DE69434926D1 - Menschlicher gewebsinhibitor von metalloproteinase-4 - Google Patents

Menschlicher gewebsinhibitor von metalloproteinase-4

Info

Publication number
DE69434926D1
DE69434926D1 DE69434926T DE69434926T DE69434926D1 DE 69434926 D1 DE69434926 D1 DE 69434926D1 DE 69434926 T DE69434926 T DE 69434926T DE 69434926 T DE69434926 T DE 69434926T DE 69434926 D1 DE69434926 D1 DE 69434926D1
Authority
DE
Germany
Prior art keywords
polypeptide
disclosed
tissue inhibitor
human tissue
metaloproteinase
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69434926T
Other languages
English (en)
Other versions
DE69434926T2 (de
Inventor
John M Greene
Craig A Rosen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Human Genome Sciences Inc
Original Assignee
Human Genome Sciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22243411&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69434926(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Human Genome Sciences Inc filed Critical Human Genome Sciences Inc
Publication of DE69434926D1 publication Critical patent/DE69434926D1/de
Application granted granted Critical
Publication of DE69434926T2 publication Critical patent/DE69434926T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/8146—Metalloprotease (E.C. 3.4.24) inhibitors, e.g. tissue inhibitor of metallo proteinase, TIMP
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00—Uses of viruses
    • C12N2799/02—Uses of viruses as vector
    • C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
    • C12N2799/026—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a baculovirus
DE69434926T 1994-12-13 1994-12-13 Menschlicher gewebsinhibitor von metalloproteinase-4 Expired - Fee Related DE69434926T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US1994/014498 WO1996018725A1 (en) 1994-12-13 1994-12-13 Human tissue inhibitor of metalloproteinase-4

Publications (2)

Publication Number Publication Date
DE69434926D1 true DE69434926D1 (de) 2007-04-05
DE69434926T2 DE69434926T2 (de) 2008-03-06

Family

ID=22243411

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69434926T Expired - Fee Related DE69434926T2 (de) 1994-12-13 1994-12-13 Menschlicher gewebsinhibitor von metalloproteinase-4

Country Status (9)

