DE69418248D1 - Optisches Laser-Abtastsystem mit Axikon - Google Patents

Optisches Laser-Abtastsystem mit Axikon

Info

Publication number
DE69418248D1
DE69418248D1 DE69418248T DE69418248T DE69418248D1 DE 69418248 D1 DE69418248 D1 DE 69418248D1 DE 69418248 T DE69418248 T DE 69418248T DE 69418248 T DE69418248 T DE 69418248T DE 69418248 D1 DE69418248 D1 DE 69418248D1
Authority
DE
Germany
Prior art keywords
axikon
laser scanning
scanning system
optical laser
optical
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69418248T
Other languages
English (en)
Other versions
DE69418248T2 (de
Inventor
Koji Ichie
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hamamatsu Photonics KK
Original Assignee
Hamamatsu Photonics KK
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hamamatsu Photonics KK filed Critical Hamamatsu Photonics KK
Application granted granted Critical
Publication of DE69418248D1 publication Critical patent/DE69418248D1/de
Publication of DE69418248T2 publication Critical patent/DE69418248T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B27/00—Optical systems or apparatus not provided for by any of the groups G02B1/00 - G02B26/00, G02B30/00
    • G02B27/09—Beam shaping, e.g. changing the cross-sectional area, not otherwise provided for
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/0004—Microscopes specially adapted for specific applications
    • G02B21/002—Scanning microscopes
    • G02B21/0024—Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
    • G02B21/0032—Optical details of illumination, e.g. light-sources, pinholes, beam splitters, slits, fibers
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/0004—Microscopes specially adapted for specific applications
    • G02B21/002—Scanning microscopes
    • G02B21/0024—Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
    • G02B21/0052—Optical details of the image generation
    • G02B21/0072—Optical details of the image generation details concerning resolution or correction, including general design of CSOM objectives
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/0004—Microscopes specially adapted for specific applications
    • G02B21/002—Scanning microscopes
    • G02B21/0024—Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
    • G02B21/0052—Optical details of the image generation
    • G02B21/0076—Optical details of the image generation arrangements using fluorescence or luminescence
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/0004—Microscopes specially adapted for specific applications
    • G02B21/002—Scanning microscopes
    • G02B21/0024—Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
    • G02B21/008—Details of detection or image processing, including general computer control
    • G02B21/0084—Details of detection or image processing, including general computer control time-scale detection, e.g. strobed, ultra-fast, heterodyne detection
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/16—Microscopes adapted for ultraviolet illumination ; Fluorescence microscopes
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B26/00—Optical devices or arrangements for the control of light using movable or deformable optical elements
    • G02B26/08—Optical devices or arrangements for the control of light using movable or deformable optical elements for controlling the direction of light
    • G02B26/10—Scanning systems
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B27/00—Optical systems or apparatus not provided for by any of the groups G02B1/00 - G02B26/00, G02B30/00
    • G02B27/09—Beam shaping, e.g. changing the cross-sectional area, not otherwise provided for
    • G02B27/0911—Anamorphotic systems
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B27/00—Optical systems or apparatus not provided for by any of the groups G02B1/00 - G02B26/00, G02B30/00
    • G02B27/09—Beam shaping, e.g. changing the cross-sectional area, not otherwise provided for
    • G02B27/0938—Using specific optical elements
    • G02B27/095—Refractive optical elements
    • G02B27/0972—Prisms
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B5/00—Optical elements other than lenses
    • G02B5/001—Axicons, waxicons, reflaxicons

Landscapes

  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • General Engineering & Computer Science (AREA)
  • Microscoopes, Condenser (AREA)
DE69418248T 1993-06-03 1994-06-03 Optisches Laser-Abtastsystem mit Axikon Expired - Fee Related DE69418248T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP13365993 1993-06-03
JP9155194 1994-04-28

Publications (2)

Publication Number Publication Date
DE69418248D1 true DE69418248D1 (de) 1999-06-10
DE69418248T2 DE69418248T2 (de) 1999-10-14

Family

ID=26432986

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69418248T Expired - Fee Related DE69418248T2 (de) 1993-06-03 1994-06-03 Optisches Laser-Abtastsystem mit Axikon

Country Status (3)

Country Link
US (2) US5583342A (de)
EP (1) EP0627643B1 (de)
DE (1) DE69418248T2 (de)

