ATE354638T1 - Menschlicher gewebsinhibitor von metalloproteinase-4 - Google Patents

Menschlicher gewebsinhibitor von metalloproteinase-4

Info

Publication number
ATE354638T1
ATE354638T1 AT95909203T AT95909203T ATE354638T1 AT E354638 T1 ATE354638 T1 AT E354638T1 AT 95909203 T AT95909203 T AT 95909203T AT 95909203 T AT95909203 T AT 95909203T AT E354638 T1 ATE354638 T1 AT E354638T1
Authority
AT
Austria
Prior art keywords
polypeptide
disclosed
tissue inhibitor
human tissue
metalloproteinase
Prior art date
Application number
AT95909203T
Other languages
English (en)
Inventor
John M Greene
Craig A Rosen
Original Assignee
Human Genome Sciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22243411&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE354638(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Human Genome Sciences Inc filed Critical Human Genome Sciences Inc
Application granted granted Critical
Publication of ATE354638T1 publication Critical patent/ATE354638T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/8146—Metalloprotease (E.C. 3.4.24) inhibitors, e.g. tissue inhibitor of metallo proteinase, TIMP
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00—Uses of viruses
    • C12N2799/02—Uses of viruses as vector
    • C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
    • C12N2799/026—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a baculovirus
AT95909203T 1994-12-13 1994-12-13 Menschlicher gewebsinhibitor von metalloproteinase-4 ATE354638T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US1994/014498 WO1996018725A1 (en) 1994-12-13 1994-12-13 Human tissue inhibitor of metalloproteinase-4

Publications (1)

Publication Number Publication Date
ATE354638T1 true ATE354638T1 (de) 2007-03-15

Family

ID=22243411

Family Applications (1)

Application Number Title Priority Date Filing Date
AT95909203T ATE354638T1 (de) 1994-12-13 1994-12-13 Menschlicher gewebsinhibitor von metalloproteinase-4

Country Status (9)

Country Link
US (4) US6300310B1 (de)
EP (1) EP0815202B1 (de)
JP (1) JPH10510986A (de)
AT (1) ATE354638T1 (de)
AU (1) AU708829B2 (de)
DE (1) DE69434926T2 (de)
ES (1) ES2281898T3 (de)
NZ (1) NZ279963A (de)
WO (1) WO1996018725A1 (de)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69434926T2 (de) 1994-12-13 2008-03-06 Human Genome Sciences, Inc. Menschlicher gewebsinhibitor von metalloproteinase-4
US6544761B2 (en) 1994-12-13 2003-04-08 Human Genome Sciences, Inc. Human tissue inhibitor of metalloproteinase-4
US5643752A (en) * 1996-01-18 1997-07-01 Incyte Pharmaceuticals, Inc. Tissue inhibitor of metalloproteinases
US7129061B1 (en) * 1996-08-07 2006-10-31 Biogen Idec Ma Inc. Tumor necrosis factor related ligand
OA11722A (en) * 1998-12-02 2005-01-25 Pfizer Prod Inc Methods and compositions for restoring conformational stability of a protein of the p53 family.
KR20010102978A (ko) 1999-01-15 2001-11-17 아스트루 마이클 제이 면역 질환 치료를 위한 트위크 길항약 및 트위크 수용체길항약 및 이들의 용도
WO2000053210A1 (en) * 1999-03-11 2000-09-14 Human Genome Sciences, Inc. Methods of treatment and prevention of restenosis
DK2363142T3 (en) * 1999-09-24 2015-04-20 Proteon Therapeutics Inc Elastase for opening the closed biological channels
US7632494B2 (en) 1999-09-24 2009-12-15 Proteon Therapeutics, Inc. Methods for enlarging the diameter of a biological conduit in a human subject
US7063838B1 (en) 1999-09-24 2006-06-20 Proteon Therapeutics Llc Methods for treating an artery or vein in a human subject
US7115665B1 (en) 2000-11-16 2006-10-03 Onocozyme Pharma, Inc. Inhibitors of endo-exonuclease activity for treating cancer
AU5951901A (en) * 2000-05-08 2001-11-20 Biogen Inc Method for promoting neovascularization
US20020198207A1 (en) * 2000-05-18 2002-12-26 Kath John Charles Novel Hexanoic acid derivatives
US7208151B2 (en) 2001-09-12 2007-04-24 Biogen Idec Ma Inc. Tweak receptor agonists as anti-angiogenic agents
US7094754B2 (en) 2001-08-16 2006-08-22 Kimberly-Clark Worldwide, Inc. Anti-aging and wound healing compounds
US7071164B2 (en) 2001-08-16 2006-07-04 Kimberly-Clark Worldwide, Inc. Anti-cancer and wound healing compounds
US7186693B2 (en) 2001-08-16 2007-03-06 Kimberly - Clark Worldwide, Inc. Metalloproteinase inhibitors for wound healing
US6906036B2 (en) 2001-08-16 2005-06-14 Kimberly-Clark Worldwide, Inc. Anti-aging and wound healing compounds
SI1997512T1 (sl) 2002-04-09 2014-03-31 Biogen Idec Ma Inc. Postopki za zdravljenje stanj, povezanih s TWEAK-om
US7148194B2 (en) 2002-12-30 2006-12-12 Kimberly-Clark Worldwide, Inc. Method to increase fibronectin
US7189700B2 (en) 2003-06-20 2007-03-13 Kimberly-Clark Worldwide, Inc. Anti-chrondrosarcoma compounds
US20090124993A1 (en) 2005-02-17 2009-05-14 Burkly Linda C Treating neurological disorders
WO2006122187A2 (en) 2005-05-10 2006-11-16 Biogen Idec Ma Inc. Treating and evaluating inflammatory disorders
WO2006138219A2 (en) 2005-06-13 2006-12-28 Biogen Idec Ma Inc. Methods of diagnosis / prognosis of inflammatory conditions
KR101143891B1 (ko) 2009-12-29 2012-05-11 한국기초과학지원연구원 단백질의 비정상적인 당쇄화를 이용하는 암진단 마커
WO2019134526A1 (zh) * 2018-01-03 2019-07-11 西交利物浦大学 膜型金属蛋白酶抑制蛋白和包含其的药物和药物组合物及各自的用途

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69033982T2 (de) * 1989-03-21 2002-10-24 Us Health Matrizenmetalloproteinase-inhibitor-peptide
AU648505B2 (en) * 1989-05-19 1994-04-28 Amgen, Inc. Metalloproteinase inhibitor
DE69434926T2 (de) 1994-12-13 2008-03-06 Human Genome Sciences, Inc. Menschlicher gewebsinhibitor von metalloproteinase-4
US5643752A (en) * 1996-01-18 1997-07-01 Incyte Pharmaceuticals, Inc. Tissue inhibitor of metalloproteinases

Also Published As

Publication number Publication date
US6300310B1 (en) 2001-10-09
WO1996018725A1 (en) 1996-06-20
DE69434926D1 (de) 2007-04-05
ES2281898T3 (es) 2007-10-01
AU708829B2 (en) 1999-08-12
DE69434926T2 (de) 2008-03-06
EP0815202A1 (de) 1998-01-07
US6828424B2 (en) 2004-12-07
AU1724795A (en) 1996-07-03
EP0815202B1 (de) 2007-02-21
JPH10510986A (ja) 1998-10-27
US20020115187A1 (en) 2002-08-22
NZ279963A (en) 1998-10-28
EP0815202A4 (de) 2002-10-16
US6391853B1 (en) 2002-05-21
US6448042B1 (en) 2002-09-10

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