES2082288T3 (es) 1996-03-16
US7267827B2 (en) 2007-09-11

Similar Documents

Publication Publication Date Title
DK0524587T3 (da) Terapeutiske sammensætninger til intranasal indgivelse indeholdende Ketorolac R
DK383987A (da) Ny galeniske formuleringer med programmeret afgivelse indeholdende antiphlogistika
DK0510404T3 (da) Gastroresistente farmaceutiske formuleringer til oral administration indeholdende galdesyresalte
NO991056D0 (no) Rene enantiomere basiske aryl-cykloalkyl-hydroksykarboksylsyreestere, fremgangsmÕte for deres fremstilling og anvendelse derav i medikamenter
DK0503440T3 (da) Sumatriptanholdige lægemidler
CA2301017A1 (en) Use of propyl gallate to increase bioavailability of orally administered pharmaceutical compounds
DK0562956T3 (da) Hidtil ukendte naphthylalkylaminer, fremgangsmåde til fremstilling heraf og farmaceutiske midler, som indeholder dem
DE69628163D1 (de) Nor-pregnane zur induzierung hypothalamischer effekte
MY129473A (en) 3,3-diarylpropylamines, their use and preparation
DK0652000T3 (da) Anvendelse af 2-phenyl-3-aroylbenzothiophener til fremstilling af et lægemiddel til inhibering af angiogenese og angiogene sygdomme
ATE38151T1 (de) Bestaendige 5-adenosyl-l-methionin-salze enthaltende, pharmazeutische zusammensetzungen fuer orale anwendung.
AP9901474A0 (en) Pharmaceutical composition for treating viral diseases.
DK0571243T3 (da) Thiochromanderivater, fremgangsmåder til fremstilling heraf samt farmaceutiske midler indeholdende d isse
MY133438A (en) Morpholinobenzamide salts
DE69522827D1 (de) Fibrinogen receptor antagonisten mit substituierten b-aminosäurenestern und diese enthaltende pharmazeutische präparate
MX9302929A (es) Derivados de tetrahidro y perhidroisoquinolina y medios terapeuticos que los contienen.
MX9702532A (es) Composiciones farmaceuticas para el tratamiento de la rinitis.