Families Citing this family (245)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5631734A (en) 1994-02-10 1997-05-20 Affymetrix, Inc. Method and apparatus for detection of fluorescently labeled materials
US20030017081A1 (en) * 1994-02-10 2003-01-23 Affymetrix, Inc. Method and apparatus for imaging a sample on a device
US6090555A (en) * 1997-12-11 2000-07-18 Affymetrix, Inc. Scanned image alignment systems and methods
US6741344B1 (en) 1994-02-10 2004-05-25 Affymetrix, Inc. Method and apparatus for detection of fluorescently labeled materials
EP0687956B2 (de) * 1994-06-17 2005-11-23 Carl Zeiss SMT AG Beleuchtungseinrichtung
EP0902885A4 (de) 1996-05-16 2006-09-27 Affymetrix Inc System und verfahren zur erkennung markierter materialien
US20060095097A1 (en) * 1996-10-30 2006-05-04 Provectus Devicetech, Inc. Treatment of pigmented tissue using optical energy
US7036516B1 (en) * 1996-10-30 2006-05-02 Xantech Pharmaceuticals, Inc. Treatment of pigmented tissues using optical energy
US6037967A (en) * 1996-12-18 2000-03-14 Etec Systems, Inc. Short wavelength pulsed laser scanner
EP1017987B1 (de) 1997-01-31 2005-06-15 The Horticulture And Food Research Institute Of New Zealand Limited Optische vorrichtung und methode
US6771417B1 (en) * 1997-08-01 2004-08-03 Carl Zeiss Jena Gmbh Applications of adaptive optics in microscopy
US6466040B1 (en) * 1997-08-01 2002-10-15 Carl Zeiss Jena Gmbh Three dimensional optical beam induced current (3-D-OBIC)
US6149867A (en) 1997-12-31 2000-11-21 Xy, Inc. Sheath fluids and collection systems for sex-specific cytometer sorting of sperm
GB2349033B (en) 1998-01-27 2002-06-26 Wisconsin Alumni Res Found Signal enhancement for fluorescence microscopy
US6855941B1 (en) * 1998-03-11 2005-02-15 Olympus Optical Co., Ltd. Laser microscope
JP3350442B2 (ja) * 1998-04-09 2002-11-25 科学技術振興事業団 顕微鏡システム
DE19816487A1 (de) 1998-04-14 1999-10-21 Bodenseewerk Perkin Elmer Co Vorrichtung zum Nachweis eines Fluoreszenzfarbstoffs
EP1917974B1 (de) 1998-07-30 2010-11-17 Xy, Llc Pferdesystem für die künstliche Befruchtung ohne chirurgischen Eingriff
IL133889A (en) 2000-01-05 2007-03-08 Orbotech Ltd Pulse light pattern writer
CN1310871A (zh) 1998-08-20 2001-08-29 奥宝科技有限公司 激光重复率放大器
US6246046B1 (en) * 1999-01-21 2001-06-12 University Of Pittsburgh Method and apparatus for electronically controlled scanning of micro-area devices
DE19908883A1 (de) 1999-03-02 2000-09-07 Rainer Heintzmann Verfahren zur Erhöhung der Auflösung optischer Abbildung
US6137632A (en) * 1999-04-19 2000-10-24 Iomega Corporation Method and apparatus for lossless beam shaping to obtain high-contrast imaging in photon tunneling methods
DE19923822A1 (de) * 1999-05-19 2000-11-23 Zeiss Carl Jena Gmbh Scannende Anordnung, vorzugsweise zur Erfassung von Fluoreszenzlicht
US6548796B1 (en) * 1999-06-23 2003-04-15 Regents Of The University Of Minnesota Confocal macroscope
US6403332B1 (en) * 1999-07-30 2002-06-11 California Institute Of Technology System and method for monitoring cellular activity
US7024316B1 (en) * 1999-10-21 2006-04-04 Dakocytomation Colorado, Inc. Transiently dynamic flow cytometer analysis system
US7208265B1 (en) 1999-11-24 2007-04-24 Xy, Inc. Method of cryopreserving selected sperm cells
DE10003570A1 (de) * 2000-01-27 2001-08-02 Leica Microsystems Mikroskop-Aufbau
DE10024135B4 (de) * 2000-01-28 2004-07-08 Leica Microsystems Heidelberg Gmbh Mikroskop
DE10004233B4 (de) 2000-02-01 2005-02-17 Leica Microsystems Heidelberg Gmbh Mikroskop-Aufbau
JP2001236673A (ja) * 2000-02-17 2001-08-31 Minolta Co Ltd 光ヘッド及び光記録・再生装置
RU2393815C2 (ru) 2000-05-09 2010-07-10 Кси, Инк. Популяции сперматозоидов, несущих х-хромосому и несущих у-хромосому, с высокой степенью очистки
US6433929B1 (en) * 2000-06-12 2002-08-13 Olympus Optical Co., Ltd. Scanning optical microscope and method of acquiring image
US20040224421A1 (en) * 2000-06-15 2004-11-11 Deweerd Herman Bi-directional scanning method
GB2363857A (en) * 2000-06-23 2002-01-09 Yokogawa Electric Corp Nipkow disk confocal scanner with optical image separation system
US6687000B1 (en) 2000-06-26 2004-02-03 Wisconsin Alumni Research Foundation Photon-sorting spectroscopic microscope system
DE10044522C2 (de) * 2000-09-04 2002-08-01 Fraunhofer Ges Forschung Optische Anordnung zur Strahlführung
EP1186886A3 (de) * 2000-09-04 2004-01-07 Fuji Photo Film Co., Ltd. Verfahren zur biochemischen Analyse und dazu geeignetes Gerät
DE10046410A1 (de) * 2000-09-18 2002-03-28 Leica Microsystems Optische Anordnung zum Beleuchten von Objekten
JP4693972B2 (ja) 2000-09-29 2011-06-01 オリンパス株式会社 レーザ顕微鏡
US6625181B1 (en) 2000-10-23 2003-09-23 U.C. Laser Ltd. Method and apparatus for multi-beam laser machining
JP4241038B2 (ja) 2000-10-30 2009-03-18 ザ ジェネラル ホスピタル コーポレーション 組織分析のための光学的な方法及びシステム
US9295391B1 (en) 2000-11-10 2016-03-29 The General Hospital Corporation Spectrally encoded miniature endoscopic imaging probe
US7713687B2 (en) 2000-11-29 2010-05-11 Xy, Inc. System to separate frozen-thawed spermatozoa into x-chromosome bearing and y-chromosome bearing populations
CA2468774C (en) 2000-11-29 2015-06-30 George E. Seidel System for in-vitro fertilization with spermatozoa separated into x-chromosome and y-chromosome bearing populations
US7453486B2 (en) * 2000-12-13 2008-11-18 Orbotech Ltd Pulse light pattern writer
EP2333522A1 (de) 2001-04-30 2011-06-15 The General Hospital Corporation Verfahren und Vorrichtung zur verbesserung der Bildklarheit und Empfindlichkeit bei der optischen Kohärenz-Tomographie unter Verwendung von dynamischer Rückkopplung zur kontrolle der Fokussierungseigenschaften und der Kohärenzsteuerung
AT503309B1 (de) 2001-05-01 2011-08-15 Gen Hospital Corp Vorrichtung zur bestimmung von atherosklerotischem belag durch messung von optischen gewebeeigenschaften
US20030211009A1 (en) * 2001-05-18 2003-11-13 Buchanan Kris S. Rapid multi-material sample input system
GB0118306D0 (en) 2001-07-27 2001-09-19 Isis Innovation Method of,and apparatus for,generating a focussed light beam
US6980299B1 (en) 2001-10-16 2005-12-27 General Hospital Corporation Systems and methods for imaging a sample
US6844537B2 (en) 2001-12-31 2005-01-18 Honeywell International Inc. Method and device for measuring the velocity of a moving surface
EP1468245B1 (de) * 2002-01-11 2011-03-30 The General Hospital Corporation Vorrichtung zur OCT Bildaufnahme mit axialem Linienfokus für verbesserte Auflösung und Tiefenschärfe
US7355716B2 (en) 2002-01-24 2008-04-08 The General Hospital Corporation Apparatus and method for ranging and noise reduction of low coherence interferometry LCI and optical coherence tomography OCT signals by parallel detection of spectral bands
JP4025097B2 (ja) * 2002-03-08 2007-12-19 富士フイルム株式会社 露光装置
JP3940995B2 (ja) * 2002-04-19 2007-07-04 富士フイルム株式会社 画像読取装置
JP4595067B2 (ja) 2002-08-01 2010-12-08 エックスワイ，エルエルシー 低圧***細胞分離システム
US8486618B2 (en) 2002-08-01 2013-07-16 Xy, Llc Heterogeneous inseminate system
MXPA05001654A (es) 2002-08-15 2005-10-18 Xy Inc Citometro de flujo de alta resolucion.
DE10239955B3 (de) * 2002-08-26 2004-05-13 Carl Zeiss Smt Ag Mikroskop mit Hell- und Dunkelfeldbeleuchtung
DE10240033B4 (de) * 2002-08-28 2005-03-10 Jenoptik Automatisierungstech Anordnung zum Einbringen von Strahlungsenergie in ein Werkstück aus einem schwach absorbierenden Material
US7169548B2 (en) 2002-09-13 2007-01-30 Xy, Inc. Sperm cell processing and preservation systems
DE10259443B4 (de) * 2002-12-19 2015-01-22 Carl Zeiss Microscopy Gmbh Verfahren und Anordnung zur optischen Untersuchung und/oder Bearbeitung einer Probe
JP4185397B2 (ja) * 2002-12-25 2008-11-26 株式会社キーエンス 光学式検出器
US7761139B2 (en) 2003-01-24 2010-07-20 The General Hospital Corporation System and method for identifying tissue using low-coherence interferometry
US8054468B2 (en) 2003-01-24 2011-11-08 The General Hospital Corporation Apparatus and method for ranging and noise reduction of low coherence interferometry LCI and optical coherence tomography OCT signals by parallel detection of spectral bands
WO2004088361A2 (en) 2003-03-31 2004-10-14 The General Hospital Corporation Speckle reduction in optical coherence tomography by path length encoded angular compounding
EP2308417B1 (de) 2003-03-28 2016-03-23 Inguran, LLC Vorrichtung und Verfahren zur Bereitstellung von sortierten Partikeln
GB0308072D0 (en) * 2003-04-08 2003-05-14 Visitech Internat Ltd Fast multi-line laser confocal scanning microscope
EP1625203B1 (de) 2003-05-15 2015-04-08 Xy, Llc Effiziente sortierung haploider zellen für durchflusszytometer-systeme
KR20130138867A (ko) 2003-06-06 2013-12-19 더 제너럴 하스피탈 코포레이션 파장 동조 소스용 방법 및 장치
NO320941B1 (no) * 2003-09-12 2006-02-13 Kongsberg Defence & Aerospace Optisk transformator
EP2278287B1 (de) 2003-10-27 2016-09-07 The General Hospital Corporation Optische Abbildungsmethode und - vorrichtung mit Frequenzbereichsinterferometrie
WO2005054780A1 (en) 2003-11-28 2005-06-16 The General Hospital Corporation Method and apparatus for three-dimensional spectrally encoded imaging
CN104974983A (zh) 2004-03-29 2015-10-14 英格朗公司 用于授精的***悬浮液
KR101239250B1 (ko) 2004-05-29 2013-03-05 더 제너럴 하스피탈 코포레이션 광간섭 단층촬영 화상 진단에서 반사층을 이용한 색 분산보상을 위한 프로세스, 시스템 및 소프트웨어 배열
US7447408B2 (en) 2004-07-02 2008-11-04 The General Hospital Corproation Imaging system and related techniques
BRPI0513685A (pt) 2004-07-22 2008-05-13 Monsanto Technology Llc processo para enriquecimento de uma população de células de esperma
PL1771729T3 (pl) 2004-07-27 2016-02-29 Beckman Coulter Inc Poprawa zdolności dyskryminacji w cytometrii przepływowej przy użyciu transformacji geometrycznej
KR101332222B1 (ko) 2004-08-06 2013-11-22 더 제너럴 하스피탈 코포레이션 광간섭 단층촬영법을 이용해서 샘플 내에서 적어도 하나의 위치를 결정하는 방법, 시스템 및 그 방법을 구현하기 위한 소프트웨어가 저장되어 컴퓨터로 판독 가능한 매체
EP2272421A1 (de) 2004-08-24 2011-01-12 The General Hospital Corporation Verfahren und Vorrichtung zur Abbildung von Gefäßsegmenten
EP1793730B1 (de) 2004-08-24 2011-12-28 The General Hospital Corporation Verfahren, system und software-anordnung zur bestimmung des elastizitätsmoduls
KR101269455B1 (ko) 2004-09-10 2013-05-30 더 제너럴 하스피탈 코포레이션 광 간섭 영상화를 위한 시스템 및 방법
KR101257100B1 (ko) 2004-09-29 2013-04-22 더 제너럴 하스피탈 코포레이션 광 간섭 영상화 시스템 및 방법
WO2006050453A1 (en) 2004-11-02 2006-05-11 The General Hospital Corporation Fiber-optic rotational device, optical system and method for imaging a sample
EP1825214A1 (de) 2004-11-24 2007-08-29 The General Hospital Corporation Interferometer mit gemeinsamem pfad für endoskopische optische kohärenztomographie
JP2008521516A (ja) 2004-11-29 2008-06-26 ザ ジェネラル ホスピタル コーポレイション サンプル上の複数の地点を同時に照射し検出することによって光学画像生成を実行する構成、装置、内視鏡、カテーテル、及び方法
US7215493B2 (en) 2005-01-27 2007-05-08 Psc Scanning, Inc. Imaging system with a lens having increased light collection efficiency and a deblurring equalizer
US7499090B2 (en) * 2005-01-27 2009-03-03 Datalogic Scanning, Inc. Rolling-reset imager with optical filter
DE102005004046B4 (de) * 2005-01-28 2007-09-27 Harder. Digital Gmbh Turm Thurau Vorsatzvorrichtung für optisches Gerät sowie damit ausgestattetes Nachtsichtgerät
EP1875436B1 (de) 2005-04-28 2009-12-09 The General Hospital Corporation Bewertung von bildmerkmalen einer anatomischen struktur in optischen kohärenztomographiebildern
WO2006127967A2 (en) * 2005-05-25 2006-11-30 Massachusetts Institute Of Technology Multifocal scanning microscopy systems and methods
DE112006002099A5 (de) * 2005-05-31 2008-05-21 W.O.M. World Of Medicine Ag Verfahren und Vorrichtung zur optischen Charakterisierung von Gewebe
WO2006130797A2 (en) 2005-05-31 2006-12-07 The General Hospital Corporation Spectral encoding heterodyne interferometry techniques for imaging
US9060689B2 (en) 2005-06-01 2015-06-23 The General Hospital Corporation Apparatus, method and system for performing phase-resolved optical frequency domain imaging
EP1913332B1 (de) 2005-08-09 2010-10-13 The General Hospital Corporation Gerät und verfahren zur durchführung von polarisationsbasierter quadraturdemodulation bei optischer kohärenztomographie
US7397042B2 (en) * 2005-08-24 2008-07-08 Dr. Chip Biotechnology Incorporation Optical detection apparatus and method thereof
EP2275026A1 (de) 2005-09-29 2011-01-19 The General Hospital Corporation Anordnungen und Verfahren zur Bereitstellung multimodaler mikroskopischer Darstellung einer oder mehrerer biologischen Strukturen
JP5203951B2 (ja) 2005-10-14 2013-06-05 ザ ジェネラル ホスピタル コーポレイション スペクトル及び周波数符号化蛍光画像形成
WO2007050743A2 (en) * 2005-10-27 2007-05-03 Yale University An optical system for illumination of an evanescent field
US7796270B2 (en) 2006-01-10 2010-09-14 The General Hospital Corporation Systems and methods for generating data based on one or more spectrally-encoded endoscopy techniques
US7352789B2 (en) 2006-01-12 2008-04-01 Semiconductor Energy Laboratory Co., Ltd. Laser light irradiation apparatus and laser light irradiation method
EP2289396A3 (de) 2006-01-19 2011-04-06 The General Hospital Corporation Verfahren und Systeme zur optischen Bildgebung von epithelialen Luminalorganen durch Strahlenabtastung dieser
WO2007084903A2 (en) 2006-01-19 2007-07-26 The General Hospital Corporation Apparatus for obtaining information for a structure using spectrally-encoded endoscopy techniques and method for producing one or more optical arrangements
US8055098B2 (en) 2006-01-27 2011-11-08 Affymetrix, Inc. System, method, and product for imaging probe arrays with small feature sizes
US9445025B2 (en) 2006-01-27 2016-09-13 Affymetrix, Inc. System, method, and product for imaging probe arrays with small feature sizes
EP2659851A3 (de) 2006-02-01 2014-01-15 The General Hospital Corporation Vorrichtung zur Anwendung mehrerer elektromagnetischer Strahlungen auf einer Probe
JP5524487B2 (ja) 2006-02-01 2014-06-18 ザ ジェネラル ホスピタル コーポレイション コンフォーマルレーザ治療手順を用いてサンプルの少なくとも一部分に電磁放射を放射する方法及びシステム。
US7418169B2 (en) 2006-02-01 2008-08-26 The General Hospital Corporation Apparatus for controlling at least one of at least two sections of at least one fiber
WO2007092911A2 (en) 2006-02-08 2007-08-16 The General Hospital Corporation Methods, arrangements and systems for obtaining information associated with an anatomical sample using optical microscopy
US7982879B2 (en) 2006-02-24 2011-07-19 The General Hospital Corporation Methods and systems for performing angle-resolved fourier-domain optical coherence tomography
JP4759425B2 (ja) * 2006-03-28 2011-08-31 オリンパス株式会社 多光子励起型観察装置
EP2004041B1 (de) 2006-04-05 2013-11-06 The General Hospital Corporation Verfahren, anordnungen und systeme für polarisationsempfindliche optische frequenzbereichsabbildung einer probe
WO2007130866A2 (en) 2006-05-02 2007-11-15 Quality Vision International, Inc. Laser range sensor system optics adapter and method
WO2007133961A2 (en) 2006-05-10 2007-11-22 The General Hospital Corporation Processes, arrangements and systems for providing frequency domain imaging of a sample
WO2007133964A2 (en) * 2006-05-12 2007-11-22 The General Hospital Corporation Processes, arrangements and systems for providing a fiber layer thickness map based on optical coherence tomography images
JP5112430B2 (ja) * 2006-06-29 2013-01-09 エージェンシー フォー サイエンス，テクノロジー アンド リサーチ マトリックス関連の組織動態及び疾患を定量するシステム及び方法
EP2069847B1 (de) * 2006-08-04 2013-03-06 The Government of the United States of America as represented by the Secretary of the Department of Health and Human Services Weitfeld-fluoreszenzdetektionssystem für multifotonen-mikroskopie
US7920271B2 (en) 2006-08-25 2011-04-05 The General Hospital Corporation Apparatus and methods for enhancing optical coherence tomography imaging using volumetric filtering techniques
US7706078B2 (en) 2006-09-14 2010-04-27 Semiconductor Energy Laboratory Co., Ltd. Laser light irradiation apparatus and laser light irradiation method
US7551359B2 (en) * 2006-09-14 2009-06-23 3M Innovative Properties Company Beam splitter apparatus and system
