DE69801893T2 - Ölige Pflaster mit NA-Diclofenac zur äusseren Anwendung - Google Patents

Ölige Pflaster mit NA-Diclofenac zur äusseren Anwendung

Info

Publication number
DE69801893T2
DE69801893T2 DE69801893T DE69801893T DE69801893T2 DE 69801893 T2 DE69801893 T2 DE 69801893T2 DE 69801893 T DE69801893 T DE 69801893T DE 69801893 T DE69801893 T DE 69801893T DE 69801893 T2 DE69801893 T2 DE 69801893T2
Authority
DE
Germany
Prior art keywords
plasters
diclofenac
oily
external use
external
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69801893T
Other languages
English (en)
Other versions
DE69801893D1 (de
Inventor
Toshikuni Kawaji
Masahiro Yamaji
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Teikoku Seiyaku Co Ltd
Original Assignee
Teikoku Seiyaku Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Teikoku Seiyaku Co Ltd filed Critical Teikoku Seiyaku Co Ltd
Application granted granted Critical
Publication of DE69801893D1 publication Critical patent/DE69801893D1/de
Publication of DE69801893T2 publication Critical patent/DE69801893T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/196—Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7076—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising ingredients of undetermined constitution or reaction products thereof, e.g. rosin or other plant resins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Botany (AREA)
  • Pain & Pain Management (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
DE69801893T 1997-07-18 1998-07-14 Ölige Pflaster mit NA-Diclofenac zur äusseren Anwendung Expired - Lifetime DE69801893T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP19375997A JP4181232B2 (ja) 1997-07-18 1997-07-18 ジクロフェナクナトリウム含有油性外用貼付製剤
PCT/JP1998/003135 WO1999003461A1 (fr) 1997-07-18 1998-07-14 Timbres huileux pour usage externe contenant du diclofenac sodium

Publications (2)

Publication Number Publication Date
DE69801893D1 DE69801893D1 (de) 2001-11-08
DE69801893T2 true DE69801893T2 (de) 2002-04-25

Family

ID=16313344

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69801893T Expired - Lifetime DE69801893T2 (de) 1997-07-18 1998-07-14 Ölige Pflaster mit NA-Diclofenac zur äusseren Anwendung

Country Status (11)

Country Link
US (1) US6262121B1 (de)
EP (1) EP0950408B1 (de)
JP (1) JP4181232B2 (de)
KR (1) KR100540821B1 (de)
AU (1) AU708584B2 (de)
CA (1) CA2265893C (de)
DE (1) DE69801893T2 (de)
DK (1) DK0950408T3 (de)
ES (1) ES2167910T3 (de)
HK (1) HK1020675A1 (de)
WO (1) WO1999003461A1 (de)

Families Citing this family (34)

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CA2379147C (en) * 1999-07-15 2009-09-01 Hisamitsu Pharmaceutical Co., Inc. Percutaneously absorbable preparations
KR100363476B1 (ko) * 2000-06-27 2002-12-05 대신제약주식회사 디크로 페낙 또는 그의 염들을 함유한 경피투과용 경고제
TWI290464B (en) * 2000-09-01 2007-12-01 Novartis Consumer Health Sa Treatment of burns
PL360999A1 (en) * 2000-09-18 2004-09-20 Laboratoires Fournier Sa Patch comprising diclofenac
JP2004529953A (ja) * 2001-05-11 2004-09-30 エラン コーポレーシヨン ピーエルシー 浸透促進剤としてのイソステアリン酸塩
ATE547095T1 (de) * 2001-05-11 2012-03-15 Isis Pharmaceuticals Inc Antisense-permeationsverstärker
JP4865958B2 (ja) * 2001-05-23 2012-02-01 株式会社トクホン 鎮痛抗炎症局所作用型の貼付剤
US20060088579A1 (en) * 2002-02-07 2006-04-27 Shastri Venkatram P Transdermal drug delivery systems
EP1477164B1 (de) 2002-02-19 2012-06-06 Hisamitsu Pharmaceutical Co. Inc. Perkutanes pflaster vom absorptionstyp
WO2004082672A1 (ja) * 2003-03-18 2004-09-30 Hisamitsu Pharmaceutical Co., Inc. 非ステロイド系消炎鎮痛剤含有貼付剤
JP4541686B2 (ja) * 2003-11-19 2010-09-08 株式会社 メドレックス 非ステロイド系消炎鎮痛剤を含有するテープ剤
WO2005102306A1 (ja) * 2004-04-23 2005-11-03 Hisamitsu Pharmaceutical Co., Inc. 消炎鎮痛貼付剤
KR100663163B1 (ko) * 2005-10-24 2007-01-02 (주)아모레퍼시픽 비스테로이드성 소염진통제를 함유하는 경피 투여 제제
GB0524958D0 (en) * 2005-12-07 2006-01-18 Pharmakodex Ltd Transdermal administration of active agents
US7704977B2 (en) 2006-04-07 2010-04-27 Merrion Research Iii Limited Solid oral dosage form containing an enhancer
US20090221703A1 (en) 2006-07-09 2009-09-03 Chongxi Yu High penetration composition and uses thereof
US20090238763A1 (en) * 2006-07-09 2009-09-24 Chongxi Yu High penetration compositions and uses thereof
ES2472545T3 (es) 2006-07-25 2014-07-01 Techfields Biochem Co. Ltd Profármacos de diclofenaco solubles en agua con carga positiva y con una tasa de penetración en piel muy rápida
JP5075378B2 (ja) * 2006-09-08 2012-11-21 久光製薬株式会社 貼付剤製品
US9371284B2 (en) 2007-06-04 2016-06-21 Techfields Pharma Co., Ltd. Pro-drugs of NSAIAS with very high skin and membranes penetration rates and their new medicinal uses
WO2009048027A1 (ja) * 2007-10-09 2009-04-16 Arkray, Inc. 免疫関連遺伝子の多型の検出用プローブおよびその用途
JP2011519928A (ja) 2008-05-07 2011-07-14 メリオン・リサーチ・Ｉｉｉ・リミテッド ペプチドの組成物及びその調製方法
KR20230085223A (ko) 2008-12-04 2023-06-13 충시 위 고투과력을 가진 조성물 및 이의 적용
WO2010087947A2 (en) * 2009-01-30 2010-08-05 Kydes Pharmaceuticals, Llc Transdermal delivery of diclofenac, carbamazepine and benzydamine
US9089484B2 (en) 2010-03-26 2015-07-28 Merrion Research Iii Limited Pharmaceutical compositions of selective factor Xa inhibitors for oral administration
ITMI20111355A1 (it) 2011-07-20 2013-01-21 Epifarma Srl Cerotto transdermico contenente diclofenac e tiocolchicoside
US9783574B2 (en) 2011-08-18 2017-10-10 Otago Innovation Limited Cardiovascular therapeutics
EP2865378B1 (de) * 2012-06-20 2017-11-01 Hisamitsu Pharmaceutical Co., Inc. Hautpflaster
EP3250191B1 (de) 2015-01-29 2024-01-17 Novo Nordisk A/S Tabletten mit glp-1-agonisten und magensaftresistentem überzug
JP7117748B2 (ja) * 2017-09-22 2022-08-15 帝國製薬株式会社 貼付剤
JP6744511B1 (ja) * 2020-02-12 2020-08-19 久光製薬株式会社 ジクロフェナクナトリウム含有貼付剤
JP6761553B1 (ja) * 2020-02-12 2020-09-23 久光製薬株式会社 ジクロフェナクナトリウム含有貼付剤
IT202000011686A1 (it) * 2020-05-20 2021-11-20 Fidia Farm Spa Cerotto medicato a lento rilascio
US11872320B2 (en) 2021-02-25 2024-01-16 Hisamitsu Pharmaceutical Co., Inc. Method for treating osteoarthritis

Family Cites Families (26)

* Cited by examiner, † Cited by third party
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JPS54138124A (en) 1978-04-19 1979-10-26 Hisamitsu Pharmaceut Co Inc Novel plaster and its preparation
JPS55133310A (en) 1979-04-03 1980-10-17 Hisamitsu Pharmaceut Co Inc Novel paste tape and its production
GB2045618B (en) * 1979-04-03 1983-05-11 Hisamitsu Pharmaceutical Co Adhesive plaster
JPS5933211A (ja) 1982-08-20 1984-02-23 Sato Seiyaku Kk 油性軟膏
JPS5976013A (ja) 1982-10-23 1984-04-28 Toko Yakuhin Kogyo Kk 外用ゲル製剤
JPS6160608A (ja) 1984-08-30 1986-03-28 Taisho Pharmaceut Co Ltd ジクロフェナック湿布剤
JPH0774145B2 (ja) * 1986-12-15 1995-08-09 株式会社資生堂 結晶性薬物含有乳化組成物
JPH07116026B2 (ja) 1987-07-07 1995-12-13 株式会社資生堂 ジクロフェナックナトリウム含有乳化外用剤
JPH0749042B2 (ja) 1988-05-25 1995-05-31 久光製薬株式会社 温熱貼付剤
JPH0736835B2 (ja) 1988-05-25 1995-04-26 久光製薬株式会社 粘着剤組成物
DE69021511T2 (de) * 1989-11-14 1996-11-21 Beta Pharm Co Entzündungshemmende Arzneimittel zur äusserlichen Anwendung.
JP3100408B2 (ja) * 1991-03-26 2000-10-16 株式会社資生堂 ジクロフェナックナトリウム含有皮膚外用製剤
JP3541849B2 (ja) 1991-04-19 2004-07-14 久光製薬株式会社 消炎鎮痛貼付剤
JP2971224B2 (ja) 1991-11-30 1999-11-02 久光製薬株式会社 エストラジオール経皮吸収貼付剤
JPH0656660A (ja) 1992-07-31 1994-03-01 Nippon Saafuakutanto Kogyo Kk ジクロフェナクナトリウム含有貼付剤
JPH06321771A (ja) 1992-07-31 1994-11-22 Tanabe Seiyaku Co Ltd 経皮投与用基剤
JPH06219940A (ja) * 1993-01-27 1994-08-09 Shiseido Co Ltd 貼付剤
AU676562B2 (en) * 1993-05-19 1997-03-13 Hisamitsu Pharmaceutical Co., Inc. Solubilizing agent and external preparation containing the same
JPH0789853A (ja) 1993-09-24 1995-04-04 Shiseido Co Ltd 貼付剤
JP3054009B2 (ja) 1993-12-14 2000-06-19 帝人株式会社 プラスター
JP3782834B2 (ja) 1994-10-26 2006-06-07 株式会社トクホン 鎮痛抗炎症貼付剤
JP3693696B2 (ja) 1994-12-15 2005-09-07 久光製薬株式会社 ケトチフェン含有経皮投与製剤
JPH08319234A (ja) 1995-05-24 1996-12-03 Yuutoku Yakuhin Kogyo Kk 経皮吸収型消炎鎮痛貼付剤
JPH09208463A (ja) 1996-02-07 1997-08-12 Tsumura & Co 経皮吸収性に優れた消炎鎮痛組成物
KR19990082208A (ko) * 1996-02-07 1999-11-25 오이시 고지 디클로페낙 나트륨의 투명 수용액 및 이를 이용한 의약 조성물
JPH10147521A (ja) 1996-09-18 1998-06-02 Yuutoku Yakuhin Kogyo Kk 持続性疼痛緩和用貼付剤

Also Published As

Publication number Publication date
AU708584B2 (en) 1999-08-05
KR100540821B1 (ko) 2006-01-12
EP0950408A4 (de) 1999-12-01
CA2265893C (en) 2008-02-19
HK1020675A1 (en) 2000-05-19
KR20000068581A (ko) 2000-11-25
DK0950408T3 (da) 2002-01-28
ES2167910T3 (es) 2002-05-16
EP0950408A1 (de) 1999-10-20
JP4181232B2 (ja) 2008-11-12
EP0950408B1 (de) 2001-10-04
WO1999003461A1 (fr) 1999-01-28
CA2265893A1 (en) 1999-01-28
DE69801893D1 (de) 2001-11-08
JPH1135458A (ja) 1999-02-09
AU8129598A (en) 1999-02-10
US6262121B1 (en) 2001-07-17

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Legal Events

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