DE69027180D1 - 4-Acylaminopyridin-Derivate - Google Patents
4-Acylaminopyridin-DerivateInfo
- Publication number
- DE69027180D1 DE69027180D1 DE69027180T DE69027180T DE69027180D1 DE 69027180 D1 DE69027180 D1 DE 69027180D1 DE 69027180 T DE69027180 T DE 69027180T DE 69027180 T DE69027180 T DE 69027180T DE 69027180 D1 DE69027180 D1 DE 69027180D1
- Authority
- DE
- Germany
- Prior art keywords
- acylaminopyridine
- acylaminopyridine derivative
- acylaminopyridine derivatives
- derivatives
- alzheimer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/20—Spiro-condensed ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D219/00—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
- C07D219/04—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
- C07D219/08—Nitrogen atoms
- C07D219/10—Nitrogen atoms attached in position 9
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/04—Ortho- or peri-condensed ring systems
- C07D221/06—Ring systems of three rings
- C07D221/16—Ring systems of three rings containing carbocyclic rings other than six-membered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/22—Bridged ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP29091589 | 1989-11-08 | ||
JP1290916A JP2720549B2 (ja) | 1989-11-08 | 1989-11-08 | 9―アミノアセチルアミノテトラヒドロアクリジン誘導体 |
JP29091889 | 1989-11-08 |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69027180D1 true DE69027180D1 (de) | 1996-07-04 |
DE69027180T2 DE69027180T2 (de) | 1997-01-09 |
Family
ID=27337617
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69027180T Expired - Lifetime DE69027180T2 (de) | 1989-11-08 | 1990-11-08 | 4-Acylaminopyridin-Derivate |
Country Status (9)
Country | Link |
---|---|
US (3) | US5397785A (de) |
EP (1) | EP0427636B1 (de) |
KR (1) | KR100192833B1 (de) |
AT (1) | ATE138653T1 (de) |
CA (1) | CA2029497C (de) |
DE (1) | DE69027180T2 (de) |
DK (1) | DK0427636T3 (de) |
ES (1) | ES2088998T3 (de) |
GR (1) | GR3020868T3 (de) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK0638071T3 (da) * | 1992-12-28 | 1997-10-27 | Eisai Co Ltd | Heterocykliske carboxylsyrederivater, der bindes til retenoidreceptorer (RAR) |
US5852041A (en) * | 1993-04-07 | 1998-12-22 | Sibia Neurosciences, Inc. | Substituted pyridines useful as modulators of acethylcholine receptors |
JPH0892100A (ja) * | 1994-09-21 | 1996-04-09 | Mitsubishi Chem Corp | 神経系障害の治療および予防薬 |
US5585388A (en) * | 1995-04-07 | 1996-12-17 | Sibia Neurosciences, Inc. | Substituted pyridines useful as modulators of acetylcholine receptors |
US5794887A (en) | 1995-11-17 | 1998-08-18 | Komerath; Narayanan M. | Stagnation point vortex controller |
WO2002085910A1 (en) * | 2001-04-19 | 2002-10-31 | Mitsubishi Pharma Corporation | Polymorph forms of n-(2,3-dimethyl-5,6,7,8-tetrahydrofuro[2,3-b]quinolin-4-yl)-2-(2- oxopyrrolidin -1 -yl)acetamide |
CA2456594A1 (en) * | 2001-08-06 | 2003-02-20 | Mitsubishi Pharma Corporation | Preventives/remedies for cholinergic neuropathy |
US7332508B2 (en) * | 2002-12-18 | 2008-02-19 | Novo Nordisk A/S | Substituted homopiperidine, piperidine or pyrrolidine derivatives |