Country Link
US (4) US6300310B1 (de)
EP (1) EP0815202B1 (de)
JP (1) JPH10510986A (de)
AT (1) ATE354638T1 (de)
AU (1) AU708829B2 (de)
DE (1) DE69434926T2 (de)
ES (1) ES2281898T3 (de)
NZ (1) NZ279963A (de)
WO (1) WO1996018725A1 (de)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH10510986A (ja) 1994-12-13 1998-10-27 ヒューマン ジノーム サイエンシーズ， インコーポレイテッド メタロプロテイナーゼ−４のヒト組織インヒビター
US6544761B2 (en) 1994-12-13 2003-04-08 Human Genome Sciences, Inc. Human tissue inhibitor of metalloproteinase-4
US5643752A (en) * 1996-01-18 1997-07-01 Incyte Pharmaceuticals, Inc. Tissue inhibitor of metalloproteinases
US7129061B1 (en) * 1996-08-07 2006-10-31 Biogen Idec Ma Inc. Tumor necrosis factor related ligand
WO2000032175A2 (en) * 1998-12-02 2000-06-08 Pfizer Products Inc. METHODS AND COMPOSITIONS FOR RESTORING CONFORMATIONAL STABILITY OF A PROTEIN OF THE p53 FAMILY
EA004590B1 (ru) 1999-01-15 2004-06-24 Байоджен, Инк. Способ блокировки развития, или снижения тяжести, или проявлений заболевания "трасплантат против хозяина"
AU3735900A (en) * 1999-03-11 2000-09-28 Human Genome Sciences, Inc. Methods of treatment and prevention of restenosis
CA2385488C (en) * 1999-09-24 2015-07-07 Nicholas F. Franano Systems and methods for opening obstructed biological conduits
US7063838B1 (en) 1999-09-24 2006-06-20 Proteon Therapeutics Llc Methods for treating an artery or vein in a human subject
US7632494B2 (en) 1999-09-24 2009-12-15 Proteon Therapeutics, Inc. Methods for enlarging the diameter of a biological conduit in a human subject
US7115665B1 (en) 2000-11-16 2006-10-03 Onocozyme Pharma, Inc. Inhibitors of endo-exonuclease activity for treating cancer
AU5951901A (en) * 2000-05-08 2001-11-20 Biogen Inc Method for promoting neovascularization
US20020198207A1 (en) * 2000-05-18 2002-12-26 Kath John Charles Novel Hexanoic acid derivatives
US7208151B2 (en) * 2001-09-12 2007-04-24 Biogen Idec Ma Inc. Tweak receptor agonists as anti-angiogenic agents
US7094754B2 (en) 2001-08-16 2006-08-22 Kimberly-Clark Worldwide, Inc. Anti-aging and wound healing compounds
US7186693B2 (en) 2001-08-16 2007-03-06 Kimberly - Clark Worldwide, Inc. Metalloproteinase inhibitors for wound healing
US7071164B2 (en) 2001-08-16 2006-07-04 Kimberly-Clark Worldwide, Inc. Anti-cancer and wound healing compounds
US6906036B2 (en) 2001-08-16 2005-06-14 Kimberly-Clark Worldwide, Inc. Anti-aging and wound healing compounds
NZ548701A (en) 2002-04-09 2008-03-28 Biogen Idec Inc Methods for treating tweak-related conditions
US7148194B2 (en) 2002-12-30 2006-12-12 Kimberly-Clark Worldwide, Inc. Method to increase fibronectin
US7189700B2 (en) 2003-06-20 2007-03-13 Kimberly-Clark Worldwide, Inc. Anti-chrondrosarcoma compounds
EP1859277A4 (de) 2005-02-17 2010-03-17 Biogen Idec Inc Behandlung neurologischer störungen
JP5339901B2 (ja) 2005-05-10 2013-11-13 バイオジェン・アイデック・エムエイ・インコーポレイテッド 炎症傷害の処置および評価
WO2006138219A2 (en) 2005-06-13 2006-12-28 Biogen Idec Ma Inc. Methods of diagnosis / prognosis of inflammatory conditions
KR101143891B1 (ko) 2009-12-29 2012-05-11 한국기초과학지원연구원 단백질의 비정상적인 당쇄화를 이용하는 암진단 마커
US11851475B2 (en) * 2018-01-03 2023-12-26 Xi'an Jiaotong-Liverpool University Membrane-type metalloprotease inhibitory protein and pharmaceutical and pharmaceutical composition containing same, and respective uses thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE219776T1 (de) * 1989-03-21 2002-07-15 Us Secretary United States Dep Matrizenmetalloproteinase-inhibitor-peptide
JP2877509B2 (ja) * 1989-05-19 1999-03-31 アムジエン・インコーポレーテツド メタロプロテイナーゼ阻害剤
JPH10510986A (ja) 1994-12-13 1998-10-27 ヒューマン ジノーム サイエンシーズ， インコーポレイテッド メタロプロテイナーゼ−４のヒト組織インヒビター
US5643752A (en) 1996-01-18 1997-07-01 Incyte Pharmaceuticals, Inc. Tissue inhibitor of metalloproteinases

Also Published As

Publication number Publication date
EP0815202A1 (de) 1998-01-07
EP0815202B1 (de) 2007-02-21
AU1724795A (en) 1996-07-03
US6448042B1 (en) 2002-09-10
NZ279963A (en) 1998-10-28
AU708829B2 (en) 1999-08-12
US20020115187A1 (en) 2002-08-22
WO1996018725A1 (en) 1996-06-20
US6828424B2 (en) 2004-12-07
JPH10510986A (ja) 1998-10-27
US6300310B1 (en) 2001-10-09
DE69434926T2 (de) 2008-03-06
EP0815202A4 (de) 2002-10-16
ES2281898T3 (es) 2007-10-01
US6391853B1 (en) 2002-05-21
ATE354638T1 (de) 2007-03-15

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee