ES2082288T3 - Composiciones terapeuticas para administracion intranasal de ketorolaco. - Google Patents

Composiciones terapeuticas para administracion intranasal de ketorolaco.

Info

Publication number
ES2082288T3
ES2082288T3 ES92112394T ES92112394T ES2082288T3 ES 2082288 T3 ES2082288 T3 ES 2082288T3 ES 92112394 T ES92112394 T ES 92112394T ES 92112394 T ES92112394 T ES 92112394T ES 2082288 T3 ES2082288 T3 ES 2082288T3
Authority
ES
Spain
Prior art keywords
therapeutic compositions
intranasal administration
ketorolaco
pirrolic
racemically
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES92112394T
Other languages
English (en)
Inventor
Giancarlo Santus
Giuseppe Bottoni
Ettore Bilato
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Recordati SA
Original Assignee
Recordati SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=11360400&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2082288(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Recordati SA filed Critical Recordati SA
Application granted granted Critical
Publication of ES2082288T3 publication Critical patent/ES2082288T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Otolaryngology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

NUEVAS COMPOSICIONES TERAPEUTICAS CON ACTIVIDAD ANALGESICA Y ANTI-INFLAMATORIA, DE ADMINISTRACION INTRANASAL QUE CONTIENEN COMO INGREDIENTE ACTIVO UNA CANTIDAD EFECTIVA, DE 0,5 A 40 MG POR DOSIS, DE ACIDO 5-BENZOIL-2,3-DIHIDRO-1H-PIRROLICINA-1CARBOXILICO (KETOROLAC TM) A MODO RACEMICO U OPTICAMENTE ACTIVO O SALES TERAPEUTICAMENTE ACEPTABLES DEL MISMO.
ES92112394T 1991-07-22 1992-07-20 Composiciones terapeuticas para administracion intranasal de ketorolaco. Expired - Lifetime ES2082288T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITMI912024A IT1250691B (it) 1991-07-22 1991-07-22 Composizioni terapeutiche per somministrazione intranasale comprendenti ketorolac.

Publications (1)

Publication Number Publication Date
ES2082288T3 true ES2082288T3 (es) 1996-03-16

Family

ID=11360400

Family Applications (1)

Application Number Title Priority Date Filing Date
ES92112394T Expired - Lifetime ES2082288T3 (es) 1991-07-22 1992-07-20 Composiciones terapeuticas para administracion intranasal de ketorolaco.

Country Status (9)

Country Link
US (3) US6333044B1 (es)
EP (1) EP0524587B1 (es)
JP (1) JP3586735B2 (es)
AT (1) ATE130758T1 (es)
DE (1) DE69206345T2 (es)
DK (1) DK0524587T3 (es)
ES (1) ES2082288T3 (es)
GR (1) GR3019012T3 (es)
IT (1) IT1250691B (es)

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JP2011524366A (ja) * 2008-06-13 2011-09-01 ロクスロ・ファーマ・インコーポレイテッド 鼻内投与のためのケトロラクの薬学的処方物
US8815838B2 (en) 2008-10-07 2014-08-26 David C. Griffith Aerosol fluoroquinolone formulations for improved pharmacokinetics
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US20130142868A1 (en) * 2010-08-20 2013-06-06 University Of Washington Circumferential Aerosol Device for Delivering Drugs to Olfactory Epithelium and Brain
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EP3129013A1 (en) * 2014-04-10 2017-02-15 Crowley, Patrick Delivery of non-steroidal antiinflammatory agents to the brain via the nasal tract to treat neurological disorders
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CA2991388A1 (en) * 2017-01-09 2018-07-09 Michael Laird Hurrey Enhanced stability ketorolac formulations and methods and devices for use with same
US11053037B2 (en) * 2017-10-06 2021-07-06 Hikma Pharmaceuticals Usa Inc. System and method for purging oxygen from medical vials
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CN112955134A (zh) 2018-07-19 2021-06-11 英倍尔药业股份有限公司 用于治疗帕金森氏病的左旋多巴和多巴脱羧酶抑制剂的呼吸道递送
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Also Published As

Publication number Publication date
ITMI912024A0 (it) 1991-07-22
US7267827B2 (en) 2007-09-11
IT1250691B (it) 1995-04-21
EP0524587A1 (en) 1993-01-27
EP0524587B1 (en) 1995-11-29
ATE130758T1 (de) 1995-12-15
ITMI912024A1 (it) 1993-01-23
US6333044B1 (en) 2001-12-25
US20020077346A1 (en) 2002-06-20
DE69206345D1 (de) 1996-01-11
DK0524587T3 (da) 1996-04-09
JP3586735B2 (ja) 2004-11-10
GR3019012T3 (en) 1996-05-31
DE69206345T2 (de) 1996-04-25
US7476689B2 (en) 2009-01-13
JPH05194215A (ja) 1993-08-03
US20040171666A1 (en) 2004-09-02

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