WO2004063201A1 (ja) * | 2003-01-08 | 2004-07-29 | Mitsubishi Pharma Corporation | 統合失調症治療剤 |
US20050222123A1 (en) | 2004-01-27 | 2005-10-06 | North Shore-Long Island Jewish Research Institute | Cholinesterase inhibitors for treating inflammation |
JP2009525979A (ja) * | 2006-02-07 | 2009-07-16 | 田辺三菱製薬株式会社 | 4−アシルアミノピリジン誘導体を介した神経新生 |
KR20090064418A (ko) | 2006-09-08 | 2009-06-18 | 브레인셀즈 인코퍼레이션 | 4-아실아미노피리딘 유도체 포함 조합물 |
CN102341402A (zh) * | 2009-01-05 | 2012-02-01 | 科学与工业研究委员会 | 作为药理活性剂的噻吩并吡啶类化合物 |
WO2011070177A2 (en) * | 2009-12-11 | 2011-06-16 | Baltic Technology Development, Ltd. | Methods of facilitating neural cell survival using gdnf family ligand (gfl) mimetics or ret signaling pathway activators |
CN102219740B (zh) * | 2010-09-10 | 2013-02-13 | 长春华洋高科技有限公司 | 1,2,3,4,5,6,7,8-八氢-9-苯乙酰胺基吖啶及制备方法和药用用途 |
CZ202135A3 (cs) * | 2021-01-26 | 2022-06-29 | Fakultní nemocnice Hradec Králové | Duálně účinné deriváty takrinu a jejich použití |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4753950A (en) * | 1986-11-24 | 1988-06-28 | Hoechst-Roussel Pharmaceuticals, Inc. | Fused heterocyclic tetrahydroaminoquinolinols and related compounds |
JPH0696575B2 (ja) * | 1987-09-17 | 1994-11-30 | 三菱化成株式会社 | 4−アミノピリジン誘導体及びその酸付加塩 |
WO1989002739A1 (en) * | 1987-10-05 | 1989-04-06 | Pfizer Inc. | 4-aminopyridine derivatives |
US4985430A (en) * | 1987-12-03 | 1991-01-15 | Mitsubishi Kasei Corporation | 9-acylamino-tetrahydroacridine derivatives and memory enhancing agent containing said derivative as active ingredient |
US4999430A (en) * | 1989-07-31 | 1991-03-12 | Warner-Lambert Company | Derivatives of 1,2,3,4-tetrahydro-9-acrisinamine |
-
1990
- 1990-11-07 CA CA002029497A patent/CA2029497C/en not_active Expired - Lifetime
- 1990-11-08 ES ES90403182T patent/ES2088998T3/es not_active Expired - Lifetime
- 1990-11-08 DK DK90403182.0T patent/DK0427636T3/da active
- 1990-11-08 EP EP90403182A patent/EP0427636B1/de not_active Expired - Lifetime
- 1990-11-08 AT AT90403182T patent/ATE138653T1/de not_active IP Right Cessation
- 1990-11-08 KR KR1019900018017A patent/KR100192833B1/ko not_active IP Right Cessation
- 1990-11-08 DE DE69027180T patent/DE69027180T2/de not_active Expired - Lifetime
-
1993
- 1993-09-02 US US08/115,257 patent/US5397785A/en not_active Expired - Lifetime
-
1994
- 1994-12-08 US US08/355,181 patent/US5536728A/en not_active Expired - Lifetime
-
1996
- 1996-04-10 US US08/629,901 patent/US5861411A/en not_active Expired - Lifetime
- 1996-08-22 GR GR960402226T patent/GR3020868T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
GR3020868T3 (en) | 1996-11-30 |
DK0427636T3 (da) | 1996-10-14 |
CA2029497A1 (en) | 1991-05-09 |
KR100192833B1 (ko) | 1999-06-15 |
EP0427636B1 (de) | 1996-05-29 |
CA2029497C (en) | 2002-06-04 |
US5536728A (en) | 1996-07-16 |
US5861411A (en) | 1999-01-19 |
KR910009667A (ko) | 1991-06-28 |
DE69027180T2 (de) | 1997-01-09 |
EP0427636A2 (de) | 1991-05-15 |
ATE138653T1 (de) | 1996-06-15 |
ES2088998T3 (es) | 1996-10-01 |
US5397785A (en) | 1995-03-14 |
EP0427636A3 (en) | 1991-11-06 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |