DE69231298D1 - Substituierte Dibenzoxazepinverbindungen, pharmazeutische Zusammensetzungen und Anwendungsmethoden - Google Patents
Substituierte Dibenzoxazepinverbindungen, pharmazeutische Zusammensetzungen und AnwendungsmethodenInfo
- Publication number
- DE69231298D1 DE69231298D1 DE69231298T DE69231298T DE69231298D1 DE 69231298 D1 DE69231298 D1 DE 69231298D1 DE 69231298 T DE69231298 T DE 69231298T DE 69231298 T DE69231298 T DE 69231298T DE 69231298 D1 DE69231298 D1 DE 69231298D1
- Authority
- DE
- Germany
- Prior art keywords
- pharmaceutical compositions
- methods
- formula
- dibenzoxazepine compounds
- substituted dibenzoxazepine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US69565491A | 1991-05-03 | 1991-05-03 |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69231298D1 true DE69231298D1 (de) | 2000-08-31 |
DE69231298T2 DE69231298T2 (de) | 2001-01-18 |
Family
ID=24793923
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69231298T Expired - Fee Related DE69231298T2 (de) | 1991-05-03 | 1992-04-16 | Substituierte Dibenzoxazepinverbindungen, pharmazeutische Zusammensetzungen und Anwendungsmethoden |
DE69229442T Expired - Fee Related DE69229442T2 (de) | 1991-05-03 | 1992-04-16 | Substituierte dibenzooxazepin-verbindungen, pharmazeutische zusammensetzungen und verfahren zur verwendung |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69229442T Expired - Fee Related DE69229442T2 (de) | 1991-05-03 | 1992-04-16 | Substituierte dibenzooxazepin-verbindungen, pharmazeutische zusammensetzungen und verfahren zur verwendung |
Country Status (12)
Country | Link |
---|---|
EP (5) | EP0583421B1 (de) |
JP (1) | JP3222891B2 (de) |
AT (2) | ATE194987T1 (de) |
AU (1) | AU2246292A (de) |
CA (1) | CA2108903C (de) |
DE (2) | DE69231298T2 (de) |
DK (2) | DK0694545T3 (de) |
ES (2) | ES2149305T3 (de) |
GR (2) | GR3030992T3 (de) |
IE (2) | IE20000774A1 (de) |
PT (2) | PT911331E (de) |
WO (1) | WO1992019617A2 (de) |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5182272A (en) * | 1991-05-03 | 1993-01-26 | G. D. Searle & Co. | 8-substituted-dibenz[b,f][1,4]oxazepine-10(11)-carboxylic acid, substituted hydrazides, pharmaceutical compositions, and methods for treating pain |
US5180720A (en) * | 1991-05-03 | 1993-01-19 | G. D. Searle & Co. | 2- and 3-alkoxy or hydroxy-8-substituted-dibenz[b,f]-[1,4]oxazepine-10(11H)-carboxylic acid, substituted hydrazides and methods for treating pain |
US5378840A (en) * | 1992-04-16 | 1995-01-03 | G. D. Searle & Co. | Substituted dibenzoxazepine compounds |
US5212169A (en) * | 1991-10-31 | 1993-05-18 | G. D. Searle & Co. | Substituted dibenzoxazepine compounds, pharmaceutical compositions and methods for treating pain |
US5304644A (en) * | 1992-04-15 | 1994-04-19 | G. D. Searle & Co. | 1-,2-,3-,4-,5-,6-,7-,8- and/or 9 substituted dibenzoxazepine compounds, pharmaceutical compositions and methods for treating pain |
CA2113787A1 (en) * | 1993-01-29 | 1994-07-30 | Nobuyuki Hamanaka | Carbocyclic sulfonamides |
US5395932A (en) * | 1993-04-30 | 1995-03-07 | G. D. Searle & Co. | 2,3-,4-,5-,6-,7-,8-,9- and/or 10-substituted dibenzoxazepine compounds, pharmaceutical compositions and methods of use |
US5354746A (en) * | 1993-06-01 | 1994-10-11 | G. D. Searle & Co. | Squaric acid derivatives of substituted dibenzoxazepine compounds, pharmaceutical compositions and methods of use |
US5461047A (en) * | 1993-06-16 | 1995-10-24 | G. D. Searle & Co. | 2-,3-,4-,5-,6-,7-,8-,9- and/or 10-substituted dibenzoxazepine and dibenzthiazepine compounds, pharmaceutical compositions and methods of use |
US5354747A (en) * | 1993-06-16 | 1994-10-11 | G. D. Searle & Co. | 2-, 3-, 4-, 5-, 6-, 7-, 8-, 9- and/or 10-substituted dibenzoxazepine and dibenzthiazepine compounds, pharmaceutical compositions and methods of use |
US5420270A (en) * | 1993-10-07 | 1995-05-30 | G. D. Searle & Co. | Aryl substituted dibenzoxazepine compounds, pharmaceutical compositions and methods of use |
US5424424A (en) * | 1993-10-07 | 1995-06-13 | G. D. Searle & Co. | Tartaric acid derivatives of substituted dibenzoxazepine compounds, pharmaceutical compositions and methods of use |
US5488046A (en) * | 1993-11-03 | 1996-01-30 | G. D. Searle & Co. | Carbamic acid derivatives of substituted dibenzoxazepine compounds, pharmaceutical compositions and methods of use |
US5449675A (en) * | 1994-06-09 | 1995-09-12 | G. D. Searle & Co. | Substituted dibenzoxazepine and dibenzthiazepine urea compounds, pharmaceutical compositions and methods of use |
US5441950A (en) * | 1994-06-09 | 1995-08-15 | G. D. Searle & Co. | Substituted dibenzoxazepine and dibenzthiazepine carbamate compounds, pharmaceutical compositions and methods of use |
GB9720270D0 (en) | 1997-09-25 | 1997-11-26 | Pharmagene Lab Limited | Medicaments for the treatment of migraine |
CA2440374A1 (en) | 2001-03-14 | 2002-09-19 | Takayuki Maruyama | A pharmaceutical composition for the treatment of depression comprising the ep1 antagonist as active ingredient |
EP1447096A1 (de) * | 2001-11-19 | 2004-08-18 | Ono Pharmaceutical Co., Ltd. | Mittel zur behandlung von harndrang |
JO2735B1 (en) | 2003-01-30 | 2013-09-15 | هيلسين هيلث كير أس ايه. | Liquid pharmaceutical formations of balloonosterone |
US8598219B2 (en) | 2003-01-30 | 2013-12-03 | Helsinn Healthcare Sa | Liquid pharmaceutical formulations of palonosetron |
US8710045B2 (en) | 2004-01-22 | 2014-04-29 | The Trustees Of Columbia University In The City Of New York | Agents for preventing and treating disorders involving modulation of the ryanodine receptors |
RU2452479C2 (ru) | 2007-02-16 | 2012-06-10 | Оно Фармасьютикал Ко., Лтд. | Терапевтический агент при нарушении мочевыделения |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3624104A (en) * | 1969-10-27 | 1971-11-30 | Searle & Co | Aralkanoyl derivatives of dibenzoxazepine-n-carboxylic acid hydrazides |
US3917649A (en) * | 1971-03-23 | 1975-11-04 | Searle & Co | Dibenzoxazepine N-carboxylic acid hydrazides and derivatives |
GB1522003A (en) * | 1975-10-17 | 1978-08-23 | Searle & Co | 1-acyl-2-(8-chloro-10,11-dihydrodibenz-(b,f)(1,4)-oxazepine-10-carbonyl)hydrazines |
US4045442A (en) * | 1976-01-05 | 1977-08-30 | G. D. Searle & Co. | 1-(Substituted amino)alkanoyl-2-(dibenzoxazepine-10-carbonyl)hydrazines and derivatives thereof |
US4704386A (en) * | 1985-08-29 | 1987-11-03 | G. D. Searle & Co. | 8-chlorodibenz[b,f][1,4]oxazepine-10(11H)-carboxylic acid, 2-[(phenylsulfinyl-, and phenylsulfonyl)alkanoyl]hydrazides |
-
1992
- 1992-04-16 DK DK95116871T patent/DK0694545T3/da active
- 1992-04-16 ES ES95116871T patent/ES2149305T3/es not_active Expired - Lifetime
- 1992-04-16 AT AT95116871T patent/ATE194987T1/de not_active IP Right Cessation
- 1992-04-16 DE DE69231298T patent/DE69231298T2/de not_active Expired - Fee Related
- 1992-04-16 JP JP51183892A patent/JP3222891B2/ja not_active Expired - Fee Related
- 1992-04-16 EP EP92914560A patent/EP0583421B1/de not_active Expired - Lifetime
- 1992-04-16 DK DK92914560T patent/DK0583421T3/da active
- 1992-04-16 CA CA002108903A patent/CA2108903C/en not_active Expired - Fee Related
- 1992-04-16 ES ES92914560T patent/ES2133324T3/es not_active Expired - Lifetime
- 1992-04-16 EP EP95116871A patent/EP0694545B1/de not_active Expired - Lifetime
- 1992-04-16 WO PCT/US1992/003028 patent/WO1992019617A2/en active IP Right Grant
- 1992-04-16 DE DE69229442T patent/DE69229442T2/de not_active Expired - Fee Related
- 1992-04-16 AT AT92914560T patent/ATE181329T1/de not_active IP Right Cessation
- 1992-04-16 AU AU22462/92A patent/AU2246292A/en not_active Abandoned
- 1992-04-29 PT PT99101029T patent/PT911331E/pt unknown
- 1992-04-29 EP EP95116872A patent/EP0694546B1/de not_active Expired - Lifetime
- 1992-04-29 EP EP99101029A patent/EP0911331B1/de not_active Expired - Lifetime
- 1992-04-29 PT PT95116872T patent/PT694546E/pt unknown
- 1992-04-29 EP EP92107328A patent/EP0512400B1/de not_active Expired - Lifetime
- 1992-07-01 IE IE20000774A patent/IE20000774A1/en not_active IP Right Cessation
- 1992-07-01 IE IE141092A patent/IE921410A1/en not_active IP Right Cessation
-
1999
- 1999-08-18 GR GR990402070T patent/GR3030992T3/el unknown
-
2000
- 2000-10-20 GR GR20000402337T patent/GR3034650T3/el not_active IP Right Cessation
Also Published As
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |