DK0427636T3 - 4-acylaminopyridin-derivater - Google Patents

4-acylaminopyridin-derivater

Info

Publication number
DK0427636T3
DK0427636T3 DK90403182.0T DK90403182T DK0427636T3 DK 0427636 T3 DK0427636 T3 DK 0427636T3 DK 90403182 T DK90403182 T DK 90403182T DK 0427636 T3 DK0427636 T3 DK 0427636T3
Authority
DK
Denmark
Prior art keywords
acylaminopyridin
derivatives
acylaminopyridine derivative
alzheimer
chem
Prior art date
Application number
DK90403182.0T
Other languages
Danish (da)
English (en)
Inventor
Kunihiro Ninomiya
Kenichi Saito
Mamoru Sugano
Akihiro Tobe
Yasuhiro Morinaka
Tomoko Bessho
Haruko Harada
Original Assignee
Mitsubishi Chem Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP1290916A external-priority patent/JP2720549B2/ja
Application filed by Mitsubishi Chem Corp filed Critical Mitsubishi Chem Corp
Application granted granted Critical
Publication of DK0427636T3 publication Critical patent/DK0427636T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/20—Spiro-condensed ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D219/00—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
    • C07D219/04—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
    • C07D219/08—Nitrogen atoms
    • C07D219/10—Nitrogen atoms attached in position 9
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/04—Ortho- or peri-condensed ring systems
    • C07D221/06—Ring systems of three rings
    • C07D221/16—Ring systems of three rings containing carbocyclic rings other than six-membered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/22—Bridged ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
DK90403182.0T 1989-11-08 1990-11-08 4-acylaminopyridin-derivater DK0427636T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP29091589 1989-11-08
JP1290916A JP2720549B2 (ja) 1989-11-08 1989-11-08 ９―アミノアセチルアミノテトラヒドロアクリジン誘導体
JP29091889 1989-11-08

Publications (1)

Publication Number Publication Date
DK0427636T3 true DK0427636T3 (da) 1996-10-14

Family

ID=27337617

Family Applications (1)

Application Number Title Priority Date Filing Date
DK90403182.0T DK0427636T3 (da) 1989-11-08 1990-11-08 4-acylaminopyridin-derivater

Country Status (9)

Country Link
US (3) US5397785A (ko)
EP (1) EP0427636B1 (ko)
KR (1) KR100192833B1 (ko)
AT (1) ATE138653T1 (ko)
CA (1) CA2029497C (ko)
DE (1) DE69027180T2 (ko)
DK (1) DK0427636T3 (ko)
ES (1) ES2088998T3 (ko)
GR (1) GR3020868T3 (ko)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0638071T3 (da) * 1992-12-28 1997-10-27 Eisai Co Ltd Heterocykliske carboxylsyrederivater, der bindes til retenoidreceptorer (RAR)
US5852041A (en) * 1993-04-07 1998-12-22 Sibia Neurosciences, Inc. Substituted pyridines useful as modulators of acethylcholine receptors
JPH0892100A (ja) * 1994-09-21 1996-04-09 Mitsubishi Chem Corp 神経系障害の治療および予防薬
US5585388A (en) * 1995-04-07 1996-12-17 Sibia Neurosciences, Inc. Substituted pyridines useful as modulators of acetylcholine receptors
US5794887A (en) 1995-11-17 1998-08-18 Komerath; Narayanan M. Stagnation point vortex controller
WO2002085910A1 (en) * 2001-04-19 2002-10-31 Mitsubishi Pharma Corporation Polymorph forms of n-(2,3-dimethyl-5,6,7,8-tetrahydrofuro[2,3-b]quinolin-4-yl)-2-(2- oxopyrrolidin -1 -yl)acetamide
CA2456594A1 (en) * 2001-08-06 2003-02-20 Mitsubishi Pharma Corporation Preventives/remedies for cholinergic neuropathy
US7332508B2 (en) * 2002-12-18 2008-02-19 Novo Nordisk A/S Substituted homopiperidine, piperidine or pyrrolidine derivatives
WO2004063201A1 (ja) * 2003-01-08 2004-07-29 Mitsubishi Pharma Corporation 統合失調症治療剤
US20050222123A1 (en) 2004-01-27 2005-10-06 North Shore-Long Island Jewish Research Institute Cholinesterase inhibitors for treating inflammation
JP2009525979A (ja) * 2006-02-07 2009-07-16 田辺三菱製薬株式会社 ４−アシルアミノピリジン誘導体を介した神経新生
KR20090064418A (ko) 2006-09-08 2009-06-18 브레인셀즈 인코퍼레이션 4-아실아미노피리딘 유도체 포함 조합물
CN102341402A (zh) * 2009-01-05 2012-02-01 科学与工业研究委员会 作为药理活性剂的噻吩并吡啶类化合物
WO2011070177A2 (en) * 2009-12-11 2011-06-16 Baltic Technology Development, Ltd. Methods of facilitating neural cell survival using gdnf family ligand (gfl) mimetics or ret signaling pathway activators
CN102219740B (zh) * 2010-09-10 2013-02-13 长春华洋高科技有限公司 1，2，3，4，5，6，7，8-八氢-9-苯乙酰胺基吖啶及制备方法和药用用途
CZ202135A3 (cs) * 2021-01-26 2022-06-29 Fakultní nemocnice Hradec Králové Duálně účinné deriváty takrinu a jejich použití

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4753950A (en) * 1986-11-24 1988-06-28 Hoechst-Roussel Pharmaceuticals, Inc. Fused heterocyclic tetrahydroaminoquinolinols and related compounds
JPH0696575B2 (ja) * 1987-09-17 1994-11-30 三菱化成株式会社 ４−アミノピリジン誘導体及びその酸付加塩
WO1989002739A1 (en) * 1987-10-05 1989-04-06 Pfizer Inc. 4-aminopyridine derivatives
US4985430A (en) * 1987-12-03 1991-01-15 Mitsubishi Kasei Corporation 9-acylamino-tetrahydroacridine derivatives and memory enhancing agent containing said derivative as active ingredient
US4999430A (en) * 1989-07-31 1991-03-12 Warner-Lambert Company Derivatives of 1,2,3,4-tetrahydro-9-acrisinamine

Also Published As

Publication number Publication date
GR3020868T3 (en) 1996-11-30
CA2029497A1 (en) 1991-05-09
KR100192833B1 (ko) 1999-06-15
EP0427636B1 (en) 1996-05-29
CA2029497C (en) 2002-06-04
US5536728A (en) 1996-07-16
US5861411A (en) 1999-01-19
DE69027180D1 (de) 1996-07-04
KR910009667A (ko) 1991-06-28
DE69027180T2 (de) 1997-01-09
EP0427636A2 (en) 1991-05-15
ATE138653T1 (de) 1996-06-15
ES2088998T3 (es) 1996-10-01
US5397785A (en) 1995-03-14
EP0427636A3 (en) 1991-11-06

Similar Documents

Publication Publication Date Title
DK0427636T3 (da) 4-acylaminopyridin-derivater
MX9304996A (es) Heterociclos no-aromaticos que contienen bencilamino nitrogeno substituido.
IE891379L (en) Benzopyrido piperidine, piperidylidene and piperazine¹compounds
DE69634678D1 (de) Verbesserung oder heilung von durch ischämischen krankheiten hervorgerufenen symtomen und dafür verwendbare phenylpiperidinverbingungen
DE69002996D1 (de) Triphenylmethan-Derivate.
FI915920A0 (fi) Serotoninantagonister.
ATE112560T1 (de) Piperidinoalkyl-derivate von carbonsäure-amiden.
DE69326395D1 (de) Spirooxathiolan-quinuclidin-Derivat zur Behandlung des Sjögren-Syndroms
ATE123024T1 (de) 4-aminopyridinderivate.
FI896289A0 (fi) Svavelhaltiga heterocykliska foereningar.
DE69409338D1 (de) Sialinsauer-Amide von 3-Aminosterinen
FI883961A (fi) Farmaceutiskt nyttig polymorfisk modifikation av buspiron.
AU565519B2 (en) Pyridyl piperidinedione derivatives and their use as anti-arrhythmics
DE59207425D1 (de) Imidazolylmethyl-Pyridine
NO904135D0 (no) Fremgangsmaate for fremstilling av nye alkylpiperidiner.
FI883869A (fi) Foerfarande foer framstaellning av nya derivat av 1,2,5,6-tetrahydropyridin-3-karboxaldehydoxim.
NO177053C (no) Analogifremgangsmåte for fremstilling av terapeutisk aktive (1,2,3,4-tetrahydro-9-akridinimino)cykloheksankarboksylsyrer
HUT63197A (en) Process for producing new antibacterial compounds
FI913506A0 (fi) Foerfarande foer framstaellning av 6-(substituerat aminopropionyl)-derivat av forskolin.
DE69401521D1 (de) Piperidin-Derivate mit antihistaminischer und antileukomenischer Wirkung
PT92668A (pt) Processo para a preparacao de derivados de azabiciclo-heptano
DK0437645T3 (da) Imidazolylpropylguanidinderivat, fremgangsmåde til fremstilling deraf og lægemidler indeholdende denne forbindelse