WO2008049118A2 (en) 2006-10-19 2008-04-24 The General Hospital Corporation Apparatus and method for obtaining and providing imaging information associated with at least one portion of a sample and effecting such portion(s)
US8155730B2 (en) * 2006-10-24 2012-04-10 The Research Foundation Of State University Of New York Composition, method, system, and kit for optical electrophysiology
DE102007035717A1 (de) * 2006-12-27 2008-07-03 Robert Bosch Gmbh Laserstrahlschweißvorrichtung sowie Laserstrahlschweißverfahren
WO2008089406A2 (en) 2007-01-19 2008-07-24 The General Hospital Corporation Apparatus and method for simultaneous inspection at different depths based on the principle of frequency domain optical coherence tomography
JP2010517080A (ja) 2007-01-19 2010-05-20 ザ ジェネラル ホスピタル コーポレイション 分散広帯域光の高速波長スキャンのための回転ディスク反射
EP2602651A3 (de) 2007-03-23 2014-08-27 The General Hospital Corporation Verfahren, Anordnungen und Vorrichtung zur Verwendung eines wellenlängengewobbelten Lasers anhand von Winkelabtastungs- und Dispersionsverfahren
US10534129B2 (en) 2007-03-30 2020-01-14 The General Hospital Corporation System and method providing intracoronary laser speckle imaging for the detection of vulnerable plaque
US8045177B2 (en) 2007-04-17 2011-10-25 The General Hospital Corporation Apparatus and methods for measuring vibrations using spectrally-encoded endoscopy
US8115919B2 (en) 2007-05-04 2012-02-14 The General Hospital Corporation Methods, arrangements and systems for obtaining information associated with a sample using optical microscopy
EP2173254A2 (de) 2007-07-31 2010-04-14 The General Hospital Corporation System und verfahren zur bereitstellung von strahlerfassungsmustern für hochgeschwindigkeits-abbildungen optischer dopplerfrequenzdomänen
WO2009029843A1 (en) 2007-08-31 2009-03-05 The General Hospital Corporation System and method for self-interference fluoresence microscopy, and computer-accessible medium associated therewith
JP5621259B2 (ja) * 2007-09-03 2014-11-12 株式会社ニコン 顕微鏡装置
GB0721343D0 (en) * 2007-10-30 2007-12-19 Perkinelmer Ltd Improvements in and relating to scanning confocal microscopy
US7933021B2 (en) 2007-10-30 2011-04-26 The General Hospital Corporation System and method for cladding mode detection
JP5038094B2 (ja) * 2007-10-31 2012-10-03 オリンパス株式会社 レーザー走査型顕微鏡
DE102007063274B8 (de) 2007-12-20 2022-12-15 Albert-Ludwigs-Universität Freiburg Mikroskop
US9332942B2 (en) 2008-01-28 2016-05-10 The General Hospital Corporation Systems, processes and computer-accessible medium for providing hybrid flourescence and optical coherence tomography imaging
US11123047B2 (en) 2008-01-28 2021-09-21 The General Hospital Corporation Hybrid systems and methods for multi-modal acquisition of intravascular imaging data and counteracting the effects of signal absorption in blood
EP2240763B1 (de) * 2008-02-04 2016-09-21 Koninklijke Philips N.V. Molekulares diagnosesystem, das auf evaneszenter beleuchtung und fluoreszenz beruht
JP5341111B2 (ja) * 2008-02-05 2013-11-13 リライアント・テクノロジーズ・リミテッド・ライアビリテイ・カンパニー アキシコン部を用いた光学的パターン生成器
EP2274572A4 (de) 2008-05-07 2013-08-28 Gen Hospital Corp System, verfahren und computermedium zur verfolgung einer gefässbewegung in einer dreidimensionalen koronararterienmikroskopie
WO2009155536A2 (en) 2008-06-20 2009-12-23 The General Hospital Corporation Fused fiber optic coupler arrangement and method for use thereof
JP5667051B2 (ja) 2008-07-14 2015-02-12 ザ ジェネラル ホスピタル コーポレイション カラー内視鏡検査のための装置
JP2010026165A (ja) * 2008-07-17 2010-02-04 Olympus Corp レーザー走査型顕微鏡
US10301912B2 (en) * 2008-08-20 2019-05-28 Foro Energy, Inc. High power laser flow assurance systems, tools and methods
US9229207B2 (en) * 2008-11-17 2016-01-05 Femtonics Kft Laser scanning microscope with focus-detecting unit
ES2957932T3 (es) 2008-12-10 2024-01-30 Massachusetts Gen Hospital Sistemas, aparatos y procedimientos para ampliar el rango de profundidad de imagen de tomografía de coherencia óptica mediante submuestreo óptico
JP2012515930A (ja) 2009-01-26 2012-07-12 ザ ジェネラル ホスピタル コーポレーション 広視野の超解像顕微鏡を提供するためのシステム、方法及びコンピューターがアクセス可能な媒体
CN102308444B (zh) 2009-02-04 2014-06-18 通用医疗公司 利用高速光学波长调谐源的设备和方法
WO2010105197A2 (en) 2009-03-12 2010-09-16 The General Hospital Corporation Non-contact optical system, computer-accessible medium and method for measuring at least one mechanical property of tissue using coherent speckle techniques(s)
US8194170B2 (en) * 2009-06-02 2012-06-05 Algonquin College Axicon lens array
US11490826B2 (en) 2009-07-14 2022-11-08 The General Hospital Corporation Apparatus, systems and methods for measuring flow and pressure within a vessel
WO2011047053A2 (en) * 2009-10-13 2011-04-21 California Institute Of Technology Holographically illuminated imaging devices
WO2011106327A2 (en) * 2010-02-23 2011-09-01 California Institute Of Technology High resolution imaging devices with wide field and extended focus
HUE051135T2 (hu) 2010-03-05 2021-03-01 Massachusetts Gen Hospital Rendszerek mikroszkópikus képek elõállítására legalább egy anatómiai szerkezetrõl adott felbontással
WO2011119678A2 (en) 2010-03-23 2011-09-29 California Institute Of Technology Super resolution optofluidic microscopes for 2d and 3d imaging
US9069130B2 (en) 2010-05-03 2015-06-30 The General Hospital Corporation Apparatus, method and system for generating optical radiation from biological gain media
US9557154B2 (en) 2010-05-25 2017-01-31 The General Hospital Corporation Systems, devices, methods, apparatus and computer-accessible media for providing optical imaging of structures and compositions
WO2011150069A2 (en) 2010-05-25 2011-12-01 The General Hospital Corporation Apparatus, systems, methods and computer-accessible medium for spectral analysis of optical coherence tomography images
WO2011153434A2 (en) 2010-06-03 2011-12-08 The General Hospital Corporation Apparatus and method for devices for imaging structures in or at one or more luminal organs
WO2012033957A2 (en) 2010-09-09 2012-03-15 California Institute Of Technology Delayed emission detection devices and methods
DE102010060121C5 (de) * 2010-10-22 2023-09-28 Leica Microsystems Cms Gmbh SPIM-Mikroskop mit sequenziellem Lightsheet
US9643184B2 (en) 2010-10-26 2017-05-09 California Institute Of Technology e-Petri dishes, devices, and systems having a light detector for sampling a sequence of sub-pixel shifted projection images
JP2013542468A (ja) * 2010-10-26 2013-11-21 カリフォルニア インスティチュート オブ テクノロジー 走査型投影レンズレス顕微鏡システム
US9569664B2 (en) 2010-10-26 2017-02-14 California Institute Of Technology Methods for rapid distinction between debris and growing cells
JP5883018B2 (ja) 2010-10-27 2016-03-09 ザ ジェネラル ホスピタル コーポレイション 少なくとも１つの血管内部の血圧を測定するための装置、システム、および方法
JP2012119098A (ja) * 2010-11-29 2012-06-21 Gigaphoton Inc 光学装置、レーザ装置および極端紫外光生成装置
US8749793B2 (en) * 2011-01-28 2014-06-10 Bwt Property, Inc. Apparatus and methods for performing Raman spectroscopy in scattering medium
KR20140027113A (ko) 2011-03-03 2014-03-06 캘리포니아 인스티튜트 오브 테크놀로지 도광 픽셀
US9086536B2 (en) 2011-03-09 2015-07-21 California Institute Of Technology Talbot imaging devices and systems
US8692998B2 (en) * 2011-04-11 2014-04-08 The Regents Of The University Of California Apparatus and method for light emission detection for in-depth imaging of turbid media
US8946619B2 (en) 2011-04-20 2015-02-03 California Institute Of Technology Talbot-illuminated imaging devices, systems, and methods for focal plane tuning
JP6240064B2 (ja) 2011-04-29 2017-11-29 ザ ジェネラル ホスピタル コーポレイション 散乱媒質の深さ分解した物理的及び／又は光学的特性を決定する方法
JP2014523536A (ja) 2011-07-19 2014-09-11 ザ ジェネラル ホスピタル コーポレイション 光コヒーレンストモグラフィーにおいて偏波モード分散補償を提供するためのシステム、方法、装置およびコンピュータアクセス可能な媒体
FR2978255B1 (fr) 2011-07-22 2014-02-21 Horiba Jobin Yvon Sas Dispositif optique d'eclairage conoscopique a cone creux pour microscope optique et procede de microscopie optique en conoscopie
EP2748587B1 (de) 2011-08-25 2021-01-13 The General Hospital Corporation Verfahren und anordnungen zur bereitstellung mikrooptischer kohärenztomographieverfahren
US9341783B2 (en) 2011-10-18 2016-05-17 The General Hospital Corporation Apparatus and methods for producing and/or providing recirculating optical delay(s)
FR2984531B1 (fr) 2011-12-20 2013-12-27 Ecole Polytech Microscopie optique non-lineaire quantitative utilisant un faisceau mis en forme
DE102011089557A1 (de) * 2011-12-22 2013-06-27 Hilti Aktiengesellschaft Lasersystem zur Erzeugung einer linienförmigen Lasermarkierung
CN102436066B (zh) * 2011-12-29 2013-07-17 江苏大学 一种可调空心光束内外径的方法与装置
WO2013148306A1 (en) 2012-03-30 2013-10-03 The General Hospital Corporation Imaging system, method and distal attachment for multidirectional field of view endoscopy
EP2852315A4 (de) 2012-05-21 2016-06-08 Gen Hospital Corp Einrichtung, vorrichtung und verfahren für kapselmikroskopie
US8964183B2 (en) * 2012-05-31 2015-02-24 General Electric Company Systems and methods for screening of biological samples
US9201008B2 (en) 2012-06-26 2015-12-01 Universite Laval Method and system for obtaining an extended-depth-of-field volumetric image using laser scanning imaging
EP2888616A4 (de) 2012-08-22 2016-04-27 Gen Hospital Corp System, verfahren, und über computer zugängliches medium zur herstellung eines miniaturendoskops mit weicher lithografie
EP2754524B1 (de) 2013-01-15 2015-11-25 Corning Laser Technologies GmbH Verfahren und Vorrichtung zum laserbasierten Bearbeiten von flächigen Substraten, d.h. Wafer oder Glaselement, unter Verwendung einer Laserstrahlbrennlinie
US10893806B2 (en) 2013-01-29 2021-01-19 The General Hospital Corporation Apparatus, systems and methods for providing information regarding the aortic valve
WO2014121082A1 (en) 2013-02-01 2014-08-07 The General Hospital Corporation Objective lens arrangement for confocal endomicroscopy
JP2014178357A (ja) * 2013-03-13 2014-09-25 Sony Corp デジタル顕微鏡装置、その撮像方法およびプログラム
EP2967491B1 (de) 2013-03-15 2022-05-11 The General Hospital Corporation Ein transösophageales endoskopisches system zur bestimmung einer gemischten venösen sauerstoffsättigung einer lungenarterie
EP2781296B1 (de) 2013-03-21 2020-10-21 Corning Laser Technologies GmbH Vorrichtung und verfahren zum ausschneiden von konturen aus flächigen substraten mittels laser
US9291825B2 (en) 2013-03-22 2016-03-22 Applied Materials Israel, Ltd. Calibratable beam shaping system and method
US9874736B2 (en) * 2013-04-29 2018-01-23 The Regents Of The University Of California Apparatus and method for an inclined single plane imaging microscope box (iSPIM box)
US9784681B2 (en) 2013-05-13 2017-10-10 The General Hospital Corporation System and method for efficient detection of the phase and amplitude of a periodic modulation associated with self-interfering fluorescence
WO2015010133A1 (en) 2013-07-19 2015-01-22 The General Hospital Corporation Determining eye motion by imaging retina. with feedback
EP3692887B1 (de) 2013-07-19 2024-03-06 The General Hospital Corporation Bildgebungsvorrichtung mithilfe von endoskopie mit multidirektionalem sichtfeld
US9668652B2 (en) 2013-07-26 2017-06-06 The General Hospital Corporation System, apparatus and method for utilizing optical dispersion for fourier-domain optical coherence tomography
US11556039B2 (en) 2013-12-17 2023-01-17 Corning Incorporated Electrochromic coated glass articles and methods for laser processing the same
US9517963B2 (en) 2013-12-17 2016-12-13 Corning Incorporated Method for rapid laser drilling of holes in glass and products made therefrom
WO2015105870A1 (en) 2014-01-08 2015-07-16 The General Hospital Corporation Method and apparatus for microscopic imaging
US10736494B2 (en) 2014-01-31 2020-08-11 The General Hospital Corporation System and method for facilitating manual and/or automatic volumetric imaging with real-time tension or force feedback using a tethered imaging device
US11780029B2 (en) 2014-03-05 2023-10-10 Panasonic Connect North America, division of Panasonic Corporation of North America Material processing utilizing a laser having a variable beam shape
US11204506B2 (en) 2014-03-05 2021-12-21 TeraDiode, Inc. Polarization-adjusted and shape-adjusted beam operation for materials processing
WO2015153982A1 (en) 2014-04-04 2015-10-08 The General Hospital Corporation Apparatus and method for controlling propagation and/or transmission of electromagnetic radiation in flexible waveguide(s)
EP3155469B1 (de) * 2014-06-11 2020-11-11 Dodt, Hans-Ulrich Lichtblattmikroskopie mit meso-optischen elementen
TWI730945B (zh) 2014-07-08 2021-06-21 美商康寧公司 用於雷射處理材料的方法與設備
TWI659793B (zh) * 2014-07-14 2019-05-21 美商康寧公司 用於使用可調整雷射束焦線來處理透明材料的系統及方法
JP2017525435A (ja) 2014-07-25 2017-09-07 ザ ジェネラル ホスピタル コーポレイション インビボ・イメージングおよび診断のための機器、デバイスならびに方法
DE102014220101A1 (de) * 2014-10-02 2016-04-07 Osram Gmbh Behandeln von Licht mittels einer optischen Einrichtung
CN104297925B (zh) * 2014-10-11 2016-07-13 北京工业大学 一种实现飞秒激光长焦深的折衍混合元件的设计方法
US9245803B1 (en) * 2014-10-17 2016-01-26 Applied Materials, Inc. Hybrid wafer dicing approach using a bessel beam shaper laser scribing process and plasma etch process
DE102015201639B4 (de) * 2015-01-30 2018-01-04 Asphericon Gmbh Strahlfokussierer und Verwendungen
EP3268715A1 (de) 2015-03-11 2018-01-17 Timothy Ragan System und verfahren zur seriellen färbung und bildgebung
EP3274306B1 (de) 2015-03-24 2021-04-14 Corning Incorporated Laserschneiden und verarbeiten von anzeigeglaszusammensetzungen
US10794998B2 (en) * 2015-06-29 2020-10-06 University Corporation For Atmospheric Research Diode laser based high spectral resolution lidar
US10295838B1 (en) * 2015-09-30 2019-05-21 Apple Inc. Body including surface having concentric annular portions
TWI581886B (zh) * 2015-12-11 2017-05-11 財團法人金屬工業研究發展中心 微結構加工裝置
CN106994562A (zh) * 2016-01-25 2017-08-01 郑钧文 硬脆材料的激光切割方法及激光切割机
DE102016107595B4 (de) * 2016-04-25 2018-12-13 Precitec Gmbh & Co. Kg Strahlformungsoptik für Materialbearbeitung mittels eines Laserstrahls sowie Vorrichtung mit derselben
DE112017003592T5 (de) * 2016-07-15 2019-03-28 TeraDiode, Inc. Materialbearbeitung unter Verwendung eines Lasers mit variabler Strahlform
WO2018029678A1 (en) * 2016-08-07 2018-02-15 Ramot At Tel-Aviv University Ltd. Method and system for imaging internal medium
KR102078294B1 (ko) 2016-09-30 2020-02-17 코닝 인코포레이티드 비-축대칭 빔 스폿을 이용하여 투명 워크피스를 레이저 가공하기 위한 기기 및 방법
US10416471B2 (en) * 2016-10-17 2019-09-17 Cymer, Llc Spectral feature control apparatus
US10394008B2 (en) 2016-10-19 2019-08-27 Cornell University Hyperspectral multiphoton microscope for biomedical applications
EP3848333A1 (de) 2016-10-24 2021-07-14 Corning Incorporated Substratverarbeitungsstation zur laserbasierten verarbeitung von flächigen glassubstraten
JP2018180016A (ja) 2017-04-03 2018-11-15 オリンパス株式会社 光検出装置およびレーザ顕微鏡システム
KR20180128647A (ko) * 2017-05-24 2018-12-04 삼성전자주식회사 광학 측정 방법 및 장치, 및 이를 이용한 반도체 장치의 제조 방법
US11511483B2 (en) 2017-06-30 2022-11-29 Nikon Corporation Method for manufacturing an article made of a polymerized material
CN107515209A (zh) * 2017-10-02 2017-12-26 西南石油大学 一种多功能荧光样品发光测试台
CN108195804A (zh) * 2017-12-12 2018-06-22 濮阳光电产业技术研究院 一种荧光探测器
JP7291959B2 (ja) * 2018-05-09 2023-06-16 国立研究開発法人理化学研究所 光学装置及び光音響顕微鏡
CN110361365A (zh) * 2019-02-03 2019-10-22 北京理工大学 一种扫描荧光成像装置及应用其的便携式qpcr装置
CN110174770B (zh) * 2019-03-18 2023-10-27 首都师范大学 一种轴上多段稳定传输贝塞尔光束的产生装置及方法
DE102019209057A1 (de) * 2019-06-24 2020-12-24 Robert Bosch Gmbh LIDAR-Vorrichtung
CN113495062A (zh) * 2020-04-07 2021-10-12 旭臻科技有限公司 用于大面积显微光致荧光扫描与测绘测量的***
CN111948145A (zh) * 2020-07-21 2020-11-17 南昌大学 一种基于超声调制的贝塞尔光束大景深光声显微成像装置及方法
KR102375235B1 (ko) * 2020-09-08 2022-03-16 주식회사 필옵틱스 레이저 가공 시스템 및 방법
CN117396123A (zh) * 2021-05-14 2024-01-12 利多普蒂克公司 用于可重新配置的光学内窥镜导管的方法和装置
CN116560096A (zh) * 2022-01-30 2023-08-08 贝克曼库尔特生物科技（苏州）有限公司 用于样本处理仪的光学***和样本处理仪
CN114994929B (zh) * 2022-05-27 2023-04-18 湖北大学 一种产生圆形平顶光束的装置
CN115644804B (zh) * 2022-09-29 2023-08-18 浙江浙大西投脑机智能科技有限公司 一种基于钙成像恢复算法的双光子成像方法及***
CN116429695B (zh) * 2023-05-09 2024-06-21 无锡启烨生物科技有限公司 一种具有可变束调光光源的微流生化分析仪
CN116893525B (zh) * 2023-09-07 2023-12-15 清华大学 远场超分辨光学***、激光制造***及成像分析***

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2759393A (en) * 1952-10-25 1956-08-21 Eastman Kodak Co Optical aligners employing axicons
US3999855A (en) * 1974-10-24 1976-12-28 Block Engineering, Inc. Illumination system
US4179708A (en) * 1978-02-27 1979-12-18 Rca Corporation Optical playback system having increased depth-of-field
US4623776A (en) * 1985-01-03 1986-11-18 Dow Corning Corporation Ring of light laser optics system
US4887592A (en) * 1987-06-02 1989-12-19 Hanspeter Loertscher Cornea laser-cutting apparatus
JP2915919B2 (ja) * 1989-03-21 1999-07-05 聡 河田 レーザ走査蛍光顕微鏡
US5034613A (en) * 1989-11-14 1991-07-23 Cornell Research Foundation, Inc. Two-photon laser microscopy
JPH03166531A (ja) * 1989-11-27 1991-07-18 Pioneer Electron Corp ファイバー型光波長変換装置
US5080456A (en) * 1990-02-26 1992-01-14 Symbol Technologies, Inc. Laser scanners with extended working range

Also Published As

Publication number Publication date
EP0627643B1 (de) 1999-05-06
DE69418248T2 (de) 1999-10-14
EP0627643A2 (de) 1994-12-07
US5583342A (en) 1996-12-10
US5796112A (en) 1998-08-18
EP0627643A3 (de) 1995-04-12

Similar Documents

Publication Publication Date Title
DE69418248D1 (de) Optisches Laser-Abtastsystem mit Axikon
DE69428950D1 (de) Optisches Abtastsystem
DE69406947D1 (de) Gekoppelter faserlaser mit mehreren ausgängen
DE69328385D1 (de) Optisches Abtastgerät
DE69324622D1 (de) Optisches Strahlabtastgerät
DE69618689D1 (de) Optisches System mit reflektierenden Flächen
DE69410595D1 (de) Aktiver laseroptischer mehrpunkt-lasersensor
DE69301759D1 (de) Laserstrahltaster
DE69432625D1 (de) Faseroptische verbindungsanordnung
DE69326213D1 (de) Optischer Abtastkopf
DE69315871D1 (de) Optisches Abtastsystem mit Hyperauflösung
DE69317731D1 (de) Optischer Abtastkopf
DE69424361D1 (de) Optischer Kodeabtaster
DE69411789D1 (de) Optischer Wellenleiter
DE69104762D1 (de) Optisches Abtastsystem.
DE69212133D1 (de) Optischer Abtaster
DE69423020D1 (de) Optischer Abtaster und Entfernungsmesser
DE69127963D1 (de) Optisches Abtastsystem
DE69310119D1 (de) Optisches Abtastsystem
DE69402453D1 (de) Optisches Abtastsystem
DE69315738D1 (de) Optischer Abtaster
DE69132683D1 (de) Optisches Abtastsystem
DE69412301D1 (de) Optisches Abtastgerät
DE69219910D1 (de) Lichtstrahlabtastsystem
DE69503001D1 (de) Optisches Abtastsystem

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee