DE69825147D1 - 2-amino-6-(2-substituierte-4-phenoxy)-substituierte-pyridine - Google Patents

2-amino-6-(2-substituierte-4-phenoxy)-substituierte-pyridine

Info

Publication number
DE69825147D1
DE69825147D1 DE69825147T DE69825147T DE69825147D1 DE 69825147 D1 DE69825147 D1 DE 69825147D1 DE 69825147 T DE69825147 T DE 69825147T DE 69825147 T DE69825147 T DE 69825147T DE 69825147 D1 DE69825147 D1 DE 69825147D1
Authority
DE
Germany
Prior art keywords
substituted
pyridines
phenoxy
amino
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69825147T
Other languages
English (en)
Other versions
DE69825147T2 (de
Inventor
Adams Lowe
Jolanta Nowakowski
Alfred Volkmann
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Products Inc
Original Assignee
Pfizer Products Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Products Inc filed Critical Pfizer Products Inc
Publication of DE69825147D1 publication Critical patent/DE69825147D1/de
Application granted granted Critical
Publication of DE69825147T2 publication Critical patent/DE69825147T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/73—Unsubstituted amino or imino radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/08—Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
DE69825147T 1997-02-10 1998-01-29 2-amino-6-(2-substituierte-4-phenoxy)-substituierte-pyridine Expired - Fee Related DE69825147T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US3753397P 1997-02-10 1997-02-10
US37533P 1997-02-10
PCT/IB1998/000112 WO1998034919A1 (en) 1997-02-10 1998-01-29 2-amino-6-(2-substituted-4-phenoxy)-substituted-pyridines

Publications (2)

Publication Number Publication Date
DE69825147D1 true DE69825147D1 (de) 2004-08-26
DE69825147T2 DE69825147T2 (de) 2005-08-04

Family

ID=21894849

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69825147T Expired - Fee Related DE69825147T2 (de) 1997-02-10 1998-01-29 2-amino-6-(2-substituierte-4-phenoxy)-substituierte-pyridine

Country Status (44)

Country Link
US (2) US20010007873A1 (de)
EP (1) EP0958282B1 (de)
JP (1) JP3505189B2 (de)
KR (1) KR100460399B1 (de)
CN (3) CN1246848A (de)
AP (1) AP833A (de)
AR (1) AR011117A1 (de)
AT (1) ATE271544T1 (de)
AU (1) AU744313B2 (de)
BG (1) BG103633A (de)
BR (1) BR9811093A (de)
CA (1) CA2277990C (de)
CO (1) CO4920225A1 (de)
CZ (1) CZ292135B6 (de)
DE (1) DE69825147T2 (de)
DK (1) DK0958282T3 (de)
DZ (1) DZ2414A1 (de)
EA (1) EA003834B1 (de)
ES (1) ES2224354T3 (de)
GT (1) GT199800032A (de)
HN (1) HN1998000030A (de)
HR (1) HRP980069A2 (de)
HU (1) HUP0000762A3 (de)
IL (1) IL130898A0 (de)
IS (1) IS5118A (de)
MA (1) MA27676A1 (de)
MY (1) MY120976A (de)
NO (1) NO314803B1 (de)
NZ (2) NZ336623A (de)
OA (1) OA11084A (de)
PA (1) PA8446301A1 (de)
PE (1) PE58599A1 (de)
PL (1) PL335161A1 (de)
PT (1) PT958282E (de)
SI (1) SI0958282T1 (de)
SK (1) SK101199A3 (de)
TN (1) TNSN98024A1 (de)
TR (1) TR199901917T2 (de)
TW (1) TW458969B (de)
UA (1) UA64740C2 (de)
UY (1) UY24881A1 (de)
WO (1) WO1998034919A1 (de)
YU (1) YU35699A (de)
ZA (1) ZA981017B (de)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20010049379A1 (en) 1997-08-27 2001-12-06 Lowe John Adams 2-aminopyridines containing fused ring substituents
ES2235475T3 (es) * 1998-06-03 2005-07-01 Pfizer Products Inc. 2-aminopiridinas que contienen sustituyentes de anillos condensados como inhibidores de oxido nitrico sintasa.
EE200100084A (xx) * 1998-08-11 2002-08-15 Pfizer Products Inc. NOS inhibiitorite uued farmatseutilised kasutusv�imalused
SE9803710L (sv) 1998-09-25 2000-03-26 A & Science Invest Ab Användning av vissa substanser för behandling av nervrotsskador
US7115557B2 (en) 1998-09-25 2006-10-03 Sciaticon Ab Use of certain drugs for treating nerve root injury
KR20010114213A (ko) 1999-02-25 2001-12-31 실버스타인 아써 에이. 접합 고리 치환기를 함유한 2-아미노피리딘
FR2812635B1 (fr) * 2000-08-01 2002-10-11 Aventis Pharma Sa Nouveaux composes heterocycliques, preparation et utilisation comme medicaments notamment comme anti- bacteriens
GB0019006D0 (en) * 2000-08-04 2000-09-20 Astrazeneca Ab Novel compounds
US20030045449A1 (en) * 2001-08-15 2003-03-06 Pfizer, Inc. Pharmaceutical combinations for the treatment of neurodegenerative diseases
US20030232739A1 (en) * 2001-08-15 2003-12-18 Pfizer Inc. Pharmaceutical combinations comprising a NOS inhibitor and an NMDA receptor antagonist
DOP2002000467A (es) * 2001-10-10 2003-04-15 Pfizer Prod Inc 2-amino-6 (fenilo sustituido en las posiciones 2,4,5)-piridinas
US6803470B2 (en) 2001-10-10 2004-10-12 Pfizer Inc 2-amino-6-(2,4,5-substituted-phenyl)-pyridines
US7045652B2 (en) * 2002-07-03 2006-05-16 Pfizer Inc Processes for preparing substituted aryl boronic acids
US20040092741A1 (en) * 2002-11-08 2004-05-13 Pfizer Inc Substituted pyridines via boronic acid coupling
WO2005007627A1 (ja) * 2003-07-18 2005-01-27 Nihon Nohyaku Co., Ltd. フェニルピリジン誘導体、その中間体及びこれを有効成分とする除草剤
CA2598484A1 (en) * 2005-02-21 2006-08-24 Proximagen Ltd. Inhibition or treatment of dyskinesia
GB0607196D0 (en) * 2006-04-11 2006-05-17 Prosidion Ltd G-protein coupled receptor agonists
WO2008080938A1 (en) * 2006-12-28 2008-07-10 Basf Se Use 2-substituted pyridines for cancer treatment
UA105182C2 (ru) 2008-07-03 2014-04-25 Ньюрексон, Інк. Бензоксазины, бензотиазины и родственные соединения, которые имеют ингибирующую nos активность
CN108017603B (zh) 2013-02-28 2021-07-23 株式会社蒂奥姆生物 三环化合物及其用途
EP3066072B1 (de) * 2013-11-07 2021-11-03 The University of Kansas Biphenylamidderivate als hsp90-inhibitoren
AU2015302633B2 (en) * 2014-08-13 2020-01-16 Meiji Seika Pharma Co., Ltd. Crystalline anti-trichophyton agents and preparation process thereof
CN106265640B (zh) * 2016-08-11 2019-05-14 吉林大学 Appa在制备治疗糖尿病肾病药物中的应用
CN108069831B (zh) * 2018-01-25 2020-11-24 上海恩氟佳科技有限公司 一种合成2,3-二甲基-4-氟苯酚的方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994014780A1 (en) * 1992-12-18 1994-07-07 The Wellcome Foundation Limited Pyrimidine, pyridine, pteridinone and indazole derivatives as enzyme inhibitors
RU2136661C1 (ru) * 1993-10-21 1999-09-10 Джи Ди Сирл энд Ко. Амидинопроизводные, их применение и фармацевтическая композиция
WO1996018616A1 (en) * 1994-12-12 1996-06-20 Merck & Co., Inc. Substituted 2-aminopyridines as inhibitors of nitric oxide synthase
PT891332E (pt) * 1996-03-29 2004-07-30 Pfizer Derivados de 6-fenilpiridil-2-amina

Also Published As

Publication number Publication date
AP833A (en) 2000-05-10
TR199901917T2 (xx) 1999-12-21
CZ292135B6 (cs) 2003-08-13
JP3505189B2 (ja) 2004-03-08
US20030162765A1 (en) 2003-08-28
NO993823D0 (no) 1999-08-09
CN1246848A (zh) 2000-03-08
TW458969B (en) 2001-10-11
AU5572798A (en) 1998-08-26
PT958282E (pt) 2004-11-30
SK101199A3 (en) 2000-10-09
NZ518345A (en) 2005-02-25
PE58599A1 (es) 1999-06-12
IL130898A0 (en) 2001-01-28
DZ2414A1 (fr) 2003-01-04
ATE271544T1 (de) 2004-08-15
JP2000509408A (ja) 2000-07-25
HRP980069A2 (en) 1998-12-31
EP0958282A1 (de) 1999-11-24
TNSN98024A1 (fr) 2005-03-15
DE69825147T2 (de) 2005-08-04
EP0958282B1 (de) 2004-07-21
GT199800032A (es) 1998-02-11
CO4920225A1 (es) 2000-05-29
BR9811093A (pt) 2000-07-18
DK0958282T3 (da) 2004-11-29
SI0958282T1 (en) 2005-02-28
ES2224354T3 (es) 2005-03-01
KR20000070803A (ko) 2000-11-25
EA003834B1 (ru) 2003-10-30
HN1998000030A (es) 1998-10-22
PL335161A1 (en) 2000-04-10
UA64740C2 (uk) 2004-03-15
YU35699A (sh) 2002-06-19
MY120976A (en) 2005-12-30
NZ336623A (en) 2000-11-24
IS5118A (is) 1999-07-29
AR011117A1 (es) 2000-08-02
NO993823L (no) 1999-08-09
US20010007873A1 (en) 2001-07-12
HUP0000762A2 (hu) 2000-09-28
CA2277990C (en) 2006-08-01
CA2277990A1 (en) 1998-08-13
CN1515554A (zh) 2004-07-28
MA27676A1 (fr) 2006-01-02
CZ276999A3 (cs) 2000-05-17
NO314803B1 (no) 2003-05-26
BG103633A (bg) 2000-11-30
EA199900632A1 (ru) 2000-02-28
PA8446301A1 (es) 2000-05-24
UY24881A1 (es) 2000-12-29
CN1523015A (zh) 2004-08-25
ZA981017B (en) 1999-08-10
OA11084A (en) 2002-03-15
HUP0000762A3 (en) 2000-10-30
AU744313B2 (en) 2002-02-21
KR100460399B1 (ko) 2004-12-08
WO1998034919A1 (en) 1998-08-13

Similar Documents

Publication Publication Date Title
DE59806832D1 (de) Zementationshilfsmittel
ATA93198A (de) Fluoxetinpellets
NO20001813D0 (no) Aminosmørsyrederivater
DE69819047D1 (de) Sterilizationsindikator
DE69806057D1 (de) Schubdüsenverstelleinrichtung
ATE271544T1 (de) 2-amino-6-(2-substituierte-4-phenoxy)- substituierte-pyridine
DE69830527D1 (de) Hochdruckreinigungsdüse
DE69824811D1 (de) Propelleraxiallager
DE69816706D1 (de) Polycarbonatabmischung
DE69821927D1 (de) Rollenlager
DE69804086D1 (de) Transientbildstruktur
DE69809354D1 (de) Lichtbogenzündhilfsvorrichtung
NO993633L (no) 5-Aroylnaftalen-Derivater
ATA111897A (de) Kimme
DE69816499D1 (de) Kodemultiplexnachrichtenübertragungssystem
ATE236897T1 (de) 3-benzylpiperidine
ATA112597A (de) Snowboard - bindung
DE69808176T2 (de) Invertierungsverstärkerschaltung
DE59811562D1 (de) Brieftaubenkonstatiersystem
DE69734891D1 (de) Ausrichtvorrichtung
FI972138A0 (fi) Returtraog i bestrykningsanordning
ATA86797A (de) Verschleissschuh
DE69827113D1 (de) Kabelführung
ATA46498A (de) Kunststoffgleitbahn
FI971651A0 (fi) Spaormaskin i en elmaskin

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee