DK0562956T3 - Hidtil ukendte naphthylalkylaminer, fremgangsmåde til fremstilling heraf og farmaceutiske midler, som indeholder dem - Google Patents
Hidtil ukendte naphthylalkylaminer, fremgangsmåde til fremstilling heraf og farmaceutiske midler, som indeholder demInfo
- Publication number
- DK0562956T3 DK0562956T3 DK93400757.6T DK93400757T DK0562956T3 DK 0562956 T3 DK0562956 T3 DK 0562956T3 DK 93400757 T DK93400757 T DK 93400757T DK 0562956 T3 DK0562956 T3 DK 0562956T3
- Authority
- DK
- Denmark
- Prior art keywords
- naphthylalkylamines
- preparation
- new
- methods
- pharmaceutical agents
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/57—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of rings other than six-membered aromatic rings
- C07C233/63—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of rings other than six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/02—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
- C07C233/04—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals with carbon atoms of carboxamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
- C07C233/05—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals with carbon atoms of carboxamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/57—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of rings other than six-membered aromatic rings
- C07C233/58—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of rings other than six-membered aromatic rings having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/57—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of rings other than six-membered aromatic rings
- C07C233/60—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of rings other than six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C275/04—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms
- C07C275/20—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms of an unsaturated carbon skeleton
- C07C275/24—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/02—Systems containing only non-condensed rings with a three-membered ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/04—Systems containing only non-condensed rings with a four-membered ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
- C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/16—Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Dermatology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9203700A FR2689124A1 (fr) | 1992-03-27 | 1992-03-27 | Nouvelles naphtylalkylamines, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent. |
Publications (1)
Publication Number | Publication Date |
---|---|
DK0562956T3 true DK0562956T3 (da) | 1996-02-05 |
Family
ID=9428140
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK93400757.6T DK0562956T3 (da) | 1992-03-27 | 1993-03-24 | Hidtil ukendte naphthylalkylaminer, fremgangsmåde til fremstilling heraf og farmaceutiske midler, som indeholder dem |
Country Status (13)
Country | Link |
---|---|
US (2) | US5420158A (da) |
EP (1) | EP0562956B1 (da) |
JP (1) | JPH0749404B2 (da) |
AT (1) | ATE128458T1 (da) |
AU (1) | AU657400B2 (da) |
CA (1) | CA2092794C (da) |
DE (1) | DE69300532T2 (da) |
DK (1) | DK0562956T3 (da) |
ES (1) | ES2081187T3 (da) |
FR (1) | FR2689124A1 (da) |
GR (1) | GR3018212T3 (da) |
NZ (1) | NZ247266A (da) |
ZA (1) | ZA932168B (da) |
Families Citing this family (36)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0528762B1 (de) * | 1991-08-15 | 1997-05-07 | Novartis AG | N-Acyl-N-Heterocyclyl- oder Naphthylalkyl-Aminosäuren als Angiotensin II Antagonisten |
US5719147A (en) * | 1992-06-29 | 1998-02-17 | Merck & Co., Inc. | Morpholine and thiomorpholine tachykinin receptor antagonists |
US6048859A (en) * | 1992-06-29 | 2000-04-11 | Merck & Co., Inc. | Morpholine and thiomorpholine tachykinin receptor antagonists |
FR2713636B1 (fr) * | 1993-12-07 | 1996-01-05 | Adir | Nouveaux dérivés naphtaléniques, leur procédé de préparation, et les compositions pharmaceutiques qui les contiennent. |
US5958683A (en) * | 1994-03-30 | 1999-09-28 | Novartis Corporation | Screening method using the RZR receptor family |
US5849769A (en) | 1994-08-24 | 1998-12-15 | Medivir Ab | N-arylalkyl-N-heteroarylurea and guandine compounds and methods of treating HIV infection |
AU3399895A (en) | 1994-09-12 | 1996-03-29 | Takeda Chemical Industries Ltd. | Benzocycloalkene compounds, their production and use |
US5541228A (en) * | 1994-10-14 | 1996-07-30 | Bristol-Myers Squibb Co. | Melatonergic agents |
FR2725985B1 (fr) * | 1994-10-21 | 1996-11-15 | Adir | Nouveaux composes tricycliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
US6071946A (en) * | 1994-10-21 | 2000-06-06 | Adir Et Compagnie | Tricyclic urea compounds |
US5998461A (en) * | 1994-10-21 | 1999-12-07 | Adir Et Compagnie | Tricyclic amide compounds |
US5530012A (en) | 1994-12-22 | 1996-06-25 | Bristol-Myers Squibb Co. | 3-alkoxybenzylpiperidine derivatives as melatonergic agents |
FR2729147A1 (fr) * | 1995-01-11 | 1996-07-12 | Adir | Nouveaux composes (hetero) cycliques alkyles, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
US5661186A (en) * | 1995-02-24 | 1997-08-26 | Bristol-Myers Squibb Co. | Tetralinyl-and indanyl-ethylamides |
US6310085B1 (en) | 1997-10-03 | 2001-10-30 | Clarencew Pty Ltd. | Method for the treatment of neurological or neuropsychiatric disorders |
AUPO274596A0 (en) * | 1996-10-04 | 1996-10-31 | Armstrong, Stuart Maxwell | Method for the treatment of neurological or neuropsychiatric disorders |
WO1998025606A1 (en) * | 1996-12-10 | 1998-06-18 | Bristol-Myers Squibb Company | Benzodioxole, benzofuran, dihydrobenzofuran, and benzodioxane melatonergic agents |
US6028112A (en) * | 1997-05-23 | 2000-02-22 | Bristol-Myers Squibb Company | Spirocyclopropyl fluorenes as melatonergic agents |
FR2778662B1 (fr) | 1998-05-12 | 2000-06-16 | Adir | Nouveaux composes cycliques substitues, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
CA2334299A1 (en) * | 1998-06-05 | 1999-12-09 | Pierre Dextraze | Heterocyclic cis cyclopropane derivatives as melatonergic agents |
US6617351B1 (en) | 1998-07-31 | 2003-09-09 | Eli Lilly And Company | Amide, carbamate, and urea derivatives |
PE20000942A1 (es) * | 1998-07-31 | 2000-09-28 | Lilly Co Eli | Derivados de amida, carbamato y urea |
FR2793793B1 (fr) * | 1999-05-19 | 2004-02-27 | Adir | Nouveaux derives dimeriques substitues, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
WO2001002392A1 (en) | 1999-06-30 | 2001-01-11 | Bristol-Myers Squibb Company | Heterocyclic aminopyrrolidine derivatives as melatonergic agents |
US6952041B2 (en) | 2003-07-25 | 2005-10-04 | Robert Bosch Gmbh | Anchors for microelectromechanical systems having an SOI substrate, and method of fabricating same |
FR2903101B1 (fr) * | 2006-06-30 | 2008-09-26 | Servier Lab | Nouveaux derives naphtaleniques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
FR2903103B1 (fr) * | 2006-06-30 | 2010-08-13 | Servier Lab | Nouveaux derives naphtaleniques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
FR2903102B1 (fr) * | 2006-06-30 | 2010-08-13 | Servier Lab | Nouveaux derives naphtaleniques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
AU2008247805A1 (en) * | 2007-05-01 | 2008-11-13 | Concert Pharmaceuticals Inc. | Naphthyl(ethyl) acetamides |
FR2918370B1 (fr) * | 2007-07-02 | 2009-08-28 | Servier Lab | Nouveaux derives naphtaleniques,leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
FR2918372B1 (fr) * | 2007-07-02 | 2009-08-28 | Servier Lab | Nouveaux derives naphtaleniques,leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
AU2013280236B2 (en) | 2012-06-29 | 2016-12-08 | Johnson & Johnson Vision Care, Inc. | Multiple state electroactive ophthalmic device |
EP2909166A4 (en) * | 2012-10-22 | 2016-10-26 | Symed Labs Ltd | PROCESS FOR THE PREPARATION OF AGOMALATIN USING NEW INTERMEDIATES |
WO2016046833A2 (en) * | 2014-09-24 | 2016-03-31 | Symed Labs Limited | Improved processes for the preparation of agomelatine using novel intermediates |
CN107325011A (zh) * | 2016-04-30 | 2017-11-07 | 陕西合成药业股份有限公司 | 一种褪黑激素类化合物及其制备方法和用途 |
TW202214558A (zh) * | 2020-07-28 | 2022-04-16 | 大陸商上海翰森生物醫藥科技有限公司 | 雙環類衍生物調節劑、其製備方法和應用 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4916223A (en) * | 1986-08-28 | 1990-04-10 | Merck & Co., Inc. | Substituted hexahydroarylquinolizines |
JPH0678298B2 (ja) * | 1988-03-30 | 1994-10-05 | ワーナー‐ランバート・コンパニー | N‐〔〔(2,6‐ジ置換)フエニル〕‐n′‐アリールアルキル〕尿素 |
DE3828566A1 (de) * | 1988-08-23 | 1990-03-15 | Thomae Gmbh Dr K | Neue benzolsulfonamido-verbindungen, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung |
FR2658818B1 (fr) * | 1990-02-27 | 1993-12-31 | Adir Cie | Nouveaux derives a structure naphtalenique, leur procede de preparation et les compositions pharmaceutiques qui les contiennent. |
-
1992
- 1992-03-27 FR FR9203700A patent/FR2689124A1/fr not_active Withdrawn
-
1993
- 1993-03-23 US US08/035,936 patent/US5420158A/en not_active Expired - Fee Related
- 1993-03-24 DE DE69300532T patent/DE69300532T2/de not_active Expired - Fee Related
- 1993-03-24 ES ES93400757T patent/ES2081187T3/es not_active Expired - Lifetime
- 1993-03-24 EP EP93400757A patent/EP0562956B1/fr not_active Expired - Lifetime
- 1993-03-24 DK DK93400757.6T patent/DK0562956T3/da active
- 1993-03-24 AT AT93400757T patent/ATE128458T1/de not_active IP Right Cessation
- 1993-03-26 NZ NZ247266A patent/NZ247266A/en unknown
- 1993-03-26 JP JP5105844A patent/JPH0749404B2/ja not_active Expired - Fee Related
- 1993-03-26 AU AU35445/93A patent/AU657400B2/en not_active Ceased
- 1993-03-26 ZA ZA932168A patent/ZA932168B/xx unknown
- 1993-03-26 CA CA002092794A patent/CA2092794C/fr not_active Expired - Fee Related
-
1995
- 1995-01-25 US US08/377,812 patent/US5616614A/en not_active Expired - Fee Related
- 1995-11-27 GR GR950403327T patent/GR3018212T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
JPH0649011A (ja) | 1994-02-22 |
ZA932168B (en) | 1993-11-08 |
ATE128458T1 (de) | 1995-10-15 |
US5616614A (en) | 1997-04-01 |
DE69300532T2 (de) | 1996-05-15 |
ES2081187T3 (es) | 1996-02-16 |
NZ247266A (en) | 1995-09-26 |
EP0562956A1 (fr) | 1993-09-29 |
AU3544593A (en) | 1993-09-30 |
JPH0749404B2 (ja) | 1995-05-31 |
AU657400B2 (en) | 1995-03-09 |
GR3018212T3 (en) | 1996-02-29 |
FR2689124A1 (fr) | 1993-10-01 |
DE69300532D1 (de) | 1995-11-02 |
CA2092794A1 (fr) | 1993-09-28 |
US5420158A (en) | 1995-05-30 |
EP0562956B1 (fr) | 1995-09-27 |
CA2092794C (fr) | 1999-03-23 |
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