DK0694545T3 - Substituerede dibenzoxazepinforbindelser, farmaceutiske sammensætninger og anvendelsesmetoder - Google Patents

Substituerede dibenzoxazepinforbindelser, farmaceutiske sammensætninger og anvendelsesmetoder

Info

Publication number
DK0694545T3
DK0694545T3 DK95116871T DK95116871T DK0694545T3 DK 0694545 T3 DK0694545 T3 DK 0694545T3 DK 95116871 T DK95116871 T DK 95116871T DK 95116871 T DK95116871 T DK 95116871T DK 0694545 T3 DK0694545 T3 DK 0694545T3
Authority
DK
Denmark
Prior art keywords
pharmaceutical compositions
methods
formula
dibenzoxazepine compounds
substituted dibenzoxazepine
Prior art date
Application number
DK95116871T
Other languages
Danish (da)
English (en)
Inventor
E Ann Hallinan
Hoeck Jean Pierre Van
Timothy Joseph Hagen
Robert Knol Husa
Sofya Tsymbalov
Albert C Lee
Original Assignee
Searle & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Searle & Co filed Critical Searle & Co
Application granted granted Critical
Publication of DK0694545T3 publication Critical patent/DK0694545T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
DK95116871T 1991-05-03 1992-04-16 Substituerede dibenzoxazepinforbindelser, farmaceutiske sammensætninger og anvendelsesmetoder DK0694545T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US69565491A 1991-05-03 1991-05-03

Publications (1)

Publication Number Publication Date
DK0694545T3 true DK0694545T3 (da) 2000-09-18

Family

ID=24793923

Family Applications (2)

Application Number Title Priority Date Filing Date
DK92914560T DK0583421T3 (da) 1991-05-03 1992-04-16 Substituerede dibenzoxazepinforbindelser, lægemidler og fremgangsmåder til anvendelse
DK95116871T DK0694545T3 (da) 1991-05-03 1992-04-16 Substituerede dibenzoxazepinforbindelser, farmaceutiske sammensætninger og anvendelsesmetoder

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK92914560T DK0583421T3 (da) 1991-05-03 1992-04-16 Substituerede dibenzoxazepinforbindelser, lægemidler og fremgangsmåder til anvendelse

Country Status (12)

Country Link
EP (5) EP0694545B1 (de)
JP (1) JP3222891B2 (de)
AT (2) ATE194987T1 (de)
AU (1) AU2246292A (de)
CA (1) CA2108903C (de)
DE (2) DE69229442T2 (de)
DK (2) DK0583421T3 (de)
ES (2) ES2133324T3 (de)
GR (2) GR3030992T3 (de)
IE (2) IE20000774A1 (de)
PT (2) PT694546E (de)
WO (1) WO1992019617A2 (de)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5182272A (en) * 1991-05-03 1993-01-26 G. D. Searle & Co. 8-substituted-dibenz[b,f][1,4]oxazepine-10(11)-carboxylic acid, substituted hydrazides, pharmaceutical compositions, and methods for treating pain
US5180720A (en) * 1991-05-03 1993-01-19 G. D. Searle & Co. 2- and 3-alkoxy or hydroxy-8-substituted-dibenz[b,f]-[1,4]oxazepine-10(11H)-carboxylic acid, substituted hydrazides and methods for treating pain
US5378840A (en) * 1992-04-16 1995-01-03 G. D. Searle & Co. Substituted dibenzoxazepine compounds
US5212169A (en) * 1991-10-31 1993-05-18 G. D. Searle & Co. Substituted dibenzoxazepine compounds, pharmaceutical compositions and methods for treating pain
US5304644A (en) * 1992-04-15 1994-04-19 G. D. Searle & Co. 1-,2-,3-,4-,5-,6-,7-,8- and/or 9 substituted dibenzoxazepine compounds, pharmaceutical compositions and methods for treating pain
CA2113787A1 (en) * 1993-01-29 1994-07-30 Nobuyuki Hamanaka Carbocyclic sulfonamides
US5395932A (en) * 1993-04-30 1995-03-07 G. D. Searle & Co. 2,3-,4-,5-,6-,7-,8-,9- and/or 10-substituted dibenzoxazepine compounds, pharmaceutical compositions and methods of use
US5354746A (en) * 1993-06-01 1994-10-11 G. D. Searle & Co. Squaric acid derivatives of substituted dibenzoxazepine compounds, pharmaceutical compositions and methods of use
US5461047A (en) * 1993-06-16 1995-10-24 G. D. Searle & Co. 2-,3-,4-,5-,6-,7-,8-,9- and/or 10-substituted dibenzoxazepine and dibenzthiazepine compounds, pharmaceutical compositions and methods of use
US5354747A (en) * 1993-06-16 1994-10-11 G. D. Searle & Co. 2-, 3-, 4-, 5-, 6-, 7-, 8-, 9- and/or 10-substituted dibenzoxazepine and dibenzthiazepine compounds, pharmaceutical compositions and methods of use
US5424424A (en) * 1993-10-07 1995-06-13 G. D. Searle & Co. Tartaric acid derivatives of substituted dibenzoxazepine compounds, pharmaceutical compositions and methods of use
US5420270A (en) * 1993-10-07 1995-05-30 G. D. Searle & Co. Aryl substituted dibenzoxazepine compounds, pharmaceutical compositions and methods of use
US5488046A (en) * 1993-11-03 1996-01-30 G. D. Searle & Co. Carbamic acid derivatives of substituted dibenzoxazepine compounds, pharmaceutical compositions and methods of use
US5449675A (en) * 1994-06-09 1995-09-12 G. D. Searle & Co. Substituted dibenzoxazepine and dibenzthiazepine urea compounds, pharmaceutical compositions and methods of use
US5441950A (en) * 1994-06-09 1995-08-15 G. D. Searle & Co. Substituted dibenzoxazepine and dibenzthiazepine carbamate compounds, pharmaceutical compositions and methods of use
GB9720270D0 (en) 1997-09-25 1997-11-26 Pharmagene Lab Limited Medicaments for the treatment of migraine
WO2002072145A1 (fr) * 2001-03-14 2002-09-19 Ono Pharmaceutical Co., Ltd. Remedes antidepresseurs contenant un antagoniste ep1 en tant que principe actif
US20060100195A1 (en) * 2001-11-19 2006-05-11 Takayuki Maruyama Remedies for urinary frequency
US8598219B2 (en) 2003-01-30 2013-12-03 Helsinn Healthcare Sa Liquid pharmaceutical formulations of palonosetron
JO2735B1 (en) 2003-01-30 2013-09-15 هيلسين هيلث كير أس ايه. Liquid pharmaceutical formations of balloonosterone
US8710045B2 (en) 2004-01-22 2014-04-29 The Trustees Of Columbia University In The City Of New York Agents for preventing and treating disorders involving modulation of the ryanodine receptors
WO2008099907A1 (ja) 2007-02-16 2008-08-21 Ono Pharmaceutical Co., Ltd. 尿排出障害治療剤

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3624104A (en) * 1969-10-27 1971-11-30 Searle & Co Aralkanoyl derivatives of dibenzoxazepine-n-carboxylic acid hydrazides
US3917649A (en) * 1971-03-23 1975-11-04 Searle & Co Dibenzoxazepine N-carboxylic acid hydrazides and derivatives
GB1522003A (en) * 1975-10-17 1978-08-23 Searle & Co 1-acyl-2-(8-chloro-10,11-dihydrodibenz-(b,f)(1,4)-oxazepine-10-carbonyl)hydrazines
US4045442A (en) * 1976-01-05 1977-08-30 G. D. Searle & Co. 1-(Substituted amino)alkanoyl-2-(dibenzoxazepine-10-carbonyl)hydrazines and derivatives thereof
US4704386A (en) * 1985-08-29 1987-11-03 G. D. Searle & Co. 8-chlorodibenz[b,f][1,4]oxazepine-10(11H)-carboxylic acid, 2-[(phenylsulfinyl-, and phenylsulfonyl)alkanoyl]hydrazides

Also Published As

Publication number Publication date
ES2133324T3 (es) 1999-09-16
DE69231298D1 (de) 2000-08-31
EP0694546A2 (de) 1996-01-31
JP3222891B2 (ja) 2001-10-29
EP0694545A2 (de) 1996-01-31
EP0512400B1 (de) 1998-12-02
WO1992019617A3 (en) 1992-12-10
WO1992019617A2 (en) 1992-11-12
IE20000774A1 (en) 2001-02-21
JPH06507408A (ja) 1994-08-25
PT911331E (pt) 2004-03-31
EP0694546B1 (de) 2001-06-06
ATE181329T1 (de) 1999-07-15
EP0694545B1 (de) 2000-07-26
EP0512400A1 (de) 1992-11-11
GR3034650T3 (en) 2001-01-31
DE69229442D1 (de) 1999-07-22
CA2108903A1 (en) 1992-11-04
EP0583421A1 (de) 1994-02-23
DE69231298T2 (de) 2001-01-18
ATE194987T1 (de) 2000-08-15
EP0583421B1 (de) 1999-06-16
CA2108903C (en) 2004-02-10
EP0694546A3 (de) 1996-03-27
EP0911331A2 (de) 1999-04-28
GR3030992T3 (en) 1999-12-31
PT694546E (pt) 2001-09-28
EP0694545A3 (de) 1996-03-27
EP0911331B1 (de) 2003-10-22
ES2149305T3 (es) 2000-11-01
AU2246292A (en) 1992-12-21
DE69229442T2 (de) 1999-10-28
IE921410A1 (en) 1992-11-04
DK0583421T3 (da) 1999-11-22
EP0911331A3 (de) 2000-01-19

Similar Documents

Publication Publication Date Title
DK0694545T3 (da) Substituerede dibenzoxazepinforbindelser, farmaceutiske sammensætninger og anvendelsesmetoder
CY1111951T1 (el) Φαινυλο-καρβοξαμιδικες ενωσεις χρησιμες για την αντιμετωπιση πονου
ES2106531T3 (es) Compuestos de dibenzoxazepina substituidos en 2, 3, 4, 5, 6, 7, 8, 9 y/o 10, composiciones farmaceuticas y metodos de uso.
NO923199D0 (no) Terapeutiske forbindelser
FI923664A0 (fi) Piperidinderivat.
MD1560G2 (ro) Compuşi ciclici, compoziţii farmaceutice pe baza lor şi metode de tratament al infecţiilor sau bolilor provocate de retrovirusuri
ES2134313T3 (es) Utilizacion de derivados de pregnano para el tratamiento de tumores.
FI923662A (fi) Terapeutiska medel